研究業績 of Ando Lab

[2013]

K. Yamamoto and J. Ando. Endothelial cell and model membranes respond to shear stress by rapidly decreasing the order of their lipid phases. J. Cell Sci. 126:1227-1234, 2013

J. Ando and　K. Yamamoto. Flow detection and calcium signaling in vascular endothelial cells. Cardiovasc. Res. 99:260-268, 2013

[2012]

S. Obi, H. Masuda,T. Shizuno, A. Sato, K. Yamamoto, J. Ando, Y. Abe, T. Asahara. Fluid shear stress induces differentiation of circulating phenotype endothelial progenitor cells. Am. J. Physiol. Cell Physiol. 303: C595-606, 2012 (Selected for Editor’s Picks)

Y. Suzuki, K. Yamamoto, J. Ando, K. Matsumoto, T. Matsuda. Arterial shear stress augments the differentiation of endothelial progenitor cells adhered to VEGF-bound surfaces. Biochem. Biophys. Res. Commun. 423: 91-97, 2012

K. Yamamoto and J. Ando, “Endothelial mechanotransduction and its role in the control of vascular functions” in Shu Chien and Shi Yongde (eds.), Recent Advances in Mechanobiology, Shanghai Science and Technological Literature Publishing House, Shanghai, pp 175-179, 2012

[2011]

K. Yamamoto, K. Furuya, M. Nakamura, E. Kobatake, M. Sokabe, and J. Ando. Visualization of flow-induced ATP release and triggering of Ca2+ waves at caveolae in vascular endothelial cells. J. Cell Sci. 124: 3477-3483, 2011 (Selected for In This Issue)

K. Yamamoto and J. Ando. New molecular mechanisms for cardiovascular disease: Blood flow sensing mechanism in vascular endothelial cells. J. Pharmacol. Sci. 116: 323-331, 2011

A. Ishibazawa, T. Nagaoka, T. Takahashi, K. Yamamoto, J. Ando, A. Yoshida. Effects of shear stress on the gene expression of endothelial nitric oxide synthase, endothelin-1, and thronmomodulin in human retinal microvascular endothelial cells. Invest. Ophthalmol. Vis. Sci. 52: 8496-8504, 2011

T. Aoki, M. Nishimura, T. Matsuoka, K. Yamamoto, T. Furuyashiki, H. Kataoka, S. Kitaoka, R. Ishibashi, A. Ishibazawa, S. Moyamoto, R. Morishita, J. Ando, N. Hashimoto, K. Nozaki, S. Narumiya. PGE2 -EP2 receptor signaling in endothelium is activated by hemodynamic stress and induces cerebral aneurysm through an amplifying loop via NF-κB. Br. J. Pharmacol. 163: 1237-1249, 2011

J. Ando and　K. Yamamoto. Effects of shear stress and stretch on endothelial cells. Antioxid. Redox Signal. 15: 1389-1403, 2011

K. Yamamoto and J. Ando, “Molecular Mechanisms Underlying Mechanosensing in Vascular Biology” in Masaki Noda (ed.), Mechanosensing Biology, Springer, Tokyo, pp 21-37, 2011

[2010]

K. Yamamoto and J. Ando. Differentiation of stem/progenitor cells into vascular cells in response to fluid mechanical forces. J. Biorheol. 24: 1-10, 2010

Y-M. Chen, T. Kurokawa, T. Tominaga, K. Yasuda, Y. Osada, J-P. Gong, K. Yamamoto, J. Ando. 
Study on the sliding friction of endothelial cells cultured on hydrogel and the role of glycocalyx on friction reduction.
 Adv. Eng. Mater. 12: B628-B636, 2010

J. Ando and K. Yamamoto. “Shear-stress-sensing and response mechanisms in vascular endothelial cells” in T. Sasano and O. Suzuki (eds.), Interface Oral Health Science 2009, Springer, Tokyo, pp 3-9, 2010

【2009】

T. Masumura#,　K. Yamamoto#, N. Shimizu,　S. Obi, and J. Ando. (# These authors equally contributed to this work.) Shear Stress Increases Expression of the Arterial Endothelial Marker EphrinB2 in Murine ES Cells via the VEGF-Notch Signaling Pathways. Arteioscler. Throm. Vasc. Biol. 29: 2125-2131, 2009

J. Ando and K. Yamamoto. Vascular Mechanobiology: Endothelial Cell Responses to Fluid Shear Stress. Circ. J. 73: 1983-1992, 2009

M. Koga, R. Sudo, Y. Abe, K. Yamamoto, J. Ando, M. Ikeda, and K. Tanishita. Contribution of rat endothelial progenitor cells on three-dimensional network formation in vitro. Tissue Eng. 15: 2727-2739, 2009

S. Obi, K. Yamamoto, N. Shimizu, S. Kumagaya, T. Masumura, T. Sokabe, T. Asahara, and J. Ando. Fluid shear stress induces arterial differentiation of endothelial progenitor cells. J. Appl. Physiol. 106: 203-211, 2009

H. Huang, Y-M. Zhou, K. Takamizawa, H. Ishibashi-Ueda, J. Ando, K. Kanda, H. Yaku, and Y. Nakayama: In vitro maturation of “Biotube” vascular grafts induced by a 2-day pulsatile flow loading. J. Biomed. Mat. Res. 91: 320-328, 2009

【2008】

N. Shimizu#, K. Yamamoto#, S. Obi, S. Kumagaya, T. Masumura, Y. Shimano, K. Naruse, J. K. Yamashita, T. Igarashi, and J. Ando. (# These authors equally contributed to this work.) Cyclic strain induces mouse embryonic stem cell differentiation into vascular smooth muscle cells by activating PDGF receptor b, J. Appl. Physiol., 104: 766-772, 2008

M. Toda, K. Yamamoto, N. Shimizu, S. Obi, S. Kumagaya, T. Igarashi, A. Kamiya, and J. Ando, Differential gene responses in endothelial cells exposed to a combination of shear stress and cyclic stretch, J. Biotechnol., 133: 239-244, 2008

M. Tsuda, E. Toyomitsu, T. Komatsu, T. Masuda, E. Kunifusa, K. Nasu-Tada, S. Koizumi, K. Yamamoto, J. Ando and K. Inoue, Fibronectin/integrin system is involved in P2X4 receptor upregulation in the spinal cord and neuropathic pain after nerve injury, Glia, 56: 579-585, 2008

【2007】

K. Yamamoto, N. Shimizu, S. Obi, S. Kumagaya, Y. Taketani, A. Kamiya, and J. Ando: Involvement of cell-surface ATP synthase in flow-induced ATP release by vascular endothelial cells. Am. J. Physiol. Heart Circ. Physiol. 293: H1646-H1653, 2007

S. Sugiyama, K. Yamamoto, N. Nishimura, M. Nakagawa, Y. Maruta, and J. Ando: Adequate design of customized cDNA microarray for convention multiple gene expression analysis. J. Biosci. Bioeng. 103:74-81, 2007

K. Hayashida, K. Kanda, H. Yaku, J. Ando, and Y, Nakayama: Development of an in vivo tissue-engineered autologoue heart valve (the Biovalve): Preparation of prototype model. J. Thorac. Cardiovasc. Surg. 134:152-159, 2007

N. Koshiba, J. Ando, X. Chen, and Hisada, T: Multiphysics simulation of blood flow and LDL transport in a porohyperelastic arterial wall model. J. Biomech. Eng. 129:374-85, 2007

【2006】

K. Yamamoto, T. Sokabe, T. Matsumoto, K. Yoshimura, M. Shibata, N. Ohura, T. Fukuda, T. Sato, K. Sekine, S. Kato, M. Isshiki, T. Fujita, H. Masuda, M. Kobayashi, K. Kawamura, A. Kamiya, and J. Ando. Impaired flow-dependent control of vascular tone and remodeling in P2X4-deficient mice. Nat. Med.,　12: 133-137, 2006. PDF See also, NEWS AND VIEWS

H. Nakatsuka, T. Sokabe, K. Yamamoto, Y. Sato, K. Hatakeyama, A. Kamiya, and J. Ando. Shear stress induces hepatocyte PAI-1 gene expression through cooperative Sp1/Ets-1 activation of transcription. Am. J. Phsyiol. Gastrointest. Liver Physiol. 291:G26-G34, 2006

J.R. Mackley, J. Ando, P. Herzyk, and S.J. Winder: Phenotypic responses to mechanical stress in fibroblasts from tendon, cornea and skin. Biochem. J. 396:307-316, 2006

M. Nakamura, M. Mie, H. Funabashi, K. Yamamoto, J. Ando, and E. Kobatake. Cell-surface-localized ATP detection with immobilized firefly luciferase. Analytical Biochemistry. 352:61-67, 2006 PDF

S. Ueno, J. Ando, H. Fujita, T. Sugawara, Y. Jimbo, K. Itaka, K. Kataoka, T. Ushida: The state of the art of nanobioscience in Japan. IEEE Trans. NanoBiosci. 5:54-65, 2006

【2005】

K. Yamamoto, T. Sokabe, T. Watabe, K. Miyzono, J. K. Yamashita, S. Obi, N. Ohura, A. Matsushita, A. Kamiya, and J. Ando. Fluid shear stress induces differentiation of Flk-1-positive embryonic stem cells into vascular endothelial cells in vitro. Am. J. Physiol Heart Circ. Physiol, 288: H1915-1924, 2005. PDF

H. Huang, Y. Nakayama, K. Qin, K. Yamamoto, J. Ando, J. Yamashita, H. Itoh, K. Kanda, H. Yaku, Y. Okamoto, Y. Nemoto. Differentiation from embryonic stem cells to vascular wall cells under in vitro pulsatile flow loading. J. Artif. Organs 8:110-118. 2005

Y.M. Chen, N. Shiraishi, H. Satokawa, A. Kakugo, T. Narita, J.P. Gong, Y. Osada, K. Yamamoto, and J. Ando. Cultivation of endothelial cells on adhesive protein-free synthetic polymer gels. Biomaterials 26:4588-4596, 2005

M. Shibata, S. Ichioka, J. Ando, T. Togawa, and A. Kamiya. Non-linear regulation of capillary perfusion in relation to ambient pO2 changes in skeletal muscle. Eur. J. Appl. Physiol 94: 352-355, 2005 PDF

M. Shibata, S. Ichioka, and A. Kamiya. Estimating oxygen consumption rates of arteriolar walls under physiological condition in rat skeletal muscle, Am. J. Physiol. Heart Circ, Physiol 289: H295-H300, 2005 PDF

Y. Asano, S. Ichioka, M. Shibata, J. Ando, and T. Nakatsuk. Sprouting from arterovenous shunt vessels with increased blood flow, Med. & Biol. Eng. & Comput., 43: 126-130, 2005

【2004】

T. Sokabe, K. Yamamoto, N. Ohura, H. Nakatsuka, K. Qin, S. Obi, A. Kamiya, and J. Ando. Differential regulation of urokinase-type plasminogen activator expression by fluid shear stress in human coronary artery endothelial cells. Am. J. Physiol. Heart Circ, Physiol 287: H2027-H2034, 2004.

E. Warabi, Y. Wada, H. Kajiwara, M. Kobayashi, N. Koshiba, T. Hisada, M. Shibata, J. Ando , M. Tsuchiya, T. Kodama, amd N. Noguch. Effect on endothelial cell gene expression of shear stress, oxygen concentration, and low-density lipoprotein as studied by a novel flow cell culture system, Free Radical Biology & Medicine, 37: 682-694, 2004

S. Ichioka, S. Kudo, K. Tokioka, M. Shibata, J. Ando, N. Sekiya, T. Nakatsuka. A symmetrical dorsal island double flap in the mouse, Eur J Plast Surg, 27: 29-32, 2004

S. Ichioka, S. Kudo, M. Shibata, J. Ando, N. Sekiya, T. Nakatsuka. Bone marrow cell implantation improves flap viability after ischemia-reperfusion injury, Ann Plast Surg, 52: 414-418, 2004

【2003】

K. Yamamoto, T. Takahashi, T. Asahara, N. Ohura, T. Sokabe, A. Kamiya, and J. Ando. Proliferation, Differentiation, and Tube Formation by Endothelial Progenitor Cells in Response to Fluid Shear Stress. J. Appl. Physiol. 95: 2081-2088, 2003. PDF

N. Ohura, K. Yamamoto, S. Ichioka, T. Sokabe, H. Nakatsuka, A. Baba, M. Shibata, T. Nakatuska, K. Harii, Y. Wada, T. Kohro, T. Kodama, and J. Ando. Global Analysis of Shear Stress-Responsive Genes in Vascular Endothelial Cells. Journal of Atherosclerosis and Thrombosis. 10: 304-313, 2003.

K. Yamamoto, T. Sokabe, N. Ohura, H. Nakatsuka, A. Kamiya, and J. Ando. Endogenously released ATP mediates shear-stress-induced Ca2+ influx into pulmonary artery endothelial cells. Am. J. Physiol. 285: H793-H803, 2003. PDF

M. Iwasaka, K. Yamamoto, J. Ando, and S. Ueno. Verification of magnetic field gradient effects on medium convection and cell adhesion. J. Appl. Phys, 93: 6715-6717, 2003. PDF

D. Kaneko, T. Narita, J.P. Gong, Y. Osada, J. Ando, K. Yamamoto, S. Ohnishi, V.V. Yaminsky: Thickness decrease of a grafted polyelectrolyte membrane exposed to shear flow. J. Polym. Sci. Part B:Polym. Phys. 41:2808-2815, 2003

S. Ichioka, M. Minegishi, M. Iwasaka, M. Shibata, T. Nakatsuka, J. Ando, and S. Ueno: Skin temperature changes induced by strong static magnetic field exposure. Bioelectromagnetics 24:380-386, 2003

【2002】

M. Isshiki, J. Ando, K. Yamamoto, T. Fujita, Y. Ying and R. G. W. Anderson. Site of Ca2+ wave initiation move with caveolae to the trailing edge of migrating cells. J. Cell Sci. 115: 475-484, 2002

T.C. Minh. S. Ichioka, T. Nakatsuka, J. Kawai, M. Shibata, J. Ando, and K. Harii,: Effect of hyperthermic preconditioning on the survival of ischemia-reperfused skin flaps: A new skin-flap model in the mouse. J. Reconstructive Microsurgery 18:115-120, 2002

T.C. Minh, S. Ichioka, K. Harii, M. Shibata, J. Ando, and T. Nakatsuka:Dorsal bipedicled island skin flap: a new flap model in mice. Scand J Plast Reconstr Surg Hand Surg 36: 262-267, 2002

H. Matsuoka , K. Hashimoto, S. Horikiri, M. Saito, K. Yamamoto, J. Ando. Single-cell imaging of the Ca2+ influx into bovine endothelial cells occurring in response to an alternating electric stimulus. Analytical Sciences. 18: 1205-1208, 2002

S. Ichioka, T.C. Minh, M. Shibata, T. Nakatsuka, N. Sekiya, J. Ando, and K. Harii: In vivo model for visualizing flap microcirculatin of ischemia-reperfusion. Micorsurgery 22:304-310, 2002

【2001】

R. Korenaga, K. Yamamoto, N. Ohura, T. Sokabe, A. Kamiya, and J. Ando: Sp1-mediated downregulation of P2X4 receptor gene transcription in endothelial cells exposed to shear stress. Am. J. Physiol Heart Circ. Physiol. 280: H2214-H2221, 2001

M. Shibata, S. Ichioka, J. Ando, and A. Kamiya: Microvascular and interstitial PO2 measurements in rat skeletal muscle by phophorescence quenching. J. Appl. Physiol. 91: 321-327, 2001

S. Kato, J. Ando, and T. Matsuda: mRNA expression on shape-engineered endothelial cells: Adhesion molecules ICAM-1 and VCAM-1. J. Biomed. Mater. Res. 54:366-372, 2001

M. Negishi, D. Lu, Y-Q Zhang, Y. Sawada, T. Sasaki, T. Kayo, J. Ando, T. Izumi, M. Kurabayashi, I. Kojima, H. Masuda, and T. Takeuchi: Upregulatory expression of furin and Transforming growth factor-b by fluid shear stress in vascular endothelial cells. Arterioscler Thromb Vasc Biol. 21:785-790, 2001

【1996-2000】

K. Yamamoto, R. Korenaga, A. Kamiya, and J. Ando: Fluid shear stress activates Ca2+ influx into human endothelial cells via P2X4 purinoceptors. Circ. Res. 87:385-391, 2000

K. Yamamoto, R. Korenaga, A. Kamiya, Z. Qi, M. Sokabe, and J. Ando: P2X4 receptors mediate ATP-induced calcium influx in human vascular endothelial cells. Am. J. Physiol Heart Circ. Physiol. 279:H285-H292, 2000

J. Ando, R. Korenaga, and A. Kamiya: Shear Stress-Dependent Regulation of Endothelial Cell Functions. In "New Frontier in Vascular Biology; Thrombosis & Hemostasis", K. Suzuki et al. eds., Eibun Press, Osaka, pp199-215, 2000

J. Ando, R. Korenaga, and A. Kamiya: Flow-induced endothelial gene regulation. In "Mechanical Forces and the Endothelium", P.I. Lelkes ed., Harwood Academic Publishers, London, pp111-126, 1999

M. Yamaguchi, H. Machida, R. Korenaga, N. Toyama-Sorimachi, J. Ando, M. Miyasaka, T. Matsumoto, H. Nakano, K. Kumada, and M. Takeda: The effect of flow on the neutrophil-mediated Ca2+ responses In human vascular endothelial cells stimulated by endotoxin. Jpn. J. Surg. 29:966-969, 1999

M. Nagase, J. Abe, K. Takahashi, J. Ando, S. Hirose, and T. Fujita: Genomic organization and regulation of expression of the lectin-like oxidized low-density lipoprotein receptor (LOX-1) gene. J. Biol. Chem. 273:33702-33707, 1998

K. Nakai, I. Sakuma, T. Ohta, J. Ando, A. Kitabatake, Y. Nakazato, and T. Takahashi: Permeability characteristics of hemoglobin derivatives across cultured endothelial cell monolayers. J. Lab. Clin. Med. 132:313-319, 1998.

T. Murase, N. Kume, R. Korenaga, J. Ando, T. Sawamura, T. Masaki, and T. Kita: Fluid shear stress transcriptionally induces lectin-like oxidized LDL receptor-1 in vascular endothelial cells. Circ. Res. 83:328-333, 1998

S. Tsuzuki, N. Toyama-Sorimachi, F. Kitamura, H. Tusboi, J. Ando, T. Sakurai, N. Morii, S. Narumiya, and M. Miyasaka: Intracellular signal-transducing elements involved in transendothelial migration of lymphoma cells. Jpn. J. Cancer Res. 89: 571-577, 1998

K. Masatugu, H. Itoh, T-H. Chun, Y. Ogawa, N. Tamura, J. Yamashita, K. Doi, M. Inoue, Y. Fukunaga, N. Sawada, T. Saito, R. Korenaga, J. Ando, and K. Nakao: Physiologic shear stress suppresses endothelin-converting enzyme-1 expression in vascular endothelial cells. J. Cardiovasc. Pharmacol. 31: S42-S45, 1998

M. Isshiki, J. Ando, R. Korenaga, H. Kogo, T. Fujimoto, T. Fujita, and A. Kamiya: Endothelial Ca2+ waves preferentially originate at specific loci in caveolin-rich cell edges. Proc. Natl. Acad. Sci. U.S.A. 95: 5009-5014, 1998

H. Watanabe, R. Takahashi, X-X. Zhang, Y. Goto, H. Hayashi, J. Ando, M. Isshiki, M. Seto, H. Hidaka, I. Niki, and R. Ohno: An essential role of myosin light-chain kinase in the regulation of agonist- and fluid-flow-stimulated Ca2+ influx in endothelial cells. FASEB J 12: 341-348, 1998

K. Kosaki, J. Ando, R. Korenaga, T. Kurokawa, and A. Kamiya: Fluid shear stress increases the production of granulocyte-macrophage colony-stimulating factor by endothelial cells via mRNA stabilization. Circ. Res. 81:794-803, 1998

Y. Takada, C. Kato, S. Kondo, R. Korenaga, and J. Ando: Cloning of cDNAs encoding G protein-coupled receptor expressed in human endothelial cells exposed to fluid shear stress. Biochem. Biophys. Res. Commun. 240: 737-741, 1997

R. Korenaga, J. Ando, K. Kosaki, M. Isshiki, Y. Takada, and A. Kamiya: Negative transcriptional regulation of the VCAM-1 gene by fluid shear stress in murine endothelial cells. Am. J. Physiol. 273: C1506-C1515, 1997

T. Chun, H. Itoh, Y. Ogawa, N. Tamura, K. Takaya, T. Igaki, J. Yamashita, K. Doi, M. Inoue, K. Masatsugu, R. Korenaga, J. Ando, and K. Nakao: Shear stress augments expression of C-type natriuretic peptide and adrenomedulin. Hypertension 29:1296-1302, 1997

M. Miyasaka, H. Kawashima, R. Korenaga, and J. Ando: Involvement of selectins in atherogenesis: A primary or secondary event? Atherosclerosis IV: Recent Advances in Atherosclerosis Research, New York Academy of Sciences 811:25-35, 1997

J. Ando, H. Tsuboi, R. Korenaga, K. Takahashi, K. Kosaki, M. Isshiki, T. Tojo, Y. Takada, and A. Kamiya: Differential display and cloning of shear stress-responsive messenger RNAs in human endothelial cells. Biochem. Biophys. Res. Commun. 225: 347-351, 1996

Y. Wang, W.S. Shin, H. Kawaguchi, M. Inukai, M. Kato, A. Sakamoto, Y. Uehara, M. Miyamoto, N. Shimamoto, R. Korenaga, J. Ando, and T. Toyo-oka: Contribution of sustained Ca2+ elevation for nitric oxide production in endothelial cells and subsequent modulation of Ca2+ transient in vascular smooth muscle cells in coculture. J. Biol. Chem. 271:5647-5655, 1996

J. Ando, H. Tsuboi, R. Korenaga, K. Kosaki, M. Isshiki, Y. Takada, and A. Kamiya: Fluid shear stress differentialy modulates adhesion molecule expression in human vascular endothelial cells. In "Organ Microcirculation: Bridging between Basic and Clinical Sciences", M. Tshuchiya et al. eds., Excerpta Medica, Tokyo pp61-68, 1996

J. Ando and A. Kamiya: Flow-dependent regulation of gene expression in vascular endothelial cells. Jpn. Heart J. 37: 19-32, 1996

A. Kamiya and J. Ando: Responses of vascular endothelial cells to fluid shear stress: Mechanism. In "Biomechanics-Functional Adaptation and Remodeling", K. Hayashi et al. eds., Springer-Verlag, Tokyo, pp29-56, 1996

【1991-1995】

H. Tsuboi, J. Ando, R. Korenaga, Y. Takada, and A. Kamiya: Flow stimulates ICAM-1 expression time- and shear stress-dependently in human endothelial cells. Biochem. Biophys. Res. Commun. 206:988-996, 1995

R. Korenaga, J. Ando, H. Tsuboi, K. Kosaki, M. Isshiki, N. Toyama-Sorimachi, and A. Kamiya: Flow regulates the gene expression of VCAM-1 (vascular cell adhesion molecule-1) in cultured mouse endothelial cells. In "Microcirculation Annual", Tsuchiya et al. eds., Nihon-Igakukan, Tokyo, pp. 147-148, 1995

H. Tsuboi, J. Ando, R. Korenaga, Y. Takada, and A. Kamiya: Flow stimulates ICAM-1 expression in cultured human endothelial cells. In "Microcirculation Annual", Tsuchiya et al. eds., Nihon-Igakukan, Tokyo, pp. 33-34, 1995

J. Ando, H. Tsuboi, R. Korenaga, Y. Takada, N.Toyama-Sorimachi, M. Miyasaka, and A. Kamiya: Down-regulation of vascular adhesion molecule-1 by fluid shear stress in cultured mouse endothelial cells. Atherosclerosis III: Recent Advances in Atherosclerosis Research, Ann N Y Acad Scie 748:148-157, 1995

Y. Takada, F. Shinkai, S. Kondo, S. Yamamoto, H. Tsuboi, R. Korenaga, and J. Ando: Fluid shear stress increases the expression of thrombomodulin by cultured human endothelial cells. Biochem. Biophys. Res. Commun. 205:1345-1352, 1994

W. Yang, J. Ando, R. Korenaga, T. Toyo-oka, and A. Kamiya: Exogenous nitric oxide inhibits proliferation of cultured vascular endothelial cells. Biochem. Biophys. Res. Commun. 203:1160-1167, 1994

J. Ando, H. Tsuboi, R. Korenaga, Y. Takada, N.Toyama-Sorimachi, M. Miyasaka, and A. Kamiya: Shear stress inhibits the adhesion of cultured mouse endothelial cells to lymphocytes by down-regulating VCAM-1 expression. Am. J. Physiol. 267:C679-C687, 1994

J. Ando, A. Ohtsuka, Y. Katayama, R. Korenaga, C. Ishikawa, and A. kamiya: Intracellular calcium response to directly applied mechanical shearing force in cultured vascular endothelial cells. Biorheology 31:57-68, 1994

R. Korenaga, J. Ando, H. Tsuboi, W. Yang, I. Sakuma, T. Toyo-oka, and A. Kamiya: Laminar flow stimulates ATP- and shear stress-dependent nitric oxide production in cultured bovine endothelial cells. Biochem. Biophys. Res. Commun. 198:213-219, 1994

A. Kamiya and J. Ando: Fluid shear stress and vascular endothelial cell biomechanics. In "Clinical Biomechanics and Related Research", Y. Hirasawa, C.B. Sledge, S.L.-Y. Woo eds., Springer-Verlag Tokyo pp. 255-271, 1994

A. Kamiya, R. Korenaga, and J. Ando: Endothelial cell responses to fluid shear stress. In"Endothelium-Derived Factors and Vascular Functions",T. Masaki ed., Elsevier Science Amsterdam pp. 103-112, 1994

R. Korenaga, J. Ando, A. Ohtsuka, I. Sakuma, W. Yang, T. Toyo-oka, and A. Kamiya: Close correlation between cytoplasmic Ca++ levels and release of an endothelium-derived relaxing factor from cultured endothelial cells. Cell Struct. Funct. 18:95-104, 1993

A. Ohtsuka, J. Ando, R. Korenaga, A. Kamiya, N. Toyama-Sorimachi, and M. Miyasaka: The effect of flow on the expression of vascular adhesion molecule-1 by cultured mouse endothelial cells. Biochem. Biophys. Res. Commun. 193:301-310, 1993

J. Ando, A. Ohtsuka, R. Korenaga, T. Kawamura, and A. Kamiya: Wall shear stress rather than shear rate regulates cytoplasmic Ca++ responses to flow in vascular endothelial cells. Biochem. Biophys. Res. Commun. 190:716-723, 1993

J. Ando and A. Kamiya: Blood flow and vascular endothelial cell function. Frontiers Med. Biol. Engng 5:245-264, 1993

A. Kamiya and J. Ando: Vascular endothelial cell functions and biomechanics. Endothelium 1: 127-130, 1993
J. Ando, A. Ohtsuka, R. Korenaga, and A. Kamiya: Effect of extracellular ATP level on flow-induced Ca++ response in cultured vascular endothelial cells. Biochem. Biophys. Res. Commun. 179:1192-1199, 1991

O. Ono, J. Ando, A. Kamiya, Y. Kuboki, and H. Yasuda: Flow effects on cultured vascular endothelial and smooth muscle cell functions. Cell Struct. Funct. 16:365-374, 1991

J. Ando, S. M. Albelda, and E. M. Levine: Culture of human adult endothelial cells in liquid-liquid interfaces: A new approach to the study of cell matrix interactions. In Vitro Cell Dev. Biol. 27A:525-532, 1991

J. Ando, A. Kawarada, M. Shibata, K. Yamakoshi, and A. Kamiya: Pressure-volume relationships of finger arteries in healthy subjects and patients with coronary atherosclerosis measured non-invasively by photoelectric plethysmography. Jpn. Circ. J. 55:567-575, 1991

J. Ando, S. Araya, Y. Katayama, A. Ohtsuka, A. Kamiya: Flow-induced calcium response in cultured vascular endothelial cells. In "The Regulation of Coronary Blood Flow", Inoue et al. eds., Springer-Verlag Tokyo pp 230-241, 1991

【1986-1990】

A. Kamiya, J. Ando, M. Shibata, and H. Wakayama: The efficiency of the vascular -tissue system for oxygen transport in the skeletal muscle. Microvasc. Res. 39:169-185, 1990

J. Ando, T. Komatsuda, C. Ishikawa, and A. Kamiya: Fluid shear stress enhances DNA synthesis in cultured endothelial cells during repair of mechanical denudation. Biorheology 27:675-684, 1990

J. Ando, Y. Katayama, S. Araya, A. Otsuka, A. Kamiya: Shear-sensing mechanism in cultured vascular endothelial cells. In "Microcirculation Annual", Tsuchiya et al. eds., Nihon-Igakukan, Tokyo, pp. 141-142, 1990

T. Kohya, F. Tomita, K. Itoh, Y. Suzuki, N. Kawabata, J. Ando, and H. Yasuda: Silent myocardial ischemia during holter monitoring in ischemic heart disease. Jpn. Circ. J. 53:1399-1406, 1989

J. Ando, T. Komatsuta, and A. Kamiya: Cytoplasmic calcium response to fluid shear stress in cultured vascular endothelial cells. In Vitro Cell. Dev. Biol. 24:871-877, 1988

H. Nomura, C. Ishikawa, T. Komatsuda, J. Ando, and A. Kamiya: A disk type apparatus for applying fluid shear stress on cultured endothelial cell. Biorheology 25:461-471, 1988

A. Kamiya, J. Ando, M. Shibata, and H. Masuda: Roles of fluid shear stress in physiological regulation of vascular structure and function. Biorheology 25:271-278, 1988

J. Ando, C. Ishikawa, T. Komatsuda, and A. Kamiya: The effect of fluid shear stress on the growth behavior of vascular endothelial cells. In "Roles of Blood Flow in Atherogenesis", Yoshida et al. eds., Springer-Verlag, Tokyo, pp. 195-200, 1988

J. Ando, H. Nomura, and A. Kamiya: The effects of fluid shear stress on the migration and proliferation of cultured endothelial cells. Microvasc. Res. 33:62-70, 1987

J. Ando, C. Ishikawa, T. Komatsuda, and A. Kamiya: Increased DNA synthesis in cultured endothelial cells induced by fluid shear stress. Proc. IV World Congress for Microcirculation Excerpta Medica, Amsterdam, pp. 123-127, 1987

J. Ando, C. Ishikawa, T. Komatsuda, and A. Kamiya: Effects of hemodynamic forces on DNA synthesis and mitosis of cultured endothelial cells. In "Microcirculation Annual", Tsuchiya et al. eds., Nihon-Igakukan, Tokyo, pp. 121-122, 1987

A. Kamiya, M. Shibata, and J. Ando: Shear stress effects on capillary permeability. In "Microcirculation An Update", Tsuchiya et al. eds., Excerpta Medica, Amsterdam, pp. 113-116, 1987

J. Ando, C. Ishikawa, T. Komatsuda, and A. Kamiya: Increased DNA synthesis in cultured endothelial cells induced by fluid shear stress. In "Microcirculation An Update", Tsuchiya et al. eds., Excerpta Medica, Amsterdam, pp.123-124, 1987

【1978-1985】

J. Ando, H. Yasuda, T. Koya, N. Matsumura, A. Miyamoto, K. Kanamori, and T. Kobayashi: Alterations in myocardial perfusion during painless ST-segment depression in patients with angina pectoris. Jpn. Heart J. 26:179-189, 1985

J. Ando, H. Yasuda, A. Miyamoto, T. Kobayashi, H. Nishijima, K. Kanamori, N. Matsumura, M. Furudate, and M. Maezawa: Myocardial perfusion and left ventricular performance during exercise-induced ST segment depression in apparently healthy subjects. Jpn. Heart J. 25:155-166, 1984

J. Ando, H. Yasuda, T. Kobayashi, A. Miyamoto, K. Kanamori, R. Murakami, and N. Matsumura: Conditions for "coronary steal" caused by coronary vasodilator in man. Jpn. Heart J. 23:79-95, 1982

T. Kobayashi, A. Miyamoto, J. Ando, and H. Yasuda: Evaluation of the left ventricular performance in patients with ischemic heart disease using radionuclide angiocardiography. Jpn. Circ. J. 45:79-90, 1981

T. Kobayashi, A. Miyamoto, J. Ando, M. Furudate, and H. Yasuda: The non-invasive evaluation of regional myocardial ischemia studied by a "stress-injected" thallium-201 myocardial imaging and a radionuclide left ventriculography. Jpn. Circ. J. 44:209-217, 1980

J. Ando, S. Kimura, T. Kobayashi, Y. Tanabe, and H. Yasuda: A case of variant angina with normal coronary arteriogram who developed acute myocardial infarction and cerebral embolism. Jpn. Heart J. 20:907-914, 1979

J. Ando, T. Kobayashi, R. Sato, and H. Yasuda: Congenital aortic regurgitaion observed in a thalidomide-deformed child. Jpn. Heart J. 19：823-827, 1978