京都府立医科大学 法医学教室 Department of Forensics Medicine , Kyoto Prefectural University of Medicine
法医認定医研修施設A(日本法医学会)・Ai認定施設 施設A(オートプシー・イメージング学会)・小児死亡事例に対する死亡時画像診断モデル事業登録施設(日本医師会)・日本口腔科学会研修施設
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研究業績
2024年
Matsunari R, Kondou H, Ishikawa N, Miyamori D, Ikegaya H.
Estimation of cadaveric age in crime scenes using Raman spectroscopy.
J Forensic Leg Med. 2024 Feb:102:102642. doi: 10.1016/j.jflm.2024.102642.
Yamazaki E, Urata R, Ueno D, Katayama A, Ito F, Ikegaya H, Matoba S.
Endothelial CLEC-1b plays a protective role against cancer hematogenous metastasis.
Biochem Biophys Res Commun. 2024 Mar 22:708:149819. doi:10.1016/j.bbrc.2024.149819.
Kondou H, Morohashi R, Kimura S, Idota N, Matsunari R, Ichioka H, Bandou R, Kawamoto M, Deng T, Ikegaya H.
Artificial intelligence-based forensic sex determination of East Asian cadavers from skull morphology.
Scientific Reports. vol. 13, Article number: 21026 (2023) doi.org/10.1038/s41598-023-48363-3
Ichioka H,Saito U,Shintani-Ishida K,Shirahase T,Idota N, Kanamura N, Ikegaya H. Application of Teeth in Toxicological Analysis of Decomposed Cadavers Using a Carbamazepine-Administered Rat Model. Diagnostics 2023, 13(2), 311; https://doi.org/10.3390/diagnostics13020311
Ichioka H,Bandou R, Idota N,Shintani-Ishida K,Ikegaya H. Current Issues in Dental Identification in Severely Burned Bodies from a Studio Arson Attack in Japan. Appl. Sci. 2023, 13(1), 461; https://doi.org/10.3390/app13010461
Idota N, Kimura S, Bandou R, Ikegaya H.
Head injuries caused by hammer blows:A case report and literature review
Forensic Sci. Int.:Reports7(2023)100309
Miyamori D, Kondou H, Ichioka H, Matsunari R, Ikegaya H.
A suicide case by hanging without fixing the end of the rope
Legal Medicine Volume 63, July 2023, 102247
Kondou H, Morohashi R, Ichioka H, Bandou R, Matsunari R, Kawamoto M, Idota N, Deng T, Kimura S, Ikegaya H.
Deep neural networks-based age estimation of cadavers using CT imaging of vertebrae
Int. J. Environ. Res. Public Health 2023, 20(6), 4806; https://doi.org/10.3390/ijerph20064806
Minamiyama T, Kawamoto M, Matsunari R, Deng T, Ikegaya H.
Detection of human chorionic gonadotropin (HCG) in fabric urine stains older than five years.
J. Foreinsic Sci. 2023;68:1401-1404.
Shintani-Ishida K, Idota N, Tsuboi H, Tsurumi R, Ikegaya H. Pentobarbital overdose: a case of contract killing. Legal Medicine 59:102149 (2022).
Matsumoto M, Sawada H, Iwata K, Ibi M, Asaoka N, Katsuyama M, Shintani-Ishida K, Ikegaya H, Takegami S, Umemura A, Yabe-Nishimura C. Bortezomib is an effective enhancer for chemical probe-dependent superoxide detection. Front Med (Lausanne). 21(9):941180 (2022).
Shintani-Ishida K, Tsurumi R, Ikegaya H. Decrease in the expression of muscle-specific miRNAs, miR-133a and miR-1, in myoblasts with replicative senescence. PlosOne https://doi.org/10.1371/journal.pone.0280527 (2022).
Kondou H, Bandou R, Ichioka H, Matsunari R, Kawamoto M, Idota N, Deng T, Kimura S, Ikegaya H.
Examination of Postmortem β-Hydroxybutyrate Increase in Forensic Autopsy Cases.
Appl. Sci. 2022,12(14):7181. DOI:10.3390/app12147181
Kondou H, Ichioka H, Akasaka Y, Kondoh Hidehito, Ikegaya H.
Sudden death of a 2-year-old child due to alpha-ketoadipic aciduria.
Forensic Sci., Medicine and Pathology. 2022. DOI:10.1007/s12024-022-00483-4
Kondou H, Bandou R, Ichioka H, Idota N, Matsunari R, Kawamoto M, Ikegaya H.
Estimating the age at death for forensic cases using quantitative computed tomography.
Forensic Sci.Int. 2022,337:111367. DOI:10.1016/j.forsciint.2022.111367
Bandou R, Hirose R, Nakaya T, Miyazaki H, Watanabe N, Yoshida T, Daidoji T, Itoh Y, Ikegaya H.
Higher Viral Stability and Ethanol Resistance of Avian Influenza A(H5N1) Virus on Human Skin.
Emerg Infect Dis. 2022, 28(3):639-649. doi: 10.3201/eid2803.211752.
Miyamori D, Kamitani T, Ogawa Y, Idota N, Ikegaya H, Ito M, Yamamoto Y.
Alcohol abuse as a potential risk factor of solitary death among people living alone: a cross-sectional study in Kyoto, Japan.
BMC Public Health. 2022, 19;22(1):545. doi: 10.1186/s12889-022-12965-9.
Bandou R, Idota N, Akasaka Y, Ikegaya H.
A Case of Fatal Asphyxia by a Barbell during a Bench Press.
Forensic Sci. 2022,2(1)1-6
Bandou R, Ichioka H, Kawamoto M, Ikegaya H.
An Autopsy Case of Posterior Pharyngeal Abscesses Caused by Periodontal Bacteria.
Forensic Sci. 2022,2,399-402
Hiroki Kondou, Risa Bandou, Hiroaki Ichioka, Nozomi Idota, Hiroshi Ikegaya.The Coronary Artery Calcification Severity On Postmortem CT Could Be A Clue For the Diagnosis Of Sudden Cardiac Death.J. Forensic Leg Med. 82:102227. 2021. doi:10.1016/j.jflm.2021.102227
Daisuke Miyamori, Takeshi Uemura, Wenliang Zhu, Kei Fujikawa, Takaaki Nakaya, Satoshi Teramukai, Giuseppe Pezzotti & Hiroshi Ikegaya.A Raman algorithm to estimate human age from protein structural variations in autopsy skin samples: a protein biological clock.Sci Rep. 11: 5949 (2021). doi:10.1038/s41598-021-85371-7.
Hiroshi Ikegaya, Motofumi Suzuki, Hiroki Kondou, Taketo Kawai, Yusuke Sato, Tadaichi Kiramura, Haruki Kume.Nose size indicates maximum penile length.Basic and Clinical Andrology in press
Takeshima Y, Suzuki M, Ikegaya H, Idota N, Kawai T, Sato Y, Kume H. A cross-sectional cadaveric study of the correlation between genital organ measurements, serum testosterone, and serum prostate-specific antigen levels in Japanese male subjects. Int J Physiol Pathophysiol Pharmacol 2020. in press.
Hiroki Kondou, Hajime Tsuboi, Ryutaro Takazakura, Mami Nakamura, Risa Bandou, Hiroaki Ichioka, Nozomi Idota, Hiroshi Ikegaya.Diagnosis of sudden death using postmortem CT.Forensic Imaging, 23, 2020, 200411, https://doi.org/10.1016/j.fri.2020.200411.
Hirose R, Ikegaya H, Naito Y, Watanabe N, Yoshida T, Bandou R, Daidoji T, Itoh Y, Nakaya:Survival of SARS-CoV-2 and influenza virus on the human skin: Importance of hand hygiene in COVID-19. T.Clin Infect Dis. 2020 Oct 3:ciaa1517. doi: 10.1093/cid/ciaa1517. Online ahead of print.
Nakamura M, Shintani-Ishida K. A new role of peripheral serotonin on drug-induced hyperthermia at a high ambient temperature. Med Sci Digest 46(9): 38-40, 2020.
Uemura T, Akasaka Y, Ikegaya H. Correlation of polyamines, acrolein-conjugated lysine and polyamine metabolic enzyme levels with age in human liver.Heliyon. 2020: 6(9), e05031. https://doi.org/10.1016/j.heliyon.2020.e05031
Tsuboi H, Miyamori D, Ishikawa N, Ichioka H, Ikegaya H. Relationship between serum prostate specific antigen and age in cadavers. SAGE Open Medicine Volume 8: 1-7, 2020 .
Ichioka H, Miyamori D, Ishikawa N, Bandou R, Idota N, Kondou H, Ikegaya H.Estimation of Cadaveric Age by Ultrasonography.Diagnostics 2020, 10(7), 499; doi.org/10.3390/diagnostics10070499.
Miyamori D, Tanaka Y, Ishikawa N, Kitamura T, Ikegaya H.Population history in Okinawa based on JC virus and ALDH2 genotypes.Sci Rep. 10:7331 (2020) . doi: 10.1038/s41598-020-64194-y.
Nakamura M, Idota N, Shintani-Ishida K, Hitosugi M, Ikegaya H.
Simple, Frequent Indicator for Personal Identification-Postmortem and Antemortem Abdominal Computed Tomography Findings of a Charred Body.
Am J Forensic Med Pathol. 2020 Mar;41(1):56-59.
doi: 10.1097/PAF.0000000000000522.
2019年
Ichioka H, Bando R, Tsuboi H, Idota N, Kumagai W, Ikegaya H. Forensic dental identification of remains in five prefectures in the Kansai region of Japan. Oral Sci Int. 00:1?5 (2019). doi: 10.1002/osi2.1036.
Idota N, Nakamura M, Akasaka Y, Tsuboi H, Bando R, Ikegaya H. Perforation rates in double latex gloves and protective effects of outer work gloves in a postmortem examination room: A STROBE-compliant study.Medicine (Baltimore). 98(27):e16348 (2019). doi: 10.1097/MD.0000000000016348.
Idota N, Nakamura M, Tsuboi H, Ichioka H, Shintani-Ishida K, Ikegaya H.Autoerotic asphyxia using a plastic bag loosely covering the head over a gas mask.Legal Med. 38:69-72(2019)
Suzuki M,Ikegaya H,Idota N,Kawai T,Sato Y,Kume H. Penile size and stretched rate in a Japanese male population: A ross-sectional cadaveric study. Int J Urol. 26:936-937 (2019). doi: 10.1111/iju.14052. Epub 2019 Jul 14.
Tojo M, Shintani-Ishida K, Tsuboi H, Nakamura M, Idota N, Ikegaya H. Postmortem plasma pentraxin 3 is a useful marker of fatal acute coronary syndrome. Sci Rep. 9:8090 (2019). doi: 10.1038/s41598-019-44472-0.
Tsuboi H, Yokota I, Miyamori D, Akasaka Y, Yamada A, Ikegaya H. Age estimation based on visual parameters of the skin of cadavers. Skin Res Technol. 25:532-537 (2019). doi: 10.1111/srt.12683. Epub 2019 Feb 15.
Kinebuchi T, Idota N, Tsuboi H, Takaso M, Bando R, Ikegaya H. The genome profiling method can be applied for species identification of biological materials collected at crime scenes. BMC Genet. 20:50 (2019). doi: 10.1186/s12863-019-0753-9.
2018年
Hara J, Tanaka Y, Kaneko H, Itoh Y, Ikegaya H. Detection of hepatitis B virus DNA and HBsAg from postmortem blood and bloodstains. Arch Virol. 163:633-637 (2018). doi: 10.1007/s00705-017-3665-x. Epub 2017 Dec 2.
Adachi Y, Oyama D. Kawai J, Yamaguchi T, Shintani-Ishida K, Ikegaya H. Investigation of geomagnetic orientation preserved in a stain containing iron compounds using a vector-type SQUID magnetometer. IEE Transactions on Applied Superconductivity 28(4):1-4 (2018)
Idota N, Tsuboi H, Takaso M, Tojo M, Kinebuchi T, Nakamura M, Ichioka H, Shintani-Ishida K, Ikegaya H.Comparison between Temperature Gradient Gel Electrophoresis of Bacterial 16S rDNA and Diatom Test for Diagnosis of Drowning.J Forensic Sci. 2018 May;63(3):752-757. doi: 10.1111/1556-4029.13606. Epub 2017 Aug 2.
Shintani-Ishida K, Saka K, Nakamura M, Yoshida KI, Ikegaya H.Experimental Study on the Postmortem Redistribution of the Substituted Phenethylamine, 25B-NBOMe.J Forensic Sci. 2018 Mar;63(2):588-591. doi: 10.1111/1556-4029.13583. Epub 2017 Jun 23.
Idota N, Nakamura M, Tojo M, Ichioka H, Shintani-Ishida K, Ikegaya H.Infant fatality case with excessive chylous ascites.Leg Med (Tokyo).38:69-72(2018)
Miyamori D, Takaso M, Komeda N, Ishikawa N, Tsuboi H, Bando R, Ikegaya H.Relationship between thyroid and hormone levels and age in post-mortem caseds.Rom J Leg Med. 26:12-15(2018)
Takaso M, Tsuboi H, Komeda N, Morimoto M, Ikegaya H.Value of the serum thyroglobulin level for diagnosing neck compression in postmortem cases.Journal of Forensic and Legal Medicine. 58:126-129(2018)
Ishikawa N, Takaso M, Akasaka Y, Yamamoto H, Ikegaya H.The relationship between the intramuscular bleeding of the tongue and cause of death.Journal of Forensic and Legal Medicine. 59:50-55(2018)
Tsuboi H, Takazakura R, Idota N, Takaso M, Ikegaya H.Rare atlas fracture detected using postmortem computed tomography: A case report.Journal of Forensic and Legal Medicine.60:38-41(2018)
Nakamura M, Shintani-Ishida K, Ikegaya H. 5-HT 2A receptor agonist-induced hyperthermia is induced via vasoconstriction by peripheral 5-HT 2A receptors and brown adipose tissue thermogenesis by peripheral serotonin loss at a high ambient temperature.Journal of Pharmacology and Experimental Therapeutics 367:1-7 (2018).
Shintani-Ishida K, Tsuboi H, Ichioka H, Ikegaya H.Comparison of postmortem butane distribution between two fatal butane poisoning cases.Legal Med 35:69-72(2018)
Takamura A, Watanabe K, Akutsu T, Ikegaya H, Ozawa T. Spectral Mining for Discriminating Blood Origins in the Presence of Substrate Interference via Attenuated Total Reflection Fourier Transform Infrared Spectroscopy: Postmortem or Antemortem Blood? Anal Chem. 2017; 89:9797-9804. doi.org/10.1021/acs.analchem.7b01756.
Idota N, Nakamura M, Masui K, Kakiuchi Y, Yamada K, Ikegaya H. Lessons Learned from Autopsying an Unidentified Body with Iodine-125 Seeds Implanted for Prostate Brachytherapy.Journal of Forensic Sciences 2017; 62(2); 536-540. doi: 10.1111/1556-4029.13296.
Ikegaya H, McLean S, Ikka T, Kakiuchi K, Idota N. Public awareness of the use of clinical CT machines for postmortems.Journal of Forensic Radiology and Imaging 2017; 11;12-17. DOI: http://dx.doi.org/10.1016/j.jofri.2017.09.001.
Uemura T, Takasaka T, Igarashi K, Ikegaya H. Spermine oxidase promotes bile canalicular lumen formation through acrolein production.Scientific Reports 7(1);14841. 2017; doi:10.1038/s41598-017-14929-1.
2016年
Makino Y, Itoda N, Ikegaya H, Tanaka N, Kinoshita H, Motomura A, Uno T, Iwase H. Search and removal of radioactive seeds: another application of postmortem computed tomography prior to autopsy Int J Legal Med. 2016;130(5):1329-1332.doi:10.1007/s00414-016-1404-6
Nakamura M, Idota N, Shintani-Ishida K, Tojo M, Kakiuchi Y, Ikegaya H. Still without sales restriction Fatal caffeine toxicity a case report and review of the literature 日本アルコール・薬物医学会雑誌. 2016;51(3);221-227.
Nomura M, McLean S, Miyamori D, Kakiuchi Y, Ikegaya H. Isolation and unnatural death of elderly people in the aging Japanese society.Science & Justice.2016;56(2);80-83.doi:10.1016/j.scijus.2015.12.003
Shintani-Ishida K, Kakiuchi Y, Ikegaya H. Successful quantification of 4'-methyl-α-pyrrolidinohexanophenone(MPHP)in human urine using LC-TOF-MS in an autopsy case.Forensic Toxicol.2016;34:398-402.doi:10.1007/s11419-016-0307-z.
2015年
Kakiuchi Y, Idota N, Nakamura M, Ikegaya H An autopsy case of Group A Streptococcus meningoencephalitis Journal of Clinical Pathology and Forensic Medicine. 2015;6(2);6-10.doi:10.5897/JCPFM2015.0061
Ikka T, Fujita M, Yashiro Y, Ikegaya H.Recent Court Ruling in Japan Exemplifies Another Layer of Regulation for Regenerative Therapy.Cell stem Cell. 2015;17(5):507-508.
Pezzotti G, Boffelli M, Miyamori D, Uemura T, Marunaka Y, Zhu W, Ikegaya H.Raman spectroscopy of human skin: looking for a quantitative algorithm to reliably estimate human age.J Biomed Opt. 2015 Jun;20(6):065008. doi: 10.1117/1.JBO.20.6.065008.
Tanaka Y, Hirata R, Mashita K, McLean S, Ikegaya H.Detection of human polyomavirus DNA using the genome profiling method.The Open Virology Journal. 2015;9;29-37.
Miyamori D, Ishikawa N, Idota N, Kakiuchi Y, McLean S, Kitamura T, Ikegaya H.Tracing Jomon and Yayoi ancestries in Japan using ALDH2 and JC virus genotype distributions.Investigative Genetics. 2015;6:14.doi:10.1186/s13323-015-0031-1
Ishikawa N, Suganami H, Nishida A, Miyamori D, Kakiuchi Y, Yamada N, Wook-Cheol K, Kubo T, Ikegaya H.Utilization of bone impedance for age estimation in postmortem cases.J Forensic Leg Med. 2015.sep.14;36:102-107.
Kakiuchi Y, Idota N, Nakamura M, Ikegaya H.A Fatal Case of Cervical Hemorrhage After Fine Needle Aspiration and Core Needle Biopsy of the Thyroid Gland.Am J Forensic Med Pathol. 2015 Sep;36(3):207-9. doi: 10.1097/PAF.0000000000000172.
Shintani-Ishida K, Yoshida K. Mitochondrial m-calpain opens the mitochondrial permeability transition pore in ischemia-reperfusion.Int J Cardiol (2015;197;26-32).
Shintani-Ishida K, Nakamura M, Tojo M, Idota N, Ikegaya H. Identification and quantification of 4'-methoxy-α-pyrrolidinobutiophenone(4-MeOPBP)in human plasma and urine using LC-TOF-MS in an autopsy case. Forensic Toxicol 2015;33;348‐354.
Idota N, Kobayashi M, Miyamori D, Kakiuchi Y, Ikegaya H. Drospirenone detected in postmortem blood of a young woman with pulmonary thromboembolism:A case report and review of the literature. Legal Medicine. 2015;17(2);109-115.
Nishida A, Funaki H, Kobayashi M, Tanaka Y, Akasaka Y, Kubo T, Ikegaya H. Blood creatinine level in postmortem cases. Science & Justice. 2015;55(3);195-199.
Ogi H, Itoh K, Ikegaya H, Fushiki S. Alterations of neurotransmitter norepinephrine and gamma-aminobutyric acid correlate with murine behavioral perturbations related to bisphenol A exposure. Brain Dev. 37:739-746 (2015). doi: 10.1016/j.braindev.2014.12.008. Epub 2015 Jan 7.
Nara A, Nagai H, Shintani-Ishida K, Ogura S,Shimosawa T, Kuwahira I, Shirai M, Yoshida K. Pulmonary Arterial Hypertension in Rats Due to Age-related Arginase Activation in Intermittent Hypoxia. Am J Res Cell Mol Biol.2015;53(2);184-192.
Kuroda R, Shintani-Ishida K, Unuma K, Yoshida K. Immobilization stress with alpha2-adrenergic stimulation induces regional and transient reduction of cardiac contraction through Gi coupling in rats. Int Heart J 2015;56(5);537-543.
Yoshida K, Saka K, Shintani-Ishida K, Maeda H,Nakajima M, Hara S, Ueno M, Sasaki K, Iwase H, Sakamoto T. A case of fatal intoxication due to the new designer drug 25B-NBOMe. Forensic Toxicol 2015;33(2)348-354.
Shintani-ishida K, Saka K, Yamaguchi K, Hayashida M, Nagai H,Takemura G, Yoshida K. MDMA induces cardiac contractile dysfunction through autophagy upregulation and lysosome destabilization in rats. Biochim Biophys Acta. 1842(5):691-700(2014)
McLean S, Ikegaya H, Saukko PJ, Zheng HY, Itoh K, Fushiki S. The utilization of stable isotope analysis for the estimation of the geographic origins of unidentified cadavers. Forensic Sci.int. 2014;245;45-50.
Hashimoto M, Nakajima M, Kuroda R, Yamaguchi R, Maeda H, Nagai H, Ikegaya H, Yoshida K. Sudden unexpected death in a patient with epilepsy presenting with high N-terminal probrain natriuretic peptide level,cardiac lesions,and pulmonary edema. Int J Cardiol. 2014 Mar 15;172(2):e265-7.doi:10.1016/j.ijcard.2013.12.069.
Marunaka Y, Yoshimoto K, Aoi W, Hosogi S, Ikegaya H. Low pH of intersitial fluid around hippocampus of the brain in diabetic OLETF rats. Molecular and Cellular Therapies. 2014;2;6.
Sugimoto S, Nakajima H, Kodo K, Mori J, Matsuo K, Kosaka K, Aoi W,Yoshimoto K, Ikegaya H, Hosoi H.Miglitol increases energy expenditure by upregulating uncoupling protein 1 of brown adipose tissue and reduces obesity in dietary-induced obese mice.Nutrition & Metabolism. 2014;11;14.
Ikegaya H. Criminology. Update forensics for deaths in Japan.Nature. 2014 Mar 20;507(7492):306. doi: 10.1038/507306e.
Kashima J, Shintani-Ishida K, Nakajima M, Maeda H, Unuma K, Uchiyama Y,Yoshida K.Immunohistochemical study of the autophagy marker microtubule-associated protein 1 light chain 3(LC3)in normal and steatotic human livers. Hepatol Res. 2014; 44(7);779-787.
Nagai H, Maeda H, Kuroda, R, Komori M, Nakajima M, Nara A, Ito-Tsujimura T, Shintani-Ishida K, Yahagi N, Yoshida K.Lethal pulmonary air embolism caused by the removal of a double-lumen hemodialysis catheter. Am J Forensic Med Pathol. 2014;35(4);237-238.
Hashimoto M, Nakajima M, Kuroda R, Yamaguchi R, Maeda H, Nagai H, Ikegaya H, Yoshida K:Sudden unexpected death in a patient with epilepsy presenting with high N-terminal probrain natriuretic peptide level, cardiac lesions, and pulmonary edema.Int J Cardiol. 2014; 172(2); e265-7. doi: 10.1016/j.ijcard.2013.12.069. Epub 2013 Dec 31.
Inoue H, Motani-Saitoh H, Sakurada K, Ikegaya H, Yajima D, Nagasawa S, Iwase H:Genotypic polymorphisms of hepatitis B virus provide useful information for estimating geographical origin or place of long-term residence of unidentified cadavers.J Forensic Sci. 2014; 59(1);236-41. doi: 10.1111/1556-4029.12257. Epub 2013 Sep 10.
Miyamori D, Ishikawa N, Akasaka Y, Yamada K, Ikegaya H:Temporal evolution in peritoneal hemorrhage as depicted by postmortem CT. Forensic Legal Med. 2013;20;548-550.
Ishikawa N, Nishida A, Miyamori D, Kubo T, Ikegaya H:Estimation of postmortem time based on aorta narrowing in CT imaging.J Forensic Leg Med. 2013 Nov;20(8):1075-7. doi: 10.1016/j.jflm.2013.09.026. Epub 2013 Oct 9.
McLean SJ, Ikegaya H, Saukko PJ, Zheng HY, Akutsu T, Miyamori D, Ishikawa N, Sakurada K:A trial of the utilization of stable isotope analysis for the estimation of the geographic origins of unidentified cadavers.Forensic Sci Int. 2013 Oct 10;232(1-3):237.e1-5. doi: 10.1016/j.forsciint.2013.07.019. Epub 2013 Aug 2.
Hirata R, Takasaka T, Miyamori D, Ahmed S, Sakurada K, Nishigaki K, Ikegaya H:Use of the genome profiling method for the identification of saliva and sweat samples.Jpn J Forensic Sci Tech. 2013;18(1);79-83.
Uemura T, Tanaka Y, Higashi K, Miyamori D, Takasaka T, Nagano T, Toida T, Yoshimoto K, Igarashi K, Ikegaya H:Acetaldehyde-induced cytotoxicity involves induction of spermine oxidase at the transcriptional level.Toxicology. 2013 Aug 9;310:1-7. doi: 10.1016/j.tox.2013.05.008. Epub 2013 May 23.
Watanabe K, Hosoya M, Hirayama K, Saitoh H, Iwase H, Ikegaya H, Akutsu T, Sekiguchi K, Sakurada K:Forensic validation of the modified ABO genotyping method using a DNA chip.Leg Med (Tokyo). 2013 Jul;15(4):222-5. doi: 10.1016/j.legalmed.2013.01.004. Epub 2013 Mar 9.
Yoshimoto K, Ueda S, Kitamura Y, Inden M, Hattori H, Ishikawa N, McLean S, Ikegaya H: Administration of rotenone enhanced voluntary alcohol drinking behavior in C57BL/6J mice. Leg Med (Tokyo). 2012 ;14(5):229-38.
McLean S, Nanba H, Ikegaya H: Locational characteristics of the increasing number of forensic autopsy cases in Kyoto, Japan. Med Sci Law. 2012 ;52(2):96-9.
Suwa N, Ikegaya H, Takasaka T, Nishigaki K, Sakurada K: Human blood identification using the genome profiling method. Leg Med (Tokyo). 2012 ;14(3):121-5.
一家綱邦:「倫理委員会システムの1つの歴史:社会科学研究の自由と規律ZACHARY M. SCHRAG, ETHICAL IMPERIALISM: INSTITUTIONAL REVIEW BOARDS AND THE SOCIAL SCIENCES, 1965-2009」アメリカ法2011-2. 2012; 485-490
Sakabe M, Miyamori D, Mclean S, Shinmen N, Kato H, Yoshimoto K, Ikegaya H: The use of moxibustion scars in the identification of individuals in forensic medicine. Forensic Sci Int. 2012 ;219(1-3):e25-8.
2011年
Watanabe K, Ikegaya H, Hirayama K, Motani M, Iwase H, Kaneko H, Fukushima H, Akutsu T, Sakurada K: A Novel Method for ABO Genotyping Using a DNA Chip. J Forensic Sci. 2011; 56(S1):S183-187.
Ishikawa N, Hara J, Takasaka T, Kobayashi M, Yoshimoto K, Ikegaya H: Age estimation using cytochrome c oxidase analysis. Forensic Sci Int. 2011; 209:48-52.
Takasaka T, Itoh Y, Kaneko H, Ikegaya H: Detection of hepatitis C virus and antibodies in postmortem blood and bloodstains. J Clin Microbiol. 2011; 49(3):1122-1123.
Takasaka T, Sakurada K, Akutsu T, Nishigaki K, Ikegaya H: Trials of the detection of semen and vaginal fluid RNA using the genome profiling method. Legal Med. 2011; 13:265-267.
Nishimura K, Inoue T, Yoshimoto K, Taniguchi T, Kitamura Y, Agata K: Regeneration of dopaminergic neurons after 6-hydroxydopamine-induced lesion in planarian brain. J. Neurochem. 2011; 119:1217-1231.
Matsumoto Y, Murakami H, Hattori N, Yoshimoto K, Asano S, Inden M: Excessive expression of hippocampal ezerin is induced by intrastriatal injection of 6-hydroxydopamine. Biol. Pharm. Bull. 2011; 34:1753-1758.
Takasaka T, Ito Y, Kaneko H, Ikegaya H. Detection of hepatitis C virus and antibodies in postmortem blood and bloodstains. J Clin Microbiol.2011;49(3);1122-1123
Inoue H, Motani-Saitoh H, Sakurada K, Ikegaya H, Yajima D, Hayakawa M, Sato Y, Otsuka K,Kobayashi K, Nagasawa S, Iwase H. Detection of varicella-zoster virus DNA in414 human trigeminal ganglia from cadavers by the polymerase chain reaction: acomparison of the detection rate of varicella-zoster virus and herpes simplexvirus type 1. J Med Virol. 2010;82(2):345-349.
Kaneko T, Chiba H, Horie N, Kato T, Kobayashi M,Hashimoto K, Kusama K, Sakagami H. Inhibition of prostaglandin e2 production byflavone and its related compounds. In Vivo. 2010; 24(1): 55-58.
Onuki H, Sakagami H, Kobayashi M, Hibino Y, Yokote Y, Nakajima H, Shimada J. Effect of contact with titanium alloys on theproliferation of mouse osteoblastic cells in culture. In Vivo. 2010; 24(1):29-37.
Kato H, Yoshimoto K, Kobayashi M, Funaki K, Ikegaya H. Oral administration of ethanol with aspirin increases the concentration ofsalicylic acid in plasma and <>organs, especially the brain, in mice. European Journal of Pharmacology. 2010. 635(1-3):184-7.
Kato H, Yoshimoto K, Ikegaya H. Two cases of oral aspirin overdose. Journal of Forensic and Legal Medicine. 2010. 17(5):280-2.
Akutsu T, Ikegaya H, Watanabe K, Fukushima H, Motani H, Iwase H, Sakurada K. Evaluation of Tamm-Horsfall Protein and Uroplakin III for Forensic Identification of Urine. J Forensic Sci. 2010. 55(3):742-6.
Inoue H, Motani-Saitoh H, Sakurada K, Ikegaya H, Yajima D, Hayakawa M, Sato Y, Otsuka K, Kobayashi K, Nagasawa S, Iwase H. Detection of varicella-zoster virus DNA in 414 human trigeminal ganglia from cadavers by the polymerase chain reaction: a comparison of the detection rate of varicella-zoster virus and herpes simplex virus type 1. J Med Virol. 2010 82(2):345-9.
Inoue H, Motani-Saitoh H, Sakurada K, Ikegaya H, Yajima D, Hayakawa M, Sato Y, Otsuka K, Kobayashi K, Nagasawa S, Iwase H. Determination of the geographical origin of unidentified cadavers based on geographical differences in genotype of varicella-zoster virus. J Med Virol. 2010. 82(5):903-8.
Nakamura A, Kadowaki T, Sakakibara SI, Yoshimoto K, Hirata K and Ueda S.: Regeneration of 5-HT fibers in hippocampal heterotopia of methylazoxymethanol-induced micrencephalaic rats after neonatal 5,7-DHT injection. Anat. Sci. Int. 2010. 85: 38-45.
Isoda K, Morimoto M, Matsui F, Hasegawa T, Tozawa T, Morioka S, Chiyonobu T, Nishimura, Yoshimoto K and Hosoi H.: Postnatal changes in serotonergic innervation to the hippocampus of methyl-CpG-binding protein 2-null mice. Neuroscience. 2010.165: 1254-1260.
Matsui F, Morimoto M, Yoshimoto K, Nakatomi Y, Syoji H, Nishimura A, Isoda K, Tanda K and Hosoi H. Effccts of stress of postnatal development on coruticosterone, serotonin and behavioral changes. Brain Dev. 2010. 32(7) 517-522.
Hioki C, Yoshida T, Kogure A, Yoshimoto K and Shimatsu A: Growth hormone administration control body composition associated with changes of thermogenesis in obese KK-Ay mice. The Open Endocrinology Journal. 2010. 4: 3-8.
Nakamura K, Itoho K, Yoshimoto K, Sugimoto T and Fushiki S: Prenatal and lactational exposure to low-doses of bisphenol A alters brain monoamine concentration in adult mice. Neuroscience Letters. 2010. 484: 66-70.
Samejima K, Hiramatsu K, Takahashi K, Kawakita M, Kobayashi M, Tsumoto H, Kohda K.Identification anddetermination of urinary acetylpolyamines in cancer patients by electrosprayionization and time-of-flight massspectrometry.Anal Biochem. 2010. 401(1):22-9.
Onuki H, Sakagami H, Kobayashi M, Hibino Y, Yokote Y, Nakajima H, Shimada J. Effect of contact with titanium alloys on theproliferation of mouse osteoblastic cells in culture. In Vivo. 2010; 24(1):29-37.
Kaneko T, Chiba H, Horie N, Kato T, Kobayashi M, Hashimoto K, Kusama K, Sakagami H. Inhibition of prostaglandin E2 production by flavone and its related compounds. In Vivo. 2010; 24(1): 55-8.
Tanaka M, Watanabe Y, Yoshimoto K. Regulation of relaxin 3 geneexpression via cAMP-PKA in a neuroblastoma cell line.J Neurosci Res. 2009; 87: 820-829.
Yoshimoto K, Hori M, Shinmen N,Kakiuchi K, Kato H, Sakabe M, Ikegaya H. Forensic studies of brainvulnerability and resistance: Ischemia-induced dopamine and serotonin releasesin the rat nucleusaccumbens. Legal Med. 2009; 11:S279-S281.
Narita T, Suga A, Kobayashi M, Hashimoto K,Sakagami H, Motohashi N, Kurihara T, Wakabayashi H. Tumor-specific cytotoxicityand type of cell death induced by benzo[b]cyclohept [e][1,4]oxazine and 2-aminotroponederivatives. Anticancer Res.2009; 29(4): 1123-1130.
Sakagami H, Kishino K, Kobayashi M, Hashimoto K,Iida S, Shimetani A, Nakamura Y, Takahashi K, Ikarashi T, Fukamachi H, Satoh K,Nakashima H, Shimizu T, Takeda K, Watanabe S, Nakamura W. Selective antibacterial andapoptosis-modulating activities of mastic. In Vivo. 2009; 23(2): 215-223.
Kaneko T, Chiba H, Horie N, Kato T, Kobayashi M,Hashimoto K, Kusama K, Sakagami H. Effect of Scutellariae radix ingredients onprostaglandin E(2) production and COX-2 expression by LPS-activated macrophage.In Vivo. 2009; 23(4): 577-581.
Sakurada K, Ikegaya H, Ohta H, Fukushima H, Akutsu T, Watanabe K.Effects of oximes on mitochondrial oxidase activity. Toxicol Lett.2009;189(2):110-114.
Zhong S, Jeong BH, Ikegaya H, Kim YS, Xu Y, Zhu M, Chao Y, Suzuki M,Kitamura T, Homma Y, Yogo Y. Comparison of the distribution patterns of BKpolyomavirus lineages amongChina,KoreaandJapan: implications for human migrations innortheastAsia. Microbiol Immunol.2009;53(5):266-276.
Zhong S, Randhawa PS, Ikegaya H, Chen Q, Zheng HY, Suzuki M,Takeuchi T, Shibuya A, Kitamura T, Yogo Y. Distribution patterns of BKpolyomavirus (BKV) subtypes and subgroups in American, European and Asianpopulations suggest co-migration of BKV and the human race. J Gen Virol.2009;90(Pt 1):144-152.
Ikegaya H, Saukko P,Katsumata Y, Takatori T. Geographical Identification by Viral Genotyping. WileyEncyclopedia of Forensic Science. 2009.AllanJamieson &John Wiley & Sons,Ltd. Columbia City,IN,USA(eds.),DOI:10.1002/9780470061589.fsa464.
Uemura K, Shintani-Ishida K, Saka K, Nakajima M, Ikegaya H, Kikuchi Y, Yoshida KI. Biochemical blood markers and sampling sites in forensic autopsy. J Forensic Leg Med. 2008, 15(5):312-317.
Okuno S, Sakurada K, Ohta H, Ikegaya H, Kazui Y, Akutsu T, Takatori T, Iwadate K. Blood-brain barrier penetration of novel pyridinealdoxime methiodide (PAM)-type oximes examined by brain microdialysis with LC-MS/MS. Toxicol Appl Pharmacol. 2008, 15;227(1):8-15.
Ikegaya H, Motani H, Sakurada K, Sato K, Akutsu T, Yoshino M. Forensic application of Epstein-Barr virus genotype: correlation between viral genotype and geographical area. J Virol Methods. 2008, 147(1):78-85.
Ikegaya H, Zhong S, Shimizu H, Sekiyama M, Soemantri A, Ishida T, Nakazawa M, Ohtsuka R, Takasaka T, Shibuya A, Kitamura T, Yogo Y. The Pacific Lineage (2E) of JC Polyomavirus is Prevalent in Sumba Island, Eastern Indonesia. Anthropol Sci. 116(2): 183-186, 2008.
Ikegaya H, Yajima D, Iwase H. Vertebral Artery Rupture in a Sudden Death Case after Mild Trauma. Am J Forensic Med Pathol. 29(2): 276-278, 2008.
Y. Nakatomi, C. Yokoyama, S. Kinoshita, D. Masaki, H. Tsuchida, H. Onoe, K. Yoshimoto and K. Fukui: Serotonergic mediation of the antidepressant-like of the green leaves odor in mice. Neuroscience Letter 436: 167-170, 2008.
Ikegaya H, Suganami H. Correlation between climate and crime in Eastern Tokyo. Can J Crim Crim Just. 50(2): 225-238, 2008.
Y.Yogo, S. Zhong, Y. Xu, M. Zhu, Y. Chao, C. Sugimoto, H. Ikegaya, A. Shibuya and T. Kitamura. Conserved archetypal configuration of the transcriptional control region during the course of BK polyomavirus evolution. J Gen Virol ; 89: 1849 - 1856, 2008.
2007年
Hirata M, Sakuma K, Okajima S, Fujiwara H, Inashima S, Yasuhara M, Kubo T. Increased expression of neuregulin-1 in differentiating muscle satellite cells and in motoneurons during muscle regeneration. Acta Neuropathol 2007; 113(4): 451-459.
Kato H, Narita M, Suzuki M, Yoshimoto K, Yasuhara M, Suzuki T. Role of tyrosine kinase-dependent phosphorylation of NR2B subunit-containing NMDA receptor in morphine reward. Jpn J Alcohol & Drug Dependence 2007; 42(1): 13-20.