脳科学の研究室 金沢大学医学系

〒920-8640 金沢市宝町13-1

金沢大学医学部 脳神経医学教室





      Journal Articles and Reviews   Points in check  
Wang S., Saito K., Kawasaki H. and Holland, M.A., Orchestrated neuronal migration and cortical folding: A computational and experimental study, PLOS Computational Biology, 2022, in press   米国ノートルダム大学との共同研究  
Shinmyo Y., Saito K., Hamabe-Horiike T., Kameya N., Ando A., Kawasaki K., Dinh D. T. A., Sakashita M., Roboon J., Hattori T., Kannon T., Hosomichi K., Slezak M., Holt M. G., Tajima A., Hori O. and Kawasaki H., Localized astrogenesis regulates gyrification of the cerebral cortex, Science Advances, 8, eabi 5209, 2022   神経解剖学分野、革新ゲノム情報学分野、ベルギーの大学との共同研究

Fujishiro T., Honjo M., Kawasaki H. and Aihara M., Visual cortex damage in a ferret model of ocular hypertension, Japanese Journal of Ophthalmology, 66, 205-212, 2022   東京大学眼科との共同研究  

Shinmyo Y., Hamabe-Horiike T., Saito K. and Kawasaki H., Investigation of the mechanisms underlying the development and evolution of the cerebral cortex using gyrencephalic ferrets, Frontiers in Cell and Developmental Biology, 10, 847159, 2022   フェレットを用いた脳研究の総説  

  河崎洋志, フェレットを用いた大脳の形成・進化および疾患病態の解析, 金沢大学十全医学会雑誌, 印刷中   フェレットを用いた脳研究の総説  

Takahashi M., Fukabori R., Kawasaki H., Kobayashi K. and Kawakami K., The distribution of Cdh20 mRNA demarcates somatotopic subregions and subpopulations of spiny projection neurons in the rat dorsolateral striatum, Journal of Comparative Neurology, 529, 3655-3675, 2021   自治医科大学との共同研究  

Sugiyama T., Murao N., Kadowaki H., Takao K., Miyakawa T., Matsushita Y., Katagiri T., Futatsugi A., Shinmyo Y., Kawasaki H., Sakai J., Shiomi K., Nakazato M., Takeda K., Mikoshiba K., Ploegh H. L., Ichijo H. and Nishitoh H., ERAD components Derlin-1 and Derlin-2 are essential for postnatal brain development and motor function, iScience, 24, 102758, 2021   宮崎大学との共同研究  

Yoshimatsu S., Murakami R., Nakajima M., Sato T., Kawasaki H. and Okano H., Establishment of an induced pluripotent stem cell line from a female domestic ferret (Mustela putorius furo) with an X chromosome instability, Stem Cell Research, 53, 102385, 2021   フェレットのiPS細胞の開発

Morita K., Matsumoto N., Saito K., Hamabe-Horiike T., Mizuguchi K., Shinmyo Y. and Kawasaki H., BMP signaling alters aquaporin-4 expression in the mouse cerebral cortex, Scientific Reports, 11, 10540, 2021   医学類6年生が頑張りました!  

Maeyama H., Shinmyo Y. and Kawasaki H., The expression of aristaless-related homeobox in neural progenitors of gyrencephalic carnivore ferrets, Biochemistry and Biophysics Reports, 26, 100970, 2021    

Okada M., Kawagoe Y., Sato Y., Nozumi M., Ishikawa Y., Tamada A., Yamazaki H., Sekino Y., Kanemura Y., Shinmyo Y., Kawasaki H., Kaneko N., Sawamoto K., Fujii Y., Igarashi M., Phosphorylation of GAP-43 T172 is a molecular marker of growing axons in a wide range of mammals including primates, Molecular Brain, 14, 66, 2021   新潟大学との共同研究  

Hamabe-Horiike T., Kawasaki K., Sakashita M., Ishizu C., Yoshizaki T., Harada S., Ogawa-Ochiai K., Shinmyo Y. and Kawasaki H., Glial cell type-specific gene expression in the mouse cerebrum using the piggyBac system and in utero electroporation, Scientific Reports, 11, 4864, 2021    

Matsumoto N., Tanaka S., Horiike T., Shinmyo Y. and Kawasaki H., A discrete subtype of neural progenitor crucial for cortical folding in the gyrencephalic mammalian brain, eLife, 9, e54873, 2020   大脳の進化のメカニズムを明らかにしました
Nature Index で紹介されました
(メディア⑱, ⑲)

Yoshino M., Saito K., Kawasaki K., Horiike T., Shinmyo Y. and Kawasaki H., The origin and development of subcortical U-fibers in gyrencephalic ferrets, Molecular Brain, 13, 37, 2020   発達した脳に特徴的な大脳皮質のU線維を解析しました  

Kalebic N., Langen B., Helppi J., Kawasaki H., Huttner W.B., In vivo targeting of neural progenitor cells in ferret neocortex by in utero electroporation, Journal of Visualized Experiments, 159, e61171, 2020   ドイツMax Planck Instituteとの共同研究  

Kagami K., Ono M., Iizuka T., Matsumoto T., Hosono T., Sekizuka-Kagami N., Shinmyo S., Kawasaki H. (共同責任著者) and Fujiwara H., A novel third mesh-like myometrial layer connects the outer longitudinal and inner circular muscle fibers: a potential stratum to coordinate uterine contraction, Scientific Reports, 10, 8274, 2020,   金沢大学の産婦人科との共同研究

Ye Y., Dinh Duong. T. A., Saito K., Shinmyo Y., Ichikawa Y., Higashide T., Kagami K., Fujiwara H., Sugiyama K. and Kawasaki H., Visualization of the retina in intact eyes of mice and ferrets using a tissue clearing method, Translational Vision Science & Technology, 4, 1, 2020   金沢大学の眼科・産婦人科との共同研究


Fujishiro T., Honjo M., Kawasaki H., Asaoka R., Yamagishi R., Aihara M., Structural changes and astrocyte response of the lateral geniculate nucleus in a ferret model of ocular hypertension, International Journal of Molecular Sciences, 21, 1339, 2020   東京大学の眼科との共同研究  

  河崎洋志, フェレットとマウスを用いた大脳皮質の形成機構と異常疾患病態の解析, 薬学雑誌, 日本薬学会, 141, 349-357, 2021   フェレットの研究総説   

Kalebic N., Gilardi C., Stepien B., Wilsch-Bräuninger M., Long K. R., Namba T., Florio M., Langen B., Lombardot B., Shevchenko A., Kilimann M.W., Kawasaki H., Wimberger P. and Huttner W. B., Neocortical expansion due to increased proliferation of basal progenitors is linked to changes in their morphology, Cell Stem Cell, 24, 535-550, 2019   ドイツMax Planck Instituteとの共同研究  

Kostic M., Paridaen J.T.M.L., Long K., Kalebic N., Langen B., Grübling N., Wimberger P., Kawasaki H., Namba T. and Huttner W.B., YAP activity is necessary and sufficient for basal progenitor abundance and proliferation in the developing neocortex, Cell Reports, 27, 1103-1118, 2019   ドイツMax Planck Instituteとの共同研究  

Dinh Duong T. A., Hoshiba Y., Saito K., Kawasaki K., Ichikawa Y., Matsumoto N., Shinmyo Y. and Kawasaki H., FGF signaling directs the cell fate switch from neurons to astrocytes in the developing mouse cerebral cortex, Journal of Neuroscience, 39, 6081-6094, 2019   ニューロンからアストロサイトへ転換する仕組みを明らかにしました

Saito K., Mizuguchi K., Horiike T., Dinh Duong T. A., Shinmyo Y. and Kawasaki H., Characterization of the inner and outer fiber layers in the developing cerebral cortex of gyrencephalic ferrets, Cerebral Cortex, 29, 4303-4311, 2019   神経線維層の進化パターンを明らかにしました


   Wakamatsu Y., Egawa S., Terashita Y., Kawasaki H., Tamura K. and Suzuki K. Homeobox code model of heterodont tooth in mammals revised, Scientific Reports, 9, 12865, 2019   マウスとフェレットの歯並びの研究

  河崎洋志, フェレットを用いた大脳の脳回形成の分子機構解析, 生化学, 日本生化学会, 90, 683-689, 2018   フェレットの研究総説   

Matsumoto N., Kobayashi N., Uda N., Hirota M. and Kawasaki H., Pathophysiological analyses of leptomeningeal heterotopia using gyrencephalic mammals. Human Molecular Genetics, 27, 985-991, 2018   医学類3-4年生3名もがんばりました


Martineau F. S., Sahu S., Plantier V., Buhler E., Schaller F., Fournier L., Chazal G., Kawasaki H., Represa A., Watrin F. and Manent J.-B. Correct laminar positioning in the neocortex influences proper dendritic and synaptic development, Cerebral Cortex, 28, 2976-2990, 2018   フランス国立保健医学研究機構との共同研究  

Kagami K., Shinmyo Y., Ono M., Kawasaki H. (共同責任著者) and Fujiwara H., Three-dimensional evaluation of murine ovarian follicles using a modified CUBIC tissue clearing method, Reproductive Biology and Endocrinology, 16, 27, 2018   金沢大学産婦人科との共同研究

Mishima R., Shinmyo Y., Kawasaki H. and Ogawa K. Effect of maternal yokukansan treatment on somatosensory map formation in the cerebral cortex of newborn mouse pups, Traditional & Kampo Medicine, 5, 98-105, 2018   金沢大学漢方医学科との共同研究  

Kawasaki H., Molecular investigations of development and diseases of cerebral cortex folding using gyrencephalic mammal ferrets, Biological and Pharmaceutical Bulletin, 41, 1324-1329, 2018   フェレットの脳研究の総説  

Mizuguchi K., Horiike T., Matsumoto N., Ichikawa Y., Shinmyo Y.and Kawasaki H., Distribution and morphological features of microglia in the developing cerebral cortex of gyrencephalic mammals. Neurochemical Research, 43, 1075-1085, 2018   フェレット大脳皮質におけるミクログリアの分布  

  河崎洋志, 感覚, 最新臨床検査学講座「生理学」, 医歯薬出版, 東京, p95-111, 2018    

Shinmyo Y., Terashita Y., Dinh Duong T. A., Horiike T., Kawasumi M., Hosomichi K., Tajima A. and Kawasaki H., Folding of the cerebral cortex requires Cdk5 in upper-layer neurons in gyrencephalic mammals, Cell Reports, 20, 2131-2143, 2017   フェレット大脳皮質での遺伝子ノックアウト法を確立. Cdk5をノックアウトすると脳回の形成が障害されました.Cell Reports誌のホームページ画像に選ばれました    (メディア⑪)

Matsumoto N., Shinmyo Y., Ichikawa Y. and Kawasaki H., Gyrification of the cerebral cortex requires FGF signaling in the mammalian brain. eLife, 6, e29285, 2017   脳回形成にFGFシグナルが重要であることがわかりました. eLife誌のホームページ画像に選ばれました    (メディア⑫)
Yamasaki T., Deki-Arima N., Kaneko A., Miyamura N., Iwatsuki M., Matsuoka M., Fujimori-Tonou N,, Okamoto-Uchida Y., Hirayama J., Marth J. D., Yamanashi Y., Kawasaki H., Yamanaka K., Penninger J. M., Shibata S. and Nishina H., Age-dependent motor dysfunction due to neuron-specific disruption of stress-activated protein kinase MKK7, Scientific Reports, 7, 7348, 2017   東京医科歯科大・仁科 博史先生との共同研究   
Kagami K., Shinmyo Y., Ono M., Kawasaki H.(共同責任著者) and Fujiwara H., Three-dimensional visualization of intrauterine conceptus through the uterine wall by tissue clearing method, Scientific Reports, 7, 5964, 2017   金沢大学産婦人科との共同研究
Matsumoto N., Hoshiba Y., Morita K., Uda N., Hirota M., Minamikawa M., Ebisu H., Shinmyo Y. and Kawasaki H., Pathophysiological analyses of periventricular nodular heterotopia using gyrencephalic mammals, Human Molecular Genetics, 26, 1173-1181, 2017   医学類2年生の4人ががんばってくれた論文です

  Ebisu H., Iwai-Takekoshi L., Fujita-Jimbo E., Momoii T. and Kawasaki H., Foxp2 regulates identities and projection patterns of thalamic nuclei during development,Cerebral Cortex, 27, 3648-3659, 2017   転写因子Foxp2が視床の核構造の形成を制御することを見出した
  Sato C., Iwai-Takekoshi L., Ichikawa Y. and Kawasaki H., Cell type-specific expression of FoxP2 in the ferret and mouse retina, Neuroscience Research, 117, 1-13, 2017   表紙に選ばれました
  Hasegawa H., Hatano M., Sugimoto H., Ito M., Kawasaki H. and Yoshizaki T., The effects of unilateral cochlear ablation on the expression of vesicular glutamate transporter 1 in the lower auditory pathway of neonatal rats, Auris Nasus Larynx, 44, 690-699, 2017   金沢大学耳鼻咽喉科との共同研究論文  
  Kawasaki H., Molecular investigations of development and diseases of the brain of higher mammals using the ferret, Proceedings of the Japan Academy, Series B, 93, 259-269, 2017   フェレットを用いた研究に関する総説  
  Shinmyo Y. and Kawasaki H., CRISPR/Cas9-mediated gene knockout in the mouse brain using in utero electroporation, Current Protocols in Neuroscience, 79, 3.32.1-3.32.11, 2017   CRISPR/Cas9を用いた大脳皮質での遺伝子ノックアウト法  
  Shinmyo Y., Masuda K., Hoshiba Y., Ebisu H. and Kawasaki H., Molecular investigations of the structure and development of the brain of carnivores, in Brain Evolution by Design, Shigeno S., Murakami Y. and Nomura T. eds., Springer Publishers, New York, pp 311-327, 2017   フェレットを用いた研究に関する総説  
  河崎洋志, セロトニン, 脳内環境辞典, メディカルドゥ, 大阪, p60-61, 2017    
  河崎洋志, 一次体性感覚野の形成過程, CLINICAL NEUROSCIENCE, 中外医学社, 東京, 35, 159-162, 2017    

  河崎洋志, フェレットを用いて脳のシワ形成の謎に迫る, academist Journal 研究コラム 2016    
  Ghosh H., Auguadri L., Battaglia S., Simone Thirouin Z., Zemoura K., Messner S., Acuña M. A., Wildner H., Yévenes G. E., Dieter A., Kawasaki H., Hottiger M. O., Zeilhofer H. U., Fritschy J.-M. and Tyagarajan S. K., Several posttranslational modifications act in concert to regulate gephyrin scaffolding and GABAergic transmission, Nature Communications, 2016, 7, 13365   スイスのチューリッヒ大学との共同研究  
  Toda T., Shinmyo Y., Dinh Duong. T. A., Masuda K. and Kawasaki H., An essential role of SVZ progenitors in cortical folding in gyrencephalic mammals, Scientific Reports, 6, 29578, 2016   脳の表面にあるシワ(脳回)ができる仕組みがわかってきました
  Hoshiba Y., Toda T., Ebisu H., Wakimoto M., Yanagi S. and Kawasaki H., Sox11 balances dendritic morphogenesis with neuronal migration in the developing cerebral cortex,Journal of Neuroscience,25, 5775-5784, 2016   大脳皮質の神経細胞の樹状突起の発達を抑制するメカニズムを見い出した
Journal of NeuroscienceでThis week in the JournalおよびJournal Clubに選ばれた
  Shinmyo Y., Tanaka S., Tsunoda S., Hosomichi K., Tajima A. and Kawasaki H., CRISPR/Cas9-mediated gene knockout in the mouse brain using in utero electroporation, Scientific Reports, 6, 20611, 2016   CRISPR/Cas9を用いた大脳皮質での遺伝子ノックアウト方法の報告
  Inoue N., Ikawa Y., Sato A., Yokoi A., Kuroda M., Nomura K., Sakai S., Tajima H., Ikeda H., Ebisu H., Kawasaki H., Yachie A., Immunostaining of sulfatide-storing macrophages in gallbladder of a patient with metachromatic leukodystrophy, Pediatric Neurology, 64, e3-e4, 2016    

  Shinmyo Y., Riyadh M. A., Ahmed G., Naser I. B., Hossain M., Takebayashi H., Kawasaki H., Ohta K. and Tanaka H., Draxin from neocortical neurons controls the guidance of thalamocortical projections into the neocortex, Nature Communications, 6, 10232, 2015   視床と大脳皮質をつなぐ神経回路の形成メカニズムを見い出した  
  Sadakane O., Masamizu Y., Watakabe A., Terada S., Ohtsuka M., Takaji M., Mizukami H., Ozawa K., Kawasaki H., Matsuzaki M. and Yamamori T., Long-term two-photon calcium imaging of neuronal populations with subcellular resolution in adult non-human primates, Cell Reports, 13, 1989-1999, 2015   当研究室で作成したThy1Sプロモータを応用して、マーモセット脳内でまばらな神経細胞のカルシウムイメージング
  Masuda K., Toda T., Shinmyo Y., Ebisu H., Hoshiba Y., Wakimoto M., Ichikawa Y. and Kawasaki H., Pathophysiological analyses of cortical malformation using gyrencephalic mammals, Scientific Reports,  5,15370, 2015   フェレットを用いて脳回異常疾患モデル動物の作成に成功し その病態解析を行った
  Wakimoto M., Sehara K., Ebisu H., Hoshiba Y., Tsunoda S., Ichikawa Y. and Kawasaki H., Classic cadherins mediate selective intracortical circuit formation in the mouse neocortex, Cerebral Cortex, 25,3535-3546, 2015   大脳皮質の局所神経回路の形成に細胞接着因子のカドヘリンが重要であることを見いだした
  Sadakane O., Watakabe A., Ohtsuka M., Takaji M., Sasaki T., Kasai M., Isa T., Kato G., Nabekura J., Mizukami H., Ozawa K., Kawasaki H. and Yamamori T., In vivo two-photon imaging of dendritic spines in marmoset neocortex, eNeuro, 2, e0019-15, 2015   研究室で作成したThy1Sプロモータを応用して、マーモセット脳内でまばらな神経細胞の形態を2光子顕微鏡で解析
  Kawasaki H., Spatio-temporal regulation of the formation of the somatosensory system, Development, Growth & Differentiation, 57, 193-199, 2015    
  Kawasaki H., Genetic manipulation of gyrencephalic carnivores using in utero electroporation, in Electroporation Methods and Neuroscience, Saito T. ed., Springer Publishers, New York, 2015, pp105-113   フェレットを用いた研究に関する総説  
  河崎洋志, 感覚神経系の分子脳科学, 分子脳科学, 三品昌美編 化学同人, 京都, 69-75, 2015    
  河崎洋志, フェレットを用いた高等哺乳動物の脳神経医学研究, 生体の科学, 66, 1-6, 2015   フェレットを用いた研究に関する総説  

  Fujishiro T., Kawasaki H., Aihara M., Saeki T., Yamagishi R., Atarashi T., Mayama C. and Araie M., Establishment of an experimental ferret ocular hypertension model for the analysis of central visual pathway damage, Scientific Reports, 4, 6501, 2014   東京大学医学部眼科との共同研究
  Toda T. and Kawasaki H., The development of suckling behavior of neonatal mice is regulated by birth, Molecular Brain, 2014, 7, 8

  Developmental Cell 2013の続報
  Kawasaki H., Molecular investigations of the brain of higher mammals using gyrencephalic carnivore ferrets, Neuroscience Research, 86, 59-65, 2014    
  河崎洋志, 体性感覚系における神経回路の形成の時空間的な制御機構, ライフサイエンス領域融合レビュー,
http://leading.lifesciencedb.jp/3-e010, 2014
  河崎洋志, フェレットを用いた高等哺乳動物の脳神経解析, 脳神経系の発生・再生の融合的新展開, 井村裕夫, 高橋淳, 河崎洋志編, 診断と治療社, 東京, 146-149, 2014   フェレットを用いた研究に関する総説  

  Toda T., Homma D., Tokuoka H., Hayakawa I., Sugimoto Y., Ichinose H. and Kawasaki H., Birth regulates the initiation of sensory map formation through serotonin signaling, Developmental Cell, 27, 32-46, 2013 出生は単に子供が生まれるだけのプロセスではなく 実は脳回路の形成を制御していることを見出した
AAASのEurekAlert, 米国, 日本, 中国, イギリス, AASJなどのHPや新聞で紹介された
また Featured Articleに選ばれPreviewで紹介された
  Iwai L., Ohashi Y., van der List D., Usrey WM., Miyashita Y. and Kawasaki H., FoxP2 is a parvocellular-specific transcription factor in the visual thalamus of monkeys and ferrets, Cerebral Cortex, 23, 2204-2212, 2013    高等哺乳動物に特徴的なParvo細胞に選択的に発現する遺伝子の同定に成功
  Kawasaki H., Toda T. and Tanno K., In vivo genetic manipulation of cortical progenitors in gyrencephalic carnivores using in utero electroporation, Biology Open, 2, 95-100, 2013
  戸田智久, 河崎洋志, 出生はセロトニンの濃度の低下を介して感覚系神経回路の形成の開始を制御する, ライフサイエンス新着論文レビュー, 2013

  Yamamoto Y., Lee D., Kim Y., Lee B., Seo C., Kawasaki H., Kuroda S. and Tanaka-Yamamoto K., Raf-kinase inhibitory protein is required for cerebellar long-term synaptic depression by mediating PKC-dependent MAPK activation, Journal of Neuroscience, 32, 14254-14264, 2012
  Kawasaki H., Iwai L. and Tanno K., Rapid and efficient genetic manipulation of gyrencephalic carnivores using in utero electroporation, Molecular Brain, 5, 24, 2012
  フェレットと子宮内電気穿孔法とを組み合わせ 高等哺乳動物での遺伝子導入法の確立に成功
Faculty of 1000 recommended.
  Sehara K., Wakimoto M., Ako R. and Kawasaki H., Distinct developmental principles underlie the formation of ipsilateral and contralateral whisker-related axonal patterns of layer 2/3 neurons in the barrel cortex, Neuroscience, 226, 289–304, 2012
  Kawasaki H., Molecular signatures of parallel pathways in the visual thalamus, in Visual Cortex, Harris JM and Scott J. eds., Nova Science Publishers, New York, 2012, p185-193
  Yamasaki T., Kawasaki H. and Nishina H., Diverse roles of JNK and MKK pathways in the brain, Journal of Signal Transduction, 2012, 459265, 2012
  (特許公開)河崎洋志, 「子宮内電気穿孔法を用いた高等哺乳動物への遺伝子導入方法およびこの方法によって得られる遺伝子導入高等哺乳動物」

  Yamasaki T., Kawasaki H.(Co-corresponding author), Arakawa S., Shimizu K., Shimizu S., Reiner O., Okano H., Nishina S., Azuma N., Penninger J. M., Katada T. and Nishina H., Stress-activated protein kinase MKK7 regulates axon elongation in the developing cerebral cortex, Journal of Neuroscience, 31, 16872-16883, 2011
  Ako R., Wakimoto M., Ebisu H., Tanno K., Hira R., Kasai H., Matsuzaki M. and Kawasaki H., Simultaneous visualization of multiple neuronal properties with single-cell resolution in the living rodent brain, Molecular and Cellular Neuroscience, 48, 246-257, 2011
  Sehara K. and Kawasaki H., Neuronal circuits with whisker-related patterns, Molecular Neurobiology, 43, 155-162, 2011.

  Sehara K., Toda T., Iwai L., Wakimoto M., Tanno K., Matsubayashi Y. and Kawasaki H., Whisker-related axonal patterns and plasticity of layer 2/3 neurons in the mouse barrel cortex, Journal of Neuroscience, 30, 3082-3092, 2010
  マウス体性感覚系における新たな局所神経回路を見出し barrel netsと命名しました
科学技術振興機構JSTニュース および千里ライフサイエンス振興財団ニュースで紹介された
  Hayakawa I. and Kawasaki H., Rearrangement of retinogeniculate projection patterns after eye-specific segregation, PLoS One, 5, e11001, 2010
  Iwai L. and Kawasaki H., Molecular development of the lateral geniculate nucleus in the absence of retinal waves during the time of retinal axon eye-specific segregation, Neuroscience, 159, 1326-1337, 2009
  フェレットの視覚系を用いて 外側膝状体(LGN)の分化過程を分子生物学的に解析  
  Toda T. and Kawasaki H., Regulation of the critical period for whisker lesion-induced barrel structural plasticity in the mouse somatosensory cortex, Somatosensory Cortex, Nova Science, 157-171, 2009
  Matsubayashi Y., Iwai L., Toda T., Lu Q.R. and Kawasaki H., Immunostaining for oligodendrocyte-specific galactosphingolipids in fixed brain sections using the cholesterol-selective detergent digitonin. J. Neurosci. Methods, 178, 87-98, 2009
  Toda T. and Kawasaki H., Regulation of the critical period for whisker lesion-induced barrel structural plasticity in the mouse somatosensory cortex, in Somatosensory Cortex, Johnsen N. and Agerskov R. eds., Nova Science Publishers, New York, 2009, p157-171    
  河崎洋志, 視覚系と体性感覚系を用いた神経回路形成メカニズム解析, ブレインサイエンスレビュー2009, 255-272頁, ブレインサイエンス振興財団
  Toda T., Hayakawa I., Matsubayashi Y., Tanaka K., Ikenaka K., Lu Q.R., and Kawasaki H., Termination of lesion-induced plasticity in the mouse barrel cortex in the absence of oligodendrocytes. Molecular and Cellular Neuroscience, 39, 40-49, 2008
  マウスのバレル体性感覚系を用いて ヒゲ傷害の臨界期可塑性を終了させる分子メカニズムを解析  
  (特許公開)河崎洋志, 松林完, 「界面活性剤を使用した組織染色方法」
  Matsubayashi Y., Iwai L., and Kawasaki H., Fluorescent double-labeling with carbocyanine neuronal tracing and immunohistochemistry using a cholesterol-specific detergent digitonin, Journal of Neuroscience Methods, 174, 71-81, 2008
  Ueno M., Matsumura M., Watanabe K., Nakamura T., Osakada F., Takahashi M., Kawasaki H., Kinoshita S., and Sasai Y., Neural conversion of ES cells by an inductive activity on human amniotic membrane matrix. Proc Natl Acad Sci U S A., 103, 9554-9559, 2006
  Kawasaki H., In appreciation of Lawrence C. Katz (1956-2005), Neuroscience Research, 54, 71-72, 2006
  元ボスであるLarry Katzの追悼文  
  Watanabe K., Kamiya D., Nishiyama A., Katayama T., Nozaki S., Kawasaki H., Watanabe Y., Mizuseki K., and Sasai Y., Directed differentiation of telencephalic precursors from embryonic stem cells. Nature Neuroscience, 8, 288-296, 2005
  Takagi Y., Takahashi J., Saiki H., Morizane A., Hayashi T., Kishi Y., Fukuda H., Okamoto Y., Koyanagi M., Ideguchi M., Hayashi H., Imazato T., Kawasaki H., Suemori H., Omachi S., Iida H., Itoh N., Nakatsuji N., Sasai Y., and Hashimoto N., Dopaminergic neurons generated from monkey embryonic stem cells function in a Parkinson primate model., Journal of Clinical Investigation, 115, 102-109, 2005
  Kawasaki H.(corresponding author), Crowley J. C., Livesey F. J., and Katz L. C., Molecular organization of the ferret visual thalamus, Journal of Neuroscience, 24, 9962-9970, 2004
This Week in The Journalに紹介された
  Haruta M., Sasai Y., Kawasaki H., Amemiya K., Ooto S., Kitada M., Suemori H., Nakatsuji N., Ide C., Honda Y., and Takahashi M., In vitro and in vivo characterization of pigment epithelial cells differentiated from primate embryonic stem cells, Investigative Ophthalmology & Visual Science, 45, 1020-1025, 2004
  (特許公開)高橋政代, 笹井芳樹, 河崎洋志, 大音荘太郎, 「水晶体細胞の作成方法 およびこの方法によって得られる水晶体細胞」
  Tada M., Morizane A., Kimura H., Kawasaki H., Ainscough J. F. X., Sasai Y., Nakatsuji N., and Tada T., Pluripotency of reprogrammed somatic genomes in embryonic stem hybrid cells, Developmental Dynamics, 227, 504-510, 2003
  Mizuseki K., Sakamoto T., Watanabe K., Muguruma K., Ikeya M., Nishiyama A., Arakawa A., Suemori H., Nakatsuji N., Kawasaki H., Murakami F., and Sasai. Y., Generation of neural crest-derived peripheral neurons and floor plate cells from mouse and primate embryonic stem cells., Proc Natl Acad Sci U S A., 100, 5828-5833, 2003
  Ooto S., Haruta M., Honda Y., Kawasaki H., Sasai Y., and Takahashi M., Induction of the differentiation of lentoids from primate embryonic stem cells, Investigative Ophthalmology & Visual Science, 44, 2689-2693, 2003
  Kawasaki H., Suemori H., Mizuseki K., Watanabe K., Urano F., Ichinose H., Haruta M., Takahashi M., Yoshikawa K., Nishikawa S.-I., Nakatsuji N. and Sasai Y., Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity., Proc Natl Acad Sci U S A., 99, 1580-1585, 2002
  Kawasaki H, Mizuseki K and Sasai Y, Selective neural induction from ES cells by stromal cell-derived inducing activity and its possible application to parkinsonian therapy., in Embryonic Stem Cells: Methods and Protocols, Turksen, K. ed., Methods in Molecular Biology series vol. 185, Humana Press, Totowa, New Jersey, 2002, p 217-227
  河崎洋志, 再生医科学とParkinson病治療の展望, 神経治療学, 第19巻 1号51-56頁, 日本神経治療学会, 2002年
  河崎洋志, ES細胞から神経細胞への分化制御, 細胞工学, 第20巻7号979-983頁, 秀潤社, 2001年
  Kawasaki, H., Mizuseki, K., Nishikawa, S., Kaneko, S., Kuwana, Y., Nakanishi, S., Nishikawa, S.-I. and Sasai, Y., Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity., Neuron, 28, 31-40, 2000
  マウスES細胞からin vitroでドーパミン神経細胞を分化誘導することに成功
NeuronのMinireview で紹介された
  Kawasaki, H., Fujii, H., Gotoh, Y., Morooka, T., Shimohama, S., Nishida, E. and Hirano, T., Requirement for mitogen-activated protein kinase in cerebellar long term depression, Journal of Biological Chemistry, 274, 13498-13502, 1999
  Kawasaki, H., Morooka, T., Shimohama, S., Kimura, J., Hirano, T., Gotoh, Y. and Nishida, E., Activation and involvement of p38 mitogen-activated protein kinase in glutamate-induced apoptosis in rat cerebellar granule cells, Journal of Biological Chemistry, 272, 18518-18521, 1997
  Kawasaki H, Matsuda S, Fukuda M, and Nishida E, Signaling pathways and function of the MAP kinase superfamily molecules. in Kinases and Phosphatases in Lymphocyte and Neuronal Signaling, Yakura, H. ed., Springer-Verlag press, Tokyo, 1997, p 37-46
  河崎洋志, 後藤由季子, 西田栄介, MAPキナーゼカスケード, 蛋白質核酸酵素増刊号・脳における情報伝達, 424-430頁, 共立出版, 1997年
  河崎洋志, 下濱俊, 西田栄介, 神経系とMAPキナーゼスーパーファミリー, 最新医学, 第52巻, 2447-2451頁, 最新医学社、1997年
  Kawasaki, H., Moriguchi, T., Matsuda, S., Li, H.-Z., Nakamura, S., Shimohama, S., Kimura, J., Gotoh, Y. and Nishida, E., Ras-dependent and Ras-independent activation pathways for the stress-activated-protein-kinase cascade, European Journal of Biochemistry, 241, 315-321, 1996
  Li, H.-Z., Kawasaki, H., Nishida, E., Hattori, S. and Nakamura, S., Ras-regulated hypophosphorylation of the retinoblastoma protein mediates neuronal differentiation in PC12 cells, Journal of Neurochemistry, 66, 2287-2294, 1996
  河崎洋志, 後藤由季子, 西田栄介, MAPキナーゼカスケード, 新臨床医のための分子医学シリーズ・細胞内情報伝達のしくみ, 119-130頁, 羊土社, 1996年
  Matsuda, S., Kawasaki, H. (co-first author), Moriguchi, T., Gotoh, Y. and Nishida, E., Activation of protein kinase cascades by osmotic shock, Journal of Biological Chemistry, 270, 12781-12786, 1995
  Moriguchi, T., Kawasaki, H. (co-first author), Matsuda, S., Gotoh, Y. and Nishida, E., Evidence for multiple activators for stress-activated protein kinases/c-Jun amino-terminal kinases : Existence of novel activators, Journal of Biological Chemistry, 270, 12969-12972, 1995