Challenges
■ Despite the growing body of knowledge on rational use interventions, numerous studies have documented the continuing widespread irrational prescribing of drugs.
■ injection therapy can also be an example of irrational drug use.
■ knowledge alone is not enough to change behaviour, and that complex and multifaceted solutions are needed.
■ Many new drugs and second-line drugs are very expensive and accordingly unaffordable for many governments and consumers.