現在までの佐渡プロジェクトの研究成果です．
- 2024年
- 1.Lyu H, Sugita N, Komatsu S, Wakasugi M, Yokoseki A, Yoshihara A, Kobayashi
T, Sato K, Kawashima H, Onodera O, Narita I, Tabeta K.
- UCP2 polymorphisms, daily step count, and number of teeth associated with all-cause mortality risk in Sado City: A hospital-based cohort study
- Heliyon. 2024 Jun 8;10(12):e32512. doi: 10.1016/j.heliyon.2024.e32512. eCollection 2024 Jun 30.
- UCP2 polymorphisms, daily step count, and number of teeth associated with all-cause mortality risk in Sado City: A hospital-based cohort study
- 2023年
- 1.Wakasugi M, Yokoseki A, Wada M, Yoshino T, Momotsu T, Sato K, Kawashima
H, Nakamura K, Fukuchi T, Onodera O, Narita.
- Cataract Surgery and Chronic Kidney Disease: A Hospital-based Prospective Cohort Study
- Intern Med. 2023 Sep 29. doi: 10.2169/internalmedicine.2176-23. Online ahead of print.
- 2.Wakasugi M, Yokoseki A, Wada M, Momotsu T, Sato K, Kawashima H, Nakamura K, Onodera O, Narita I.
- Vegetable and fruit intake frequency and mortality in patients with and without CKD: A hospital-based cohort study
- J Ren Nutr. 2023 Feb 13;S1051-2276(23)00021-3. doi: 10.1053/j.jrn.2023.01.011. Online ahead of print..
- Cataract Surgery and Chronic Kidney Disease: A Hospital-based Prospective Cohort Study
- 2022年
- Wakasugi M, Yokoseki A, Wada M, Sanpei K, Momotsu T, Sato K, Kawashima
H, Nakamura K, Onodera O, Narita I.
- Stroke incidence and chronic kidney disease: A hospital-based prospective cohort study.
- Nephrology (Carlton). 2022 Apr 29. doi: 10.1111/nep.14049. Online ahead of print. PMID: 35488413
- Stroke incidence and chronic kidney disease: A hospital-based prospective cohort study.
- 2021年
- Wakasugi M, Yokoseki A, Wada M, Momotsu T, Sato K, Kawashima H, Nakamura
K, Onodera O, Narita I.
- Polypharmacy, chronic kidney disease, and incident fragility fracture: a prospective cohort study.
- J Bone Miner Metab. 2021 Nov 3. doi: 10.1007/s00774-021-01272-9. Online ahead of print. PMID: 34729651
- Polypharmacy, chronic kidney disease, and incident fragility fracture: a prospective cohort study.
- 2020年
- 1.Takamisawa K, Sugita N, Komatsu S, Wakasugi M, Yokoseki A, Yoshihara
A, Kobayashi T, Nakamura K, Onodera O, Momotsu T, Endo N, Sato K, Narita
I, Yoshie H, Tabeta K.
- Association between serum IgG antibody titers against Porphyromonas gingivalis and liver enzyme levels: A cross-sectional study in Sado Island.
- Heliyon. 2020 Nov 18;6(11):e05531. doi: 10.1016/j.heliyon.2020.e05531. eCollection 2020 Nov.
- Association between serum IgG antibody titers against Porphyromonas gingivalis and liver enzyme levels: A cross-sectional study in Sado Island.
- 2019年
- 1.Morita Y, Sasaki T, Takahashi K, Kitazawa M, Nonomura Y, Yagi C, Yamagishi
T, Ohshima S, Izumi S, Wakasugi M, Yokoseki A, Narita I, Endo N, Horii
A.
- Age-related Hearing Loss Is Strongly Associated With Cognitive Decline Regardless of the APOE4 Polymorphism.
- Otol Neurotol. 2019 Oct 28. doi: 10.1097/MAO.0000000000002415. [Epub ahead of print]
- 2.Misawa K, Watanabe H, Yokoseki A, Wakasugi M, Onodera O, Narita I, Momotsu T, Sato K, Endo N.
- Is the population of Sado Island genetically close to the population of western Japan?
- Hum Genome Var. 2019 Jun 4;6:26. doi: 10.1038/s41439-019-0058-6. eCollection 2019.
- Age-related Hearing Loss Is Strongly Associated With Cognitive Decline Regardless of the APOE4 Polymorphism.
- 2018年
- 1.Kuroki A, Sugita N, Komatsu S, Wakasugi M, Yokoseki A, Yoshihara A, Kobayashi
T, Nakamura K, Momotsu T, Endo N, Sato K, Narita I, Yoshie H.
- The number of remaining teeth as a risk indicator of cognitive impairment: A cross-sectional clinical study in Sado Island.
- Clin Exp Dent Res. 2018 Nov 30;4(6):291-296. doi: 10.1002/cre2.147. eCollection 2018 Dec.
- 2.Sakuma M, Kitamura K, Endo N, Ikeuchi T, Yokoseki A, Onodera O, Oinuma T, Momotsu T, Sato K, Nakamura K, Narita I.
- Low serum 25-hydroxyvitamin D increases cognitive impairment in elderly people.
- J Bone Miner Metab. 2019 Mar;37(2):368-375. doi: 10.1007/s00774-018-0934-z. Epub 2018 Jun 14.
- 3.Kuroki A, Sugita N, Komatsu S, Yokoseki A, Yoshihara A, Kobayashi T, Nakamura K, Momotsu T, Endo N, Sato K, Narita I, Yoshie H.
- Association of Liver enzyme levels and alveolar bone loss: A cross-sectional clinical study in Sado Island
- J Clin Exp Dent. 2018 Feb 1;10(2):e100-e106. doi: 10.4317/jced.54555. eCollection 2018 Feb
- The number of remaining teeth as a risk indicator of cognitive impairment: A cross-sectional clinical study in Sado Island.
- 2017年
- 1.Watanabe Y, Kitamura K, Nakamura K, Sanpei K, Wakasugi M, Yokoseki A,
Kabasawa K, Onodera O, Ikeuchi T, Kuwano R, Momotsu T, Narita I, Endo N
- Association between dialysis treatment and cognitive decline: A study from the Project in Sado for Total Health (PROST), Japan.
- Geriatr Gerontol Int. 2017 Oct;17(10):1584-1587. doi: 10.1111/ggi.12937. Epub 2016 Nov 21.
- Association between dialysis treatment and cognitive decline: A study from the Project in Sado for Total Health (PROST), Japan.
- 2016年
- 1.Watanabe Y, Kitamura K, Nakamura K, Sanpei K, Wakasugi M, Yokoseki A,
Kabasawa K, Onodera O, Ikeuchi T, Kuwano R, Momotsu T, Narita I, Endo N.
- Association between dialysis treatment and cognitive decline: A study from the Project in Sado for Total Health (PROST), Japan.
- Geriatr Gerontol Int. 2016 Nov 21. doi: 10.1111/ggi.12937. [Epub ahead of print]
- 2.Kitamura K, Watanabe Y, Nakamura K, Sanpei K, Wakasugi M, Yokoseki A, Onodera O, Ikeuchi T, Kuwano R, Momotsu T, Narita I, Endo N.
- Modifiable Factors Associated with Cognitive Impairment in 1,143 Japanese Outpatients: The Project in Sado for Total Health (PROST).
- Dement Geriatr Cogn Dis Extra. 2016 Aug 12;6(2):341-349.
- 3.Watanabe Y, Kitamura K, Nakamura K, Sanpei K, Wakasugi M, Yokoseki A, Onodera O, Ikeuchi T, Kuwano R, Momotsu T, Narita I, Endo N.
- Elevated C-Reactive Protein Is Associated with Cognitive Decline in Outpatients of a General Hospital: The Project in Sado for Total Health (PROST).
- Dement Geriatr Cogn Dis Extra. 2016 Jan 19;6(1):10-9. doi: 10.1159/000442585.
- 4.Yagihara N, Watanabe H, Barnett P, Duboscq-Bidot L, Thomas AC, Yang P, Ohno S, Hasegawa K, Kuwano R, Chatel S, Redon R, Schott JJ, Probst V, Koopmann TT, Bezzina CR, Wilde AA, Nakano Y, Aiba T, Miyamoto Y, Kamakura S, Darbar D, Donahue BS, Shigemizu D, Tanaka T, Tsunoda T, Suda M, Sato A, Minamino T, Endo N, Shimizu W, Horie M, Roden DM, Makita N.
- Variants in the SCN5A Promoter Associated With Various Arrhythmia Phenotypes.
- J Am Heart Assoc. 2016 Sep 13;5(9). pii: e003644. doi: 10.1161/JAHA.116.003644.
- 5.Nozaki H, Kato T, Nihonmatsu M, Saito Y, Mizuta I, Noda T, Koike R, Miyazaki K, Kaito M, Ito S, Makino M, Koyama A, Shiga A, Uemura M, Sekine Y, Murakami A, Moritani S, Hara K, Yokoseki A, Kuwano R, Endo N, Momotsu T, Yoshida M, Nishizawa M, Mizuno T, Onodera O.
- Distinct molecular mechanisms of HTRA1 mutants in manifesting heterozygotes with CARASIL.
- Neurology. 2016 May 24;86(21):1964-74. doi: 10.1212/WNL.0000000000002694.
- Association between dialysis treatment and cognitive decline: A study from the Project in Sado for Total Health (PROST), Japan.
- 2015年
- 1.Watanabe H, Goto S, Miyashita A, Maruyama H, Wakasugi M, Yokoseki A,
Kuwano R, Narita I.
- Role of the p.E66Q variant of GLA in the progression of chronic kidney disease.
- Clin Exp Nephrol. 2015 Apr;19(2):225-30. doi: 10.1007/s10157-014-0969-y.
- Role of the p.E66Q variant of GLA in the progression of chronic kidney disease.
- 2014年
- 1.Makita N, Yagihara N, Crotti L, Johnson CN, Beckmann BM, Roh MS, Shigemizu
D, Lichtner P, Ishikawa T, Aiba T, Homfray T, Behr ER, Klug D, Denjoy I,
Mastantuono E, Theisen D, Tsunoda T, Satake W, Toda T, Nakagawa H, Tsuji
Y, Tsuchiya T, Yamamoto H, Miyamoto Y, Endo N, Kimura A, Ozaki K, Motomura
H, Suda K, Tanaka T, Schwartz PJ, Meitinger T, Kääb S, Guicheney P, Shimizu
W, Bhuiyan ZA, Watanabe H, Chazin WJ, George AL Jr.
- Novel calmodulin mutations associated with congenital arrhythmia susceptibility.
- Circ Cardiovasc Genet. 2014 Aug;7(4):466-74. doi: 10.1161/CIRCGENETICS.113.000459.
- 2.Sakuma M, Endo N, Oinuma T, Miyasaka D, Oguma Y, Imao K, Koga H, Tanabe N.
- Incidence of osteoporotic fractures in Sado, Japan in 2010.
- J Bone Miner Metab. 2014 Mar;32(2):200-5. doi: 10.1007/s00774-013-0486-1.
- Novel calmodulin mutations associated with congenital arrhythmia susceptibility.
- 2013年
- 1.Bezzina CR, Barc J, Mizusawa Y, Remme CA, Gourraud JB, Simonet F, Verkerk
AO, Schwartz PJ, Crotti L, Dagradi F, Guicheney P, Fressart V, Leenhardt
A, Antzelevitch C, Bartkowiak S, Borggrefe M, Schimpf R, Schulze-Bahr E,
Zumhagen S, Behr ER, Bastiaenen R, Tfelt-Hansen J, Olesen MS, Kääb S, Beckmann
BM, Weeke P, Watanabe H, Endo N, Minamino T, Horie M, Ohno S, Hasegawa
K, Makita N, Nogami A, Shimizu W, Aiba T, Froguel P, Balkau B, Lantieri
O, Torchio M, Wiese C, Weber D, Wolswinkel R, Coronel R, Boukens BJ, Bézieau
S, Charpentier E, Chatel S, Despres A, Gros F, Kyndt F, Lecointe S, Lindenbaum
P, Portero V, Violleau J, Gessler M, Tan HL, Roden DM, Christoffels VM,
Le Marec H, Wilde AA, Probst V, Schott JJ, Dina C, Redon R.
- Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death.
- Nat Genet. 2013 Sep;45(9):1044-9. doi: 10.1038/ng.2712.
- 2.Nakano Y, Chayama K, Ochi H, Toshishige M, Hayashida Y, Miki D, Hayes CN, Suzuki H, Tokuyama T, Oda N, Suenari K, Uchimura-Makita Y, Kajihara K, Sairaku A, Motoda C, Fujiwara M, Watanabe Y, Yoshida Y, Ohkubo K, Watanabe I, Nogami A, Hasegawa K, Watanabe H, Endo N, Aiba T, Shimizu W, Ohno S, Horie M, Arihiro K, Tashiro S, Makita N, Kihara Y.
- A nonsynonymous polymorphism in semaphorin 3A as a risk factor for human unexplained cardiac arrest with documented ventricular fibrillation.
- PLoS Genet. 2013 Apr;9(4):e1003364. doi: 10.1371/journal.pgen.1003364.
- 3.Wakasugi M, Kazama JJ, Yamamoto S, Kawamura K, Narita I.
- A combination of healthy lifestyle factors is associated with a decreased incidence of chronic kidney disease: a population-based cohort study.
- Hypertens Res. 2013 Apr;36(4):328-33. doi: 10.1038/hr.2012.186.
- Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death.
- 2012年
- Wakasugi M, Kawamura K, Yamamoto S, Kazama JJ, Narita I.
- High mortality rate of infectious diseases in dialysis patients: a comparison with the general population in Japan.
- Ther Apher Dial. 2012 Jun;16(3):226-31. doi: 10.1111/j.1744-9987.2012.01062.x.
- Wakasugi M, Kazama JJ, Narita I.
- Differences in the local and national prevalences of chronic kidney disease based on annual health check program data.
- Clin Exp Nephrol. 2012 Oct;16(5):749-54. doi: 10.1007/s10157-012-0628-0.
- Wakasugi M, Kazama JJ, Narita I.
- Use of Japanese Society for Dialysis Therapy dialysis tables to compare the local and national incidence of dialysis.
- Ther Apher Dial. 2012 Feb;16(1):63-7. doi: 10.1111/j.1744-9987.2011.01030.x.
- High mortality rate of infectious diseases in dialysis patients: a comparison with the general population in Japan.
- 2011年
- Shiga A, Nozaki H, Yokoseki A, Nihonmatsu M, Kawata H, Kato T, Koyama A,
Arima K, Ikeda M, Katada S, Toyoshima Y, Takahashi H, Tanaka A, Nakano
I, Ikeuchi T, Nishizawa M, Onodera O.
- Cerebral small-vessel disease protein HTRA1 controls the amount of TGF-β1 via cleavage of proTGF-β1.
- Hum Mol Genet. 2011 May 1;20(9):1800-10. doi: 10.1093/hmg/ddr063.
- Cerebral small-vessel disease protein HTRA1 controls the amount of TGF-β1 via cleavage of proTGF-β1.
- 2010年
- Oinuma T, Sakuma M, Endo N.
- Secular change of the incidence of four fracture types associated with senile osteoporosis in Sado, Japan: the results of a 3-year survey.
- J Bone Miner Metab. 2010;28(1):55-9. doi: 10.1007/s00774-009-0097-z.
- Secular change of the incidence of four fracture types associated with senile osteoporosis in Sado, Japan: the results of a 3-year survey.
- 2008年
- Sakuma M, Endo N, Oinuma T, Endo E, Yazawa T, Watanabe K, Watanabe S.
- Incidence and outcome of osteoporotic fractures in 2004 in Sado City, Niigata Prefecture, Japan.
- J Bone Miner Metab. 2008;26(4):373-8. doi: 10.1007/s00774-007-0841-1
- Incidence and outcome of osteoporotic fractures in 2004 in Sado City, Niigata Prefecture, Japan.