Hirata A, Nakamura R, Kwak S, Nagata N, Kamakura K: AMPA receptor-mediated slow neuronal death in the rat spinal cord induced by long-term blockade of glutamate transporters with THA. Brain Res 71:37-44, 1997.
Nakamura R, Kamakura K, Hirata A, Kwak S: Concentration-dependent changes
in motor behavior produced by continuous intrathecal infusion of excitatory
amino acids in the rat spinal cord, Brain ResProtocols 1:385-390, 1997.
Nagao S, Kwak S, Kanazawa I: EAAT4, a glutamate transporter with properties
of a chloride channel, is predominantly localized in Purkinje cell dendrites,
and forms parasagittal compartments in rat cerebellum. Neuroscience 78:929-933, 1997.
Nishiyama K, Murayama S, Kwak S, Kanazawa I: Expression of the Cu/Zn superoxide dismutase gene in amyotrophic lateral sclerosis. Ann Neurol 41:551-556, 1997.
Nishiyama K, Kwak S, Takekoshi S, Watanabe K, Kanazawa I: In situ nick
end-labeling detects necrosis of hippocampal pyramidal cells induced by
kainic acid. Neurosci Lett 212:139-142, 1996.
Kwak S, Miyamoto M, Ishida M, Shinozaki H: Neurotoxicity of (2S,1'R,2'R,3'R)-2-(2,3-dicarboxycyclopropyl)glycine,
a potent agonist for class II metabotropic glutamate receptors, in the
rat. Neuroscience 73:687-695, 1996.
Kwak S, Nakamura R: Selective degeneration of inhibitory interneurons in the rat spinal cord induced by intrathecal infusion of acromelic acid, Brain Res 702:61-71, 1995.
Nishiyama K, Kwak S, Murayama S, Watanabe M, Goto J, Asayama K, Kanazawa
I: Increased Cu/Zn superoxide dismutase-like immunoreactivity in the swollen
axons of rats intoxicated chronically with b, b'-iminodipropionitrile,
Neurosci Lett 194:205-208, 1995.
Kwak S, Nakamura R: Acute and late neurotoxicity in the rat spinal cord in vivo induced by glutamate receptor agonists. J Neurol Sci 129(Suppl.): 99-103, 1995.
Nishiyama K, Kwak S, Murayama S & Kanazawa I: Substance P is a possible
neurotransmitter in the rat spinothalamic tract. Neurosci Res 21:261-266,
1995.
Nakamura R, Kamakura K, Kwak S: Late-onset selective neuronal damage in
the rat spinal cord induced by continuous intrathecal administration of
AMPA. Brain Res 654:279-285, 1994.
Miyamoto M., Ishida M, Kwak S, Shinozaki H: Agonists for metabotropic glutamate
receptors in the rat delay recovery from halothane anesthesia. Eur J Pharmacol 260:99-102, 1994.
Masaki T, Ishiura S, Sugita H, Kwak S: Multicatalytic proteinase is associated with characteristic oval structures in cortical Lewy bodies - an immunocytochemical study with light and electron microscopy. J Neurol Sci 122:127-134, 1994.
Matsui K, Wada K, Kwak S: Ataxia-ameliorating effects of YM-14673, a potent
analog of thyrotropin releasing hormone, on ataxic mutant mice. Eur J Pharmacol 254:295-297, 1994.
Okazawa H, Nishiyama K, Kamei M, Washizaki K, Murayama S, Kwak S, Kanazawa
I: Trk immunoreactivity at neuronal dendrite and cell body. Biochem Biophys Res Commun 194:683-690, 1993.
Kwak S, Aizawa H, Ishida M, Shinozaki H.: Acromelic acid, a novel kainate analogue, induces long-lasting paraparesis with selective degeneration of interneurons in the rat spinal cord. Exp Neurol 116: 145-155, 1992.
Kwak S, Aizawa H, Ishida M, Shinozaki H: New, potent kainate derivatives:
comparison of their affinity for [3H]kainate and [3H]AMPA binding sites.
Neurosci Lett 139:114-117, 1992.
Aizawa H., Kwak S, Shimizu T. and Mannen T.: Determination of GABAergic
pallidothalamic termination in human brain. J Neurol Sci 105:124-125, 1991.
Aizawa H, Kwak S, Shimizu T, Mannen T, Shibasaki H: A case of adult onset pure pallidal degeneration: II. Analysis of neurotransmitter markers, with special reference to the termination of pallidothalamic tract in human brain. J Neurol Sci 102:83-91, 1991.
Aizawa H, Kwak S, Shimizu T, Goto J, Nakano I, Mannen T, Shibasaki H: A
case of adult onset pure pallidal degeneration: I. Clinical manifestations
and neuropathological observations. J Neurol Sci 102:76-82, 1991.
Kwak S, Aizawa H, Ishida M, Shinozaki H: Systemic administration of acromelic
acid induces selective neuron damage in the rat spinal cord. Life Sci 49: PL-91-96, 1991.
Shinozaki H, Ishida M, Gotoh Y, Kwak S: Specific lesions of rat spinal interneurons induced by systemic administration of acromelic acid, a new potent kainate analogue. Brain Res 503:330-333, 1989.
Kwak S, A. Matus: Denervation induces long-lasting changes in the distribution
of microtubule proteins in hippocampal neurons. J Neurocytology 17:189-195, 1988.
Kanazawa I, Kwak S, Sasaki H, Mizusawa H, Muramoto O, Yoshizawa K, Nukina
N, Kitamura K, Kurisaki H, Sugita K: Studies on Neurotransmitter markers
and neuronal cell density in the cerebellar system in olivopontocerebellar
atrophy and cortical cerebellar atrophy. J Neurol Sci 71:193-208, 1985.
Kwak S, Kanazawa I, Sugita H, Toyokura Y: Tridimensional distribution of
markers of neurotransmitters within the "accumbens area" of normal
human brains. Neuroscience 13: 717-731, 1984.
Kwak S, Nakamura R, Hirata A, Kamakura K, Kanazawa I: Agonist-specific
neuronal damage mediated by non-NMDA receptors in the rat spinal cord.
In Recent Advances in Clinical Neurophysiology: Proceedings of the Xth
International Congress of EMG and Clinical Neurophysiology, Eds. Kimura
J and Shibasaki H, Elsevier Science, Amsterdam, pp 841-846, 1996.
Hirata A, Nakamura R, Kwak S, Kamakura K: Late-onset selective neuronal
damage in the rat spinal cord induced by continuous administration of AMPA
or THA. In Amyotrophic Lateral Sclerosis: Progress and Perspectives in
Basic Research and Clinical Application. Eds. Nakano I and Hirano A, Elsevier
Science, Amsterdam, pp 227-229, 1996.
Nishiyama K, Kwak S, Murayama S, Kanazawa I: Increased Cu/Zn superoxide
dismutase-like immunoreactivity in the swollen axons of rats intoxicated
chronically with b,b'-iminodipropionitrile (IDPN). In Amyotrophic Lateral
Sclerosis:Progress and Perspectives in Basic Research and Clinical Application.
Eds. Nakano I and Hirano A, Elsevier Science, Amsterdam, pp 230-234, 1996.
Kwak S, Ishida M, Kanazawa I, Shinozaki H: Protection of acromelic acid-induced
neuronal death in the rat spinal cord by a mGluR agonist. In Amyotrophic
Lateral Sclerosis: Progress and Perspectives in Basic Research and Clinical
Application. Eds. Nakano I and Hirano A, Elsevier Science, Amsterdam, pp
215-220, 1996.
Shinozaki H, Ishida M, Kwak S, Nakajima T: Use of acromelic acid for production
of rat spinal lesions. In Methods in Neuroscience, Vol. 7: Lesions and
Transplantation, Ed Conn PM, Academic Press, New York, pp 38-57, 1991.
Shinozaki H, Ishida M, Gotoh Y, Kwak S: Acromelic acid as a tool for the
study of specific neurone damages. In Amino Acids, Chemistry, Biology and
Medicine, Eds. Lubec G and Rosenthal GA, ESCOM Science, Leiden, pp 281-293,
1990.
Kwak S, Aizawa H, Ishida M, Gotoh Y, Shinozaki H: Small neurons in the
lower spinal cord are selectively damaged in the spastic rat by acromelic
acid. In Amino Acids: Chemistry, Biology and Medicine, Eds. Lubec G and
Rosenthal GA, ESCOM Science, Leiden 318-326, 1990.
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