新着論文紹介

2023.10.2Vaccination with short-term-cultured autologous PBMCs efficiently activated STLV-1-specific CTLs in naturally STLV-1-infected Japanese monkeys with impaired CTL responses.
Hasegawa A, et. al., PLoS Pathog (2023)
2023.10.2Dual targeting of aberrant DNA and histone methylation synergistically suppresses tumor cell growth in ATL.
Kurahashi Y, et. al., Blood Adv (2022)
2023.10.2Increasing horizontal transmission of human T-cell leukemia virus type 1 in adolescents and young adults in Japan.
Sagara Y, et. al., J Clin Virol (2022)
2023.10.2CARD11 mutation and HBZ expression induce lymphoproliferative disease and adult T-cell leukemia/lymphoma.
Kameda T, et. al., Commun Biol (2022)
2023.10.2Establishment of a Cynomolgus Macaque Model of Human T-Cell Leukemia Virus Type 1 (HTLV-1) Infection by Direct Inoculation of Adult T-Cell Leukemia Patient- Derived Cell Lines for HTLV-1 Infection.
Urano E, et. al., J Virol (2022)
2023.10.2Frequency of HTLV-1 seroconversion between pregnancies in Nagasaki, Japan, 2011-2018.
Komatsu N, et. al., Front Microbiol (2022)
2023.10.2Potential role of HTLV-1 Tax-specific cytotoxic t lymphocytes expressing a unique t-cell receptor to promote inflammation of the central nervous system in myelopathy associated with HTLV-1.
Tanaka Y, et. al., Front Immunol (2022)
2023.10.2RAISING is a high-performance method for identifying random transgene integration sites.
Wada Y, et. al., Commun Biol (2022)
2023.10.2The Association of Increase of Human T-Cell Leukemia Virus Type-1 (HTLV-1) Proviral Load (PVL) With Infection in HTLV-1-Positive Patients With Rheumatoid Arthritis: A Longitudinal Analysis of Changes in HTLV-1 PVLs in a Single Center Cohort Study.
Iwamoto N, et. al., Front Immunol (2022)
2023.10.2Identification and characterization of a novel enhancer in the HTLV-1 proviral genome.
Matsuo M, et. al., Nat Commun (2022)
2023.10.2Cytolytic Recombinant Vesicular Stomatitis Viruses Expressing STLV-1 Receptor Specifically Eliminate STLV-1 Env-Expressing Cells in an HTLV-1 Surrogate Model In Vitro.
Seki Y, et. al., Viruses (2022)
2023.10.2HTLV-1 uveitis and Graves' disease presenting with sudden onset of blurred vision.
Kamoi K, et. al., Lancet (2022)
2023.10.2M-Sec induced by HTLV-1 mediates an efficient viral transmission.
Hiyoshi M, et. al., PLoS Pathog (2021)
2023.10.2Recent Prevalence of Human T-cell Leukemia Virus Type 1 Carrier Associated with Horizontal Transmission in Pregnant Japanese Women.
Suzuki S, et. al., Jpn J Infect Dis (2021)
2023.10.2Epidemiology of adult T-cell leukemia-lymphoma in Japan: An updated analysis, 2012-2013.
Ito S, et. al., Cancer Sci (2021)
2023.10.2Mother-to-Child Transmission of Human T-Cell Leukemia Virus Type 1: Mechanisms and Nutritional Strategies for Prevention.
Itabashi K, Miyazawa T., Cancers (Basel) (2021)
2023.10.2Chronological genome and single-cell transcriptome integration characterizes the evolutionary process of adult T cell leukemia-lymphoma.
Yamagishi M, et. al., Nat Commun (2021)
2023.10.2The Effect of Early Postnatal Nutrition on Human T Cell Leukemia Virus Type 1 Mother-to-Child Transmission: A Systematic Review and Meta-Analysis.
Miyazawa T, et. al., Viruses (2021)
2023.10.2Human retroviral antisense mRNAs are retained in the nuclei of infected cells for viral persistence.
Ma G, et. al., Proc Natl Acad Sci U S A (2021)
2023.10.2Anti-Human T-Cell Leukemia Virus Type 1 (HTLV-1) Antibody Assays in Cerebrospinal Fluid for the Diagnosis of HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis.
Kodama D, et. al., J Clin Microbiol (2021)
2023.10.2Horizontal transmission of HTLV-1 causing uveitis.
Kamoi K, et. al., Lancet Infect Dis (2021)
2023.10.2Genome wide association study of HTLV-1-associated myelopathy/tropical spastic paraparesis in the Japanese population.
Penova M, et. al., Proc Natl Acad Sci U S A (2021)
2023.10.2Human T-Cell Leukemia Virus Type 1 Infection Is a Risk Factor for Atherosclerosis.
Takeoka H, et. al., J Clin Med Res (2021)
2023.10.2Genetic profile of adult T-cell leukemia/lymphoma in Okinawa: Association with prognosis, ethnicity, and HTLV-1 strains.
Sakihama S, et. al., Cancer Sci (2021)
2023.10.2論文解説In vivo dynamics and adaptation of HTLV-1-infected clones under different clinical conditions.
Izaki M, et. al., PLoS Pathog (2021)
2023.10.2Estimation of the window period of human T-cell leukemia virus type 1and 2 tests by a lookback study of seroconverters among Japanese voluntary blood donors.
Sagara Y, et. al., Transfusion (2021)
2023.10.2Clinical significance of soluble CADM1 as a novel marker for adult T-cell leukemia/lymphoma.
Nakahata S, et. al., Haematologica (2021)
2023.10.2Clinicopathological features of adult T-cell leukemia/lymphoma with HTLV-1-infected Hodgkin and Reed-Sternberg-like cells.
Karube K, et. al., Blood Adv (2021)
2023.10.2Prognosis of patients with adult T-cell leukemia/lymphoma in Japan: A nationwide hospital-based study.
Imaizumi Y, et. al., Cancer Sci (2020)
2023.10.2Tackling HTLV-1 infection in ophthalmology: a nationwide survey of ophthalmic care in an endemic country, Japan.
Kamoi K, et. al., Br J Ophthalmol (2020)
2023.10.2HTLV-1 targets human placental trophoblasts in seropositive pregnant women.
Tezuka K, et. al., J Clin Invest (2020)
2023.10.2Establishment of a novel diagnostic test algorithm for human T-cell leukemia virus type 1 infection with line immunoassay replacement of western blotting: a collaborative study for performance evaluation of diagnostic assays in Japan.
Okuma K, et. al., Retrovirology (2020)
2023.10.2Implementation of nationwide screening of pregnant women for HTLV-1 infection in Japan: analysis of a repeated cross-sectional study.
Yonemoto N, et. al., BMC Public Health (2020)
2023.10.2Hodgkin and Reed-Sternberg-like cells infected with human T-cell leukemia virus type 1.
Tsuruta Y, Karube K., Blood (2020)
2023.10.2Frequent horizontal and mother-to-child transmission may contribute to high prevalence of STLV-1 infection in Japanese macaques.
Murata M, et. al., Retrovirology (2020)
2023.10.2HTLV-1 induces T cell malignancy and inflammation by viral antisense factor-mediated modulation of the cytokine signaling.
Higuchi Y, et. al., Proc Natl Acad Sci U S A. (2020)
2023.10.2Mortality and risk of progression to adult T cell leukemia/lymphoma in HTLV-1-associated myelopathy/tropical spastic paraparesis.
Nagasaka M, et. al., Proc Natl Acad Sci U S A (2020)
2023.10.2Activation of PERK-ATF4-CHOP pathway as a novel therapeutic approach for efficient elimination of HTLV-1-infected cells.
Ikebe E, et. al., Blood Adv (2020)
2023.10.2A Nationwide Antenatal Human T-Cell Leukemia Virus Type-1 Antibody Screening in Japan.
Itabashi K, et. al., Front Microbiol (2020)
2023.10.2論文解説Proteomic profiling of HTLV-1 carriers and ATL patients reveals sTNFR2 as a novel diagnostic biomarker for acute ATL.
Guerrero CLH, et. al., Blood Adv (2020)
2023.3.24 Lower prevalence of anti‐HTLV‐1 as expected by previous models among first‐time blood donors in Japan
Satake M, Sagara Y, Hamaguchi I, Journal of Medical Virology (2023)
2020.10.19 論文解説 Frosted branch angiitis after allogeneic haematopoieticstem cell transplantation in adult T-cell leukaemia-lymphoma
成人T細胞白血病における同種造血幹細胞移植後に起こる樹氷状網膜血管炎

Kamoi K, et al., THE LANCET Haematology (2020)
2020.9.11 論文解説Establishment of a novel diagnostic test algorithm for human T-cell leukemia virus type 1 infection with line immunoassay replacement of western blotting: a collaborative study for performance evaluation of diagnostic assays in Japan.
ウエスタンブロット法の代替法としてのラインブロット法を用いたヒトT細胞白血病ウイルス1型感染の新規診断検査アルゴリズムの確立:日本における診断検査性能評価のための共同研究

Kazu Okuma, et al., Retrovirology (2020)
2019.1.18 論文解説Development of reference material with assigned value for human T-cell leukemia virus type 1 quantitative PCR in Japan
HTLV-1定量PCRの参照品の開発

Kuramitsu M. et al. Microbiology and Immunology (2018)
2018.3.15 論文解説Mogamulizumab (Anti-CCR4) in HTLV-1-Associated Myelopathy.
HTLV-1関連脊髄症におけるモガムリズマブ(抗CCR4抗体)

Sato T, et al., N Engl J Med. (2018)
2016.12.1 論文解説Dysregulation of c-Myb pathway by aberrant expression of proto-oncogene MYB provides the basis for malignancy in adult T-cell leukemia/lymphoma cells
Proto-oncogene MYB遺伝子発現異常によるc-Myb経路撹乱がATL細胞悪性化形質を規定する

Nakano K, et al., Clinical Cancer Research (2016)
2016.11.25 論文解説Incidence of human T-lymphotropic virus 1 infection in adolescent and adult blood donors in Japan: a nationwide retrospective cohort analysis.
日本の青年期・成人献血者における新規HTLV-1感染の実態

Satake M, et al., Lancet Infectious Disease (2016)
2016.5.30 論文解説CCR4 frameshift mutation identifies a distinct group of adult T cell leukaemia/lymphoma with poor prognosis.
ATLLにおけるCCR4変異に基づく臨床病理解析

Yoshida N, et al., The Journal of Pathology (2016)
2016.5.30 論文解説Standardization of Quantitative PCR for Human T-Cell Leukemia Virus Type 1 in Japan: a Collaborative Study.
HTLV-1核酸定量の標準化:多施設共同研究

Madoka Kuramitsu, et al., Journal of Clinical Microbiology (2015)
2016.5.12 論文解説Treatment and survival among 1594 patients with ATL.
2000年以降に診断されたATL患者の治療実態と予後

Katsuya H, et al., Blood (2016)
2016.5.12 論文解説The retrovirus HTLV-1 inserts an ectopic CTCF-binding site into the human genome
HTLV-1によるヒトゲノムへの異所性CTCF結合部位挿入

Satou Y, et al., Proc Natl Acad Sci U S A (2016)
2016.5.6 論文解説Polycomb-dependent epigenetic landscape in adult T-cell leukemia
ATL細胞のエピゲノム異常の実態

Fujikawa D, et al., Blood (2016)
2015.10.28 論文解説Integrated molecular analysis of adult T-cell leukemia/lymphoma
ATLの包括的分子解析

Kataoka K, et al., Nature Genetics, (2015)

 

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