熊本大学大学院生命科学研究部・薬学教育部　薬物活性学分野

Department of Chemico-Pharmacological Sciences

Graduate School of Pharmaceutical Sciences, Kumamoto University

 

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研究室の業績リスト 2024年10月現在（英文のみ・2007年4月以降）

* IF: 論文公表年時点の掲載誌impact factor（2024年以降の論文については最新[2023]のimpact factor）

 

Nakanishi R, Kurauchi Y, Kotani S, Hitora-Imamura N, Seki T, Katsuki H.

Structurally Distinct Nurr1 Ligands Exhibit Different Pharmacological Characteristics in Regulating Inflammatory Responses of Microglial BV-2 Cells.

Biol Pharm Bull. in press. (IF 1.7)

 

Kurauchi Y, Inoue K, Kawakami T, Ueda M, Yamaguchi T, Akaki J, Komorisono M, Katsuki H.

Analgesic effect of Keishinieppiittokajutsubu on low barometric pressure-induced pain response in arthritic model rats.

J Pharmacol Sci. 2024 Dec;156(4):230-234. (IF 3.0)

 

Motomura K, Ueda E, Boateng A, Sugiura M, Kadoyama K, Hitora-Imamura N, Kurauchi Y, Katsuki H, Seki T.

Identification of a novel aromatic-turmerone analog that activates chaperone-mediated autophagy through the persistent activation of p38.

Front. Cell Dev. Biol. 2024 Aug 8;12:1418296. (IF 4.6)

 

Yamada Y, Ishitsuka Y, Fukaura-Nishizawa M, Kawata T, Ishii A, Shirakawa A, Sakai T, Tanaka M, Kondo Y, Takeo T, Nakagata N, Motoyama K, Higashi T, Arima H, Seki T, Kurauchi Y, Katsuki H, Higaki K, Ikeda R, Matsuo M, Era T, Irie T.

Intracerebroventricular 2-hydroxypropyl-γ-cyclodextrin alleviates hepatic manifestations without distributing to the liver in a murine model of Niemann–Pick disease type C.

Life Sci. 2024 Aug 1;350(7):122776. (IF 5.2)

 

Ushida K, Kinoshita K, Ichihara Y, Hirata Y, Kurauchi Y, Seki T, Katsuki H.

Menaquinone-4 Alleviates Neurological Deficits Associated with Intracerebral Hemorrhage by Preserving Corticospinal Tract in Mice.

Neurochem Res. 2024 Jul;49(7):1838-1850. (IF 3.7)

 

Kinoshita K, Motomura K, Ushida K, Hirata Y, Konno A, Hirai H, Kotani S, Hitora-Imamura N, Kurauchi Y, Seki T, Katsuki H.

Nurr1 overexpression in the primary motor cortex alleviates motor dysfunction induced by intracerebral hemorrhage in the striatum in mice.

Neurotherapeutics. 2024 Jul;21(4):e00370. (IF 5.6)

 

Kurauchi Y, Ryu S, Tanaka R, Haruta M, Sasagawa K, Seki T, Ohta J, Katsuki H.

Goreisan regulates cerebral blood flow according to barometric pressure fluctuations in female C57BL/6J mice.

J Pharmacol Sci. 2024 Feb;154(2):47-51. (IF 3.0)

 

 

2023

Atef Y, Kinoshita K, Ichihara Y, Ushida K, Hirata Y, Kurauchi Y, Seki T, Katsuki H.

Therapeutic effect of allicin in a mouse model of intracerebral hemorrhage.

J Pharmacol Sci. 2023 Dec;153(4):208-214. (IF 3.0)

 

Miyagami Y, Honshuku Y, Nomura H, Minami M, Hitora-Imamura N.

Evaluation of behavioural selection processes in conflict scenarios using a newly developed mouse behavioural paradigm.

Sci Rep. 2023 Nov 16;13(1):20006. (IF 3.8)

 

Nakanishi S, Kinoshita K, Kurauchi Y, Seki T, Kimura Y, Suzuki M, Suzuki K, Koyama H, Kagechika H, Katsuki H.

Acyclic retinoid peretinoin reduces hemorrhage-associated brain injury in vitro and in vivo.

Eur J Pharmacol. 2023 Sep 5;954:175899. (IF 4.2)

 

Yamada Y, Fukaura-Nishizawa M, Nishiyama A, Ishii A, Kawata T, Shirakawa A, Tanaka M, Kondo Y, Takeo T, Nakagata N, Miwa T, Takeda H, Orita Y, Motoyama K, Higashi T, Arima H, Seki T, Kurauchi Y, Katsuki H, Higaki K, Minami K, Yoshikawa N, Ikeda R, Matsuo M, Irie T, Ishitsuka Y.

Different solubilizing ability of cyclodextrin derivatives for cholesterol in Niemann-Pick disease type C treatment.

Clin Transl Med. 2023 Aug;13(8):e1350. (IF 7.9)

 

Idera A, Sharkey LM, Kurauchi Y, Kadoyama K, Paulson HL, Katsuki H, Seki T.

Wild-type and pathogenic forms of ubiquilin 2 differentially modulate components of the autophagy-lysosome pathways.

J Pharmacol Sci. 2023 Jul;152(3):182-192. (IF 3.0)

 

Koyama H, Nakamura N, Kimura Y, Ogata A, Ikenuma H, Ishii H, Zhang MR, Kawamura K, Minamimoto T, Nagai Y, Katsuki H, Kimura T, Kimura N, Ichise M, Kato T, Ito K, Suzuki M.

11C-Labeling of acyclic retinoid peretinoin by rapid C-[11C]methylation to disclose novel brain permeability and central nervous system activities hidden in antitumor agent.

Bioorg Med Chem Lett. 2023 Apr 1;85:129212. (IF 2.5)

 

Kurauchi Y, Ohta Y, Matsuda K, Sanematsu W, Devkota HP, Seki T, Katsuki H.

Matcha Tea Powder's Antidepressant-like Effect through the Activation of the Dopaminergic System in Mice Is Dependent on Social Isolation Stress.

Nutrients. 2023 Jan 22;15(3):581. (IF 4.8)

 

 

2022

Atef Y, Kinoshita K, Ichihara Y, Ushida K, Kurauchi Y, Seki T, Katsuki H.

Distinct Pharmacological Profiles of Monosulfide and Trisulfide in an Experimental Model of Intracerebral Hemorrhage in Mice.

Biol Pharm Bull. 2022 Nov;45(11):1699-1705. (IF 2.0)

 

Maeda H, Ichimizu S, Watanabe H, Hamasaki K, Chikamatsu M, Murata R, Yumoto N, Seki T, Katsuki H, Otagiri M, Maruyama T.

Cell-penetrating albumin enhances the sublingual delivery of antigens through macropinocytosis.

Int J Biol Macromol. 2022 Nov 30;221:1439-1452. (IF 8.2)

 

Yamada Y, Miwa T, Nakashima M, Shirakawa A, Ishii A, Namba N, Kondo Y, Takeo T, Nakagata N, Motoyama K, Higashi T, Arima H, Kurauchi Y, Seki T, Katsuki H, Okada Y, Ichikawa A, Higaki K, Hayashi K, Minami K, Yoshikawa N, Ikeda R, Ishikawa Y, Kajii T, et al.

Fine-tuned cholesterol solubilizer, mono-6-O-α-D-maltosyl-γ-cyclodextrin, ameliorates experimental Niemann-Pick disease type C without hearing loss.

Biomed Pharmacother. 2022 Nov;155:113698. (IF 7.5)

 

Nagaoka K, Kurauchi Y, Asano D, Morita A, Sakamoto K, Nakahara T.

Pharmacological inhibition of Na+/K+-ATPase induces neurovascular degeneration and glial cell alteration in the rat retina.

Exp Eye Res. 2022 Jul;220:109107. (IF 3.4)

 

Kinoshita K, Chung KK, Katsuki H, Arai K.

Therapeutic potential of prophylactic exercise for intracerebral hemorrhage.

Neural Regen Res. 2022 Jul;17(7):1484-1485. Perspective. (IF 6.1)

 

Kinoshita K, Yoshimizu A, Ichihara Y, Ushida K, Kotani S, Kurauchi Y, Seki T, Katsuki H.

A Nurr1 ligand C-DIM12 attenuates brain inflammation and improves functional recovery after intracerebral hemorrhage in mice.

Sci Rep. 2022 Jun 30;12:11009. (IF 4.6)

 

Ueda E, Ohta T, Konno A, Hirai H, Kurauchi Y, Katsuki H, Seki T.

D-Cysteine Activates Chaperone-Mediated Autophagy in Cerebellar Purkinje Cells via the Generation of Hydrogen Sulfide and Nrf2 Activation.

Cells. 2022 Apr 5;11(7):1230. (IF 6.0)

 

Guinto MC, Haruta M, Kurauchi Y, Saigo T, Kurasawa K, Ryu S, Ohta Y, Kawahara M, Takehara H, Tashiro H, Sasagawa K, Katsuki H, Ohta J.

Modular head-mounted cortical imaging device for chronic monitoring of intrinsic signals in mice.

J Biomed Opt. 2022 Feb 14;27(2):026501. (IF 3.5)

 

Yoshimizu A, Kinoshita K, Ichihara Y, Kurauchi Y, Seki T, Katsuki H.

Hydroxychloroquine improves motor function and affords neuroprotection without inhibition of inflammation and autophagy in mice after intracerebral hemorrhage.

J Neuroimmunol. 2022 Jan 15;362:577786. (IF 3.3)

 

 

2021

Devkota HP, Gaire BP, Hori K, Subedi L, Adhikari-Devkota A, Belwal T, Paudel KR, Jha NK, Singh SK, Chellappan DK, Hansbro PM, Dua K, Kurauchi Y.

The science of matcha: Bioactive compounds, analytical techniques and biological properties.

Trends Food Sci Technol. 2021 Dec;118:735-743. Review. (IF 16.002)

 

Ohtomo R, Ishikawa H, Kinoshita K, Chung KK, Hamanaka G, Ohtomo G, Takase H, Wrann CD, Katsuki H, Iwata A, Lok J, Lo EH, Arai K.

Treadmill exercise during cerebral hypoperfusion has only limited effects on cognitive function in middle-aged subcortical ischemic vascular dementia mice.

Front Aging Neurosci. 2021 Dec;13:756537. (IF 5.702)

 

Katsuki H.

Nuclear receptors of NR1 and NR4 subfamilies in the regulation of microglial functions and pathology.

Pharmacol Res Perspect. 2021 Dec;9(6):e00766. Review. (IF 2.963)

 

Matsumoto K, Kinoshita K, Hijioka M, Kurauchi Y, Hisatsune A, Seki T, Masuda T, Ohtsuki S, Katsuki H.

Nicotine promotes angiogenesis in mouse brain after intracerebral hemorrhage.

Neurosci Res. 2021 Sep;170:284-294. (IF 2.904)

 

Yamada Y, Ishitsuka Y, Kondo Y, Nakahara S, Nishiyama A, Takeo T, Nakagata N, Motoyama K, Higashi T, Arima H, Kamei S, Shuto T, Kai H, Hayashino Y, Sugita M, Kikuchi T, Hirata F, Miwa T, Takeda H, Orita Y, Seki T, Ohta T, Kurauchi Y, Katsuki H, Matsuo M, Higaki K, Ohno K, Matsumoto S, Era T, Irie T.

Differential mode of cholesterol inclusion with 2-hydroxypropyl-cyclodextrins impacts safety margin in treating Niemann-Pick disease type C.

Brit J Pharmacol. 2021 Jul;178(13):2727-2746. (IF 9.473)

 

Ohta T, Morikawa Y, Sato M, Konno A, Hirai H, Kurauchi Y, Hisatsune A, Katsuki H, Seki T.

Therapeutic potential of d-cysteine against in vitro and in vivo models of spinocerebellar ataxia.

Exp Neurol. 2021 Jun;19:113791. (IF 5.620)

 

Hori Y, Tsutsumi R, Nasu K, Boateng A, Ashikari Y, Sugiura M, Nakajima M, Kurauchi Y, Hisatsune A, Katsuki H, Seki T.

Aromatic-turmerone analogs protect dopaminergic neurons in midbrain slice cultures through their neuroprotective activities.

Cells. 2021 May 3;10(5):1090. (IF 7.666)

 

Kinoshita K, Hamanaka G, Ohtomo R, Takase H, Chung KK, Lok J, Lo EH, Katsuki H, Arai K.

Mature Adult Mice With Exercise-Preconditioning Show Better Recovery After Intracerebral Hemorrhage.

Stroke. 2021 May;52(5):1861-1865. (IF 10.170)

 

Sato M, Ohta T, Morikawa Y, Konno A, Hirai H, Kurauchi Y, Hisatsune A, Katsuki H, Seki T.

Ataxic phenotype and neurodegeneration are triggered by the impairment of chaperone-mediated autophagy in cerebellar neurons.

Neuropathol Appl Neurobiol. 2021 Feb;47(2):198-209. (IF 6.250)

 

Fukaura M, Ishitsuka Y, Shirakawa S, Ushihama N, Yamada Y, Kondo Y, Takeo T, Nakagata N, Motoyama K, Higashi T, Arima H, Kurauchi Y, Seki T, Katsuki H, Higaki K, Matsuo M, Irie T.

Intracerebroventricular Treatment with 2-Hydroxypropyl-β-Cyclodextrin Decreased Cerebellar and Hepatic Glycoprotein Nonmetastatic Melanoma Protein B (GPNMB) Expression in Niemann-Pick Disease Type C Model Mice.

Int J Mol Sci. 2021 Jan 5;22(1):452. (IF 6.208)

 

 

2020

Kinoshita K, Ohtomo R, Takase H, Hamanaka G, Chung KK, Lok J, Katsuki H, Arai K.

Different responses after intracerebral hemorrhage between young and early middle-aged mice.

Neurosci Lett. 2020 Sep 14;735:135249. (IF 3.046)

 

Hijioka M, Futokoro R, Ohto-Nakanishi T, Nakanishi H, Katsuki H, Kitamura Y.

Microglia-released leukotriene B4 promotes neutrophil infiltration and microglial activation following intracerebral hemorrhage.

Int Immunopharmacol. 2020 Aug;85:106678. (IF 4.932)

 

Sato M, Ueda E, Konno A, Hirai H, Kurauchi Y, Hisatsune A, Katsuki H, Seki T.

Glucocorticoids negatively regulates chaperone mediated autophagy and microautophagy.

Biochem Biophys Res Commun. 2020 Jul 12;528(1):199-205. (IF 3.575)

 

Watanabe H, Bi J, Murata R, Fujimura R, Nishida K, Imafuku T, Nakamura Y, Maeda H, Mukunoki A, Takeo T, Nakagata N, Kurauchi Y, Katsuki H, Tanaka M, Matsushita K, Fukagawa M, Maruyama T.

A synthetic retinoic acid receptor agonist Am80 ameliorates renal fibrosis via inducing the production of alpha-1-acid glycoprotein.

Sci Rep. 2020 Jul 10;10(1):11424. (IF 4.379)

 

Ohtomo R, Kinoshita K, Ohtomo G, Takase H, Hamanaka G, Washida K, Islam MR, Wrann CD, Katsuki H, Iwata A, Lok J, Lo EH, Arai K.

Treadmill Exercise Suppresses Cognitive Decline and Increases White Matter Oligodendrocyte Precursor Cells in a Mouse Model of Prolonged Cerebral Hypoperfusion.

Transl Stroke Res. 2020 Jun;11(3):496-502. (IF 6.829)

 

Matsumoto K, Kinoshita K, Yoshimizu A, Kurauchi Y, Hisatsune A, Seki T, Katsuki H.

Laquinimod and 3,3'-diindolylemethane alleviate neuropathological events and neurological deficits in a mouse model of intracerebral hemorrhage.

J Neuroimmunol. 2020 May 15;342:577195. (IF 3.478)

 

Noda D, Kurauchi Y, Hisatsune A, Seki T, Katsuki H.

Interactions between rat cortico-striatal slice cultures and neutrophil-like HL60 cells under thrombin challenge: Toward elucidation of pathological events in intracerebral hemorrhage.

J Pharmacol Sci. 2020 Mar;142(3):116-123. (IF 3.337)

 

Obayashi H, Nagano Y, Takahashi T, Seki T, Tanaka S, Sakai N, Matsumoto M, Maruyama H.

Histone deacetylase 10 knockout activates chaperone-mediated autophagy and accelerates the decomposition of its substrate.

Biochem Biophys Res Commun. 2020 Feb 26;523(1):246-252. (IF 3.575)

 

 

2019

Shida W, Tateishi H, Tahara Y, Fujita M, Husham Majeed Alsaadi D, Watanabe M, Koga R, Radwan MO, Ciftci HI, Gezici S, Kurauchi Y, Katsuki H, Otsuka M, Sugimura K, Wada M, Sekeroglu N, Watanabe T.

Antileukemic Activity of Twig Components of Caucasian Beech in Turkey.

Molecules. 2019 Oct 25;24(21). pii: E3850. (IF 3.267)

 

Kurauchi Y, Yoshimaru Y, Kajiwara Y, Yamada T, Matsuda K, Hisatsune A, Seki T, Katsuki H.

Na+, K+-ATPase inhibition causes hyperactivity and impulsivity in mice via dopamine D2 receptor-mediated mechanism.

Neurosci Res. 2019 Sep;146:54-64. (IF 2.645)

 

Oshima M, Seki T, Kurauchi Y, Hisatsune A, Katsuki H.

Reciprocal regulation of chaperone-mediated autophagy/microautophagy and exosome release.

Biol Pharm Bull. 2019;42(8):1394-1401. (IF 1.863)

 

Kurauchi Y, Yamada T, Hisatsune A, Seki T, Katsuki H.

Chronic memantine administration prevents ouabain-induced hyperactivity in mice via maintenance of Na+, K+-ATPase activity in the hippocampus.

J Pharmacol Sci. 2019 Jul;140(3):295-299. (IF 2.835)

 

Adhikari-Devkota A, Kurauchi Y, Yamada T, Katsuki H, Watanabe T, Devkota HP.

Anti‐neuroinflammatory activities of extract and polymethoxyflavonoids from immature fruit peels of Citrus ‘Hebesu’.

J Food Biochem. 2019 Jun;43(6):e12813. (IF 1.662)

 

Sato M, Seki T, Konno A, Hirai H, Kurauchi Y, Hisatsune A, Katsuki H.

Rapamycin activates mammalian microautophagy.

J Pharmacol Sci. 2019 Jun;140(2):201-204. (IF 2.835)

 

Ichimizu S, Watanabe H, Maeda H, Hamasaki K, Ikegami K, Chuang VTG, Kinoshita R, Nishida K, Shimizu T, Ishima Y, Ishida T, Seki T, Katsuki H, Futaki S, Otagiri M, Maruyama T.

Cell-penetrating mechanism of intracellular targeting albumin: Contribution of macropinocytosis induction and endosomal escape.

J Control Release. 2019 Jun 28;304:156-163. (IF 7.727)

 

Kinoshita K, Matsumoto K, Kurauchi Y, Hisatsune A, Seki T, Katsuki H.

A Nurr1 agonist amodiaquine attenuates inflammatory events and neurological deficits in a mouse model of intracerebral hemorrhage.

J Neuroimmunol. 2019 May 15;330:48-54. (IF 3.125)

 

Tsutsumi R, Hori Y, Seki T, Kurauchi Y, Sato M, Oshima M, Hisatsune A, Katsuki H.

Involvement of exosomes in dopaminergic neurodegeneration by microglial activation in midbrain slice cultures.

Biochem Biophys Res Commun. 2019 Apr 2;511(2):427-433. (IF 2.985)

 

Haruta M, Kurauchi Y, Ohsawa M, Inami C, Tanaka R, Sugie K, Kimura A, Ohta Y, Noda T, Sasagawa K, Tokuda T, Katsuki H, Ohta J.

Chronic brain blood-flow imaging device for a behavioral experiment using mice.

Biomed Opt Express. 2019 Mar 4;10(4):1557-1566. (IF 3.921)

 

Noma K, Kurauchi Y, Katsuki H, Oyama Y, Akaike N.

Intra-axonal Ca2+ mobilization contributes to triphenyltin-induced facilitation in glycinergic transmission of rat spinal neurons.

Toxicol In Vitro. 2019 Mar;55:11-14. (IF 2.959)

 

Kurauchi Y, Haruta M, Tanaka R, Sasagawa K, Ohta J, Hisatsune A, Seki T, Katsuki H.

Propranolol prevents cerebral blood flow changes and pain-related behaviors in migraine model mice.

Biochem Biophys Res Commun. 2019 Jan 8;508(2):445-450. (IF 2.985)

 

 

2018

Seki T, Sato M, Kibe Y, Ohta T, Oshima M, Konno A, Hirai H, Kurauchi Y, Hisatsune A, Katsuki H.

Lysosomal dysfunction and early glial activation are involved in the pathogenesis of spinocerebellar ataxia type 21 caused by mutant transmembrane protein 240.

Neurobiol Dis. 2018 Dec;120:34-50. (IF 5.160)

 

Yamakawa T, Kurauchi Y, Hisatsune A, Seki T, Katsuki H.

Endogenous nitric oxide inhibits, whereas awakening stimuli increase, the activity of a subset of orexin neurons.

Biol Pharm Bull. 2018;41(12):1859-1865. (IF 1.540)

 

Seki T, Sato M, Konno A, Hirai H, Kurauchi Y, Hisatsune A, Katsuki H.

d-Cysteine promotes dendritic development in primary cultured cerebellar Purkinje cells via hydrogen sulfide production.

Mol Cell Neurosci. 2018 Dec;93:36-47. (IF 2.855)

 

Kurauchi Y, Noma K, Hisatsune A, Seki T, Katsuki H.

Na+, K+-ATPase inhibition induces neuronal cell death in rat hippocampal slice cultures: Association with GLAST and glial cell abnormalities.

J Pharmacol Sci. 2018 Nov;138(3):167-175. (IF 2.439)

 

Nakazono A, Adachi N, Takahashi H, Seki T, Hamada D, Ueyama T, Sakai N, Saito N.

Pharmacological induction of heat shock proteins ameliorates toxicity of mutant PKCγ in spinocerebellar ataxia type 14.

J Biol Chem. 2018 Sep 21;293(38):14758-14774. (IF 4.106)

 

Takahashi S, Hisatsune A, Kurauchi Y, Seki T, Katsuki H.

Polysulfide protects midbrain dopaminergic neurons from MPP+-induced degeneration via enhancement of glutathione biosynthesis.

J Pharmacol Sci. 2018 May;137(1):47-54. (IF 2.439)

 

Miyahara T, Adachi N, Seki T, Hide I, Tanaka S, Saito N, Irifune M, Sakai N.

Propofol induced diverse and subtype-specific translocation of PKC families.

J Pharmacol Sci. 2018 May;137(1):20-29. (IF 2.439)

 

Noma K, Akaike H, Kurauchi Y, Katsuki H, Oyama Y, Akaike N.

Effects of triphenyltin on glycinergic transmission on rat spinal neurons.

Environ Res. 2018 May;163:186-193. (IF 5.026)

 

 

2017

Anan J, Hijioka M, Kurauchi Y, Hisatsune A, Seki T, Katsuki H.

Cortical hemorrhage-associated neurological deficits and tissue damage in mice are ameliorated by therapeutic treatment with nicotine.

J Neurosci Res. 2017 Sep;95(9):1838-1849. (IF 2.662)

 

Fujita I, Nobunaga M, Seki T, Kurauchi Y, Hisatsune A, Katsuki H.

Cystamine-mediated inhibition of protein disulfide isomerase triggers aggregation of misfolded orexin-A in the Golgi apparatus and prevents extracellular secretion of orexin-A.

Biochem Biophys Res Commun. 2017 Jul 22;489(2):164-170. (IF 2.559)

 

Kurauchi Y, Kinoshita R, Mori A, Sakamoto K, Nakahara T, Ishii K.

MEK/ERK- and calcineurin/NFAT-mediated mechanism of cerebral hyperemia and brain injury following NMDA receptor activation.

Biochem Biophys Res Commun. 2017 Jun 24;488(2):329-334. (IF 2.559)

 

Katsuki H, Hijioka M.

Intracerebral hemorrhage as an axonal tract injury disorder with inflammatory reactions.

Biol Pharm Bull. 2017;40(5):564-568. Review. (IF 1.694)

 

Katsuki H.

Brain damage and potential therapeutic interventions: foreword.

Biol Pharm Bull. 2017;40(5):547. Review. (IF 1.694)

 

Kurauchi Y, Mokudai K, Mori A, Sakamoto K, Nakahara T, Morita M, Kamimura A, Ishii K.

l-Citrulline ameliorates cerebral blood flow during cortical spreading depression in rats: Involvement of nitric oxide- and prostanoids-mediated pathway.

J Pharmacol Sci. 2017 Mar;133(3):146-155. (IF 2.575)

 

Hijioka M, Anan J, Ishibashi H, Kurauchi Y, Hisatsune A, Seki T, Koga T, Yokomizo T, Shimizu T, Katsuki H.

Inhibition of leukotriene B4 action mitigates intracerebral hemorrhage-associated pathological events in mice.

J Pharmacol Exp Ther. 2017 Mar;360(3):399-408. (IF 3.706)

 

 

2016

Dulla YA, Kurauchi Y, Hisatsune A, Seki T, Shudo K, Katsuki H.

Regulatory mechanisms of vitamin D3 on production of nitric oxide and pro-inflammatory cytokines in microglial BV-2 cells.

Neurochem Res. 2016 Nov;41(11):2848-2858. (IF 2.581)

 

Takaoka Y, Takahashi M, Kurauchi Y, Hisatsune A, Seki T, Shudo K, Katsuki H.

Retinoic acid receptor agonist Am80 inhibits CXCL2 production from microglial BV-2 cells via attenuation of NF-κB signaling.

Int Immunopharmacol. 2016 Sep;38:367-376. (IF 2.956)

 

Sato M, Seki T, Konno A, Hirai H, Kurauchi Y, Hisatsune A, Katsuki H.

Fluorescent-based evaluation of chaperone-mediated autophagy and microautophagy activities in cultured cells.

Genes to Cells 2016 Aug;21(8):861-873. (IF 1.993)

 

Kurauchi Y, Hisatsune A, Seki T, Katsuki H.

Na+, K+-ATPase dysfunction causes cerebrovascular endothelial cell degeneration in rat prefrontal cortex slice cultures.

Brain Res. 2016 Aug 1;1644:249-257. (IF 2.746)

 

Hijioka M, Anan J, Matsushita H, Ishibashi H, Kurauchi Y, Hisatsune A, Seki T, Katsuki H.

Axonal dysfunction in internal capsule is closely associated with early motor deficits after intracerebral hemorrhage in mice.

Neurosci Res. 2016 May;106:38-46. (IF 2.060)

 

Kamigaki M, Hide I, Yanase Y, Shiraki H, Harada K, Tanaka Y, Seki T, Shirafuji T, Tanaka S, Hide M, Sakai N.

The Toll-like receptor 4-activated neuroprotective microglia subpopulation survives via granulocyte macrophage colony-stimulating factor and JAK2/STAT5 signaling.

Neurochem Int. 2016 Feb;93:82-94. (IF 3.262)

 

Takahashi S, Hisatsune A, Kurauchi Y, Seki T, Katsuki H.

Insulin-like growth factor 1 specifically up-regulates expression of modifier subunit of glutamate-cysteine ligase and enhances glutathione synthesis in SH-SY5Y cells.

Eur J Pharmacol. 2016 Jan 15;771:99-106. (IF 2.896)

 

 

2015

Fujibayashi T, Kurauchi Y, Hisatsune A, Seki T, Shudo K, Katsuki H.

Mitogen-activated protein kinases regulate expression of neuronal nitric oxide synthase and neurite outgrowth via non-classical retinoic acid receptor signaling in human neuroblastoma SH-SY5Y cells.

J Pharmacol Sci. 2015 Oct;129(2):119-126. (IF 2.106)

 

Maeda Y, Motoyama K, Higashi T, Horikoshi Y, Takeo T, Nakagata N, Kurauchi Y, Katsuki H, Ishitsuka Y, Kondo Y, Irie T, Furuya H, Era T, Arima H.

Effects of cyclodextrins on GM1-gangliosides in fibroblasts from GM1-gangliosidosis patients.

J Pharm Pharmacol. 2015 Aug;67(8):1133-1142. (IF 2.363)

 

Kiyofuji K, Kurauchi Y, Hisatsune A, Seki T, Mishima S, Katsuki H.

A natural compound macelignan protects midbrain dopaminergic neurons from inflammatory degeneration via microglial arginase-1 expression.

Eur J Pharmacol. 2015 Aug;137:63-70. (IF 2.730)

 

Sakamoto K, Mizuta A, Fujimura K, Kurauchi Y, Mori A, Nakahara T, Ishii K.

High-mobility group Box-1 is involved in NMDA-induced retinal injury the in rat retina.

Exp Eye Res. 2015 Aug 5;760:129-135. (IF 2.998)

 

Sakamoto K, Endo K, Suzuki T, Fujimura K, Kurauchi Y, Mori A, Nakahara T, Ishii K.

P2X7 receptor antagonists protect against N-methyl-D-aspartic acid-induced neuronal injury in the rat retina.

Eur J Pharmacol. 2015 Jun 5;756:52-58. (IF 2.730)

 

Asami Y, Nakahara T, Asano D, Kurauchi Y, Mori A, Sakamoto K, Ishii K.

Age-dependent changes in the severity of capillary degeneration in rat retina following N-methyl-D-aspartate-induced neurotoxicity.

Curr Eye Res. 2015 May;40(5):549-553. (IF 2.025)

 

Ramani B, Harris GM, Huang R, Seki T, Murphy GG, Costa Mdo C, Fischer S, Saunders TL, Xia G, McEachin RC, Paulson HL.

A knockin mouse model of spinocerebellar ataxia type 3 exhibits prominent aggregate pathology and aberrant splicing of the disease gene transcript.

Hum Mol Genet. 2015 Mar 1;24(5):1211-1224. (IF 5.985)

 

Takahashi H, Adachi N, Shirafuji T, Danno S, Ueyama T, Vendruscolo M, Shuvaev AN, Sugimoto T, Seki T, Hamada D, Irie K, Hirai H, Sakai N, Saito N.

Identification and characterization of PKCγ, a kinase associated with SCA14, as an amyloidogenic protein.

Hum Mol Genet. 2015 Jan 15;24(2):525-539. (IF 5.985)

 

 

2014

Nobunaga M, Obukuro K, Kurauchi Y, Hisatsune A, Seki T, Tsutsui M, Katsuki H.

High fat diet induces specific pathological changes in hypothalamic orexin neurons in mice.

Neurochem Int. 2014 Dec;78:61-66. (IF 3.092)

 

Morita A, Nakahara T, Abe N, Kurauchi Y, Mori A, Sakamoto K, Nagamitsu T, Ishii K.

Treatment of mid-pregnant mice with KRN633, an inhibitor of vascular endothelial growth factor receptor tyrosine kinase, induces abnormal retinal vascular patterning in their newborn pups.

Birth Defects Res B Dev Reprod Toxicol. 2014 Aug;101(4):293-299. (IF 0.768)

 

Tanaka S, Miyagi T, Dohi E, Seki T, Hide I, Sotomaru Y, Saeki Y, Antonio Chiocca E, Matsumoto M, Sakai N.

Developmental expression of GPR3 in rodent cerebellar granule neurons is associated with cell survival and protects neurons from various apoptotic stimuli.

Neurobiol Dis. 2014 Aug;68:215-227. (IF 5.078)

 

Matsushita H, Hijioka M, Ishibashi H, Anan J, Kurauchi Y, Hisatsune A, Seki T, Shudo K, Katsuki H.

Suppression of CXCL2 upregulation underlies the therapeutic effect of the retinoid Am80 on intracerebral hemorrhage in mice.

J Neurosci Res. 2014 Aug;92(8):1024-1034. (IF 2.594)

 

Sakamoto Y, Hisatsune A, Katsuki H, Horie I, Isohama Y.

Aquaporin 5 increases keratinocyte-derived chemokine expression and NF-κB activity through ERK activation.

Biochem Biophys Res Commun. 2014 Jun 13;448(4):355-360. (IF 2.297)

 

Ichikawa A, Nakahara T, Kurauchi Y, Mori A, Sakamoto K, Ishii K.

Rapamycin prevents N-methyl-D-aspartate-induced retinal damage through an ERK-dependent mechanism in rats.

J Neurosci Res. 2014 Jun;92(6):692-702. (IF 2.594)

 

Yamamoto K, Seki T, Yamamoto H, Adachi N, Tanaka S, Hide I, Saito N, Sakai N.

Deregulation of the actin cytoskeleton and macropinocytosis in response to phorbol ester by the mutant protein kinase C gamma that causes spinocerebellar ataxia type 14.

Front Physiol. 2014 Apr 1;5:126. (IF 3.534)

 

Morita A, Nakahara T, Abe N, Kurauchi Y, Mori A, Sakamoto K, Nagamitsu T, Ishii K.

Effects of pre- and post-natal treatment with KRN633, an inhibitor of vascular endothelial growth factor receptor tyrosine kinase, on retinal vascular development and patterning in mice.

Exp Eye Res. 2014 Mar;120:127-137. (IF 2.709)

 

Sakamoto K, Suzuki Y, Kurauchi Y, Mori A, Nakahara T, Ishii K.

Hydrogen sulfide attenuates NMDA-induced neuronal injury via its anti-oxidative activity in the rat retina.

Exp Eye Res. 2014 Mar;120:90-96. (IF 2.709)

 

Aoki M, Kurauchi Y, Mori A, Nakahara T, Sakamoto K, Ishii K.

Comparison of the effects of single doses of elcatonin and pregabalin on oxaliplatin-induced cold and mechanical allodynia in rats.

Biol Pharm Bull. 2014;37(2):322-326. (IF 1.828)

 

 

2013

Naruoka T, Nakahara T, Tsuda Y, Kurauchi Y, Mori A, Sakamoto K, Nishihira J, Ishii K.

ISO-1, a macrophage migration inhibitory factor antagonist, prevents N-methyl-D-aspartate-induced retinal damage.

Eur J Pharmacol. 2013 Oct 15;718(1-3):138-144. (IF 2.684)

 

Ogawa K, Seki T, Onji T, Adachi N, Tanaka S, Hide I, Saito N, Sakai N.

Mutant γPKC that causes spinocerebellar ataxia type 14 upregulates Hsp70, which protects cells from the mutant's cytotoxicity.

Biochem Biophys Res Commun. 2013 Oct 11;440(1):25-30. (IF 2.281)

 

Obukuro K, Nobunaga M, Takigawa M, Morioka H, Hisatsune A, Isohama Y, Shimokawa H, Tsutsui M, Katsuki H.

Nitric oxide mediates selective degeneration of hypothalamic orexin neurons through dysfunction of protein disulfide isomerase.

J Neurosci. 2013 Jul 31;33(31):12557-12568. (IF 6.747)

※掲載号のFeatured Articleに選定されました（詳しくはこちら）

※熊本日日新聞 2013年8月2日朝刊で紹介されました（プレスリリースの内容はこちら）

 

Matsushita H, Hijioka M, Hisatsune A, Isohama Y, Iwamoto S, Terasawa H, Katsuki H.

MRI-based analysis of intracerebral hemorrhage in mice reveals relationship between hematoma expansion and the severity of symptoms.

PLoS One. 2013 Jul 2;8(7):e67691. (IF 3.534)

※熊本日日新聞 2013年8月14日朝刊で紹介されました

 

Munakata M, Shirakawa H, Nagayasu K, Miyanohara J, Miyake T, Nakagawa T, Katsuki H, Kaneko S.

Transient receptor potential canonical 3 inhibitor pyr3 improves outcomes and attenuates astrogliosis after intracerebral hemorrhage in mice.

Stroke. 2013 Jul;44(7):1981-1987. (IF 6.018)

 

Fujiwara M, Yamamoto H, Miyagi T, Seki T, Tanaka S, Hide I, Sakai N.

Effects of the chemical chaperone 4-phenylbutylate on the function of the serotonin transporter (SERT) expressed in COS-7 cells.

J Pharmacol Sci. 2013 Jun 20;122(2):71-83. (IF 2.114)

 

Seki T, Gong L, Williams AJ, Sakai N, Todi SV, Paulson HL.

JosD1, a membrane-targeted deubiquitinating enzyme, is activated by ubiquitination and regulates membrane dynamics, cell motility and endocytosis.

J Biol Chem. 2013 Jun 14;288(24):17145-17155. (IF 4.600)

 

Tanaka K, Ishitsuka Y, Kurauchi Y, Yamaguchi K, Kadowaki D, Irikura M, Katsuki H, Irie T.

Comparative effects of respiratory stimulants on hypoxic neuronal cell injury in SH-SY5Y cells and in hippocampal slice cultures from rat pups.

Pediatr Int. 2013 Jun;55(3):320-327. (IF 0.731)

 

Kurauchi Y, Hisatsune A, Isohama Y, Sawa T, Akaike T, Katsuki H.

Nitric oxide/soluble guanylyl cyclase signaling mediates depolarization-induced protection of rat mesencephalic dopaminergic neurons from MPP(+) cytotoxicity.

Neuroscience. 2013 Feb 12;231:206-215. (IF 3.327)

 

Noguchi N, Kondo Y, Maeda N, Higa-Nakamine S, Toku S, Maruyama J, Isohama Y, Kukita I, Sugahara K, Yamamoto H.

Phosphorylation of epidermal growth factor receptor at serine 1047 by MAP kinase-activated protein kinase-2 in cultured lung epithelial cells treated with flagellin.

Arch Biochem Biophys. 2013 Jan 15;529(2):75-85. (IF 3.043)

 

 

2012

Kondo Y, Higa-Nakamine S, Noguchi N, Maeda N, Toku S, Isohama Y, Sugahara K, Kukita I, Yamamoto H.

Induction of epithelial-mesenchymal transition by flagellin in cultured lung epithelial cells.

Am J Physiol Lung Cell Mol Physiol. 2012 Dec;303(12):L1057-L1069. (IF 3.523)

 

Hijioka M, Matsushita H, Ishibashi H, Hisatsune A, Isohama Y, Katsuki H.

α7 Nicotinic acetylcholine receptor agonist attenuates neuropathological changes associated with intracerebral hemorrhage in mice.

Neuroscience. 2012 Oct 11;222:10-19. (IF 3.122)

 

Fukasawa H, Nakagomi M, Yamagata N, Katsuki H, Kawahara K, Kitaoka K, Miki T, Shudo K.

Tamibarotene: a candidate retinoid drug for Alzheimer's disease.

Biol Pharm Bull. 2012;35(8):1206-1212. Review. (IF 1.849)

 

Katsuki H, Michinaga S.

Anti-Parkinson drugs and orexin neurons.

Vitam Horm. 2012;89:279-290. Review.

 

Kurauchi Y, Hisatsune A, Isohama Y, Mishima S, Katsuki H.

Caffeic acid phenethyl ester protects nigral dopaminergic neurons via dual mechanisms involving haem oxygenase-1 and brain-derived neurotrophic factor.

Br J Pharmacol. 2012 Jun;166(3):1151-1168. (IF 5.067)

 

Matsushita H, Hijioka M, Hisatsune A, Isohama Y, Shudo K, Katsuki H.

Natural and synthetic retinoids afford therapeutic effects on intracerebral hemorrhage in mice.

Eur J Pharmacol. 2012 May 15;683(1-3):125-131. (IF 2.592)

 

 

2011

Ohnishi M, Katsuki H, Fukutomi C, Takahashi M, Motomura M, Fukunaga M, Matsuoka Y, Isohama Y, Izumi Y, Kume T, Inoue A, Akaike A.

HMGB1 inhibitor glycyrrhizin attenuates intracerebral hemorrhage-induced injury in rats.

Neuropharmacology. 2011 Oct-Nov;61(5-6):975-980. (IF 4.814)

 

Michinaga S, Hisatsune A, Isohama Y, Katsuki H.

Orexin neurons in hypothalamic slice cultures are vulnerable to endoplasmic reticulum stress.

Neuroscience. 2011 Sep 8;190:289-300. (IF 3.380)

 

Hijioka M, Matsushita H, Hisatsune A, Isohama Y, Katsuki H.

Therapeutic effect of nicotine in a mouse model of intracerebral hemorrhage.

J Pharmacol Exp Ther. 2011 Sep;338(3):741-749. (IF 3.828)

 

Hisatsune A, Nakayama H, Kawasaki M, Horie I, Miyata T, Isohama Y, Kim KC, Katsuki H.

Anti MUC1 antibody inhibits EGF receptor signaling in cancer cells.

Biochem Biophys Res Commun. 2011 Feb 18;405(3):377-381. (IF 2.484)

 

Kurauchi Y, Hisatsune A, Isohama Y, Sawa T, Akaike T, Shudo K, Katsuki H.

Midbrain dopaminergic neurons utilize nitric oxide/cyclic GMP signaling to recruit ERK that links retinoic acid receptor stimulation to up-regulation of BDNF.

J Neurochem. 2011 Feb;116(3):323-333. (IF 4.061)

 

Mizutani A, Maeda N, Toku S, Higa-Nakamine S, Isohama Y, Sunakawa H, Sugahara K, Yamamoto H.

Interaction of ethyl pyruvate in vitro with NF-κB subunits, RelA and p50.

Eur J Pharmacol. 2011 Jan 10;650(1):151-156. (IF 2.516)

 

Matsushita H, Hijioka M, Hisatsune A, Isohama Y, Shudo K, Katsuki H.

A retinoic acid receptor agonist Am80 rescues neurons, attenuates inflammatory reactions, and improves behavioral recovery after intracerebral hemorrhage in mice.

J Cereb Blood Flow Metab. 2011 Jan;31(1):222-234. (IF 5.008)

 

 

2010

Katsuki H.

Exploring neuroprotective drug therapies for intracerebral hemorrhage.

J Pharmacol Sci. 2010;114(4):366-378. Review. (IF 2.260)

 

Michinaga S, Hisatsune A, Isohama Y, Katsuki H.

An anti-Parkinson drug ropinirole depletes orexin from rat hypothalamic slice culture.

Neurosci Res. 2010 Dec;68(4):315-321. (IF 2.096)

 

Namba T, Tanaka KI, Ito Y, Hoshino T, Matoyama M, Yamakawa N, Isohama Y, Azuma A, Mizushima T.

Induction of EMT-like phenotypes by an active metabolite of leflunomide and its contribution to pulmonary fibrosis.

Cell Death Differ. 2010 Dec;17(12):1882-1895. (IF 9.050)

 

Obukuro K, Takigawa M, Hisatsune A, Isohama Y, Katsuki H.

Quinolinate induces selective loss of melanin-concentrating hormone neurons, rather than orexin neurons, in the hypothalamus of mice and young rats.

Neuroscience. 2010 Sep 29;170(1):298-307. (IF 3.215)

 

Ohnishi M, Katsuki H, Unemura K, Izumi Y, Kume T, Takada-Takatori Y, Akaike A.

Heme oxygenase-1 contributes to pathology associated with thrombin-induced striatal and cortical injury in organotypic slice culture.

Brain Res. 2010 Aug 6;1347:170-178. (IF 2.623)

 

Ohnishi M, Katsuki H, Izumi Y, Kume T, Takada-Takatori Y, Akaike A.

Mitogen-activated protein kinases support survival of activated microglia that mediate thrombin-induced striatal injury in organotypic slice culture.

J Neurosci Res. 2010 Aug 1;88(10):2155-2164. (IF 2.958)

 

Mizutani A, Maeda N, Toku S, Isohama Y, Sugahara K, Yamamoto H.

Inhibition by ethyl pyruvate of the nuclear translocation of nuclear factor-kappaB in cultured lung epithelial cells.

Pulm Pharmacol Ther. 2010 Aug;23(4):308-15. (IF 2.093)

 

Katsuki H, Kurosu S, Michinaga S, Hisatsune A, Isohama Y, Izumi Y, Kume T, Akaike A.

Depolarizing stimuli cause persistent and selective loss of orexin in rat hypothalamic slice culture.

Peptides. 2010 Jun;31(6):1131-1138. (IF 2.654)

 

Nishimoto Y, Hisatsune A, Katsuki H, Miyata T, Yokomizo K, Isohama Y.

Glycyrrhizin attenuates mucus production by inhibition of MUC5AC mRNA expression in vivo and in vitro.

J Pharmacol Sci. 2010;113(1):76-83. (IF 2.260)

 

Michinaga S, Hisatsune A, Isohama Y, Katsuki H.

Inhibition of neural activity depletes orexin from rat hypothalamic slice culture.

J Neurosci Res. 2010 Jan;88(1):214-221. (IF 2.958)

 

 

2009

Ishitsuka Y, Moriuchi H, Isohama Y, Tokunaga H, Hatamoto K, Kurita S, Irikura M, Iyama K, Irie T.

A selective thromboxane A2 (TXA2) synthase inhibitor, ozagrel, attenuates lung injury and decreases monocyte chemoattractant protein-1 and interleukin-8 mRNA expression in oleic acid-induced lung injury in guinea pigs.

J Pharmacol Sci. 2009 Oct;111(2):211-5. (IF 2.176)

 

Hisatsune A, Kawasaki M, Nakayama H, Mikami Y, Miyata T, Isohama Y, Katsuki H, Kim KC.

Internalization of MUC1 by anti-MUC1 antibody from cell membrane through the macropinocytotic pathway.

Biochem Biophys Res Commun. 2009 Oct 30;388(4):677-682. (IF 2.548)

 

Horie I, Maeda M, Yokoyama S, Hisatsune A, Katsuki H, Miyata T, Isohama Y.

Tumor necrosis factor-a decreases aquaporin-3 expression in DJM-1 keratinocytes.

Biochem Biophys Res Commun. 2009 Sep 25;387(3):564-568. (IF 2.548)

 

Hama Y, Katsuki H, Izumi Y, Kume T, Akaike A.

Excitotoxicity-associated p53 expression in adult rat retina is mediated by calpain activity but not by Cl- influx.

J Pharmacol Sci. 2009 Aug;110(4):493-496. (IF 2.176)

 

Izumi Y, Yamamoto N, Matsuo T, Wakita S, Takeuchi H, Kume T, Katsuki H, Sawada H, Akaike A.

Vulnerability to glutamate toxicity of dopaminergic neurons is dependent on endogenous dopamine and MAPK activation.

J Neurochem. 2009 Jul;110(2):745-755. (IF 3.999)

 

Katsuki H, Kurimoto E, Takemori S, Kurauchi Y, Hisatsune A, Isohama Y, Izumi Y, Kume T, Shudo K, Akaike A.

Retinoic acid receptor stimulation protects midbrain dopaminergic neurons from inflammatory degeneration via BDNF-mediated signaling.

J Neurochem. 2009 Jul;110(2):707-718. (IF 3.999)

 

Jin S, Zhao G, Li Z, Nishimoto Y, Isohama Y, Shen J, Ito T, Takeya M, Araki K, He P, Yamamura K.

Age-related pulmonary emphysema in mice lacking alpha/beta hydrolase domain containing 2 gene.

Biochem Biophys Res Commun. 2009 Mar 6;380(2):419-24. (IF 2.548)

 

Mikami Y, Hisatsune A, Tashiro T, Isohama Y, Katsuki H.

Hypoxia enhances MUC1 expression in a lung adenocarcinoma cell line.

Biochem Biophys Res Commun. 2009 Feb 20;379(4):1060-1065. (IF 2.548)

 

Kuroiwa A, Hisatsune A, Isohama Y, Katsuki H.

Bacterial neuraminidase increases IL-8 production in lung epithelial cells via NF-kB-dependent pathway.

Biochem Biophys Res Commun. 2009 Feb 13;379(3):754-759. (IF 2.548)

 

Kume T, Ito R, Taguchi R, Izumi Y, Katsuki H, Niidome T, Takada-Takatori Y, Sugimoto H, Akaike A.

Serofendic acid promotes stellation induced by cAMP and cGMP analogs in cultured cortical astrocytes.

J Pharmacol Sci. 2009 Jan;109(1):110-118. (IF 2.176)

 

Kurauchi Y, Hisatsune A, Isohama Y, Katsuki H.

Nitric oxide-cyclic GMP signaling pathway limits inflammatory degeneration of midbrain dopaminergic neurons: cell type-specific regulation of heme oxygenase-1 expression.

Neuroscience. 2009 Jan 23;158(2):856-866. (IF 3.292)

 

Ohnishi M, Katsuki H, Takagi M, Kume T, Akaike A.

Long-term treatment with nicotine suppresses neurotoxicity of, and microglial activation by, thrombin in cortico-striatal slice cultures.

Eur J Pharmacol. 2009 Jan 14;602(2-3):288-293. (IF 2.585)

 

 

2008

Kume T, Kawato Y, Osakada F, Izumi Y, Katsuki H, Nakagawa T, Kaneko S, Niidome T, Takada-Takatori Y, Akaike A.

Dibutyryl cyclic AMP induces differentiation of human neuroblastoma SH-SY5Y cells into a noradrenergic phenotype.

Neurosci Lett. 2008 Oct 10;443(3):199-203. (IF 2.200)

 

Hama Y, Katsuki H, Suminaka C, Kume T, Akaike A.

Chloride-dependent acute excitotoxicity in adult rat retinal ganglion cells.

Neuropharmacology. 2008 Oct;55(5):677-686. (IF 3.383)

 

Suzuki KM, Isohama Y, Maruyama H, Yamada Y, Narita Y, Ohta S, Araki Y, Miyata T, Mishima S.

Estrogenic activities of Fatty acids and a sterol isolated from royal jelly.

Evid Based Complement Alternat Med. 2008 Sep;5(3):295-302.

 

Nakamura T, Kume T, Katsuki H, Niidome T, Sugimoto H, Akaike A.

Protective effect of serofendic acid on ischemic injury induced by occlusion of the middle cerebral artery in rats.

Eur J Pharmacol. 2008 May 31;586(1-3):151-155. (IF 2.787)

 

Takei H, Baba Y, Hisatsune A, Katsuki H, Miyata T, Yokomizo K, Isohama Y.

Glycyrrhizin inhibits interleukin-8 production and nuclear factor-kB activity in lung epithelial cells, but not through glucocorticoid receptors.

J Pharmacol Sci. 2008 Mar;106(3):460-468. (IF 2.599)

 

Izumi Y, Yamamoto N, Kume T, Katsuki H, Sawada H, Akaike A.

Regulation of intracellular dopamine levels by dopaminergic drugs: involvement of vesicular monoamine transporter.

Eur J Pharmacol. 2008 Mar 17;582(1-3):52-61. (IF 2.787)

 

Fujimoto S, Katsuki H, Ohnishi M, Takagi M, Kume T, Akaike A.

Plasminogen potentiates thrombin cytotoxicity and contributes to pathology of intracerebral hemorrhage in rats.

J Cereb Blood Flow Metab. 2008 Mar;28(3):506-515. (IF 5.741)

 

 

2007

Kuwahara I, Lillehoj EP, Koga T, Isohama Y, Miyata T, Kim KC.

The signaling pathway involved in neutrophil elastase stimulated MUC1 transcription.

Am J Respir Cell Mol Biol. 2007 Dec;37(6):691-8. (IF 4.608)

 

Koga T, Kuwahara I, Lillehoj EP, Lu W, Miyata T, Isohama Y, Kim KC.

TNF-alpha induces MUC1 gene transcription in lung epithelial cells: its signaling pathway and biological implication.

Am J Physiol Lung Cell Mol Physiol. 2007 Sep;293(3):L693-701. (IF 4.214)

 

Katsuki H, Watanabe Y, Fujimoto S, Kume T, Akaike A.

Contribution of endogenous glycine and d-serine to excitotoxic and ischemic cell death in rat cerebrocortical slice cultures.

Life Sci. 2007 Aug 9;81(9):740-749. (IF 2.257)

 

Oda T, Kume T, Katsuki H, Niidome T, Sugimoto H, Akaike A.

Donepezil potentiates nerve growth factor-induced neurite outgrowth in PC12 cells.

J Pharmacol Sci. 2007 Aug;104(4):349-354. (IF 2.408)

 

Ohnishi M, Katsuki H, Fujimoto S, Takagi M, Kume T, Akaike A.

Involvement of thrombin and mitogen-activated protein kinase pathways in hemorrhagic brain injury.

Exp Neurol. 2007 Jul;206(1):43-52. (IF 3.982)