2024
IL-27 regulates the differentiation of follicular helper NKT cells via metabolic adaptation of mitochondria.
Kamii Y, Hayashizaki K, Kanno T, Chiba A, Ikegami T, Saito M, Akeda Y, Ohteki T, Kubo M, Yoshida K, Kawakami K, Oishi K, Araya J, Kuwano K, Kronenberg M, Endo Y, Kinjo Y.
Proc Natl Acad Sci U S A
. 2024 Feb 27;121(9):e2313964121. doi: 10.1073/pnas.2313964121.

  本学プレスリリース
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Glycolipid antigen recognition by invariant natural killer T cells and its role in homeostasis and antimicrobial responses.
Hayashizaki K, Kamii Y, Kinjo Y.
Front Immunol. 2024 May 28;15:1402412. doi: 10.3389/fimmu.2024.1402412. eCollection 2024.

Unveiling the role of preceding seasonal influenza in the development of bacteremic pneumococcal pneumonia in older adults before the COVID-19 pandemic in Japan.
Tamura K, Shimbashi R, Kasamatsu A, Chang B, Gotoh K, Tanabe Y, Kuronuma K, Oshima K, Maruyama T, Nakamatsu M, Abe S, Kasahara K, Nishi J, Arakawa Y, Kinjo Y, Suzuki M, Akeda Y, Oishi K; Adult IPD Study Group.
Int J Infect Dis. 2024 Jun;143:107024. doi: 10.1016/j.ijid.2024.107024.

Positive regulation of Hedgehog signaling via phosphorylation of GLI2/GLI3 by DYRK2 kinase.
Yoshida S, Kawamura A, Aoki K, Wiriyasermkul P, Sugimoto S, Tomiyoshi J, Tajima A, Ishida Y, Katoh Y, Tsukada T, Tsuneoka Y, Yamada K, Nagamori S, Nakayama K, Yoshida K.
Proc Natl Acad Sci U S A. 2024 Jul 9;121(28):e2320070121. doi: 10.1073/pnas.2320070121


2023
Instantaneous Clearing of Biofilm (iCBiofilm): an optical approach to revisit bacterial and fungal biofilm imaging.
Sugimoto S, Kinjo Y.
Commun Biol. 2023 Jan 23;6(1):38. doi: 10.1038/s42003-022-04396-4.

  本学プレスリリース
  JSTプレスリリース
  日経産業新聞
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Identification of lthB, a Gene Encoding a Putative Glycosyltransferase Family 8 Protein Required for Leptothrix Sheath Formation
Kunoh T, Yamamoto T, Ono E, Sugimoto S, Takabe K, Takeda M, Utada AS, Nomura N.
Appl Environ Microbiol. 2023 Mar 23:e0191922. doi: 10.1128/aem.01919-22. 

2022
Pneumococcal meningitis in adults in 2014-2018 after introduction of pediatric 13-valent pneumococcal conjugate vaccine in Japan.
Chang B, Tamura K, Fujikura H, Watanabe H, Tanabe Y, Kuronuma K, Fujita J, Oshima K, Maruyama T, Abe S, Kasahara K, Nishi J, Kubota T, Kinjo Y, Serizawa Y, Shimbashi R, Fukusumi M, Shimada T, Sunagawa T, Suzuki M, Oishi K; Adult IPD Study Group.
Sci Rep. 2022 Feb 23;12(1):3066. doi: 10.1038/s41598-022-06950-w.


Staphylococcus aureus utilizes environmental RNA as a building material in specific polysaccharide-dependent biofilms.
Chiba A, Seki M, Suzuki Y, Kinjo Y, Mizunoe Y, Sugimoto S.
npj Biofilms Microbiomes. 2022 Apr 4;8(1):17. doi: 10.1038/s41522-022-00278-z.
  本学プレスリリース
  東京大学プレスリリース
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  マイナビニュース

Dynamic changes in clinical characteristics and serotype distribution of invasive pneumococcal disease among adults in Japan after introduction of the pediatric 13-valent pneumococcal conjugate vaccine in 2013-2019.
Tamura K, Chang B, Shimbashi R, Watanabe H, Tanabe Y, Kuronuma K, Oshima K, Maruyama T, Fujita J, Abe S, Kasahara K, Nishi J, Kubota T, Kinjo Y, Fujikura H, Fukusumi M, Shimada T, Sunagawa T, Suzuki M, Yamamoto Y, Oishi K; Adult IPD Study Group.
Vaccine. 2022 May 26;40(24):3338-3344. doi: 10.1016/j.vaccine.2022.04.062.

Small-Molecule-Induced Activation of Cellular Respiration Inhibits Biofilm Formation and Triggers Metabolic Remodeling in Staphylococcus aureus.
Okuda KI, Yamada-Ueno S, Yoshii Y, Nagano T, Okabe T, Kojima H, Mizunoe Y, Kinjo Y.
mBio
. 2022 Aug 30;13(4):e0084522. doi: 10.1128/mbio.00845-22. Epub 2022 Jul 19.
  本学プレスリリース
  東京大学プレスリリース
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Porous Pellicle Formation of a Filamentous Bacterium, Leptothrix.
Kunoh T, Yamamoto T, Prasad M, Ono E, Li X, Sugimoto S, Iida E, Obana N, Takeda M, Nomura N, Utada AS.
Appl Environ Microbiol.
2022 Dec 13;88(23):e0134122. doi: 10.1128/aem.01341-22

2021
Hierarchical Model for the Role of J-Domain Proteins in Distinct Cellular Functions.
Sugimoto S, Yamanaka K, Niwa T, Terasawa Y, Kinjo Y, Mizunoe Y, Ogura T.
J Mol Biol. 2021 Feb 5;433(3):166750. doi: 10.1016/j.jmb.2020.166750. Epub 2020 Dec 11

Distribution and Variation of Serotypes and Pneumococcal Surface Protein A Clades of Streptococcus pneumoniae Strains Isolated From Adult Patients With Invasive Pneumococcal Disease in Japan.

Chang B, Kinjo Y, Morita M, Tamura K, Watanabe H, Tanabe Y, Kuronuma K, Fujita J, Oshima K, Maruyama T, Abe S, Kasahara K, Nishi J, Kubota T, Ohnishi M, Suga S, Oishi K.
Front Cell Infect Microbiol. 2021 Mar 19;11:617573. doi: 10.3389/fcimb.2021.617573. eCollection 2021.

SCD2-mediated monounsaturated fatty acid metabolism regulates cGAS-STING-dependent type I IFN responses in CD4+ T cells.
Kanno T, Nakajima T, Yokoyama S, Asou HK, Sasamoto S, Kamii Y, Hayashizaki K, Ouchi Y, Onodera T, Takahashi Y, Ikeda K, Hasegawa Y, Kinjo Y, Ohara O, Nakayama T, Endo Y.
Commun Biol. 2021 Jun 29;4(1):820. doi: 10.1038/s42003-021-02310-y.PMID: 34188173

Leptothrix cholodnii Response to Nutrient Limitation.
Kunoh T, Yamamoto T, Sugimoto S, Ono E, Nomura N, Utada AS.
Front Microbiol. 2021 Jun 24;12:691563. doi: 10.3389/fmicb.2021.691563.

Common Features and Intra-Species Variation of Cutibacterium modestum Strains, and Emended Description of the Species.
Dekio I, Okuda KI, Nishida M, Hamada-Tsutsumi S, Suzuki T, Kinoshita S, Tamura H, Ohnuma K, Murakami Y, Kinjo Y, Asahina A.
Microorganisms. 2021 Nov 12;9(11):2343. doi: 10.3390/microorganisms9112343.


2020
Intensive diagnostic management of coronavirus disease 2019 (COVID-19) in academic settings in Japan: challenge and future.
Hoshina T, Aonuma H, Ote M, Sakurai T, Saiki E, Kinjo Y, Kondo K, Okabe M, Kanuka H.
Inflamm Regen. 2020 Oct 12;40:38. doi: 10.1186/s41232-020-00147-2. eCollection 2020.

Seroepidemiological analysis of anti-pneumococcal surface protein A (PspA) immunoglobulin G by clades in Japanese population.
Morino S, Kitagami E, Nakayama H, Koizumi Y, Tanaka-Taya K, Kinjo Y, Oishi K.
Vaccine. 2020 Nov 3;38(47):7479-7484. doi: 10.1016/j.vaccine.2020.09.068. 


2019
Polyfunctional Nanofibril Appendages Mediate Attachment, Filamentation, and Filament Adaptability in Leptothrix cholodnii.
Kunoh T, Morinaga K, Sugimoto S, Miyazaki S, Toyofuku M, Iwasaki K, Nomura N, Utada AS.
ACS Nano
.
 2019 Dec 5. doi: 10.1021/acsnano.9b04663
      日経新聞デジタル版>

Roles of lytic transglycosylases in biofilm formation and β-lactam resistance in methicillin-resistant Staphylococcus aureus.

Lopes AA, Yoshii Y, Yamada S, Nagakura M, Kinjo Y, Mizunoe Y, Okuda KI.

Antimicrob Agents Chemother. 2019 Sep 30. pii: AAC.01277-19. doi: 10.1128/AAC.01277-19. 

Identification of a Novel Variant Form of Aspergillus fumigatus CalC and Generation of Anti-CalC Monoclonal Antibodies.
Takatsuka S, Inukai T, Kawakubo S, Umeyama T, Abe M, Ueno K, Hoshino Y, Kinjo Y, Miyazaki Y, Yamagoe S.
Med Mycol J. 2019;60(1):11-16. doi: 10.3314/mmj.18-00013.

Epidemiological and clinical features of invasive pneumococcal disease caused by serotype 12F in adults, Japan.
Shimbashi R, Chang B, Tanabe Y, Takeda H, Watanabe H, Kubota T, Kasahara K, Oshima K, Nishi J, Maruyama T, Kuronuma K, Fujita J, Ikuse T, Kinjo Y, Suzuki M, Kerdsin A, Shimada T, Fukusumi M, Tanaka-Taya K, Matsui T, Sunagawa T, Ohnishi M, Oishi K; and the Adult IPD Study Group.
PLoS One. 2019 Feb 21;14(2):e0212418. doi: 10.1371/journal.pone.0212418. eCollection 2019.

Efficacy of T-2307, a novel arylamidine, against ocular complications of disseminated candidiasis in mice.
Abe M, Nakamura S, Kinjo Y, Masuyama Y, Mitsuyama J, Kaku M, Miyazaki Y.
J Antimicrob Chemother. 2019 Feb 7. doi: 10.1093/jac/dkz020. [Epub ahead of print]

Redundant and Distinct Roles of Secreted Protein Eap and Cell Wall-Anchored Protein SasG in Biofilm Formation and Pathogenicity of Staphylococcus aureus.
Yonemoto K, Chiba A, Sugimoto S, Sato C, Saito M, Kinjo Y, Marumo K, Mizunoe Y.
Infect Immun. 2019 Jan 22. pii: IAI.00894-18. doi: 10.1128/IAI.00894-18. [Epub ahead of print]

Neutrophil-mediated antifungal activity against highly virulent Cryptococcus gattii strain R265.
Ueno K, Yanagihara N, Otani Y, Shimizu K, Kinjo Y, Miyazaki Y.
Med Mycol. 2019 Jan 18. doi: 10.1093/mmy/myy153. [Epub ahead of print]

The phytosphingosine-CD300b interaction promotes zymosan-induced, nitric oxide-dependent neutrophil recruitment.
Takahashi M, Izawa K, Urai M, Yamanishi Y, Maehara A, Isobe M, Matsukawa T, Kaitani A, Takamori A, Uchida S, Yamada H, Nagamine M, Ando T, Shimizu T, Ogawa H, Okumura K, Kinjo Y, Kitamura T, Kitaura J.
Sci Signal. 2019 Jan 15;12(564). pii: eaar5514. doi: 10.1126/scisignal.aar5514.

A dendritic cell-based systemic vaccine induces long-lived lung-resident memory Th17 cells and ameliorates pulmonary mycosis.
Ueno K, Urai M, Sadamoto S, Shinozaki M, Takatsuka S, Abe M, Otani Y, Yanagihara N, Shimizu K, Iwakura Y, Shibuya K, Miyazaki Y, Kinjo Y.
Mucosal Immunol. 2019 Jan;12(1):265-276. doi: 10.1038/s41385-018-0094-4. Epub 2018 Oct 2.


2018
Mouse LIMR3/CD300f is a negative regulator of the antimicrobial activity of neutrophils.
Ueno K, Urai M, Izawa K, Otani Y, Yanagihara N, Kataoka M, Takatsuka S, Abe M, Hasegawa H, Shimizu K, Kitamura T, Kitaura J, Miyazaki Y, Kinjo Y.
Sci Rep. 2018 Nov 27;8(1):17406. doi: 10.1038/s41598-018-35699-4.

Differences in Ocular Complications Between Candida albicans and Non-albicans Candida Infection Analyzed by Epidemiology and a Mouse Ocular Candidiasis Model.
Abe M, Kinjo Y, Ueno K, Takatsuka S, Nakamura S, Ogura S, Kimura M, Araoka H, Sadamoto S, Shinozaki M, Shibuya K, Yoneyama A, Kaku M, Miyazaki Y.
Front Microbiol. 2018 Oct 17;9:2477. doi: 10.3389/fmicb.2018.02477. eCollection 2018.

Functions of CD1d-Restricted Invariant Natural Killer T Cells in Antimicrobial Immunity and Potential Applications for Infection Control.
Kinjo Y, Takatsuka S, Kitano N, Kawakubo S, Abe M, Ueno K, Miyazaki Y.
Front Immunol. 2018 Jun 6;9:1266. doi: 10.3389/fimmu.2018.01266. eCollection 2018. Review.

Intraspecies variation in the efficacy of adjunctive recombinant interferon-γ therapy against cryptococcal meningoencephalitis in mice.
Ikeda-Dantsuji Y, Nakamura S, Ohno H, Inukai T, Nagi M, Ueno K, Umeyama T, Kinjo Y, Yamagoe S, Shibuya K, Miyazaki Y.
Med Mycol. 2018 Apr 1;56(3):382-386. doi: 10.1093/mmy/myx063.

Detection of bacterial DNA from central venous catheter removed from patients by next generation sequencing: a preliminary clinical study.
Okuda KI, Yoshii Y, Yamada S, Chiba A, Hironaka I, Hori S, Yanaga K, Mizunoe Y.
Ann Clin Microbiol Antimicrob. 2018 Dec 22;17(1):44. doi: 10.1186/s12941-018-0297-2.


Multitasking of Hsp70 chaperone in the biogenesis of bacterial functional amyloids.
Sugimoto S, Arita-Morioka KI, Terao A, Yamanaka K, Ogura T, Mizunoe Y.
Commun Biol. 2018 May 31;1:52. doi: 10.1038/s42003-018-0056-0. eCollection 2018.
(Selected as Editor's picks. Communications Biology first year anniversary collection)

Inhibitory effects of Myricetin derivatives on curli-dependent biofilm formation in Escherichia coli.
Arita-Morioka KI, Yamanaka K, Mizunoe Y, Tanaka Y, Ogura T, Sugimoto S.
Sci Rep. 2018 May 31;8(1):8452. doi: 10.1038/s41598-018-26748-z.


The Composition and Structure of Biofilms Developed by Propionibacterium acnes Isolated from Cardiac Pacemaker Devices.
Okuda KI, Nagahori R, Yamada S, Sugimoto S, Sato C, Sato M, Iwase T, Hashimoto K, Mizunoe Y.
Front Microbiol. 2018 Feb 14;9:182. doi: 10.3389/fmicb.2018.00182. eCollection 2018.

Broad impact of extracellular DNA on biofilm formation by clinically isolated Methicillin-resistant and -sensitive strains of Staphylococcus aureus.
Sugimoto S, Sato F, Miyakawa R, Chiba A, Onodera S, Hori S, Mizunoe Y.
Sci Rep. 2018 Feb 2;8(1):2254. doi: 10.1038/s41598-018-20485-z.

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