グリアアセンブリによる脳機能発現の制御と病態

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2. *Marui T, Torii Y, Iritani S, Habuchi C, Fujishiro H, Ohshima K, Niizato K, Hayashida S, Masaki K, Kira J, Ozaki N. (2018) The neuropathological study of myelin oligodendrocyte glycoprotein in the superior temporal gyrus and the hippocampus of schizophrenia. Acta Neuropsychiatr 22: 1-9. doi: 10.1017/neu.2018.6. (査読有)

3. Ishizuka K, Tabata H, Ito H, *Kushima I, Noda M, Yoshimi A, Usami M, Watanabe K, Morikawa M, Uno Y, Okada T, Mori D, Aleksic B, Ozaki N, Nagata KI. (2018) Possible involvement of a cell adhesion molecule, Migfilin, in brain development and pathogenesis of autism spectrum disorders. J Neurosci Res 96: 789-802. doi: 10.1002/jnr.24194. (査読有)

4. Yu Y, Lin Y, Takasaki Y, Wang C, Kimura H, Xing J, Ishizuka K, Toyama M, Kushima I, Mori D, Arioka Y, Uno Y, Shiino T, Nakamura Y, Okada T, Morikawa M, Ikeda M, Iwata N, Okahisa Y, Takaki M, Sakamoto S, Someya T, Egawa J, Usami M, Kodaira M, Yoshimi A, Oya-Ito T, *Aleksic B, Ohno K, Ozaki N. (2018) Rare loss of function mutations in N-methyl-D-aspartate glutamate receptors and their contributions to schizophrenia susceptibility. Transl Psychiatry 8: 12. doi: 10.1038/s41398-017-0061-y. (査読有)

5. Kimura H, Fujita Y, Kawabata T, Ishizuka K, Wang C, Iwayama Y, Okahisa Y, Kushima I, Morikawa M, Uno Y, Okada T, Ikeda M, Inada T, *Aleksic B, Mori D, Yoshikawa T, Iwata N, Nakamura H, Yamashita T, Ozaki N. (2017) A novel rare variant R292H in RTN4R affects growth cone formation and possibly contributes to schizophrenia susceptibility. Transl Psychiatry 7: e1214. doi: 10.1038/tp.2017.170. (査読有)

6. Ishizuka K, Fujita Y, Kawabata T, Kimura H, Iwayama Y, Inada T, Okahisa Y, Egawa J, Usami M, Kushima I, Uno Y, Okada T, Ikeda M, *Aleksic B, Mori D, Someya T, Yoshikawa T, Iwata N, Nakamura H, Yamashita T, Ozaki N. (2017) Rare genetic variants in CX3CR1 and their contribution to the increased risk of schizophrenia and autism spectrum disorders. Transl Psychiatry 7: e1184. doi: 10.1038/tp.2017.173. (査読有)

7. Kushima I, Aleksic B, Nakatochi M, Shimamura T, Shiino T, Yoshimi A, Kimura H, Takasaki Y, Wang C, Xing J, Ishizuka K, Oya-Ito T, Nakamura Y, Arioka Y, Maeda T, Yamamoto M, Yoshida M, Noma H, Hamada S, Morikawa M, Uno Y, Okada T, Iidaka T, Iritani S, Yamamoto T, Miyashita M, Kobori A, Arai M, Itokawa M, Cheng MC, Chuang YA, Chen CH, Suzuki M, Takahashi T, Hashimoto R, Yamamori H, Yasuda Y, Watanabe Y, Nunokawa A, Someya T, Ikeda M, Toyota T, Yoshikawa T, Numata S, Ohmori T, Kunimoto S, Mori D, Iwata N, *Ozaki N. (2017) High-resolution copy number variation analysis of schizophrenia in Japan. Mol Psychiatry 22: 430-440. doi: 10.1038/mp.2016.88. (査読有)

8. Takasaki Y, Koide T, Wang C, Kimura H, Xing J, Kushima I, Ishizuka K, Mori D, Sekiguchi M, Ikeda M, Aizawa M, Tsurumaru N, Iwayama Y, Yoshimi A, Arioka Y, Yoshida M, Noma H, Oya-Ito T, Nakamura Y, Kunimoto S, *Aleksic B, Uno Y, Okada T, Ujike H, Egawa J, Kuwabara H, Someya T, Yoshikawa T, Iwata N, Ozaki N. (2016) Mutation screening of GRIN2B in schizophrenia and autism spectrum disorder in a Japanese population. Sci Rep 6: 33311. doi: 10.1038/srep33311. (査読有)

9. Kimura H, Wang C, Ishizuka K, Xing J, Takasaki Y, Kushima I, *Aleksic B, Uno Y, Okada T, Ikeda M, Mori D, Inada T, Iwata N, Ozaki N. (2016) Identification of a rare variant in CHD8 that contributes to schizophrenia and autism spectrum disorder susceptibility. Schizophr Res 178: 104-106. doi: 10.1016/j.schres.2016.08.023. (査読有)

10. Ishizuka K, Kimura H, Wang C, Xing J, Kushima I, Arioka Y, Oya-Ito T, Uno Y, Okada T, Mori D, *Aleksic B, Ozaki N. (2016) Investigation of Rare Single-Nucleotide PCDH15 Variants in Schizophrenia and Autism Spectrum Disorders. PLoS One 11: e0153224. doi: 10.1371/journal.pone.0153224. (査読有)

11. Xing J, Kimura H, Wang C, Ishizuka K, Kushima I, Arioka Y, Yoshimi A, Nakamura Y, Shiino T, Oya-Ito T, Takasaki Y, Uno Y, Okada T, Iidaka T, *Aleksic B, Mori D, Ozaki N. (2016) Resequencing and Association Analysis of Six PSD-95-Related Genes as Possible Susceptibility Genes for Schizophrenia and Autism Spectrum Disorders. Sci Rep 6: 27491. doi: 10.1038/srep27491. (査読有)

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13. Takahashi T, Nakamura M, Nakamura Y, Aleksic B, Kido M, Sasabayashi D,　Takayanagi Y, Furuichi A, Nishikawa Y, Noguchi K, Ozaki N, Suzuki M. (2015) The Disrupted-in-Schizophrenia-1 Ser704Cys polymorphism and brain neurodevelopmental markers in schizophrenia and healthy subjects. Prog Neuropsychopharmacol Biol Psychiatry 56: 11-17. doi: 10.1016/j.pnpbp.2014.07.005. (査読有)

14. Yamamoto M, Kushima I, Kimura H, Hayashi A, Kawano N, Aleksic B, *Iidaka T, Ozaki N. (2015) White matter microstructure between the pre-SMA and the cingulum bundle is related to response conflict in healthy subjects. Brain Behav 5: e00375. doi: 10.1002/brb3.375. (査読有)

15. Kimura H, Tanaka S, Kushima I, Koide T, Banno M, Kikuchi T, Nakamura Y, Shiino T, Yoshimi A, Oya-Ito T, Xing J, Wang C, Takasaki Y, *Aleksic B, Okada T, Ikeda M, Inada T, Iidaka T, Iwata N, Ozaki N. (2015) Association study of BCL9 gene polymorphism rs583583 with schizophrenia and negative symptoms in Japanese population. Sci Rep 5: doi: 15705. 10.1038/srep15705. (査読有)

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20. Xing J, Wang C, Kimura H, Takasaki Y, Kunimoto S, Yoshimi A, Nakamura Y, Koide T, Banno M, Kushima I, Uno Y, Okada T, *Aleksic B, Ikeda M, Iwata N, Ozaki N. (2014) Resequencing and association analysis of PTPRA, a possible susceptibility gene for schizophrenia and autism spectrum disorders. PLoS One 9: e112531. doi: 10.1371/journal.pone.0112531. (査読有)

21. *Kido M, Nakamura Y, Nemoto K, Takahashi T, Aleksic B, Furuichi A, Nakamura Y, Ikeda M, Noguchi K, Kaibuchi K, Iwata N, Ozaki N, Suzuki M. (2014) The polymorphism of YWHAE, a gene encoding 14-3-3epsilon, and brain morphology in schizophrenia: a voxel-based morphometric study. PLoS One 9: e103571. doi: 10.1371/journal.pone.0103571. (査読有)

22. Wang C, Koide T, Kimura H, Kunimoto S, Yoshimi A, Nakamura Y, Kushima I, Banno M, Kawano N, Takasaki Y, Xing J, Noda Y, Mouri A, *Aleksic B, Ikeda M, Okada T, Iidaka T, Inada T, Iwata N, Ozaki N. (2014) Novel rare variants in F-box protein 45 (FBXO45) in schizophrenia. Schizophr Res 157: 149-156. doi: 10.1016/j.schres.2014.04.032. (査読有)

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1. *Inoue K, *Tsuda M. (2018) Microglia in neuropathic pain: cellular and molecular mechanisms and therapeutic potential. Nat Rev Neurosci 19: 138-152. doi: 10.1038/nrn.2018.2. (査読有)

2. Tashima R, Koga K, Sekine M, Kanehisa K, Kohro Y, Tominaga K, Matsushita K, Tozaki-Saitoh H, Fukazawa Y, Inoue K, Yawo H, Furue H, *Tsuda M. (2018) Optogenetic activation of non-nociceptive Aβ fibers induces neuropathic pain-like sensory and emotional behaviors after nerve injury in rats. eNeuro 5: e0450-17. doi: 10.1523/ENEURO.0450-17.2018. (査読有)

3. Ohgidani M, *Kato TA, Hosoi M, Tsuda M, Hayakawa K, Hayaki C, Iwaki R, Sagata N, Hashimoto R, Inoue K, Sudo N, Kanba S. (2017) Fibromyalgia and microglial TNF-α: Translational research using human blood induced microglia-like cells. Sci Rep 7: 11882. doi: 10.1038/s41598-017-11506-4. (査読有)

4. Kanehisa K, Shiratori-Hayashi M, Koga K, Tozaki-Saitoh H, Kohro Y, Takamori K, *Tsuda M. (2017) Specific activation of inhibitory interneurons in the spinal dorsal horn suppresses repetitive scratching in mouse models of chronic itch. J Dermatol Sci 38: 251-254. doi: 10.1016/j.jdermsci.2017.05.017. (査読有)

5. Koga K, Kanehisa K, Kohro Y, Shiratori-Hayashi M, Tozaki-Saitoh H, Inoue K, Furue H, *Tsuda M. (2017) Chemogenetic silencing of GABAergic dorsal horn interneurons induces morphine-resistant spontaneous nocifensive behaviours. Sci Rep 7: 4739. doi: 10.1038/s41598-017-04972-3. (査読有)

6. Tozaki-Saitoh H, Miyata H, Yamashita T, Matsushita K, *Tsuda M, *Inoue K. (2017) P2Y12 receptors in primary microglia activate nuclear factor of activated T-cell signaling to induce C-C chemokine 3 expression. J Neurochem 141: 100–110. doi: 10.1111/jnc.13968. (査読有)

7. Inoue K. (2017) Purinergic signaling in microglia in the pathogenesis of neuropathic pain. Proc Jpn Acad Ser B Phys Biol Sci 93: 174-182. doi: 10.2183/pjab.93.011. (査読有)

8. Nakaya M, Watari K, Tajima M, Nakaya T, Matsuda S, Ohara H, Nishihara H, Yamaguchi H, Hashimoto A, Nishida M, Nagasaka A, Horii Y, Ono H, Iribe G, Inoue R, Tsuda M, Inoue K, Tanaka A, Kuroda M, Nagata S, *Kurose H. (2017) Cardiac myofibroblast engulfment of dead cells facilitates recovery after myocardial infarction. J Clin Invest 127: 383-401. doi: 10.1172/JCI83822. (査読有)

9. *Tsuda M, Inoue K. (2016) Neuron-microglia interaction by purinergic signaling in neuropathic pain following neurodegeneration. Neuropharmacology 104: 76-81. doi: 10.1016/j.neuropharm.2015.08.042. (査読有)

10. Matsunaga N, Ikeda E, Kakimoto K, Watanabe M, Shindo N, Tsuruta A, Ikeyama H, Hamamura K, Higashi K, Yamashita T, Kondo H, Yoshida Y, Matsuda M, Ogino T, Tokushige K, Itcho K, Furuichi Y, Nakao T, Yasuda K, Doi A, Amamoto T, Aramaki H, Tsuda M, Inoue K, Ojida A, Koyanagi S, *Ohdo S. (2016) Inhibition of G0/G1 switch 2 ameliorates renal inflammation in chronic kidney disease. EBioMedicine 13: 262-273. doi: 10.1016/j.ebiom.2016.10.008. (査読有)

11. Koyanagi S, Kusunose N, Taniguchi M, Akamine T, Kanado Y, Ozono Y, Masuda T, Kohro Y, Matsunaga N, Tsuda M, Salter MW, Inoue K, *Ohdo S. (2016) Glucocorticoid regulation of ATP release from spinal astrocytes underlies diurnal exacerbation of neuropathic mechanical allodynia. Nat Commun 7: 13102. doi: 10.1038/ncomms13102. (査読有)

12. Masuda T, *Tsuda M, *Inoue K. (2016) Transcriptional regulation in microglia and neuropathic pain. Pain Manag 6: 91-94. doi: 10.2217/pmt.15.34. (査読有)

13. Tashima R, Mikuriya S, Tomiyama D, Shiratori-Hayashi M, Yamashita T, Kohro Y, Tozaki-Saitoh H, Inoue K, *Tsuda M. (2016) Bone marrow-derived cells in the population of spinal microglia after peripheral nerve injury. Sci Rep 6: 23701. doi: 10.1038/srep23701. (査読有)

14. Masuda T, Ozono Y, Mikuriya S, Kohro Y, Tozaki-Saitoh H, Iwatsuki K, Uneyama H, Ichikawa R, Salter MW, *Tsuda M, *Inoue K. (2016) Dorsal horn neurons release extracellular ATP in a VNUT-dependent manner that underlies neuropathic pain. Nat Commun 7: 12529. doi: 10.1038/ncomms12529. (査読有)

15. Matsumura Y, Yamashita T, Sasaki A, Nakata E, Kohno K, Masuda T, Tozaki-Saitoh H, Imai T, Kuraishi Y, *Tsuda M, Inoue K. (2016) A novel P2X4 receptor-selective antagonist produces anti-allodynic effect in a mouse model of herpetic pain. Sci Rep 6: 32461. doi: 10.1038/srep32461. (査読有)

16. Yamashita T, Yamamoto S, Zhang J, Kometani M, Tomiyama D, Kohno K, Tozaki-Saitoh H, *Inoue K, *Tsuda M. (2016) Duloxetine inhibits microglial P2X4 receptor function and alleviates neuropathic pain after peripheral nerve injury. PLoS One 11: e0165189. doi: 10.1371/journal.pone.0165189. (査読有)

17. Nishimura A, Sunggip C, Tozaki-Saitoh H, Shimauchi T, Numaga-Tomita T, Hirano K, Ide T, Boeynaems J.-M, Kurose H, Tsuda M, Robaye B, Inoue K, *Nishida M. (2016) Purinergic P2Y6 receptors heterodimerize with angiotensin AT1 receptors to promote angiotensin II–induced hypertension. Sci Signal 9: ra7. doi: 10.1126/scisignal.aac9187. (査読有)

18. 増田隆博, 津田誠, 齊藤秀俊, 山下智大, 高露雄太, *井上和秀 (2016) ミクログリアと神経障害性疼痛 細胞 48: 357-360. (査読有)

19. Igawa T, Abe Y, Tsuda M, Inoue K, *Ueda T. (2015) Solution structure of the rat P2X4 receptor head domain involved in inhibitory metal binding. FEBS Lett 589: 680-686. doi: 10.1016/j.febslet.2015.01.034. (査読有)

20. Shiratori-Hayashi M, Koga K, Tozaki-Saitoh H, Kohro Y, Toyonaga H, Yamaguchi C, Hasegawa A, Nakahara T, Hachisuka J, Akira S, Okano H, Furue M, Inoue K, *Tsuda M. (2015) STAT3-dependent reactive astrogliosis in the spinal dorsal horn underlies chronic itch. Nat Med 21: 927-931. doi: 10.1038/nm.3912. (査読有)

21. Masuda T, Iwamoto S, Mikuriya S, Tozaki-Saitoh H, Tamura T, *Tsuda M, *Inoue K. (2015) Transcription factor IRF1 is responsible for IRF8-mediated IL-1β expression in reactive microglia. J Pharmacol Sci 128: 216-220. doi: 10.1016/j.jphs.2015.08.002. (査読有)

22. Kohro Y, Sakaguchi E, Tashima R, Tozaki-Saitoh H, Okano H, *Inoue K, *Tsuda M. (2015) A new minimally-invasive method for microinjection into the mouse spinal dorsal horn. Sci Rep 5: 14306. doi: 10.1038/srep14306. (査読有)

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28. Matsushita K, Tozaki-Saitoh H, Kojima C, Masuda T, Tsuda M, *Inoue K, Hoka S. (2014) Chemokine (C-C motif) receptor 5 is an important pathological regulator in the development and maintenance of neuropathic pain. Anesthesiology 120: 1491-503. doi: 10.1097/ALN.0000000000000190. (査読有)

29. Masuda T, Nishimoto N, Tomiyama D, Matsuda T, Tozaki-Saitoh H, Tamura T, Kohsaka S, Tsuda M, *Inoue K. (2014) IRF8 is a transcriptional determinant for microglial motility. Purinergic Signal 10: 515-521. doi: 10.1007/s11302-014-9413-8. (査読有)

30. Masuda T, Iwamoto S, Yoshinaga R, Tozaki-Saitoh H, Nishiyama A, Mak TW, Tamura T, *Tsuda M, *Inoue K. (2014) Transcription factor IRF5 drives P2X4R+-reactive microglia gating neuropathic pain. Nat Commun 5: 3771. doi: 10.1038/ncomms4771. (査読有)

31. *Yasui M, Takashi M, Takeuchi S, Tokizane K, Tsuda M, Inoue K, Kiyama H. (2014) A chronic fatigue syndrome model demonstrates mechanical allodynia and muscular hyperalgesia via spinal microglial activation. GLIA 62: 1407-1417. doi: 10.1002/glia.22687. (査読有)

32. Shimoyama H, Tsuda M, Masuda T, Yoshinaga R, Tsukamoto K, Tozaki-Saitoh H, *Inoue K. (2014) Spinal Cord is the Primary Site of Action of the Cannabinoid CB2 Receptor Agonist JWH133 that Suppresses Neuropathic Pain: Possible Involvement of Microglia. The Open Pain Journal 7: 1-8. doi: 10.2174/1876386301407010001 (査読有)

33. Ochi-ishi R, Nagata K, Inoue T, Tozaki-Saitoh H, Tsuda M, *Inoue K. (2014) Involvement of the chemokine CCL3 and the purinoceptor P2X7 in the spinal cord in paclitaxel-induced mechanical allodynia. Mol Pain 10: 53. doi: 10.1186/1744-8069-10-53. (査読有)

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1. Kuwano N, *Kato TA, Setoyama D, Sato-Kasai M, Shimokawa N, Hayakawa K, Ohgidani M, Sagata N, Kubo H, Kishimoto J, Kang D, Kanba S. (2018) Tryptophan-kynurenine and lipid related metabolites as blood biomarkers for first-episode drug-naïve patients with major depressive disorder: an exploratory pilot case-control study. J Affect Disord 231: 74-82. doi: 10.1016/j.jad.2018.01.014. (査読有)

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3. Ohgidani M, *Kato TA, Hosoi M, Tsuda M, Hayakawa K, Hayaki C, Iwaki R, Sagata N, Hashimoto R, Inoue K, Sudo N, Kanba S. (2017) Fibromyalgia and microglial TNF-α: Translational research using human blood induced microglia-like cells. Sci Rep 7: 11882. doi: 10.1038/s41598-017-11506-4. (査読有)

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6. Setoyama D, *Kato TA, Hashimoto R, Kunugi H, Hattori K, Hayakawa K, Sato-Kasai M, Shimokawa N, Kaneko S, Yoshida S, Goto Y, Yasuda Y, Yamamori H, Ohgidani M, Sagata N, Miura D, Kang D, Kanba S. (2016) Human plasma metabolites predict severity of depression and suicidal ideation. PLoS One 11: e0165267. doi: 10.1371/journal.pone.0165267. (査読有)

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1. Ohgomori T, Yamasaki R, Kira JI, *Jinno S. (2018) Upregulation of Vesicular Glutamate Transporter 2 and STAT3 Activation in the Spinal Cord of Mice Receiving 3,3'-Iminodipropionitrile. Neurotox Res 33: 768-780. doi: 10.1007/s12640-017-9822-x. (査読有)

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2. Li G, Yamasaki R, Fang M, Masaki K, Ochi H, Matsushita T, *Kira JI. (2018) Novel disease-modifying anti-rheumatic drug iguratimod suppresses chronic experimental autoimmune encephalomyelitis by down-regulating activation of macrophages/microglia through an NF-κB pathway. Sci Rep 8: 1933. doi: 10.1038/s41598-018-20390-5. (査読有)

3. Fujita A, Ogata H, Yamasaki R, Matsushita T, *Kira JI. (2018) Parallel fluctuation of anti-neurofascin 155 antibody levels with clinico-electrophysiological findings in patients with chronic inflammatory demyelinating polyradiculoneuropathy. J Neurol Sci 384: 107-112. doi: 10.1016/j.jns.2017.11.035. (査読有)

4. Ohgomori T, Yamasaki R, Takeuchi H, Kadomatsu K, Kira JI, *Jinno S. (2017) Differential activation of neuronal and glial STAT3 in the spinal cord of theSOD1(G93A) mouse model of amyotrophic lateral sclerosis. Eur J Neurosci 46: 2001-2014. doi: 10.1111/ejn.13650. (査読有)

5. Nakamura N, Ohyagi Y, Imamura T, Yanagihara YT, Iinuma KM, Soejima N, Murai H, Yamasaki R, *Kira JI. (2017) Apomorphine Therapy for Neuronal Insulin Resistance in a Mouse Model of Alzheimer's Disease. J Alzheimers Dis 58: 1151-1161. doi: 10.3233/JAD-160344. (査読有)

6. Ohgomori T, Yamasaki R, Takeuchi H, Kadomatsu K, Kira JI, *Jinno S. (2017) Differential involvement of vesicular and glial glutamate transporters around spinal α-motoneurons in the pathogenesis of SOD1(G93A) mouse model of amyotrophic lateral sclerosis. Neuroscience 356: 114-124. doi: 10.1016/j.neuroscience.2017.05.014. (査読有)

7. Yamasaki R, Yamaguchi H, Matsushita T, Fujii T, Hiwatashi A, *Kira JI. (2017) Early strong intrathecal inflammation in cerebellar type multiple system atrophy by cerebrospinal fluid cytokine/chemokine profiles: a case control study. J Neuroinflammation 14: 89. doi: 10.1186/s12974-017-0863-0. (査読有)

7. Hayashida S, Masaki K, Yonekawa T, Suzuki SO, Hiwatashi A, Matsushita T, Watanabe M, Yamasaki R, Suenaga T, Iwaki T, Murai H, *Kira JI. (2017) Early extensive spinal white matter involvement in neuromyelitis optica. Brain Pathol 27: 249-265. doi: 10.1111/bpa.12386. (査読有)

8. Watanabe M, Masaki K, Yamasaki R, Kawanokuchi J, Takeuchi H, Matsushita T, Suzumura A, *Kira JI. (2016) Th1 cells downregulate connexin 43 gap junctions in astrocytes via microglial activation. Sci Rep 6: 38387. doi: 10.1038/srep38387. (査読有)

9. Yamasaki R, Fujii T, Wang B, Masaki K, Kido MA, Yoshida M, Matsushita T, *Kira J. (2016) Allergic Inflammation Leads to Neuropathic Pain via Glial Cell Activation. J Neurosci 36: 11929-11945. (査読有)

10. Yamasaki R, Matsushita T, Fukazawa T, Yokoyama K, Fujihara K, Ogino M, Yokota T, Miyamoto K, Niino M, Nomura K, Tomioka R, Tanaka M, Kawachi I, Ohashi T, Kaida K, Matsui M, Nakatsuji Y, Ochi H, Fukaura H, Kanda T, Nagaishi A, Togo K, Mizusawa H, Murai H, *Kira J. (2016) Efficacy of intravenous methylprednisolone pulse therapy in patients with multiple sclerosis and neuromyelitis optica. Mult Scler 22: 1337-1348. doi: 10.1177/1352458515617248. (査読有)

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18. Song ZY, Yamasaki R, Kawano Y, Sato S, Masaki K, Yoshimura S, Matsuse D, Murai H, Matsushita T, *Kira J. (2015) Peripheral blood T cell dynamics predict relapse in multiple sclerosis patients on fingolimod. PLoS One 10: e0124923. doi: 10.1371/journal.pone.0124923. (査読有)

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20. Cui Y, Masaki K, Yamasaki R, Imamura S, Suzuki SO, Hayashi S, Sato S, Nagara Y, Kawamura MF, *Kira J. (2014) Extensive dysregulations of oligodendrocytic and astrocytic connexins are associated with disease progression in an amyotrophic lateral sclerosis mouse model. J Neuroinflammation 11: 42. doi: 10.1186/1742-2094-11-42. (査読有)

21. Ainiding G, Kawano Y, Sato S, Isobe N, Matsushita T, Yoshimura S, Yonekawa T, Yamasaki R, Murai H, *Kira J. (2014) South Japan Multiple Sclerosis Genetics Consortium. Interleukin 2 receptor α chain gene polymorphisms and risks of multiple sclerosis and neuromyelitis optica in southern Japanese. J Neurol Sci 337: 147-150. doi: 10.1016/j.jns.2013.11.037. (査読有)

22. Masaki K, Suzuki SO, Matsushita T, Matsuoka T, Imamura S, Yamasaki R, Suzuki M, Suenaga T, Iwaki T, *Kira J. (2013) Connexin 43 astrocytopathy linked to rapidly progressive multiple sclerosis and neuromyelitis optica. PLoS One 8: e72919. doi: 10.1371/journal.pone.0072919. (査読有)

23. Kawamura N, Yamasaki R, Yonekawa T, Matsushita T, Kusunoki S, Nagayama S, Fukuda Y, Ogata H, Matsuse D, Murai H, *Kira J. (2013) Anti-neurofascin antibody in patients with combined central and peripheral demyelination. Neurology 81: 714-722. doi: 10.1212/WNL.0b013e3182a1aa9c. (査読有)

24. Saitoh BY, Yamasaki R, Hayashi S, Yoshimura S, Tateishi T, Ohyagi Y, Murai H, Iwaki T, Yoshida K, *Kira J. (2013) A case of hereditary diffuse leukoencephalopathy with axonal spheroids caused by a de novo mutation in CSF1R masquerading as primary progressive multiple sclerosis. Mult Scler 19: 1367-1370. doi: 10.1177/1352458513489854. (査読有)

25. Matsushita T, Tateishi T, Isobe N, Yonekawa T, Yamasaki R, Matsuse D, Murai H, Kira J. (2013) Characteristic cerebrospinal fluid cytokine/chemokine profiles in neuromyelitis optica, relapsing remitting or primary progressive multiple sclerosis. PLoS One 8: e61835. doi: 10.1371/journal.pone.0061835. (査読有)

26. Nagara Y, Tateishi T, Yamasaki R, Hayashi S, Kawamura M, Kikuchi H, Iinuma KM, Tanaka M, Iwaki T, Matsushita T, Ohyagi Y, *Kira J. (2013) Impaired cytoplasmic-nuclear transport of hypoxia-inducible factor-1α in amyotrophic lateral sclerosis. Brain Pathol 23: 534-546. doi: 10.1111/bpa.12040. (査読有)

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25. Kitamura K, Watanabe Y, *Nakamura K, Sanpei K, Wakasugi M, Yokoseki A, Onodera O, Ikeuchi T, Ruwano R, Momotsu T, Narita I, Endo N. (2016) Modifiable factors associated with cognitive impairment in 1143 Japanese outpatients: The Project in Sado for Total Health (PROST). Dement Geriatr Cogn Dis EXTRA 6: 341-349. doi: 10.1159/000447963. (査読有)

26. Kutoku Y, Ohsawa Y, Kuwano R, Ikeuchi T, Inoue H, Ataka S, Shimada H, Mori H, *Sunada Y. (2015) A second pedigree with amyloid-less familial Alzheimer’s disease harbors an identical mutation in the amyloid precursor protein gene (E693delta). Intern Med 54: 205-208. doi: 10.2169/internalmedicine.54.3021. (査読有)

27. Sato Y, Bernier F, Yamanaka Y, Aoshima K, Oda Y, Ingelsson M, Lannfelt L, Miyashita A, Kuwano R, *Ikeuchi T. (2015) Plasma Desmosterol is associated with longitudinal cognitive decline in Alzheimer’s disease. Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring 1: 67-74. doi: 10.1016/j.dadm.2014.11.009. (査読有)

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29. Suzuki Y, Nakamura Y, Yamada K, Igarashi H, Kasuga K, Yokoyama Y, Ikeuchi T, Nishizawa M, Kwee IL, *Nakada T. (2015) Reduced CSF water influx in Alzheimer's disease supporting the β-amyloid clearance hypothesis. PLoS One 10: e0123708. doi: 10.1371/journal.pone.0123708. (査読有)

30. Kasuga K, Kikuchi M, Tokutake T, Nakaya A, Tezuka T, Tsukie T, Hara N, Miyashita A, Kuwano R, *Ikeuchi T. (2015) Systematic review and meta-analysis of Japanese familial Alzheimer’s disease and FTDP-17. J Hum Genet 60: 281-283. doi: 10.1038/jhg.2015.15. (査読有)

31. Yajima R, Tokutake T, Koyama A, Kasuga K, Tezuka T, Nishizawa M, *Ikeuchi T. (2015) ApoE-isoform-dependent cellular uptake of amyloid-β is mediated by lipoprotein receptor LR11/SorLA. Biochem Biophys Res Commun 456: 482-488. doi: 10.1016/j.bbrc.2014.11.111. (査読有)

32. Tokutake T, Ishikawa A, Yoshimura N, Miyashita A, Kuwano R, Nishizawa M, *Ikeuchi T. (2014) Clinical and neuroimaging features of patient with early-onset Parkinson's disease with dementia carrying SNCA p.G51D mutation. Parkinsonism Relat Disord 20: 262-264. doi: 10.1016/j.parkreldis.2013.11.008. (査読有)

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35. Tagami S, Okochi M, Yanagida K, Kodama T, Arai T, Kuwano R, Ikeuchi T, Takeda M. (2014) Relative Ratio and Level of Amyloid-β 42 Surrogate in Cerebrospinal Fluid of Familial Alzheimer Disease Patients with Presenilin 1 Mutations. Neurodegener Dis 13: 166-170. doi: 10.1159/000355258. (査読有)

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37. *Miyashita A, Wen Y, Kitamura N, Matsubara E, Kawarabayashi T, Shoji M, Tomita N, Arai H, Asada T, Harigaya Y, Ikeda M, Amari M, Hanyu H, Higuchi S, Nishizawa M, Suga M, Kawase Y, Akatsu H, Imagawa M, Hamaguchi T, Yamada M, Morihara T, Takeda M, Takao T, Nakata K, Sasaki K, Watanabe K, Nakajima K, Urakami K, Ooya T, Takahashi M, Yuzuriha T, Serikawa K, Yoshimoto S, Nakagawa R, Saito Y, Hatsuta H, Murayama S, Kakita A, Takahashi H, Yamaguchi H, Akazawa K, Kanazawa I, Ihara Y, Ikeuchi T, *Kuwano R. (2014) Lack of genetic association between TREM2 and late-onset Alzheimer’s disease in the Japanese population. J Alzheimers Dis 41: 1031-1038. doi: 10.3233/JAD-140225. (査読有)

1. Nakazato R, Kawabe K, Yamada D, Ikeno S, Mieda M, Shimba S, Hinoi E, Yoneda Y, *Takarada T. (2017) Disruption of Bmal1 impairs blood-brain barrier integrity via pericyte dysfunction. J Neurosci 37: 10052-10062. doi: 10.1523/JNEUROSCI.3639-16.2017. (査読有)

2. Effendi N, *Ogawa K, Mishiro K, Takarada T, Yamada D, Kitamura Y, Shiba K, Maeda T, Odani A. (2017) Synthesis and evaluation of radioiodinated 1-{2-[5-(2-methoxyethoxy)-1H-benzo[d]imidazol-1-yl]quinolin-8-yl}piperidin-4-amine derivatives for platelet-derived growth factor receptor beta (PDGFRbeta) imaging. Bioorg Med Chem 25: 5576-5585. doi: 10.1016/j.bmc.2017.08.025. (査読有)

3. Nakazato R, Hotta S, Yamada D, Kou M, Nakamura S, Takahata Y, Tei H, Numano R, Hida A, Shimba S, Mieda M, Hinoi E, Yoneda Y, *Takarada T. (2017) The intrinsic microglial clock system regulates interleukin-6 expression. GLIA 65: 198-208. doi: 10.1002/glia.23087. (査読有)

4. *Takarada T, Xu C, Ochi H, Nakazato R, Yamada D, Nakamura S, Kodama A, Shimba S, Mieda M, Fukasawa K, Ozaki K, Iezaki T, Fujikawa K, Yoneda Y, Numano R, Hida A, Tei H, Takeda S, Hinoi E. (2017) Bone Resorption Is Regulated by Circadian Clock in Osteoblasts. J Bone Miner Res 32: 872-881. doi: 10.1002/jbmr.3053. (査読有)

5. Liao L, Zhang S, Gu J, Takarada T, Yoneda Y, Huang J, Zhao L, Oh CD, Li J, Wang B, Wang M, *Chen D. (2017) Deletion of Runx2 in Articular Chondrocytes Decelerates the Progression of DMM-Induced Osteoarthritis in Adult Mice. Sci Rep 7: 2371. doi: 10.1038/s41598-017-02490-w. (査読有)

6. Park G, Horie T, Kanayama T, Fukasawa K, Iezaki T, Onishi Y, Ozaki K, Nakamura Y, Yoneda Y, Takarada T, *Hinoi E. (2017) The transcriptional modulator Ifrd1 controls PGC-1α expression under short-term adrenergic stimulation in brown adipocytes. FEBS J 284: 784-795. doi: 10.1111/febs.14019. (査読有)

7. Xu C, Ochi H, Fukuda T, Sato S, Sunamura S, Takarada T, Hinoi E, Okawa A, *Takeda S. (2016) Circadian Clock Regulates Bone Resorption in Mice. J Bone Miner Res 31: 1344-1355. doi: 10.1002/jbmr.2803. (査読有)

8. Takarada T, Ogura M, Nakamichi N, Kakuda T, Nakazato R, Kokubo H, Ikeno S, Nakamura S, Kutsukake T, Hinoi E, *Yoneda Y. (2016) Upregulation of Slc38a1 Gene Along with Promotion of Neurosphere Growth and Subsequent Neuronal Specification in Undifferentiated Neural Progenitor Cells Exposed to Theanine. Neurochem Res 41: 5-15. doi: 10.1007/s11064-015-1591-4. (査読有)

9. *Takarada T, Nakazato R, Tsuchikane A, Fujikawa K, Iezaki T, Yoneda Y, Hinoi E. (2016) Genetic analysis of Runx2 function during intramembranous ossification. Development 143: 211-218. doi: 10.1242/dev.128793.（査読有）

10. *Takarada T, Kou M, Hida M, Fukumori R, Nakamura S, Kutsukake T, Kuramoto N, Hinoi E, Yoneda Y. Protective upregulation of activating transcription factor-3 against glutamate neurotoxicity in neuronal cells under ischemia. (2016) J Neurosci Res 94: 378-388. doi: 10.1002/jnr.23723. (査読有)

11. Iezaki T, Ozaki K, Fukasawa K, Inoue M, Kitajima S, Muneta T, Takeda S, Fujita H, Onishi Y, Horie T, Yoneda Y, Takarada T, *Hinoi E. (2016) ATF3 deficiency in chondrocytes alleviates osteoarthritis development. J Pathol 239: 426-437. doi: 10.1002/path.4739. (査読有)

12. Iezaki T, Onishi Y, Ozaki K, Fukasawa K, Takahata Y, Nakamura Y, Fujikawa K, Takarada T, Yoneda Y, Yamashita Y, Shioi G, *Hinoi E. (2016) The Transcriptional Modulator Interferon-Related Developmental Regulator 1 in Osteoblasts Suppresses Bone Formation and Promotes Bone Resorption. J Bone Miner Res 31: 573-584. doi: 10.1002/jbmr.2720. (査読有)

13. Iezaki T, Fukasawa K, Park G, Horie T, Kanayama T, Ozaki K, Onishi Y, Takahata Y, Nakamura Y, Takarada T, Yoneda Y, Nakamura T, Vacher J, *Hinoi E. (2016) Transcriptional Modulator Ifrd1 Regulates Osteoclast Differentiation through Enhancing the NF-kappaB/NFATc1 Pathway. Mol Cell Biol 36: 2451-2463. doi: 10.1128/MCB.01075-15. (査読有)

14. Fukasawa K, Park G, Iezaki T, Horie T, Kanayama T, Ozaki K, Onishi Y, Takahata Y, Yoneda Y, Takarada T, Kitajima S, Vacher J, *Hinoi E. (2016) ATF3 controls proliferation of osteoclast precursor and bone remodeling. Sci Rep 6: 30918. doi: 10.1038/srep30918. (査読有)

15. Wei J, Shimazu J, Makinistoglu MP, Maurizi A, Kajimura D, Zong H, Takarada T, Iezaki T, Pessin JE, Hinoi E, *Karsenty G. (2015) Glucose Uptake and Runx2 Synergize to Orchestrate Osteoblast Differentiation and Bone Formation. Cell 161: 1576-1591. doi: 10.1016/j.cell.2015.05.029. (査読有)

16. Takarada T, Nakamichi N, Kakuda T, Nakazato R, Kokubo H, Ikeno S, Nakamura S, Hinoi E, *Yoneda Y. (2015) Daily oral intake of theanine prevents the decline of 5-bromo-2'-deoxyuridine incorporation in hippocampal dentate gyrus with concomitant alleviation of behavioral abnormalities in adult mice with severe traumatic stress. J Pharmacol Sci 127: 292-297. doi: 10.1016/j.jphs.2014.12.018. (査読有)

17. Nakazato R, Takarada T, Ikeno S, Nakamura S, Kutsukake T, Hinoi E, *Yoneda Y. (2015) Upregulation of Runt-Related Transcription Factor-2 Through CCAAT Enhancer Binding Protein-beta Signaling Pathway in Microglial BV-2 Cells Exposed to ATP. J Cell Physiol 230: 2510-2521. doi: 10.1002/jcp.24988. (査読有)

18. Fujikawa K, Fukumori R, Nakamura S, Kutsukake T, Takarada T, *Yoneda Y. (2015) Potential interactions of calcium-sensitive reagents with zinc ion in different cultured cells. PLoS One 10: e0127421. doi: 10.1371/journal.pone.0127421. (査読有)

19. Nakazato R, Takarada T, Watanabe T, Nguyen BT, Ikeno S, Hinoi E, *Yoneda Y. (2014) Constitutive and functional expression of runt-related transcription factor-2 by microglial cells. Neurochem Int 74: 24-35. doi: 10.1016/j.neuint.2014.04.010. (査読有)

1. Katayama K, Nonaka Y, Tsutsui K, Imai H, *KandoriH. (2017) Spectral Tuning Mechanism of Primate Blue-Sensitive Visual Pigment Elucidated by FTIR Spectroscopy. Sci Rep 7: 4904. doi: 10.1038/s41598-017-05177-4. (査読有)

2. Purba LHP, Widayati KA, Tsutsui K, Suzuki-Hashido N, Hayakawa T, Nila S, Suryobroto B, *Imai H. (2017) Functional characterization of the TAS2R38 bitter taste receptor for phenylthiocarbamide in colobine monkeys. Biol Lett 13: 20160834. doi: 10.1098/rsbl.2016.0834. (査読有)

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4. Tsutsui K, Otoh M, Sakurai K, Suzuki-Hashido N, Hayakawa T, Misaka T, Ishimaru Y, Aureli, F, Melin AD, *Kawamura S, *Imai H. (2016) Variation in ligand responses of the bitter taste receptors TAS2R1 and TAS2R4 among New World monkeys. BMC Evol Biol 16: 208. doi: 10.1186/s12862-016-0783-0. (査読有)

5. *Imai H, Suzuki-Hashido N, Ishimaru Y, Sakurai T, Yin L, Pan W, Ishiguro M, Masuda K, Abe K, Misaka T, Hirai H. (2016) Amino acid residues of bitter taste receptor TAS2R16 that determine sensitivity in primates to β-glycosides. Biophys Physicobiol 13: 165-171. doi: 10.2142/biophysico.13.0_165. (査読有)

6. Suzuki-Hashido N, Hayakawa T, Matsui A, Go Y, Ishimaru Y, Misaka T, Abe K, Hirai H, *Satta Y, *Imai H. (2015) Rapid expansion of phenylthiocarbamide non-tasters among Japanese macaques. PLoS One 10: e0132016. doi: 10.1371/journal.pone.0132016. (査読有)

1. Kato J, Takai Y, Hayashi MK, Kato Y, Tanaka M, Sohma Y, Abe Y, Yasui M. (2014) Expression and localization of aquaporin-4 in sensory ganglia. Biochem Biophys Res Commun 451: 562-567. doi: 10.1016/j.bbrc.2014.08.026. (査読有)

1. Imamaki R. Ogawa K, Kizuka Y, Komi Y, Kojima S, Kotani N, Honke K, Honda T, Taniguchi N, *Kitazume S. (2018) Glycosylation controls cooperative PECAM-VEGFR2-β3 integrin functions at the endothelial surface for tumor angiogenesis. Oncogene 37: 4287-4299. doi: 10.1038/s41388-018-0271-7. (査読有)

2. Iijima J, Kobayashi S, *Kitazume S, Kizuka Y, Fujinawa R, Korekane H, Shibata T, Saitoh S, Akashi-Takamura S, Miyake K, Miyoshi E, *Taniguchi N. (2017) Core fucose is critical for CD14-dependent Toll-like receptor 4 signaling. Glycobiology 27: 1006-1015. doi: 10.1093/glycob/cwx075. (査読有)

3. Sakuda K, Kizuka Y, Yamaguchi Y, Tanaka K, Ogiwara K, Segawa T, Hagiwara Y, Matsuo I, Ogawa H, Taniguchi N, *Kitazume S. (2017) Reactivity of anti-HNK-1 antibodies to branched O-mannose glycans associated with demyelination. Biochem Biophys Res Commun 487: 450-456. doi: 10.1016/j.bbrc.2017.04.085. (査読有)

4. Kizuka Y, Kitazume S, *Taniguchi N. (2017) N-glycan and Alzheimer's disease. Biochim Biophys Acta 1861: 2447-2454. doi: 10.1016/j.bbagen.2017.04.012. (査読有)

5. *Taniguchi N, *Takahashi M, Kizuka Y, Kitazume S. (2016) Glycation vs. Glycosylation: a tale of two different chemistries and biology in Alzheimer's disease. Glycoconjugate 33: 487-497. doi: 10.1007/s10719-016-9690-2. (査読有)

1. Nishimura K, Ishikawa S, Matsunami E, Yamauchi J, Homma K, Faulker C, Oparka K, Jisaka M, Nagaya T, Yokota K, Nakagawa T. (2015) New Gateway compatible vectors for a high-throughput protein-protein interaction analysis by a bimolecular fluorescence complementation (BiFC) assay and their application to an Arabidopsis clathrin structure analysis. Biosci Biotech Biochem 79: 1995-2006. doi: 10.1080/09168451.2015.1060847. (査読有)

2. Miyamoto Y, Torii T, Takada S, Ohno N, Saitoh Y, Nakamura K, Ito A, Ogata T, Terada N, Tanoue A, *Yamauchi J. (2015) Involvement of the Tyro3 receptor and its intracellular partner Fyn signaling in Schwann cell myelination. Mol Biol Cell 26: 3489-3503. doi: 10.1091/mbc.E14-05-1020. (査読有)

3. Torii T, Miyamoto Y, Yamamoto M, Ohbuchi K, Tsumura H, Kawahara K, Tanoue A, Sakagami H, *Yamauchi J. (2015) Data supporting Arf6 regulation of Schwann cell differentiation and myelination. Data Brief 5: 388-395. doi: 10.1016/j.dib.2015.09.025. (査読有)

4. Torii T, Miyamoto Y, Yamamoto M, Ohbuchi K, Tsumura H, Kawahara K, Tanoue A, Sakagami H, *Yamauchi J. (2015) Arf6 mediates Schwann cell differentiation and myelination. Biochem Biophys Res Commun 465: 450-457. doi: 10.1016/j.bbrc.2015.08.038. (査読有)

5. Miyamoto Y, Eguchi T, Kawahara K, Hasegawa N, Nakamura K, Funakoshi-Tago M, Tanoue A, Tamura H, *Yamauchi J. (2015) Hypomyelinating leukodystrophy-associated missense mutation in HSPD1 blunts mitochondrial dynamics. Biochem Biophys Res Commun 462: 275–281. doi: 10.1016/j.bbrc.2015.04.132. (査読有)

6. Torii T, Ohno N, Miyamoto Y, Kawahara K, Saitoh Y, Nakamura K, Takashima S, Sakagami H, Tanoue A, *Yamauchi J. (2015) Arf6 guanine-nucleotide exchange factor cytohesin-2 regulates myelination in nerves. Biochem Biophys Res Commun 460: 819-825. doi: 10.1016/j.bbrc.2015.03.113. (査読有)

7. Nakamura K, Nakabayashi K, Kyaw Htet Aung, Aizawa K, Hori N, Yamauchi J, Hata K, Tanoue A. (2015) DNA methyltransferase inhibitor zebularine induces human cholangiocarcinoma cell death through alteration of DNA methylation status. PLoS One 10: e0120545. doi: 10.1371/journal.pone.0120545. (査読有)

8. Tezuka Y, Herai N, Inomata Y, Kagami K, Yamauchi J, Nishigori H, Sanbe A. (2015) Upregulation of inorganic pyrophosphatase 1 as a JNK phosphatase in hypothyroid embryonic chick cerebellum. Life Sci 128: 94–100. doi: 10.1016/j.lfs.2015.02.019. (査読有)

9. *Torii T, Miyamoto Y, Tago K, Sango K, Nakamura K, Sanbe A, Tanoue A, *Yamauchi J. (2014) Arf6 guanine-nucleotide exchange factor cytohesin-2 binds to CCDC120 and is transported along neurites to mediate neurite growth. J Biol Chem 289: 33887-33903. doi: 10.1074/jbc.M114.575787. (査読有)

10. Torii T, Miyamoto Y, Takada S, Tsumura H, Arai M, Nakamura K, Ohbuchi K, Yamamoto M, Tanoue A, *Yamauchi J. (2014) In vivo knockdown of ErbB3 in mice inhibits Schwann cell precursor migration. Biochem Biophys Res Commun 452: 782-788. doi: 10.1016/j.bbrc.2014.08.156. (査読有)

11. Miyamoto Y, Eguchi T, Torii T, Nakamura K, Tanoue A, and *Yamauchi J. (2014) Hypomyelinating leukodystrophy-associated missense mutant of FAM126A/hyccin/DRCTNNB1A aggregates in the endoplasmic reticulum. J Clin Neurosci 21: 1033-1039. doi: 10.1016/j.jocn.2013.09.014. (査読有)

12. Miyamoto Y, Yamamori N, Torii T, Tanoue A, *Yamauchi J. (2014) Rab35, acting through ACAP2 switching off Arf6, negatively regulates oligodendrocyte differentiation and myelination. Mol Biol Cell 25: 1532-1542. doi: 10.1091/mbc.E13-10-0600. (査読有)

1. Ikeda M, Shimasaki A, Takahashi A, Kondo K, Saito T, Kawase K, Esaki K, Otsuka Y, Mano K, Kubo M, *Iwata N. (2016). Genome-wide environment interaction between depressive state and stressful life events. J Clin Psychiatry 77: e29-30. doi: 10.4088/JCP.15l10127. (査読有)

2. Saito T, Ikeda M, Mushiroda T, Ozeki T, Kondo K, Shimasaki A, Kawase K, Hashimoto S, Yamamori H, Yasuda Y, Fujimoto M, Ohi K, Takeda M, Kamatani Y, Numata S, Ohmori T, Ueno SI, Makinodan M, Nishihata Y, Kubota M, Kimura T, Kanahara N, Hashimoto N, Fujita K, Nemoto K, Fukao T, Suwa T, Noda T, Yada Y, Takaki M, Kida N, Otsuru T, Murakami M, Takahashi A, Kubo M, Hashimoto R, *Iwata N. (2016) Pharmacogenomic Study of Clozapine-Induced Agranulocytosis/Granulocytopenia in a Japanese Population. Biol Psychiatry 80: 636-642. doi: 10.1016/j.biopsych.2015.12.006. (査読有)

3. Hatano M, *Ikeda M, Kondo K, Saito T, Shimasaki A, Esaki K, Umene-Nakano W, Yoshimura R, Nakamura J, Ozaki N, Iwata N. (2015) No support for replication of the genetic variants identified by a recent mega-analysis of the treatment response to antidepressants. J Hum Genet 60: 343-344. doi: 10.1038/jhg.2015.21. (査読有)

1. *Tachikawa M, Toki H, Watanabe M, Tomi M, Hosoya K, Terasaki T. (2018) Gene expression of A6-like subgroup of ATP-binding cassette transporters in mouse brain parenchyma and microvessels. Anat Sci Int 93: 456-463. doi: 10.1007/s12565-018-0435-0. (査読有)

2. *Tachikawa M, Yokoyama R, Akanuma S, *Hosoya K. (2018) Assembly of Taurine Transporter (Slc6a6) with Na+-H+ Exchanger Regulatory Factor 1 (Slc9a3r1) Improves GABA Transport Activity by Increasing the Maximum Transport Velocity. Biol Pharm Bull 41: 338-341. doi: 10.1248/bpb.b17-00664. (査読有)

1. Komine O, Yamashita H, Fujimori-Tonou N, Koike M, Jin S, Moriwaki Y, Endo F, Watanabe S, Uematsu S, Akira S, Uchiyama Y, Takahashi R, Misawa H, *Yamanaka K. (2018) Innate immune adaptor TRIF slows disease progression of ALS mice with accumulation of aberrantly activated astrocytes. Cell Death Differ 25: 2130-2146. doi: 10.1038/s41418-018-0098-3. (査読有)

2. *Yamanaka K, Komine O. (2018) The multi-dimensional roles of astrocytes in ALS. Neurosci Res 126: 31-38. doi: 10.1016/j.neures.2017.09.011. (査読有)

3. Endo F, Komine O, *Yamanaka K. (2016) Neuroinflammation in motor neuron disease. Clin Exp Neuroimmunol 7: 126-138. doi: 10.1111/cen3.12309. (査読有)

1. Okada R, Zhang X, Harada Y, Wu Z, *Nakanishi H. (2018) Cathepsin H deficiency in mice induces excess Th1 cell activation and early-onset of EAE through impairment of toll-like receptor 3 cascade. Inflamm Res 67: 371-374. doi: 10.1007/s00011-018-1136-9. (査読有)

2. Liu Y, Wu Z, Nakanishi Y, Ni J, Hayashi Y, Takayama F, Zhou Y, Kadowaki T,*Nakanishi H. (2017) Infection of microglia with Porphorymonas gingivalis promotes migration and inflammatory response through the gingipain-mediated activation of protease-activated receptor-2 in mice. Sci Rep 7: 11759. doi: 10.1038/s41598-017-12173-1. (査読有)

3. *Wu Z, Ni J, Liu Y, Teeling JL, Takayama F, Collcutt A, Ibbett P, Nakanishi H. (2017) Cathepsin B plays a critical role in inducing Alzheimer’s disease-like phenotypes following chronic systemic exposure to lipopolysaccharidefrom Porphyromonas gingivalis in mice. Behav Brain Immun 65: 350-361. doi: 10.2016/j.bbi.2017.06.002. (査読有)

4. Takayama F, Zhang X, Hayashi Y, Wu Z, *Nakanishi H. (2017) Dysfunction in diurnal synaptic responses and social behavior abnormalities in cathepsin S-deficient mice. Biochem Biophys Res Commun 490: 447-452. doi: 10.1016/j.bbrc.2017.06.061. (査読有)

5. Harada Y, Takayama F, Tanabe K, Ni J, Hayashu Y, Yamamoto K, Wu Z, *Nakanishi H. (2017) Overexpression of cathepsin E interferes with neuronal differentiation of P19 embryonal teratocarcinoma cells by degradation of N-cadherin. Cell Mol Neurobiol 37: 437-443. doi: 10.1007/s10571-016-0376-x. (査読有)

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