• Prof. Mizushima has been recognized as Web of Science, Highly Cited Researchers in 2024 (11th consecutive year).

    Read More

News/Topics

and More

2025/02/19
Kobatake-san received the Excellent Poster Award at the 2024 ‘Medical Scientist Training Program’ Retreat
2025/02/06
Recruitment of graduate students
2024/11/20
Prof. Mizushima has been recognized as Web of Science, Highly Cited Researchers in 2024 (11th consecutive year).
2024/10/18
Dr. Hayashi won an Excellent Poster Award at the 16th Autophagy Research Meeting for Young Scientists
2024/07/19
Jing Zhang-san won the Best Student Poster Presentation Award at The 76th Annual Meeting of the Japanese Society for Cell Biology
2024/07/06
Cantona-san won the Best Poster Award at WINGS LST general meeting
2024/02/16
Yamaguchi-san received the Best Poster Abstract Award at the 2023 ‘Medical Scientist Training Program’ Retreat
2023/12/24
Kanda-san won the MBSJ2023 Best Science Pitch Award at the 46th Annual Meeting of the Molecular Biology Society of Japan
2023/12/01
Dr. Eguchi won the Best Presentation Award at the 15th Autophagy Research Meeting for Young Scientists
2023/11/20
Prof. Mizushima have been recognized as Web of Science, Highly Cited Researchers in 2023 (10th straight year).
2023/11/20
Kanda-san, Okawa-san and Nagashima-san won Young Scientists Presentation Award of Excellence at the 96rd Annual Meeting of Japanese Biochemical Society
2023/11/20
Dr. Eguchi won the EMBO reports poster prize at the EMBO COB Workshop on Membrane shaping and remodeling by proteins in Kunming
2023/06/23
Prof. Mizushima awarded inaugural Beth Levine, M.D. Prize in Autophagy Research
2023/06/19
Okawa-san won an Excellent Poster Award at the 22th BioUT (Life Science Symposium at the University of Tokyo)
2023/02/15
Nagashima-san and Suzuki-san received an Excellent Poster Abstract Award and the Best Poster Abstract Award respectively at the 2022 ‘Medical Scientist Training Program’ Retreat

Recent Publications (Original)

and More

2024/10/25
Autophagy adaptors mediate Parkin-dependent mitophagy by forming sheet-like liquid condensates (Yang et al. EMBO J)
2024/09/17
Organelle landscape analysis using a multi-parametric particle-based method (Kurikawa, Honda et al. PLoS Biol.)
2024/08/15
Optogenetic tools for inducing organelle membrane rupture (Nagashima et al. bioRxiv)
2024/06/05
Syntaxin 17 recruitment to mature autophagosomes is temporally regulated by PI4P accumulation (Shinoda et al. eLife)
2024/01/04
Experimental determination and mathematical modeling of standard shapes of forming autophagosomes (Sakai et al., Nat. Commun.)
2023/08/18
TAX1BP1 recruits ATG9 vesicles through SCAMP3 binding (Hama et al. bioRxiv)
2023/07/06
Comprehensive analysis of autophagic functions of WIPI family proteins and their implications for the pathogenesis of β-propeller associated neurodegeneration (Shimizu et al., Hum Mol Genet.)
2023/06/28
Unique amphipathic α helix drives membrane insertion and enzymatic activity of ATG3 (Nishimura et al., Sci Adv.)
2023/03/03
The pH-sensing Rim101 pathway regulates cell size in budding yeast
2022/12/22
Quantitative 3D correlative light and electron microscopy of organelle association during autophagy (Takahashi et al., Cell Struct Funct.)
2022/09/06
Ubiquitination of phosphatidylethanolamine in organellar membranes (Sakamaki et al., Mol. Cell)
2022/08/31
NCOA4 drives ferritin phase separation to facilitate macroferritinophagy and microferritinophagy(大島 et al., J. Cell Biol.)
2022/08/16
A pulse-chasable reporter processing assay for mammalian autophagic flux with HaloTag (Yim et al., eLife)
2022/04/20
Evolutionary diversification of the autophagy-related ubiquitin-like conjugation systems (Zhang et al., Autophagy)
2022/04/20
Phosphorylation by casein kinase 2 enhances the interaction between ER-phagy receptor TEX264 and ATG8 proteins (Chino et al., EMBO Rep.)

Recent Publications (Review)

and More

2025/01/29
Autophagic flux measurement: cargo degradation versus generation of degradation products (Mizushima, Curr Opin Cell Biol.)
2023/04/28
Ubiquitination of non-protein substrates (Sakamaki and Mizushima, Trends Cell Biol.)
2023/01/13
Autophagy genes in biology and disease (Yamamoto, Zhang et al., Nat Rev Genet.)
2022/05/25
Transient visit of STX17 (syntaxin 17) to autophagosomes (Koyama-Honda and Mizushima, Autophagy)
2022/02/03
Regulation of ER-derived membrane dynamics by the DedA domain-containing proteins VMP1 and TMEM41B (Hama, Morishita et al., EMBO Rep.)
2021/07/11
Breakthroughs and bottlenecks in autophagy research (Mizushima, et al., Trends Mol Med)
2021/07/01
The evolution of autophagy proteins – diversification in eukaryotes and potential ancestors in prokaryotes (Zhang, et al., J Cell Sci)
2020/10/15
Autophagy in human diseases (*Mizushima, N., Levine, B. , N. Engl. J. Med, 2020)
2020/08/22
Beth Levine 1960-2020 (Simon et al. Nat Cell Biol. 2020)
2020/08/21
Autophagy assays for biological discovery and therapeutic development (Mizushima et al. Trends Biochem Sci. 2020)
2020/03/02
ER-phagy: Quality control and turnover of endoplasmic reticulum (Chino et al., Trends Cell Biol)
2020/02/11
Lysosome biology in autophagy (Yim et al., Cell Discov)
2019/12/31
The ATG conjugation systems in autophagy (Mizushima, Curr Opin Cell Biol)
2019/10/06
Diverse cellular roles of autophagy (Morishita et al., Annu Rev Cell Dev Biol)
2019/09/15
The ubiquitin E2 enzyme UBE2QL1 mediates lysophagy (Mizushima, EMBO Rep)
Mizushima Lab