東京大学医科学研究所附属病院 エイズワクチン開発担当分野
国立感染症研究所 エイズ研究センター 第一研究グループ、第二研究グループ

英語論文  2021年以降  2016~2020年  2011~2015年  2006~2010年  2001~2005年  2000年以前

和文論文  2021年以降  2016~2020年  2011~2015年  2006~2010年  2001~2005年  2000年以前


英語論文(2021年以降)

Minh, T.T.T., Hikichi, Y., Miki, S., Imanari, Y., Kusagawa, S., Okazaki, M., Thao, D.T.T., Shiino, T., Matsuoka, S., Yamamoto, H., Ohashi, J., Hall, W.W., Matano, T., Thi, L.A.N.*, and Kawana-Tachikawa, A.* Protective role of HLA-B*57:01/58:01 is impaired in HIV-1 CRF01_AE infection in Vietnam. Int. J. Infect. Dis., in press.

Adachi, M.*, Taniguchi, K., Hori, H., Mizutani, T., Ishizaka, A., Ishikawa, K., Matano, T., Opare, D., Arhin, D., Asiedu, F.B., Ampofo, W.K., Yeboah, D.M., Koram, K.A., Anang, A.K., and Kiyono, H. Strengthening surveillance in Ghana against public health emergencies of international concern. Trop. Med. Health 50:81, 2022.

Terahara, K., Sato, T., Adachi, Y., Tonouchi, K., Onodera, T., Moriyama, S., Sun, L., Takano, T., Nishiyama, A., Kawana-Tachikawa, A., Matano, T., Matsumura, T., Shinkai, M., Isogawa, M.*, and Yoshimasa, T. SARS-CoV-2 specific T cell longevity correlates with disease severity. iScience 25:104959, 2022.

Ode, H.1, Saito, A.1, Washizaki, A.1, Seki, Y., Yoshida, T., Harada, S., Ishii, H., Shioda, T., Yasutomi, Y., Matano, T., Miura, T., Akari, H.*, and Iwatani, Y.* Development of a novel macaque-tropic HIV-1 adapted to cynomolgus macaques. J. Gen. Virol. 103, 2022. doi: 10.1099/jgv.0.001790.

Parbie, P.K., Abana, C.Z., Kushitor, D., Asigbee, T.W., Ntim, N.A.A., Addo-Tetebo, G., Ansong, M.R., Ofori, S.B., Mizutani, T., Runtuwene, L.R., Nishizawa, M., Ishikawa, K., Kiyono, H., Ampofo, W.K., Matano, T., Bonney, E.Y.*, and Kikuchi, T.* High-level resistance to non-nucleos(t)ide reverse transcriptase inhibitor based first-line antiretroviral therapy in Ghana; a 2017 study. Front. Microbiol. 13:973771, 2022.

Hau, T.T.T.1, Nishizawa, M.1, Harada, S., Phan, M.H., Kanno, Y., Nomura, T., Matsuoka, S., Kawana-Tachikawa, A., Hall, W.W., Matano, T., Nguyen, L.A.T., and Yamamoto, H.* Association of Envelope-specific B-cell differentiation and viral selective pressure signatures in HIV-1 CRF01_AE infection. AIDS 36:1629-1641, 2022.

Saso, W., Yamasaki, M., Nakakita, S., Fukushi, S., Tsuchimoto, K., Watanabe, N., Sriwilaijaroen, N., Kanie, O., Muramatsu, M., Takahashi, Y., Matano, T., Takeda, M., Suzuki, Y.*, and Koichi Watashi, W.* Significant role of host sialylated glycans in the infection and spread of severe acute respiratory syndrome coronavirus 2. PLoS Pathog. 18:e1010590, 2022.

Nii-Trebi, N.I., Matsuoka, S., Kawana-Tachikawa, A., Bonney, E.Y., Abana, C.Z., Ofori, S.B., Mizutani, T., Ishizaka, A., Shiino, T., Ohashi, J., Naruse, T.K., Kimura, A., Kiyono, H., Ishikawa, K., Ampofo, W.K.*, and Matano, T.* Super high-resolution single-molecule sequence-based typing of HLA class I alleles in HIV-1 infected individuals in Ghana. PLoS ONE 17:e0269390, 2022.

Afum, T., Asandem, D.A., Asare, P., Asante-Poku, A., Mensah, G.I., Musah, A.B., Opare, D., Taniguchi, K., Guinko, N.M., Aphour, T., Arhin, D., Ishikawa, K., Matano, T., Mizutani, T., Bekoe, F.A., Kiyono, H., Anang, A.K., Koram, K.A., and Yeboah-Manu, D.* Diarrhea-causing bacteria and their antibiotic resistance patterns among diarrhea patients from Ghana. Front. Microbiol. 13:894319, 2022.

Asante, N.N.A., Ishii, H., Jomori, M., Yamamoto, H., Matano, T., and Nomura, T.* Hierarchy of multiple viral CD8+ T-cell epitope mutations in sequential selection in simian immunodeficiency infection. Biochem. Biophys. Res. Commun., 607:124-130, 2022.

Ishii, H.1, Nakamura-Hoshi, M.1, Shu, T., and Matano, T.* Sendai virus particles carrying target virus glycoproteins for antibody induction. Vaccine 40:2420-2431, 2022.

Ishii, H., Terahara, K., Nomura, T., Okazaki, M., Yamamoto, H., Shu, T., Sakawaki, H., Miura, T., Watkins, D.I., and Matano, T.* Env-independent protection of intrarectal SIV challenge by vaccine induction of Gag/Vif-specific CD8+ T cells but not CD4+ T cells. Mol. Ther. 30:2048-2057, 2022.

Mizutani, T.*, Ishizaka, A., Koga, M., Ikeuchi, K., Saito, M., Adachi, E., Yamayoshi, S., Iwatsuki-Horimoto, K., Yasuhara, A., Kiyono, H., Matano, T., Suzuki, Y., Tsutsumi, T., Kawaoka, Y., and Yotsuyanagi, H. Correlation analysis between gut microbiota alterations and the cytokine response in patients with coronavirus disease during hospitalisation. Microbiol. Spectr. 10:e0168921, 2022.

Miki, S., Kawai, Y., Nakayama-Hosoya, K., Iwabuchi, R., Terahara, K., Tsunetsugu-Yokota, Y., Koga, M., Matano, T., Kaneko, S., and Kawana-Tachikawa, A.* Sustainable antiviral efficacy of rejuvenated HIV-specific cytotoxic T lymphocytes generated from induced pluripotent stem cells. J. Virol. 96:e0221721, 2022.

Ishii, H.1, Nomura, T.1, Yamamoto, H., Nishizawa, M., Hau, T.T.T., Harada, S., Seki, S., Nakamura-Hoshi, M., Okazaki, M., Daigen, S., Kawana-Tachikawa, A., Nagata, N., Iwata-Yoshikawa, N., Shiwa, N., Suzuki, T., Park, E.S., Maeda, K., Onodera, T., Takahashi, Y., Kusano, K., Shimazaki, R., Suzaki, Y., Ami, Y., and Matano, T.* Neutralizing antibody-independent SARS-CoV-2 control correlated with intranasal vaccine-induced CD8+ T-cell responses. Cell Rep. Med. 3:100520, 2022.

Matsuoka, S.*, Adusei-Poku, M.A., Abana, C.Z., Duker, E.O., Bonney, E.Y., Ofori, S.B., Parbie, P.K., Okazaki, M., Kawana-Tachikawa, A., Ishikawa, K., Ampofo, W.A., and Matano, T. Asessment of the proportion of recent HIV-1 infections in newly-diagnosed cases in Ghana. Jpn. J. Infect. Dis. 75:395-397, 2022.

Koga, M., Senkoji, T., Kubota, M., Ishizaka, A., Mizutani, T., Sedohara, A., Ikeuchi, K., Kikuchi, T., Adachi, E., Saito, M., Koibuchi, T., Hosomichi, K., Ohashi, J., Kawana-Tachikawa, A., Matano, T., Tsutsumi, T.*, and Yotsuyanagi, H. Predictors associated with a better response to the Japanese aluminum-free hepatitis A vaccine, Aimmugen, for people living with HIV. Hepatol Res, in press.

Hau, T.T.T., Kanno, Y., Nishizawa, M., Nomura, T., Matano, T., and Yamamoto, H.* Nef-specific CD107a+ CD4+ T-cell responses in a rhesus macaque (Macaca mulatta) showing partial simian immunodeficiency virus control following passive neutralizing antibody infusion. J. Med. Primatol. 51:56-61, 2022.

Ishizaka, A., Koga, M., Mizutani, T.*, Lim, L.A., Adachi, E., Ikeuchi, K., Ueda, R., Aoyagi, H., Tanaka, S., Kiyono, H., Matano, T., Aizaki, H., Yoshio, S., Mita, E., Muramatsu, M., Kanto, T., Tsutsumi, T., and Yotsuyanagi, H.* Prolonged gut dysbiosis and fecal excretion of hepatitis A virus in patients infected with human immunodeficiency virus. Viruses 13:2101, 2021.

Ishizaka, A., Koga, M., Mizutani, T.*, Parbie, P., Prawisuda, D., Yusa, N., Sedohara, A., Kikuchi, T., Ikeuchi, K., Adachi, E., Koibuchi, T., Furukawa, Y., Tojo, A., Imoto, S., Suzuki, Y., Tsutsumi, T., Kiyono, H., Matano, T., and Yotsuyanagi, H. Unique gut microbiome in HIV patients on ART suggests association with chronic inflammation. Microbiol. Spectr. 9:e0070821, 2021.

Nomura, T., Yamamoto, H., Nishizawa, M., Hau, T.T.T., Harada, S., Ishii, H., Seki, S., Nakamura-Hoshi, M., Okazaki, M., Daigen, S., Kawana-Tachikawa, A., Nagata, N., Iwata-Yoshikawa, N., Shiwa, N., Iida, S., Katano, H., Suzuki, T., Park, E.S., Maeda, K., Suzaki, Y., Ami, Y., and Matano, T.* Subacute SARS-CoV-2 replication can be controlled in the absence of CD8+ T cells in cynomolgus macaques. PLoS Pathog. 17:e1009668, 2021.

Miki, S., Sasaki, H.*, Horiuchi, H., Miyata, N., Yoshimura, Y., Miyazaki, K., Matsumura, T., Takahashi, Y., Suzuki, T., Matano, T., Kawana-Tachikawa, A., and Tachikawa, N. On-admission SARS-CoV-2 RNAemia as a single potent predictive marker of critical condition development and mortality in COVID-19. PLoS ONE 16:e0254640, 2021.

Kanno, Y., Hau, T.T.T., Kurokawa, R., Nomura, T., Nishizawa, M., Matano, T., and Yamamoto, H.* Late-phase dominance of a single epitope-specific CD8+ T-cell response in passive neutralizing antibody-infused SIV controllers. AIDS 35:2281-2288, 2021.

Mizutani, T.*, Aboagye, S.Y., Ishizaka, A., Afum, T., Mensah, G.I., Asante-Poku, A., Asandem, D.A., Parbie, P.K., Abana, C.Z., Kushitor, D., Adachi, M., Hori, H., Ishikawa, K., Matano, T., Taniguchi, K., Opare, D., Doris, A., Asiedu-Bekoe, F., Ampofo, W.K., Yeboah-Manu, D., Koram, K.A., Anang, A.K., and Kiyono, H. Gut microbiota signature of pathogen-dependent dysbiosis in viral gastroenteritis. Sci. Rep. 11:13945, 2021.

Moriyama, S.1, Adachi, Y.1, Sato, T., Tonouchi, K., Sun, L., Fukushi, S., Yamada, S., Kinoshita, H., Nojima, K., Kanno, T., Tobiume, M., Ishijima, K., Kuroda, Y., Eunsil, P., Onodera, T., Matsumura, T., Takano, T., Terahara, K., Isogawa, M., Nishiyama, A., Kawana-Tachikawa, A., Shinkai, M., Tachikawa, N., Nakamura, S., Okai, T., Okuma, K., Matano, T., Fujimoto, T., Maeda, K., Ohnishi, M., Wakita, T., Suzuki, T., and Takahashi, Y.* Temporal maturation of neutralizing antibodies in COVID-19 convalescent individuals improves potency and breadth to circulating SARS-CoV-2 variants. Immunity 54:1841-1852.e4, 2021.

Nomura, Y., Matsuoka, S., Okazaki, M., Kuwata, T., Matano, T., and Ishii, H.* Neutralizing antibody induction associated with a germline immunoglobulin gene polymorphism in neutralization-resistant SIVsmE543-3 infection. Viruses 13:1181, 2021.

Otani, M., Shiino, T.*, Kondo, M., Hachiya, A., Nishizawa, M., Kikuchi, T., Matano, T., and Japanese Drug Resistance HIV-1 Surveillance Network. Phylodynamic analysis reveals changing transmission dynamics of HIV-1 CRF01_AE in Japan from heterosexuals to men who have sex with men. Int. J. Infect. Dis. 108:397-405, 2021.

Parbie, P.K., Mizutani, T., Ishizaka, A., Kawana-Tachikawa, A., Runtuwene, L.R., Seki, S., Abana, C.Z., Kushitor, D., Bonney, E.Y., Ofori, S.B., Uematsu, S., Imoto, S., Kimura, Y., Kiyono, H., Ishikawa, K., Ampofo, W.K.*, and Matano, T.* Dysbiotic fecal microbiome in HIV-1 infected individuals in Ghana. Front. Cell. Infect. Microbiol. 11:646467, 2021.

Ohashi, H.1, Watashi, K.1*, Saso, W.1, Shionoya, K., Iwanami, S., Hirokawa, T., Shirai, T., Kanaya, S., Ito, Y., Kim, K.S., Nomura, T., Suzuki, T., Nishioka, K., Ando, S., Ejima, K., Koizumi, Y., Tanaka, T., Aoki, S., Kuramochi, K., Suzuki, T., Hashiguchi, T., Maenaka, K., Matano, T., Muramatsu, M., Saijo, M., Aihara, K., Iwami, S., Takeda, M., McKeating, J.A., Wakita, T. Potential anti-COVID-19 agents, Cepharanthine and Nelfinavir, and usage for combination treatment. iScience 24:102367, 2021.

Anzurez, A., Naka, I., Miki, S., Hosoya-Nakayama, K., Isshiki, M., Watanabe, Y., Nakamura-Hoshi, M., Seki, S., Matsumura, T., Takano, T., Onodera, T., Adachi, Y., Moriyama, S., Terahara, K., Tachikawa, N., Yoshimura, Y., Sasaki, H., Horiuchi, H., Miyata, N., Miyazaki, K., Koga, M., Ikeuchi, K., Nagai, H., Saito, M., Adachi, E., Yotsuyanagi, H., Kutsuna, S., Kawashima, A., Miyazato, Y., Kinoshita, N., Kouno, C., Tanaka, K., Takahashi, Y., Suzuki, T., Matano, T., Ohashi, J.*, and Kawana-Tachikawa, A.* Association of Human Leukocyte Antigen DRB1*09:01 with severe COVID-19. HLA 98:37-42, 2021.

Takano, T., Matsumura, T.*, Adachi, Y., Terahara, K., Moriyama, S., Onodera, T., Nishiyama, A., Kawana-Tachikawa, A., Miki, S., Hosoya-Nakayama, K., Nakamura-Hoshi, M., Seki, S., Tachikawa, N., Yoshimura, Y., Miyata, N., Horiuchi, H., Sasaki, H., Miyazaki, K., Kinoshita, N., Sudo, T., Akiyama, Y., Sato, R., Suzuki, T., Matano, T., and Takahashi, Y.* Myeloid cell dynamics correlating with clinical outcomes of severe COVID-19 in Japan. Int. Immunol. 33:241-247, 2021.

Matsuoka, S.1, Kuwata, T.1*, Ishii, H.1, Sekizuka, T., Kuroda, M., Sano, M., Okazaki, M., Yamamoto, H., Shimizu, M., Matsushita, S., Seki, Y., Saito, A., Sakawaki, H., Hirsch, V.M., Miura, T., Akari, H., and Matano, T.* A potent anti-simian immunodeficiency virus neutralizing antibody induction associated with a germline immunoglobulin gene polymorphism in rhesus macaques. J. Virol. 95:e02455-20, 2021.

Baumeister, W., Carafoli, E., and Matano, T. (Ed.) The COVID-19 Pandemic. Biochem. Biophys. Res. Commun. 538 (Special Issue):1-258, 2021.

Tanimoto, K., Naruse, T.K., Matano, T., and Kimura, A.* Development and evaluation of a rapid and cost-efficient NGS-based MHC class I genotyping method for macaques by using a prevalent short-read sequencer. Immunogenetics 73:175-186, 2021.

Sato, H., Ota, Y., Kido, Y., Matsumoto, T., Matsubara, Y., Matano, T., Hirata, Y., Kawana-Tachikawa, A., Yamaoka, Y., Yotsuyanagi, H., and Adachi, E. Gut-homing CD4+ T cells are associated with the activity of gastritis in HIV-infected adults. AIDS Res. Hum. Retroviruses 36:910-917, 2020.

Pomplun, N.L., Vosler, L., Weisgrau, K.L., Furlott, J., Weiler, A.M., Abdelaal, H.M., Evans, D.T., Watkins, D.I., Matano, T., Skinner, P.J., Friedrich, T.C., and Rakasz, E.G.* Immunophenotyping of rhesus CMV-specific CD8 T cell populations. Cytometry A 99:278-288, 2021.

Parbie, P.K., Mizutani, T., Ishizaka, A., Kawana-Tachikawa, A., Runtuwene, L.R., Seki, S., Abana, C.Z., Kushitor, D., Bonney, E.Y., Ofori, S.B., Uematsu, S., Imoto, S., Kimura, Y., Kiyono, H., Ishikawa, K., Ampofo, W.K., and Matano, T.* Fecal microbiome composition in healthy adults in Ghana. Jpn. J. Infect. Dis. 74:42-47, 2021.

英語論文(2016~2020年)  ペー ジトップへ戻る

Sato, H., Ota, Y., Kido, Y., Matsumoto, T., Matsubara, Y., Matano, T., Hirata, Y., Kawana-Tachikawa, A., Yamaoka, Y., Yotsuyanagi, H., and Adachi, E. Gut-homing CD4+ T cells are associated with the activity of gastritis in HIV-infected adults. AIDS Res. Hum. Retroviruses 36:910-917, 2020.

Nakamura-Hoshi, M., Takahara, Y., Matsuoka, S., Ishii, H., Seki, S., Nomura, T., Yamamoto, H., Sakawaki, H., Miura, T., Tokusumi, T., Shu, T., and Matano, T.* Therapeutic vaccine-mediated Gag-specific CD8+ T-cell induction under anti-retroviral therapy augments anti-virus efficacy of CD8+ cells in simian immunodeficiency virus-infected macaques. Sci. Rep. 10:11394, 2020.

Yamamoto, H., Ishii, H., and Matano, T.* Mucosal vaccines against HIV/SIV infection. Mucosal Vaccines, 2nd Ed. (Ed.: Kiyono, H. and Pascual, D.W.), Academic Press, Chapter 42, p.713-722, 2020.

Ishii, H., Terahara, K., Nomura, T., Takeda, A., Okazaki, M., Yamamoto, H., Tokusumi, T., Shu, T., and Matano, T.* A novel immunogen selectively eliciting CD8+ T cells but not CD4+ T cells targeting immunodeficiency virus antigens. J. Virol. 94:e01876-19, 2020.

Nakamura-Hoshi, M., Suzuki, T., Ainai, A., Hasegawa, H., Ishii, H., and Matano, T.* Inefficient Tax-specific T-cell responses in mice after syngeneic transplantation with tax-transgenic mouse-derived adult T-cell leukemia cells. Jpn. J. Infect. Dis. 73:221-225, 2020.

Iwamoto, M.1, Saso, W.1, Nishioka, K., Ohashi, H., Sugiyama, R., Ryo, A., Ohki, M., Yun, J.H., Park, S.Y., Ohshima, T., Suzuki, R., Aizaki, H., Muramatsu, M., Matano, T., Iwami, S., Sureau, C., Wakita, T., and Watashi, K.* The machinery for endocytosis of epidermal growth factor receptor coordinates the transport of incoming hepatitis B virus to the endosomal network. J. Biol. Chem. 295:800-807, 2020.

Ishii, H.1, Matsuoka, S.1, Ikeda, N., Kurihara, K., Ueno, T., Takiguchi, M., Naruse, T.K., Kimura, A., Yokoyama, M., Sato, H., and Matano, T.* Determination of a T cell receptor of potent CD8+ T cells against simian immunodeficiency virus infection in Burmese rhesus macaques. Biochem. Biophys. Res. Commun. 521:894-899, 2020.

Matsuoka, S., Nagashima, M., Sadamasu, K., Mori, H., Kawahata, T., Zaitsu, S., Nakamura, A., de Souza, M.S., and Matano, T.* Estimating HIV-1 incidence in Japan from the proportion of recent infections. Prev. Med. Rep. 16:100994, 2019.

Adusei-Poku, M.A., Matsuoka, S., Bonney, E.Y., Abana, C.Z., Duker, E.O., Nii-Trebi, N.I., Ofori, S.B., Mizutani, T., Ishizaka, A., Shiino, T., Kawana-Tachikawa, A., Ishikawa, K., Ampofo, W.K., and Matano, T.* Human leukocyte antigen-associated HIV-1 CRF02_AG gag and vif polymorphisms in Ghana. Jpn. J. Infect. Dis. 72:374-380, 2019.

Hikichi, Y.1, Takeda, E.1, Fujino, M., Nakayama, E., Matano, T., and Murakami, T.* HIV-1 matrix mutations that alter Gag membrane binding modulate mature core formation and post-entry events. Virology 532:97-107, 2019.

Hau, T.T.T.1, Nakamura-Hoshi, M.1, Kanno, Y., Nomura, T., Nishizawa, M., Seki, S., Ishii, H., Kawana-Tachikawa, A., Hall, W.W., Nguyen, L.A.T.*, Matano, T.*, and Yamamoto, H.* CD8+ T cell-based strong selective pressure on multiple simian immunodeficiency virus targets in macaques possessing a protective MHC class I haplotype. Biochem. Biophys. Res. Commun. 512:213-217, 2019.

Tsukamoto, T.*, Yamamoto, H., and Matano, T. CD8+ cytotoxic T lymphocyte breadth could facilitate early immune detection of immunodeficiency virus-derived epitopes with limited expression levels. mSphere 4:e00381-18, 2019.

Naruse, T.K., Akari, H., Matano, T., and Kimura, A.* Diversity of ULBP5 in the Old World monkey (Cercopithecidae) and divergence of ULBP gene family in primates. Proc. Jpn. Acad. Ser. B Phys. Biol. Sci. 94:441-453, 2018.

Takahashi, N.1, Matsuoka S.1, Minh, T.T.T., Ba, H.P., Naruse, T.K., Kimura, A., Shiino, T., Kawana-Tachikawa, A., Ishikawa, K., Matano, T.*, and Thi, L.A.N.* Human leukocyte antigen-associated gag and nef polymorphisms in HIV-1 subtype A/E-infected individuals in Vietnam. Microbes Infect. 21:113-118, 2019.

Kato, H., Kanou, K., Arima, Y.*, Ando, F., Matsuoka, S., Yoshimura, K., Matano, T., Matsui, T., Sunagawa, T., and Oishi, K. The importance of accounting for testing and positivity in surveillance by time and place: an illustration from HIV surveillance in Japan. Epidemiol. Infect. 146:2072-2078, 2018.

Saso, W., Tsukuda, S., Ohashi, H., Fukano, K., Morishita, R., Matsunaga, S., Ohki, M., Ryo, A., Park, S.-Y., Suzuki, R., Aizaki, H., Muramatsu, M., Sureau, C., Wakita, T., Matano, T., and Watashi, K.* A new strategy to identify hepatitis B virus entry inhibitors by AlphaScreen technology targeting the envelope-receptor interaction. Biochem. Biophys. Res. Commun. 501:374-379, 2018.

Ono, T., Fujita, Y., Matano, T., Takahashi, S., Morio, T., and Kawana-Tachikawa, A.* Characterization of in vitro expanded virus-specific T cells toward adoptive immunotherapy against virus infection. Jpn. J. Infect. Dis. 71:122-128, 2018.

Nii-Trebi, N.I., Brandful, J.A.M., Ibe, S., Sugiura, W., Barnor, J.S., Bampoe, P., Yamaoka, S., Matano, T., Yoshimura, K., Ishikawa, K., and Ampofo, W.K.* Dynamic HIV-1 genetic recombination and genotypic drug resistance among treatment-experienced adults in northern Ghana. J. Med. Microbiol. 66:1663-1672, 2017.

Seki, S.1, Nomura, T.1, Nishizawa, M.1, Yamamoto, H., Ishii, H., Matsuoka, S., Shiino, T., Sato, H., Mizuta, K., Sakawaki, H., Miura, T., Naruse, T.K., Kimura, A., and Matano, T.* In vivo virulence of MHC-adapted AIDS virus serially-passaged through MHC-mismatched hosts. PLoS Pathog. 13:e1006638, 2017.

Nyombayire, J., Anzala, O., Gazzard, B., Karita, E., Bergin, P., Hayes, P., Kopycinski, J., Omosa-Manyonyi, G., Jackson, A., Bizimana, J., Farah, B., Sayeed, E., Parks, C.L., Inoue, M., Hironaka, T., Hara, H., Shu, T., Matano, T., Dally, L., Barin, B., Park, H., Gilmour, J., Lombardo, A., Excler, J.-L., Fast, P., Laufer, D.S., Cox, J.H.*, and the S001 Study Team. First-in-human evaluation of the safety and immunogenicity of an intranasally administered replication-competent Sendai virus-vectored HIV type 1 Gag vaccine: induction of potent T-cell or antibody responses in prime-boost regimens. J. Infect. Dis. 215:95-104, 2017.

Yamamoto, H.*, and Matano, T. Patterns of HIV/SIV prevention and control by passive antibody immunization. Front. Micobiol. 7:1739, 2016.

Sakai, K., Ami, Y., Suzaki, Y., and Matano, T.* First complete genome sequence of a simian foamy virus isolate from a cynomolgus macaque. Genome Announc. 4:e01332-16, 2016.

Yamamoto, H.*, Iseda, S., Nakane, T., Nomura, T., Takahashi, N., Seki, S., Nakamura, M., Ishii, H., and Matano, T. Augmentation of anti-SIV activity in CD8+ cells by neutralizing but not non-neutralizing antibodies in the acute phase. AIDS 30:2391-2394, 2016.

Hikichi, Y., Yokoyama, M., Takemura, T., Fujino, M., Kumakura, S., Maeda, Y., Yamamoto, N., Sato, H., Matano, T., and Murakami, T.* Increased HIV-1 sensitivity to neutralizing antibodies by mutations in the Env V3-coding region for resistance to CXCR4 antagonists. J. Gen. Virol. 97:2427-2440, 2016.

Tsukamoto, T.*, Yamamoto, H., Okada, S., and Matano, T.* Recursion-based depletion of human immunodeficiency virus-specific naïve CD4+ T cells may facilitate persistent viral replication and chronic viraemia leading to acquired immunodeficiency syndrome. Med. Hypotheses 94:81-85, 2016.

Ishii, H., Matsuoka, S., Nomura, T., Nakamura, M., Shiino, T., Sato, Y., Iwata-Yoshikawa, N., Hasegawa, H., Mizuta, K., Sakawaki, H., Miura, T., Koyanagi, Y., Naruse, T.K., Kimura, A., and Matano, T. Association of lymph-node antigens with lower Gag-specific central-memory and higher Env-specific effector-memory CD8+ T-cell frequencies in a macaque AIDS model. Sci. Rep. 6:30153, 2016.

Iseda, S.1, Takahashi, N.1, Poplimont, H.1, Nomura, T., Seki, S., Nakane, T., Nakamura, M., Shi, S., Ishii, H., Furukawa, S., Harada, S., Naruse, T.K., Kimura, A., Matano, T., and Yamamoto, H*. Biphasic CD8+ T-cell defense in simian immunodeficiency virus control by acute-phase passive neutralizing antibody immunization. J. Virol. 90:6276-6290, 2016.

Seki, S., and Matano, T.* Development of a Sendai virus vector-based AIDS vaccine inducing T cell responses. Exp. Rev. Vaccines 15:119-127, 2016.

英語論文(2011~2015年)     ペー ジトップへ戻る

Nomura, T., Yamamoto, H., Ishii, H., Akari, H., Naruse, T.K., Kimura, A., and Matano, T. Broadening of virus-specific CD8+ T-cell responses is indicative of residual viral replication in aviremic SIV controllers. PLoS Pathog. 11:e1005247, 2015.

Nishizawa, M., Matsuda, M., Hattori, J., Shiino, T., Matano, T., and Sugiura, W. Longitudinal detection and persistence of minority drug-resistant populations and their effect on salvage therapy. PLoS ONE 10:e0135941, 2015.

Ishii, H., and Matano, T. Development of an AIDS vaccine using Sendai virus vectors. Vaccine 33:6061-6065, 2015.

Kusagawa, S., Yokota, Y., Negishi, M., Kondo, M., Matano, T., Kato, S., and Takebe, Y. Novel HIV-1 recombinant identified in a foreign heterosexual resident in Japan: relatedness to recently reported CRF69_01B, detected primarily among Japanese men who have sex with men. Genome Announc. 3:e00196-15, 2015.

Matano, T., Terahara, K., Ishii, H., and Nomura, T. Vaccine-induced CD107a+ CD4+ T-cells are resistant to killing following immunodeficiency virus infection. AIDS Res. Hum. Retroviruses 30 Suppl. 1:A247, Oct. 2014.

Karita, E., Anzala, O., Gazzard, B., Bergin, P., Nyombayire, J., Omosa, G., Jackson, A., Ingabire, R., Ouattara, G., Park, H., Gumbe, A., Chinyenze, K., Welsh, S., Verlinde, C., Clark, L., Chetty, P., Booley, M., Bizimana, J., Farah, B., Hayes, P., Zachariah, D., Syvertsen, K., Lim, M.F., Dally, L., Barin, B., Inoue, M., Hara, H., Hironaka, T., Shu, T., Hasegawa, M., Matano, T., Sayeed, E., Parks, C., Ackland, J., Fast, P.M., Gilmour, J., Cox, J.H., Lombardo, A., and Laufer, D. Clinical safety and immunogenicity of two HIV vaccines SeV-G (NP) and Ad35-GRIN in HIVuninfected, healthy adult volunteers. AIDS Res. Hum. Retroviruses 30 Suppl. 1:A85, Oct. 2014.

Terahara, K., Ishii, H., Nomura, T., Takahashi, N., Takeda, A., Shiino, T., Tsunetsugu-Yokota, Y., and Matano, T. Vaccine-induced CD107a+ CD4+ T cells are resistant to depletion following AIDS virus infection. J. Virol. 88:14232-14240, 2014.

Nomura, T., Yamamoto, H., Takahashi, N., Naruse, T.K., Kimura, A., and Matano, T. Identification of SIV Nef CD8+ T cell epitopes restricted by a MHC class I haplotype associated with lower viral loads in a macaque AIDS model. Biochem. Biophys. Res. Commun. 450:942-947, 2014.

Takebe, Y., Naito, Y., Raghwani, J., Fearnhill, E., Sano, T., Kusagawa, S., Mbisa, J., Zhang, H., Matano, T., Brown, A.L., Pybus, O., Dunn, D., and Kondo, M. Inter-continental dispersal of HIV-1 subtype B associated with transmission among men who have sex with men in Japan. J. Virol. 88:9864-9876, 2014.

Naruse, T.K., Akari, H., Matano, T., and Kimura, A. Divergence and diversity of ULBP2 genes in rhesus and cynomolgus macaques. Immunogenetics 66:161-170, 2014. 

Burwitz, B.J., Wu, H.L., Reed, J.S., Hammond, K.B., Newman, L.P., Bimber, B.N., Nimiyongskul, F.A., Leon, E.J., Maness, N.J., Friedrich, T.C., Yokoyama, M., Sato, H., Matano, T., O’Connor, D.H., and Sacha, J.B. Tertiary mutations stabilize CD8+ T lymphocyte escape-associated compensatory mutations following transmission of simian immunodeficiency virus. J. Virol. 88:3598-3604, 2014.

Iwamoto, N., Takahashi, N., Seki, S., Nomura, T., Yamamoto, H., Inoue, M., Shu, T., Naruse, T.K., Kimura, A., and Matano, T. Control of SIV replication by vaccine-induced Gag- and Vif-specific CD8+ T cells. J. Virol. 88:425-433, 2014.

Seki, S., and Matano, T. Development of vaccines using SeV vectors against AIDS and other infectious diseases. Sendai Virus Vector (Ed.: Nagai, Y.), Springer, 127-149, 2013.

Nishizawa, M., Hattori, J., Shiino, T., Matano, T., Heneine, W., Johnson, J.A., and Sugiura, W. Highly-sensitive allele-specific PCR testing identifies a greater prevalence of transmitted HIV drug resistance in Japan. PLoS ONE 8:e83150, 2013.

Nakane, T., Nomura, T., Shi, S., Nakamura, M., Naruse, T.K., Kimura, A., Matano, T.*, and Yamamoto, H.* Limited impact of passive non-neutralizing antibody immunization in acute SIV infection on viremia control in rhesus macaques. PLoS ONE 8:e73453, 2013

Shi, S., Seki, S., Matano, T., and Yamamoto, H. IL-21-producer CD4+ T cell kinetics during primary simian immunodeficiency virus infection. Microbes Infect. 15:697-707,2013.

Saito, A., Nomaguchi, M., Kono, K., Iwatani, Y., Yokoyama, M., Yasutomi, Y., Sato, H., Shioda, T., Sugiura, W., Matano, T., Adachi, A., Nakayama, E.E., and Akari, H. TRIM5 genotypes in cynomolgus monkeys primarily influence inter-individual diversity in susceptibility to monkey-tropic human immunodeficiency virus type 1. J. Gen. Virol. 94:1318-1324, 2013.

Kondo, M., Lemey, P., Sano, T., Itoda, I., Yoshimura, Y., Sagara, H., Tachikawa, N., Yamanaka, K., Iwamuro, S., Matano, T., Imai, M., Kato, S., and Takebe, Y. Emergence in Japan of an HIV-1 variant associated with MSM transmission in China: First indication for the international dissemination of the Chinese MSM lineage. J. Virol. 87:5351-5361, 2013.

Takahashi, N., Nomura, T., Takahara, Y., Yamamoto, H., Shiino, T., Takeda, A., Inoue, M., Iida, A., Hara, H., Shu, T., Hasegawa, M., Sakawaki, H., Miura, T., Igarashi, T., Koyanagi, Y., Naruse, T.K., Kimura, A., and Matano, T. A novel protective MHC-I haplotype not associated with dominant Gag-specific CD8+ T-cell responses in SIVmac239 infection of Burmese rhesus macaques. PLoS ONE 8:e54300, 2013.

Nomaguchi, M., Yokoyama, M., Kono, K., Nakayama, E.E., Shioda, T., Saito, A., Akari, H., Yasutomi, Y., Matano, T., Sato, H., and Adachi, A. Gag-CA Q110D mutation elicits TRIM5-independent enhancement of HIV-1mt replication in macaque cells. Microbes Infect. 15:56-65, 2013.

Kurihara, K., Takahara, Y., Nomura, T., Ishii, H., Iwamoto, N., Takahashi, N., Inoue, M., Iida, A., Hara, H., Shu, T., Hasegawa, M., Moriya, C., and Matano, T. Immunogenicity of repeated Sendai viral vector vaccination in macaques. Microbes Infect. 14:1169-1176, 2012.

Nomura, T. and Matano, T. Association of MHC-I genotypes with disease progression in HIV/SIV infections. Front. Microbiol. 3:234, 2012.

Ohtani, H., Naruse, T.K., Iwasaki, Y., Akari, H., Ishida, T., Matano, T., and Kimura, A. Lineage-specific evolution of T-cell immunoglobulin and mucin domain 1 gene in the primates. Immunogenetics 64:669-678, 2012.

Nomura, T., Yamamoto, H., Shiino, T., Takahashi, N., Nakane, T., Iwamoto, N., Ishii, H., Tsukamoto, T., Kawada, M., Matsuoka, S., Takeda, A., Terahara, K., Tsunetsugu-Yokota, Y., Iwata-Yoshikawa, N., Hasegawa, H., Sata, T., Naruse, T.K., Kimura, A., and Matano, T. Association of major histocompatibility complex class I haplotypes with disease progression after simian immunodeficiency virus challenge in Burmese rhesus macaques. J. Virol. 86:6481-6490, 2012.

Tee, K.K., Kamarulzaman, A., Matano, T., and Takebe, Y. Phylodynamic inference of infectious diseases caused by the human immunodeficiency virus, enterovirus 71, and the 2009 swine-origin human influenza virus. Future Virol. 7:1-10, 2012.

Takeuchi, H., Ishii, H., Kuwano, T., Inagaki, N., Akari, H., and Matano, T. Host cell species-specific effect of cyclosporine A on simian immunodeficiency virus replication. Retrovirology 9:3, 2012.

Seki, S., and Matano, T. CTL escape and viral fitness in HIV/SIV infection. Front. Microbiol. 2:267, 2012.

Ishii, H., Kawada, M., Tsukamoto, T., Yamamoto, H., Matsuoka, S., Shiino, T., Takeda, A., Inoue, M., Iida, A., Hara, H., Shu, T., Hasegawa, M., Naruse, T.K., Kimura, A., Takiguchi, M., and Matano, T. Impact of vaccination on cytotoxic T lymphocyte immunodominance and cooperation against simian immunodeficiency virus replication in rhesus macaques. J. Virol. 86:738-745, 2012.

Saito, Y., Naruse, T.K., Akari, H., Matano, T., and Kimura, A. Diversity of MHC class I haplotypes in cynomolgus macaques. Immunogenetics 64:131-141, 2012.

Moriya, C., Horiba, S., Kurihara, K., Kamada, T., Takahara, Y., Inoue, M., Iida, A., Hara, H., Shu, T., Hasegawa, M., and Matano, T. Intranasal Sendai viral vector vaccination is more immunogenic than intramuscular under pre-existing anti-vector antibodies. Vaccine 29:8557-8563, 2011.

Nakamura, M., Takahara, Y., Ishii, H., Sakawaki, H., Horiike, M., Miura, T., Igarashi, T., Naruse, T.K., Kimura, A., Matano, T., and Matsuoka, S. Major histocompatibility complex class I-restricted cytotoxic T lymphocyte responses during primary simian immunodeficiency virus infection in Burmese rhesus macaques. Microbiol. Immunol. 55:768-773, 2011.

Matsuoka, S., and Matano, T. Strategy for prevention of HIV-1 transmission. Journal of Disaster Research 6:421-425, 2011.

Naruse, T.K., Okuda, Y., Mori, K., Akari, H., Matano, T., and Kimura, A. ULBP4/RAET1E is highly polymorphic in the Old World monkey. Immunogenetics 63:501-509, 2011.

Takahara, Y., Matsuoka, S., Kuwano, T., Tsukamoto, T., Yamamoto, H., Ishii, H., Nakasone, T., Takeda, A., Inoue, M., Iida, A., Hara, H., Shu, T., Hasegawa, M., Sakawaki, H., Horiike, M., Miura, T., Igarashi, T., Naruse, T.K., Kimura, A., and Matano, T. Dominant induction of vaccine antigen-specific cytotoxic T lymphocyte responses after simian immunodeficiency virus challenge. Biochem. Biophys. Res. Commun. 408:615-619, 2011.

Saito, A., Nomaguchi, M., Iijima, S., Kuroishi, A., Yoshida, T., Lee, Y.-J., Hayakawa, T., Kono, K., Nakayama, E.E., Shioda, T., Yasutomi, Y., Adachi, A., Matano, T., and Akari, H. Improved capacity of a monkey-tropic HIV-1 derivative to replicate in cynomolgus monkeys with minimal modifications. Microbes Infect., 13:58-64, 2011.


英語論文(2006~2010年)   ペー ジトップへ戻る

Inagaki, N., Takeuchi, H., Yokoyama, M., Sato, H., Ryo, A., Yamamoto, H., Kawada, M., and Matano, T. A structural constraint for functional interaction between N-terminal and C-terminal domains in simian immunodeficiency virus capsid proteins. Retrovirology 7:90, 2010.

Iwamoto, N., Tsukamoto, T., Kawada, M., Takeda, A., Yamamoto, H., Takeuchi, H., and Matano, T. Broadening of CD8+ cell responses in vaccine-based simian immunodeficiency virus controllers. AIDS, 24:2777-2787, 2010.

Naruse, T.K., Chen, Z., Yanagida, R., Yamashita, T., Saito, Y., Mori, K., Akari, H., Yasutomi, Y., Miyazawa, M., Matano, T., and Kimura, A. Diversity of MHC class I genes in Burmese-origin rhesus macaques. Immunogenetics, 62:601-611, 2010.

Yamamoto, H., and Matano, T. Neutralizing antibodies in SIV control: co-impact with T cells. Vaccine 28S:B13-B17, 2010.

Yu, S., Feng, X., Shu, T., Matano, T., Hasegawa, M., Wang, X., Li, H., Li, Z., Zhong, R., and Zeng, Y. Comparison of the expression and immunogenicity of wild-type and sequence-modified HIV-1 gag genes in a recombinant Sendai virus vector. Curr. HIV Res., 8:199-206, 2010.

Tsukamoto, T., Takeda, A., Yamamoto, T., Yamamoto, H., Kawada, M., and Tetsuro Matano, T. Impact of cytotoxic-T-lymphocyte memory induction without virus-specific CD4+ T-cell help on control of a simian immunodeficiency virus challenge in rhesus macaques. J. Virol. 83:9339-9346, 2009.

Yamamoto, T.#, Iwamoto, N.#, Yamamoto, H.#, Tsukamoto, T., Kuwano, T., Takeda, A., Kawada, M., Tsunetsugu-Yokota, Y., and Matano, T. Polyfunctional CD4+ T-cell induction in neutralizing antibody-triggered control of simian immunodeficiency virus infection. J. Virol. 83:5514-5524, 2009.

Takeda, A., Igarashi, H., Kawada, M., Tsukamoto, T., Yamamoto, H., Inoue, M., Iida, A., Shu, T., Hasegawa, M., and Matano, T. Evaluation of the immunogenicity of replication-competent V-knocked-out and replication-defective F-deleted Sendai virus vector-based vaccines in macaques. Vaccine 26:6839-6843, 2008.

Yu, S., Feng, X., Shu, T., Matano, T., Hasegawa, M., Wang, X., Ma, H., Li, H., Li, Z., and Zeng, Y. Potent specific immune responses induced by prime-boost-boost strategies based on DNA, adenovirus, and Sendai virus vectors expressing gag gene of Chinese HIV-1 subtype B. Vaccine 26:6124-6131, 2008.

Kawada, M., Tsukamoto, T., Yamamoto, H., Iwamoto, N., Kurihara, K., Takeda, A., Moriya, C., Takeuchi, H., Akari, H., and Matano, T. Gag-specific cytotoxic T lymphocyte-based control of primary simian immunodeficiency virus replication in a vaccine trial. J. Virol. 82:10199-10206, 2008.

Feng, X., Yu, S., Shu, T., Matano, T., Hasegawa, M., Wang, X., Ma, H., Li, H., and Zeng, Y. Immunogenicity of DNA and recombinant Sendai virus vaccines expressing the HIV-1 gag gene. Virologica Sinica, 23:295-304, 2008.

Yamamoto, H., and Matano, T. Anti-HIV adaptive immunity: determinants for viral persistence. Rev. Med. Virol. 18:293-303, 2008.

Takeuchi, H., and Matano, T. Host factors involved in resistance to retroviral infection. Microbiol. Immunol. 52:318-325, 2008.

Moriya, C., Horiba, S., Inoue, M., Iida, A., Hara, H., Shu, T., Hasegawa, M., and Matano, T. Antigen-specific T-cell induction by vaccination with a recombinant Sendai virus vector even in the presence of vector-specific neutralizing antibodies in rhesus macaques. Biochem. Biophys. Res. Commun. 371:850-854, 2008.

Tsukamoto, T., Dohki, S., Ueno, T., Kawada, M., Takeda, A., Yasunami, M., Naruse, T., Kimura, A., Takiguchi, M., and Matano, T. Determination of a major histocompatibility complex class I restricting simian immunodeficiency virus Gag241-249 epitope. AIDS 22:993-994, 2008.

Seki, S., Kawada, M., Takeda, A., Igarashi, H., Sata, T., and Matano, T. Transmission of simian immunodeficiency virus carrying multiple cytotoxic-T-lymphocyte escape mutations with diminished replicative ability can result in AIDS progression in rhesus macaques. J. Virol. 82:5093-5098, 2008.

Moriya, C., Igarashi, H., Takeda, A., Tsukamoto, T., Kawada, M., Yamamoto, H., Inoue, M., Iida, A., Shu, T., Hasegawa, M., Nagai, Y., and Matano, T. Abrogation of AIDS vaccine-induced cytotoxic T lymphocyte efficacy in vivo due to a change in viral epitope flanking sequences. Microbes Infect., 10:285-292, 2008.

Takeda, A., and Matano, T. Inhibition of infectious murine leukemia virus production by Fv-4 env gene products exerting dominant negative effect on viral envelope glycoprotein. Microbes Infect., 9:1590-1596, 2007.

Tsukamoto, T., Yuasa, M., Yamamoto, H., Kawada, M., Takeda, A., Igarashi, H., and Matano, T. Induction of CD8+ cells able to suppress CCR5-tropic simian immunodeficiency virus SIVmac239 replication by controlled infection of CXCR4-tropic simian-human immunodeficiency virus in vaccinated rhesus macaques. J. Virol. 81:11640-11649, 2007.

Morikawa, Y., Goto, T., Yasuoka, D., Momose, F., and Matano, T. Defect of human immunodeficiency virus type 2 Gag assembly in saccharomyces cerevisiae. J. Virol. 81:9911-9921, 2007.

Yamamoto, H., Kawada, M., Takeda, A., Igarashi, H., and Matano, T. Post-infection immunodeficiency virus control by neutralizing antibodies. PLoS ONE 2:e540, 2007.

Nagai, Y., Inoue, M., Iida, A., Zhu, Y.-F., Hasegawa, M., Kato, A., and Matano, T. Sendai virus engineering: From reverse genetics to vector development. Virus Expression Vectors (Ed.: Hefferon, K.L.), Trasworld Research Network, 123-146, 2007.

Kawada, M., Tsukamoto, T., Yamamoto, H., Takeda, A., Igarashi, H., Watkins, D.I., and Matano, T. Long-term control of simian immunodeficiency virus replication with central memory CD4+ T-cell preservation after non-sterile protection by a cytotoxic T lymphocyte-based vaccine. J. Virol. 81:5202-5211, 2007.

Takahashi-Tanaka, Y., Yasunami, M., Naruse, T., Hinohara, K., Matano, T., Mori, K., Miysazawa, M., Honda, M., Yasutomi, Y., Nagai, Y., and Kimura, A. Reference strand-mediated conformation analysis (RSCA)-based typing of multiple alleles in the rhesus macaque MHC class I Mamu-A and Mamu-B loci. Electrophoresis 28:918-924, 2007.

Yamamoto, H., Kawada, M., Tsukamoto, T., Takeda, A., Igarashi, H., Miyazawa, M., Naruse, T., Yasunami, M., Kimura, A., and Matano, T. Vaccine-based long-term stable control of simian-human immunodeficiency virus 89.6PD replication in rhesus macaques. J. Gen. Virol. 88:652-659, 2007.

Kawada, M., Igarashi, H., Takeda, A., Tsukamoto, T., Yamamoto, H., Dohki, S., Takiguchi, M., and Matano, T. Involvement of multiple epitope-specific cytotoxic T-lymphocyte responses in vaccine-based control of simian immunodeficiency virus replication in rhesus macaques. J. Virol. 80:1949-1958, 2006.


英語論文(2001~2005年)   ペー ジトップへ戻る

Kobayashi, M., Igarashi, H., Takeda, A., Kato, M., and Matano, T. Reversion in vivo after inoculation of a molecular proviral DNA clone of simian immunodeficiency virus with a cytotoxic-T-lymphocyte escape mutation. J. Virol. 79:11529-11532, 2005.

Mori, K., Sugimoto, C., Ohgimoto, S., Shioda, T., Kusagawa, S., Takebe, Y., Kano, M., Matano, T., Yuasa, T., Kitaguchi, D., Miyazawa, M., Takahashi, Y., Yasunami, M., Kimura, A., Yamamoto, N., Suzuki, Y., and Nagai, Y. Influence of glycosylation on the efficacy of an Env-based vaccine against SIVmac239 in a macaque AIDS model. J. Virol. 79:10386-10396, 2005.

Kato, M., Igarashi, H., Takeda, A., Sasaki, Y., Nakamura, H., Kano, M., Sata, T., Iida, A., Hasegawa, M., Horie, S., Higashihara, E., Nagai, Y., and Matano, T. Induction of Gag-specific T-cell responses by therapeutic immunization with a Gag-expressing Sendai virus vector in macaques chronically infected with simian-human immunodeficiency virus. Vaccine 23:3166-3173, 2005.

Kato, M., Igarashi, H., Takeda, A., Horie, S., Higashihara, E., and Matano, T. Stimulation of virus-specific T cell responses by dendritic cell vaccination in the chronic phase of simian AIDS models. Jpn. J. Infect. Dis. 57:220-223, 2004.

Matano, T., Kobayashi, M., Igarashi, H., Takeda, A., Nakamura, H., Kano, M., Sugimoto, C., Mori, K., Iida, A., Hirata, T., Hasegawa, M., Yuasa, T., Miyazawa, M., Takahashi, Y., Yasunami, M., Kimura, A., O'Connor, D.H., Watkins, D.I., and Nagai, Y. Cytotoxic T lymphocyte-based control of simian immunodeficiency virus replication in a preclinical AIDS vaccine trial. J. Exp. Med. 199:1709-1718, 2004.

Lun, W.-H., Takeda, A., Nakamura, H., Kano, M., Mori, K., Sata, T., Nagai, Y., and Matano, T. Loss of virus-specific CD4+ T cells with increases in viral loads in the chronic phase after vaccine-based partial control of primary simian immunodeficiency virus replication in macaques. J. Gen. Virol. 85:1955-1963, 2004.

Takeda, A., Nakamura, H., and Matano, T. Evaluation of simian immunodeficiency virus-specific immune responses induced by a defective proviral DNA vaccine in macaques. Jpn. J. Infect. Dis. 56:172-173, 2003.

Takeda, A., Igarashi, H., Nakamura, H., Kano, M., Iida, A., Hirata, T., Hasegawa, M., Nagai, Y., and Matano, T. Protective efficacy of an AIDS vaccine, a single DNA-prime followed by a single booster with a recombinant replication-defective Sendai virus vector, in a macaque AIDS model. J. Virol. 77:9710-9715, 2003.

Matano, T., Kano, M., Takeda, A., Nakamura, H., Nomura, N., Furuta, Y., Shioda, T., and Nagai, Y. No significant enhancement of protection by Tat-expressing Sendai viral vector-booster in a macaque AIDS model. AIDS 17:1392-1394, 2003.

Matano, T. Recent advances in AIDS vaccine preclinical trials: challenges against the chronic disease. Current Topics in Virology 2:179-185, 2002.

Kano, M., Matano, T., Kato, A., Shioda, T., and Nagai, Y. Induction of HIV-1-specific neutralizing antibodies in mice vaccinated with a recombinant Sendai virus vector. Jpn. J. Infect. Dis. 55:59-60, 2002.

Kano, M., Matano, T., Kato, A., Nakamura, H., Takeda, A., Suzaki, Y., Ami, Y., Terao, K., and Nagai, Y. Primary replication of a recombinant Sendai viral vector in macaques. J. Gen. Virol. 83:1377-1386, 2002.

Matano, T., Kano, M., Nakamura, H., Takeda, A., and Nagai, Y. Rapid appearance of secondary immune responses and protection from acute CD4 depletion after a highly pathogenic immunodeficiency virus challenge in macaques vaccinated with a DNA-prime/Sendai viral vector-boost regimen. J. Virol. 75:11891-11896, 2001.

Nakamura, H., Takeda, A., and Matano, T. Postbinding fusion function contributed by a chimeric murine leukemia virus envelope protein. Arch. Virol. 146:953-961, 2001.

Matano, T. The optimal molar ratio between a binding-deficient and a fusion-deficient murine leukemia virus envelope proteins for complementation to induce syncytia. Jpn. J. Infect. Dis. 54:32-34, 2001.


英語論文(2000年以前)   ペー ジトップへ戻る

Matano, T., Kano, M., Odawara, T., Nakamura, H., Takeda, A., Mori, K., Sata, T., and Nagai, Y. Induction of protective immunity against pathogenic simian immunodeficiency virus by a foreign receptor-dependent replication of an engineered avirulent virus. Vaccine 18:3310-3318, 2000.

Takeda, A., Nakamura, H., and Matano, T. Confined replication of a chimeric simian immunodeficiency virus. Jpn. J. Infect. Dis. 53:209-211, 2000.

Kano, M., Matano, T., Nakamura, H., Takeda, A., Kato, A., Ariyoshi, K., Mori, K., Sata, T., and Nagai, Y. Elicitation of protective immunity against simian immunodeficiency virus infection by a recombinant Sendai virus expressing the Gag protein. AIDS 14:1281-1282, 2000.

Igarashi, T., Endo, Y., Englund, G., Sadjadpour, R., Matano, T., Buckler, C., Buckler-White, A., Plishka, R., Theodore, T., Shibata, R., and Martin, M.A. Emergence of a highly pathogenic simian/human immunodeficiency virus in a rhesus macaque treated with anti-CD8 mAb during a primary infection with a nonpathogenic virus. Proc. Natl. Acad. Sci. USA 96:14049-14054, 1999.

Matano, T. Retrovirus and autoimmune diseases. Jpn. J. Infect. Dis. 52:106-109, 1999.

Matano, T. Inhibition of infectious HIV-1 production by an intracellular chimeric CD4. Journal of AIDS Research 1:79-83, 1999.

Matano, T., Shibata, R., Siemon, C., Connors, M., Lane, H.C., and Martin, M.A. Administration of an anti-CD8 monoclonal antibody interferes with the clearance of SIV/HIV chimeric virus during primary infections of rhesus macaques. J. Virol. 72:164-169, 1998.

Shibata, R., Maldarelli, F., Siemon, C., Matano, T., Parta, M., Miller, G., Fredrickson, T., and Martin, M.A. Infection and pathogenicity of chimeric simian-human immunodeficiency viruses in macaques: determinants of high virus loads and CD4 killing. J. Infect. Dis. 176:362-373, 1997.

Shibata, R., Siemon, C., Rizvi, T.A., Matano, T., Satterfield, W.C., Lane, H.C., and Martin, M.A. Reactivation of HIV type 1 in chronically infected chimpanzees following xenostimulation with human cells or with pulses of corticosteroid. AIDS Res. Hum. Retroviruses 13:377-381, 1997.

Ohshima, M., Odawara, T., Matano, T., Sakahira, H., Kuchino, Y., Iwamoto, A., and Yoshikura, H. Possible role of splice acceptor site in expression of unspliced gag-containing message of Moloney murine leukemia virus. J. Virol. 70:2286-2295, 1996.

Matano, T., Odawara, T., Iwamoto, A., and Yoshikura, H. Targeted infection of a retrovirus bearing a CD4-Env chimera into human cells expressing human immunodeficiency virus type 1. J. Gen. Virol. 76:3165-3169, 1995.

Matano, T., Odawara, T., Ohshima, M., Iwamoto, A., and Yoshikura, H. Interaction between the dominant negative mutant and the wild-type envelope proteins of Friend murine leukemia virus. J. Virol. 68:6079-6082, 1994.

Matano, T. Antiviral strategy based on intracellular immunity. Japanese Journal of Medical Science and Biology (Jpn. J. Infect. Dis.) 47:123-124, 1994.

Matano, T., Tamai, K., and Kurokawa, T. Adaptation of the skeletal muscle in limb lengthening. A light diffraction study on the sarcomere length in situ. J. Orthop. Res. 12:193-196, 1994.

Matano, T., Odawara, T., Ohshima, M., Yoshikura, H., and Iwamoto, A. trans-Dominant interference with virus infection at two different stages by a mutant envelope protein of Friend murine leukemia virus. J. Virol. 67:2026-2033, 1993.


和文論文 (2021年以降)    ペー ジトップへ戻る

俣野哲朗.COVID-19の感染免疫学.カレントテラピー [特集:COVID-19ーその診断と治療](ライフメディコム) 39(11):1087-1092, 2021.

Alitzel Anzurez、立川(川名)愛、俣野哲朗.HIV感染症と免疫老化.日本臨床【特集:新興・再興感染症update】(日本臨床社) 79(2):188-194, 2021.

和 文論文(2016~2020年)   ペー ジトップへ戻る

菅野芳明、俣野哲朗.HIVワクチンの開発と可能性.呼吸器内科、特集ー呼吸器内科に必要な感染症の知識:HIV編(科学評論 社)36:473-477, 2019.

石井洋、俣野哲朗.エイズワクチンの開発戦略と開発の現況:国立感染症研究所俣野研究室.HIV感染症と AIDSの治療(メディカルレビュー社)9:58-61, 2018.

俣野哲朗.エイズワクチン.ワクチンー基礎から臨床まで.日本ワクチン学会(朝倉書店)274-279, 2018.

俣野哲朗.遺伝子組換え実験.ウイルス検査法ー臨床と検査室のための手引き.日本臨床ウイルス学会(株式会社春恒 社)377-382, 2018.

俣野哲朗.グローバルHIVコントロールに向けたワクチン開発.医学のあゆみ:近未来のワクチンー開発研究 の潮流と課題(医歯薬出版 株式会社)264(5):464-468, 2018.

中村碧、俣野哲朗.エイズワクチン開発の近況.臨床と研究(大道学館出版部)93:1183-1186, 2016.

野村拓志、俣野哲朗.HIV粘膜感染と宿主免疫.実験医学(羊土社)34:2162-2166, 2016.

俣野哲朗.注目される最近の話題:抗HIV免疫増強によるHIV感染症の予防と治療.化学療法の領域(医薬ジャーナル 社)32(5):1039-1045, 2016.



和文論文(2011~2015年)  ペー ジトップへ戻る


伊勢田すみれ、俣野哲朗.HIV感染症の予防と治癒に向けて.実験医学(羊 土社) 33:2727-2731, 2015.

竹村太地郎、俣野哲朗.次世代シークエンスを利用したHIV研究の新展開.臨床とウイルス(日本臨床ウイル ス学会) 43:131-136, 2015.

俣野哲朗.HIV感染症制圧に向けて.医学のあゆみ:感染症最前線とグローバル・ヘルス(医歯薬出版株式会 社)253(1):99-104, 2015.

俣野哲朗.HIV/AIDSの現状とワクチンの未来.性の健康(性の健康医学財団)13:20-22, 2015.

俣野哲朗.不活化全粒子経鼻インフルエンザワクチンの臨床応用に向けた研究.臨床評価(臨床評価刊行会)42 Suppl XXXIII:71-73, 2014.

俣野哲朗.ウイルス感染に対するワクチン.病原微生物学ー基礎と臨床ー(荒川宣親・神谷茂・柳雄介編、東京化学同 人)225-229, 2014.

石井洋、俣野哲朗.センダイウイルス.遺伝子治療・診断の最先端技術と新しい医薬品・診断薬の開発(技術情 報協会)236-241, 2014.

五領舞衣、俣野哲朗.グローバル感染症:エイズワクチン.特集:次世代感染症ワクチン.最新医学(最新医学 社)69(4):804-809, 2014.

俣野哲朗.エイズワクチン開発の現状と今後の展望.ヒューマンサイエン ス(ヒューマンサイエンス振興財団)25(1):28-31, 2014.

俣野哲朗.エイズワクチン開発について. ワクチン開発における最新動向(情報機構)151-163, 2013.

俣野哲朗.エイズワクチン開発研究の最前線.性の健康(性の健康医学財団) No.1:6-7, 2013.

吉村和久、俣野哲朗.HIVエンベロープの中和抗体抵抗性を解除する鍵.化学療法の領域(医薬ジャーナル 社)29(8):1739-1745, 2013.

史蕭逸、俣野哲朗.ワクチン開発の現状.血液フロンティア【特集:HIV感染症2013ー現状と展望ー】(医薬ジャーナル 社)23(6):767-772, 2013.

俣野哲朗.ウイルス感染に対する反応.標準免疫学(谷口克監修、宮坂昌之・小安重夫編集、医学書院) 第3版第II編第9章B、p.280-288, 2013.

俣野哲朗.国立感染症研究所エイズ研究センターの取り組み.Confronting HIV 2012(マッキャン・ヘルスケア) No.42:13, 2012.

俣野哲朗.ワクチン開発の理論.新編ウイルスの今日的意味(柳雄介・堤裕幸編集、医薬ジャーナル社)p.109-116, 2012.

中村碧、俣野哲朗.HIVに対する治療ワクチン.日本臨床【特集:抗ウイルス薬】(日本臨床社) 70(4):676-680, 2012.

栗原京子、俣野哲朗.HIVワクチンー近年の臨床試験から.綜合臨床【特集:Vaccine preventable diseasesを制御するためのわが国の課題】(永井書店) 60:2204-2206, 2011.

石井洋、俣野哲朗.予防エイズワクチン開発の現状.日本臨床【特集:ワクチン】(日本臨床社) 69(9):1622-1627, 2011.

俣野哲朗.ワクチン開発の理論.連載:ウイルスの今日的意味17、基礎ウイルス学の観点から(9).化学療法の領域.医薬 ジャー ナル社.27(7):1575-1582, 2011.

俣野哲朗.Cutting Edge:エイズワクチン開発.Medical Science Digest(ニューサイエンス社)37(5):171-172, 2011.

高原悠佑、俣野哲朗.HIV-1感染症とワクチン開発.Pharma Medica(メディカルレビュー社)29(4):37-41, 2011.


和文論文(2006~2010年)  ペー ジトップへ戻る

塚本徹雄、俣野哲朗.AIDS.臨床粘膜免疫学(清野宏編集、シナジー)p.455-464, 2010.

俣野哲朗.HIV/AIDS予防研究の現状ーワクチン開発を中心に.公衆衛生(医学書院) 74:936-940, 2010.

松岡佐織、俣野哲朗.HIV.臨床検査(医学書院)54:1407-1412, 2010.

中根拓、俣野哲朗.エイズワクチン開発の問題点.次世代ワクチンの産業技術応用(神谷齊監修、シーエムシー出 版)p.145-152, 2010.

松下修三、横山勝、宮内浩典、松田善衛、俣野哲朗、岩谷靖雅.HIV細胞侵入とその防御機序.日本エイズ学会誌 12: 67-73, 2010.

石井洋、俣野哲朗.エイズ動物モデル.日本臨床 [特集:HIV/AIDS] (日本臨床社) 68:423-427, 2010.

高橋尚史、俣野哲朗.エイズワクチン開発の現状と問題点.DDS(日本医学館) 25:46-51, 2010.

野村拓志、俣野哲朗.エイズワクチン開発の論理.ウイルス(日本ウイルス学会) 59:267-276, 2009.

俣野哲朗.エイズワクチン開発研究の展望.日本内科学会雑誌(日本内科学会) 98:2827-2834, 2009.

俣野哲朗.エイズワクチン開発研究の新展開(生涯教育講座:自然免疫とワクチン).大阪大学医学部学友会会誌.医学振興銀杏 会.29:41-44, 2009.

足立昭夫、俣野哲朗、中山英美、野間口雅子、五十嵐樹彦、上野貴将.ヒトはなぜエイズになるのか.日本エイズ学会誌 11:92-99, 2009.

岩本南、俣野哲朗.HIVワクチン開発の現状と今後の展望.Bio Clinica(北隆館) 24:630-634, 2009.

塚本徹雄、俣野哲朗.T細胞免疫系は己をまもれるか? HIV は問う.実験医学(増刊)(羊土社) 27:1634-1638, 2009.

武内寛明、俣野哲朗.エイズウイルスの増殖機構の解析とその制御法の開発.蛋白質核酸酵素(増刊)(共立出版) 54:947-952, 2009.

桑野哲矢、俣野哲朗.抗HIV免疫療法と治療ワクチン開発の展望.化学療法の領域(医薬ジャーナル社) 25:305-309, 2009.

俣野哲朗.ノーベル医学生理学賞:ヒト慢性感染症の起因ウイルス発見.実験医学(羊土社) 26:3040-3041, 2008.

稲垣奈都子、俣野哲朗.HIV感染機構とワクチン開発研究.実験医学(羊土社) 26:2897-2901, 2008.

関紗由里、俣野哲朗.HIVワクチン.日本臨床 [特集:ワクチン] (日本臨床社) 66:1965-1969, 2008.

俣野哲朗.センダイウイルスベクターAIDSワクチン.Confronting HIV 2008(マッキャン・ヘルスケア) No.34:8-9, 2008.

宮澤正顯、横田(恒次)恭子、三浦聡之、滝口雅文、俣野哲朗.HIVに対する宿主防御免疫機構:自然免疫から適応免疫まで. 日本 エイズ学会誌 10:85-87, 2008.

川田真幹、俣野哲朗.HIVワクチン.Virus Report(医療ジャーナル社) 5:32-39, 2008.

武内寛明、俣野哲朗.動物AIDSモデルの研究はどこまで進んだか.治療学(ライフサイエンス出版) 42:557-563, 2008.

山本浩之、俣野哲朗.HIV-1ワクチン開発への感染免疫学.ウイルス(日本ウイルス学会) 57:133-140, 2007.

守屋智草、俣野哲朗.HIV粘膜感染と感染防御免疫.実験医学(増刊)(羊土社) 25:3362-3365, 2007.

守屋智草、俣野哲朗.免疫不全ウイルスワクチンの開発.治療学(ライフサイエンス出版) 41:1059-1062, 2007.

俣野哲朗.エイズワクチンの集団予防効果.Virus Report(医療ジャーナル社) 4:9-10, 2007.

川田真幹、俣野哲朗.HIV感染に対する宿主適応免疫 [ワクチン開発への論理的基盤].蛋白質核酸酵素(増刊)(共立出版) 52:1227-1230, 2007.

俣野哲朗、楠和久.エイズワクチン開発の展望.診断と治療(診断と治療社) 94:2292-2296, 2006.


和文論文(2001~2005年)  ペー ジトップへ戻る

高橋秀実、滝口雅文、田中勇悦、俣野哲朗、染谷健二、本多三男.HIV/AIDSの病態進行とワクチン開発の進歩.日本エイ ズ学 会誌 7:83-92, 2005.

塚本徹雄、俣野哲朗.「可能性」から「条件付き確からしさ」へ:感染免疫の理解に基いたエイズワクチン開発.化学療法の領域 (医 療ジャーナル社) 21:1141-1145, 2005.

俣野哲朗、松頭省.HIVワクチン開発の現状.Bio Clinica(北隆館) 20:718-723, 2005.

俣野哲朗.HIVワクチン.臨床免疫学(別冊[下] 基礎研究の進歩と最新の臨床)(日本臨床) 63(suppl.5):659-665, 2005.

俣野哲朗.エイズワクチン開発の現状.臨床とウイルス(日本臨床ウイルス学会) 32:355-361, 2004.

滝口雅文、上野貴将、俣野哲朗、松尾和浩、本多三男.エイズ免疫と日本におけるワクチン研究の進展.日本エイズ学会誌 6:82-90, 2004.

山本浩之、俣野哲朗.HIVワクチン.細胞工学(秀潤社) 23:791-794, 2004.

川田真幹、俣野哲朗.HIVワクチン.総合臨床(永井書店) 53:1976-1980, 2004.

俣野哲朗.HIVワクチン研究の進歩と応用.現代医療(現代医療社) 35:1317-1322, 2003.

俣野哲朗.最新世界HIV/エイズ状況報告:ウイルスの変異の早さと多様性が開発の壁.Medical Asahi 31:20-21, 2002.

俣野哲朗.エイズワクチン.臨床と微生物(近代出版) 29:133-136, 2002.

俣野哲朗.AIDSワクチン.ヒトレトロウイルス研究の最前線(山本直樹編、シュプリンガー・フェアラーク東 京)p.87-94, 2002.

俣野哲朗.DNAワクチン.Medical Practice(文光堂) 18:1036-1037, 2001.

俣野哲朗.AIDSワクチンの動物モデル.治療学(ライフサイエンス出版) 35:224-227, 2001.


和文論文(2000年以前)  ペー ジトップへ戻る

俣野哲朗.GFP.バイオイメージングの最先端 (監修:石川春律、先端医療技術研究所)p.57-59, 1999.

俣野哲朗、永井美之.エイズワクチンをめぐる新しい動き.感染症(藤沢薬品工業) 29:225-231, 1999.

俣野哲朗、玉井和哉、黒沢尚.感染性ろう孔形成をみた下腿異所性骨化の2例.整形外科 40:1375-1378, 1989.