本文へスキップ
.

研究業績

最新のリストはこちらから
https://scholar.google.co.jp/citations?hl=ja&user=4C4p5C8AAAAJ

2021

[208] T. Naito, K. Suzuki, J. Hirata, Y. Kamatani, K. Matsuda, T. Toda, Y. Okada, A deep learning method for HLA imputation and trans-ethnic MHC fine-mapping of type 1 diabetes, Nature communications, 12 (2021) 1639.

[207] O. Toyoshima, T. Nishizawa, K. Sekiba, T. Matsuno, R. Kondo, H. Watanabe, H. Suzuki, C. Tanikawa, K. Koike, K. Matsuda, A single nucleotide polymorphism in Prostate Stem Cell Antigen is associated with endoscopic grading in Kyoto classification of gastritis, J Clin Biochem Nutr, 68 (2021) 73-77.

[206] S. Kohsaka, M. Hirata, M. Ikegami, T. Ueno, S. Kojima, T. Sakai, K. Ito, N. Naka, K. Ogura, A. Kawai, S. Iwata, T. Okuma, T. Yonemoto, H. Kobayashi, Y. Suehara, H. Hiraga, T. Kawamoto, T. Motoi, Y. Oda, D. Matsubara, K. Matsuda, Y. Nishida, H. Mano, Comprehensive molecular and clinicopathological profiling of desmoid tumours, Eur J Cancer, 145 (2021) 109-120.

[205] B.M. Lin, K.E. Grinde, J.A. Brody, C.E. Breeze, L.M. Raffield, J.C. Mychaleckyj, T.A. Thornton, J.A. Perry, L.J. Baier, L. de Las Fuentes, X. Guo, B.D. Heavner, R.L. Hanson, Y.J. Hung, H. Qian, C.A. Hsiung, S.J. Hwang, M.R. Irvin, D. Jain, T.N. Kelly, S. Kobes, L. Lange, J.P. Lash, Y. Li, X. Liu, X. Mi, S.K. Musani, G.J. Papanicolaou, A. Parsa, A.P. Reiner, S. Salimi, W.H. Sheu, A.R. Shuldiner, K.D. Taylor, A.V. Smith, J.A. Smith, A. Tin, D. Vaidya, R.B. Wallace, K. Yamamoto, S. Sakaue, K. Matsuda, Y. Kamatani, Y. Momozawa, L.R. Yanek, B.A. Young, W. Zhao, Y. Okada, G. Abecasis, B.M. Psaty, D.K. Arnett, E. Boerwinkle, J. Cai, I. Yii-Der Chen, A. Correa, L.A. Cupples, J. He, S.L. Kardia, C. Kooperberg, R.A. Mathias, B.D. Mitchell, D.A. Nickerson, S.T. Turner, R.S. Vasan, J.I. Rotter, D. Levy, H.J. Kramer, A. Kottgen, T.C. Nhlbi Trans-Omics For Precision Medicine, T.O.K.W. Group, S.S. Rich, D.Y. Lin, S.R. Browning, N. Franceschini, Whole genome sequence analyses of eGFR in 23,732 people representing multiple ancestries in the NHLBI trans-omics for precision medicine (TOPMed) consortium, EBioMedicine, 63 (2021) 103157.

[204] D.V. Conti, B.F. Darst, L.C. Moss, E.J. Saunders, X. Sheng, A. Chou, F.R. Schumacher, A.A.A. Olama, S. Benlloch, T. Dadaev, M.N. Brook, A. Sahimi, T.J. Hoffmann, A. Takahashi, K. Matsuda, Y. Momozawa, M. Fujita, K. Muir, A. Lophatananon, P. Wan, L. Le Marchand, L.R. Wilkens, V.L. Stevens, S.M. Gapstur, B.D. Carter, J. Schleutker, T.L.J. Tammela, C. Sipeky, A. Auvinen, G.G. Giles, M.C. Southey, R.J. MacInnis, C. Cybulski, D. Wokolorczyk, J. Lubinski, D.E. Neal, J.L. Donovan, F.C. Hamdy, R.M. Martin, B.G. Nordestgaard, S.F. Nielsen, M. Weischer, S.E. Bojesen, M.A. Roder, P. Iversen, J. Batra, S. Chambers, L. Moya, L. Horvath, J.A. Clements, W. Tilley, G.P. Risbridger, H. Gronberg, M. Aly, R. Szulkin, M. Eklund, T. Nordstrom, N. Pashayan, A.M. Dunning, M. Ghoussaini, R.C. Travis, T.J. Key, E. Riboli, J.Y. Park, T.A. Sellers, H.Y. Lin, D. Albanes, S.J. Weinstein, L.A. Mucci, E. Giovannucci, S. Lindstrom, P. Kraft, D.J. Hunter, K.L. Penney, C. Turman, C.M. Tangen, P.J. Goodman, I.M. Thompson, Jr., R.J. Hamilton, N.E. Fleshner, A. Finelli, M.E. Parent, J.L. Stanford, E.A. Ostrander, M.S. Geybels, S. Koutros, L.E.B. Freeman, M. Stampfer, A. Wolk, N. Hakansson, G.L. Andriole, R.N. Hoover, M.J. Machiela, K.D. Sorensen, M. Borre, W.J. Blot, W. Zheng, E.D. Yeboah, J.E. Mensah, Y.J. Lu, H.W. Zhang, N. Feng, X. Mao, Y. Wu, S.C. Zhao, Z. Sun, S.N. Thibodeau, S.K. McDonnell, D.J. Schaid, C.M.L. West, N. Burnet, G. Barnett, C. Maier, T. Schnoeller, M. Luedeke, A.S. Kibel, B.F. Drake, O. Cussenot, G. Cancel-Tassin, F. Menegaux, T. Truong, Y.A. Koudou, E.M. John, E.M. Grindedal, L. Maehle, K.T. Khaw, S.A. Ingles, M.C. Stern, A. Vega, A. Gomez-Caamano, L. Fachal, B.S. Rosenstein, S.L. Kerns, H. Ostrer, M.R. Teixeira, P. Paulo, A. Brandao, S. Watya, A. Lubwama, J.T. Bensen, E.T.H. Fontham, J. Mohler, J.A. Taylor, M. Kogevinas, J. Llorca, G. Castano-Vinyals, L. Cannon-Albright, C.C. Teerlink, C.D. Huff, S.S. Strom, L. Multigner, P. Blanchet, L. Brureau, R. Kaneva, C. Slavov, V. Mitev, R.J. Leach, B. Weaver, H. Brenner, K. Cuk, B. Holleczek, K.U. Saum, E.A. Klein, A.W. Hsing, R.A. Kittles, A.B. Murphy, C.J. Logothetis, J. Kim, S.L. Neuhausen, L. Steele, Y.C. Ding, W.B. Isaacs, B. Nemesure, A.J.M. Hennis, J. Carpten, H. Pandha, A. Michael, K. De Ruyck, G. De Meerleer, P. Ost, J. Xu, A. Razack, J. Lim, S.H. Teo, L.F. Newcomb, D.W. Lin, J.H. Fowke, C. Neslund-Dudas, B.A. Rybicki, M. Gamulin, D. Lessel, T. Kulis, N. Usmani, S. Singhal, M. Parliament, F. Claessens, S. Joniau, T. Van den Broeck, M. Gago-Dominguez, J.E. Castelao, M.E. Martinez, S. Larkin, P.A. Townsend, C. Aukim-Hastie, W.S. Bush, M.C. Aldrich, D.C. Crawford, S. Srivastava, J.C. Cullen, G. Petrovics, G. Casey, M.J. Roobol, G. Jenster, R.H.N. van Schaik, J.J. Hu, M. Sanderson, R. Varma, R. McKean-Cowdin, M. Torres, N. Mancuso, S.I. Berndt, S.K. Van Den Eeden, D.F. Easton, S.J. Chanock, M.B. Cook, F. Wiklund, H. Nakagawa, J.S. Witte, R.A. Eeles, Z. Kote-Jarai, C.A. Haiman, Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction, Nat Genet, 53 (2021) 65-75.

[203] M. Fujita, X. Liu, Y. Iwasaki, C. Terao, K. Mizukami, E. Kawakami, S. Takata, C. Inai, T. Aoi, M. Mizukoshi, K. Maejima, M. Hirata, Y. Murakami, Y. Kamatani, M. Kubo, K. Akagi, K. Matsuda, H. Nakagawa, Y. Momozawa, Population-based Screening for Hereditary Colorectal Cancer Variants in Japan, Clin Gastroenterol Hepatol, (2020).

[202] X. Yin, K. Kim, H. Suetsugu, S.Y. Bang, L. Wen, M. Koido, E. Ha, L. Liu, Y. Sakamoto, S. Jo, R.X. Leng, N. Otomo, V. Laurynenka, Y.C. Kwon, Y. Sheng, N. Sugano, M.Y. Hwang, W. Li, M. Mukai, K. Yoon, M. Cai, K. Ishigaki, W.T. Chung, H. Huang, D. Takahashi, S.S. Lee, M. Wang, K. Karino, S.C. Shim, X. Zheng, T. Miyamura, Y.M. Kang, D. Ye, J. Nakamura, C.H. Suh, Y. Tang, G. Motomura, Y.B. Park, H. Ding, T. Kuroda, J.Y. Choe, C. Li, H. Niiro, Y. Park, C. Shen, T. Miyamoto, G.Y. Ahn, W. Fei, T. Takeuchi, J.M. Shin, K. Li, Y. Kawaguchi, Y.K. Lee, Y. Wang, K. Amano, D.J. Park, W. Yang, Y. Tada, K. Yamaji, M. Shimizu, T. Atsumi, A. Suzuki, T. Sumida, Y. Okada, K. Matsuda, K. Matsuo, Y. Kochi, H. Japanese Research Committee on Idiopathic Osteonecrosis of the Femoral, L.C. Kottyan, M.T. Weirauch, S. Parameswaran, S. Eswar, H. Salim, X. Chen, K. Yamamoto, J.B. Harley, K. Ohmura, T.H. Kim, S. Yang, T. Yamamoto, B.J. Kim, N. Shen, S. Ikegawa, H.S. Lee, X. Zhang, C. Terao, Y. Cui, S.C. Bae, Meta-analysis of 208370 East Asians identifies 113 susceptibility loci for systemic lupus erythematosus, Ann Rheum Dis, (2020).

[201] T. Nishizawa, O. Toyoshima, R. Kondo, K. Sekiba, Y. Tsuji, H. Ebinuma, H. Suzuki, C. Tanikawa, K. Matsuda, K. Koike, The simplified Kyoto classification score is consistent with the ABC method of classification as a grading system for endoscopic gastritis, J Clin Biochem Nutr, 68 (2021) 101-104.

 

2020

 

[200] T. Amariuta, K. Ishigaki, H. Sugishita, T. Ohta, M. Koido, K.K. Dey, K. Matsuda, Y. Murakami, A.L. Price, E. Kawakami, C. Terao, S. Raychaudhuri, Improving the trans-ancestry portability of polygenic risk scores by prioritizing variants in predicted cell-type-specific regulatory elements, Nat Genet, 52 (2020) 1346-1354.

[199] H. Liu, X. Jiang, Q. Qiao, L. Chen, K. Matsuda, G. Jiang, T. Yu, Y. Wang, H. Lin, X. Liang, X. Cai, Association of circulating 25-Hydroxyvitamin D and its related genetic variations with hepatocellular carcinoma incidence and survival, Ann Transl Med, 8 (2020) 1080.

[198] T. Masuda, H. Ito, J. Hirata, S. Sakaue, Y. Ueda, T. Kimura, F. Takeuchi, Y. Murakami, K. Matsuda, K. Matsuo, Y. Okada, Fine Mapping of the Major Histocompatibility Complex Region and Association of the HLA-B*52:01 Allele With Cervical Cancer in Japanese Women, JAMA Netw Open, 3 (2020) e2023248.

[197] S. Koyama, K. Ito, C. Terao, M. Akiyama, M. Horikoshi, Y. Momozawa, H. Matsunaga, H. Ieki, K. Ozaki, Y. Onouchi, A. Takahashi, S. Nomura, H. Morita, H. Akazawa, C. Kim, J.S. Seo, K. Higasa, M. Iwasaki, T. Yamaji, N. Sawada, S. Tsugane, T. Koyama, H. Ikezaki, N. Takashima, K. Tanaka, K. Arisawa, K. Kuriki, M. Naito, K. Wakai, S. Suna, Y. Sakata, H. Sato, M. Hori, Y. Sakata, K. Matsuda, Y. Murakami, H. Aburatani, M. Kubo, F. Matsuda, Y. Kamatani, I. Komuro, Population-specific and trans-ancestry genome-wide analyses identify distinct and shared genetic risk loci for coronary artery disease, Nat Genet, 52 (2020) 1169-1177.

 

[196] O. Toyoshima, T. Nishizawa, S. Yoshida, Y. Sakaguchi, Y. Nakai, H. Watanabe, H. Suzuki, C. Tanikawa, K. Matsuda, K. Koike, Endoscopy-based Kyoto classification score of gastritis related to pathological topography of neutrophil activity, World J Gastroenterol, 26 (2020) 5146-5155.

[195] K. Mizukami, Y. Iwasaki, E. Kawakami, M. Hirata, Y. Kamatani, K. Matsuda, M. Endo, K. Sugano, T. Yoshida, Y. Murakami, H. Nakagawa, A.B. Spurdle, Y. Momozawa, Genetic characterization of pancreatic cancer patients and prediction of carrier status of germline pathogenic variants in cancer-predisposing genes, EBioMedicine, 60 (2020) 103033.

[194] D. Vuckovic, E.L. Bao, P. Akbari, C.A. Lareau, A. Mousas, T. Jiang, M.H. Chen, L.M. Raffield, M. Tardaguila, J.E. Huffman, S.C. Ritchie, K. Megy, H. Ponstingl, C.J. Penkett, P.K. Albers, E.M. Wigdor, S. Sakaue, A. Moscati, R. Manansala, K.S. Lo, H. Qian, M. Akiyama, T.M. Bartz, Y. Ben-Shlomo, A. Beswick, J. Bork-Jensen, E.P. Bottinger, J.A. Brody, F.J.A. van Rooij, K.N. Chitrala, P.W.F. Wilson, H. Choquet, J. Danesh, E. Di Angelantonio, N. Dimou, J. Ding, P. Elliott, T. Esko, M.K. Evans, S.B. Felix, J.S. Floyd, L. Broer, N. Grarup, M.H. Guo, Q. Guo, A. Greinacher, J. Haessler, T. Hansen, J.M.M. Howson, W. Huang, E. Jorgenson, T. Kacprowski, M. Kahonen, Y. Kamatani, M. Kanai, S. Karthikeyan, F. Koskeridis, L.A. Lange, T. Lehtimaki, A. Linneberg, Y. Liu, L.P. Lyytikainen, A. Manichaikul, K. Matsuda, K.L. Mohlke, N. Mononen, Y. Murakami, G.N. Nadkarni, K. Nikus, N. Pankratz, O. Pedersen, M. Preuss, B.M. Psaty, O.T. Raitakari, S.S. Rich, B.A.T. Rodriguez, J.D. Rosen, J.I. Rotter, P. Schubert, C.N. Spracklen, P. Surendran, H. Tang, J.C. Tardif, M. Ghanbari, U. Volker, H. Volzke, N.A. Watkins, S. Weiss, V.A.M.V. Program, N. Cai, K. Kundu, S.B. Watt, K. Walter, A.B. Zonderman, K. Cho, Y. Li, R.J.F. Loos, J.C. Knight, M. Georges, O. Stegle, E. Evangelou, Y. Okada, D.J. Roberts, M. Inouye, A.D. Johnson, P.L. Auer, W.J. Astle, A.P. Reiner, A.S. Butterworth, W.H. Ouwehand, G. Lettre, V.G. Sankaran, N. Soranzo, The Polygenic and Monogenic Basis of Blood Traits and Diseases, Cell, 182 (2020) 1214-1231 e1211.

[193] M.H. Chen, L.M. Raffield, A. Mousas, S. Sakaue, J.E. Huffman, A. Moscati, B. Trivedi, T. Jiang, P. Akbari, D. Vuckovic, E.L. Bao, X. Zhong, R. Manansala, V. Laplante, M. Chen, K.S. Lo, H. Qian, C.A. Lareau, M. Beaudoin, K.A. Hunt, M. Akiyama, T.M. Bartz, Y. Ben-Shlomo, A. Beswick, J. Bork-Jensen, E.P. Bottinger, J.A. Brody, F.J.A. van Rooij, K. Chitrala, K. Cho, H. Choquet, A. Correa, J. Danesh, E. Di Angelantonio, N. Dimou, J. Ding, P. Elliott, T. Esko, M.K. Evans, J.S. Floyd, L. Broer, N. Grarup, M.H. Guo, A. Greinacher, J. Haessler, T. Hansen, J.M.M. Howson, Q.Q. Huang, W. Huang, E. Jorgenson, T. Kacprowski, M. Kahonen, Y. Kamatani, M. Kanai, S. Karthikeyan, F. Koskeridis, L.A. Lange, T. Lehtimaki, M.M. Lerch, A. Linneberg, Y. Liu, L.P. Lyytikainen, A. Manichaikul, H.C. Martin, K. Matsuda, K.L. Mohlke, N. Mononen, Y. Murakami, G.N. Nadkarni, M. Nauck, K. Nikus, W.H. Ouwehand, N. Pankratz, O. Pedersen, M. Preuss, B.M. Psaty, O.T. Raitakari, D.J. Roberts, S.S. Rich, B.A.T. Rodriguez, J.D. Rosen, J.I. Rotter, P. Schubert, C.N. Spracklen, P. Surendran, H. Tang, J.C. Tardif, R.C. Trembath, M. Ghanbari, U. Volker, H. Volzke, N.A. Watkins, A.B. Zonderman, V.A.M.V. Program, P.W.F. Wilson, Y. Li, A.S. Butterworth, J.F. Gauchat, C.W.K. Chiang, B. Li, R.J.F. Loos, W.J. Astle, E. Evangelou, D.A. van Heel, V.G. Sankaran, Y. Okada, N. Soranzo, A.D. Johnson, A.P. Reiner, P.L. Auer, G. Lettre, Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations, Cell, 182 (2020) 1198-1213 e1114.

[192] X. Liu, S. Kosugi, R. Koide, Y. Kawamura, J. Ito, H. Miura, N. Matoba, M. Matsuzaki, M. Fujita, A.J. Kamada, H. Nakagawa, G. Tamiya, K. Matsuda, Y. Murakami, M. Kubo, A. Aswad, K. Sato, Y. Momozawa, J. Ohashi, C. Terao, T. Yoshikawa, N.F. Parrish, Y. Kamatani, Endogenization and excision of human herpesvirus 6 in human genomes, PLoS Genet, 16 (2020) e1008915.

[191] C. Terao, A. Suzuki, Y. Momozawa, M. Akiyama, K. Ishigaki, K. Yamamoto, K. Matsuda, Y. Murakami, S.A. McCarroll, M. Kubo, P.R. Loh, Y. Kamatani, Chromosomal alterations among age-related haematopoietic clones in Japan, Nature, 584 (2020) 130-135.

[190] Y. Lin, M. Nakatochi, Y. Hosono, H. Ito, Y. Kamatani, A. Inoko, H. Sakamoto, F. Kinoshita, Y. Kobayashi, H. Ishii, M. Ozaka, T. Sasaki, M. Matsuyama, N. Sasahira, M. Morimoto, S. Kobayashi, T. Fukushima, M. Ueno, S. Ohkawa, N. Egawa, S. Kuruma, M. Mori, H. Nakao, Y. Adachi, M. Okuda, T. Osaki, S. Kamiya, C. Wang, K. Hara, Y. Shimizu, T. Miyamoto, Y. Hayashi, H. Ebi, T. Kohmoto, I. Imoto, Y. Kasugai, Y. Murakami, M. Akiyama, K. Ishigaki, K. Matsuda, M. Hirata, K. Shimada, T. Okusaka, T. Kawaguchi, M. Takahashi, Y. Watanabe, K. Kuriki, A. Kadota, R. Okada, H. Mikami, T. Takezaki, S. Suzuki, T. Yamaji, M. Iwasaki, N. Sawada, A. Goto, K. Kinoshita, N. Fuse, F. Katsuoka, A. Shimizu, S.S. Nishizuka, K. Tanno, K. Suzuki, Y. Okada, M. Horikoshi, T. Yamauchi, T. Kadowaki, H. Yu, J. Zhong, L.T. Amundadottir, Y. Doki, H. Ishii, H. Eguchi, D. Bogumil, C.A. Haiman, L. Le Marchand, M. Mori, H. Risch, V.W. Setiawan, S. Tsugane, K. Wakai, T. Yoshida, F. Matsuda, M. Kubo, S. Kikuchi, K. Matsuo, Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer, Nature communications, 11 (2020) 3175.

[189] K. Ishigaki, M. Akiyama, M. Kanai, A. Takahashi, E. Kawakami, H. Sugishita, S. Sakaue, N. Matoba, S.K. Low, Y. Okada, C. Terao, T. Amariuta, S. Gazal, Y. Kochi, M. Horikoshi, K. Suzuki, K. Ito, S. Koyama, K. Ozaki, S. Niida, Y. Sakata, Y. Sakata, T. Kohno, K. Shiraishi, Y. Momozawa, M. Hirata, K. Matsuda, M. Ikeda, N. Iwata, S. Ikegawa, I. Kou, T. Tanaka, H. Nakagawa, A. Suzuki, T. Hirota, M. Tamari, K. Chayama, D. Miki, M. Mori, S. Nagayama, Y. Daigo, Y. Miki, T. Katagiri, O. Ogawa, W. Obara, H. Ito, T. Yoshida, I. Imoto, T. Takahashi, C. Tanikawa, T. Suzuki, N. Sinozaki, S. Minami, H. Yamaguchi, S. Asai, Y. Takahashi, K. Yamaji, K. Takahashi, T. Fujioka, R. Takata, H. Yanai, A. Masumoto, Y. Koretsune, H. Kutsumi, M. Higashiyama, S. Murayama, N. Minegishi, K. Suzuki, K. Tanno, A. Shimizu, T. Yamaji, M. Iwasaki, N. Sawada, H. Uemura, K. Tanaka, M. Naito, M. Sasaki, K. Wakai, S. Tsugane, M. Yamamoto, K. Yamamoto, Y. Murakami, Y. Nakamura, S. Raychaudhuri, J. Inazawa, T. Yamauchi, T. Kadowaki, M. Kubo, Y. Kamatani, Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases, Nat Genet, 52 (2020) 669-679.

[188] H. Matsunaga, K. Ito, M. Akiyama, A. Takahashi, S. Koyama, S. Nomura, H. Ieki, K. Ozaki, Y. Onouchi, S. Sakaue, S. Suna, S. Ogishima, M. Yamamoto, A. Hozawa, M. Satoh, M. Sasaki, T. Yamaji, N. Sawada, M. Iwasaki, S. Tsugane, K. Tanaka, K. Arisawa, H. Ikezaki, N. Takashima, M. Naito, K. Wakai, H. Tanaka, Y. Sakata, H. Morita, Y. Sakata, K. Matsuda, Y. Murakami, H. Akazawa, M. Kubo, Y. Kamatani, I. Komuro, Transethnic Meta-Analysis of Genome-Wide Association Studies Identifies Three New Loci and Characterizes Population-Specific Differences for Coronary Artery Disease, Circ Genom Precis Med, 13 (2020) e002670.

[187] S. Sakaue, M. Kanai, J. Karjalainen, M. Akiyama, M. Kurki, N. Matoba, A. Takahashi, M. Hirata, M. Kubo, K. Matsuda, Y. Murakami, FinnGen, M.J. Daly, Y. Kamatani, Y. Okada, Trans-biobank analysis with 676,000 individuals elucidates the association of polygenic risk scores of complex traits with human lifespan, Nature medicine, 26 (2020) 542-548.

[186] S. Sakaue, J. Hirata, M. Kanai, K. Suzuki, M. Akiyama, C. Lai Too, T. Arayssi, M. Hammoudeh, S. Al Emadi, B.K. Masri, H. Halabi, H. Badsha, I.W. Uthman, R. Saxena, L. Padyukov, M. Hirata, K. Matsuda, Y. Murakami, Y. Kamatani, Y. Okada, Dimensionality reduction reveals fine-scale structure in the Japanese population with consequences for polygenic risk prediction, Nature communications, 11 (2020) 1569.

[185] J.N. Curry, M. Saurette, M. Askari, L. Pei, M.B. Filla, M.R. Beggs, P.S. Rowe, T. Fields, A.J. Sommer, C. Tanikawa, Y. Kamatani, A.P. Evan, M. Totonchi, R.T. Alexander, K. Matsuda, A.S. Yu, Claudin-2 deficiency associates with hypercalciuria in mice and human kidney stone disease, J Clin Invest, (2020).

[184] K. Yamamoto, S. Sakaue, K. Matsuda, Y. Murakami, Y. Kamatani, K. Ozono, Y. Momozawa, Y. Okada, Genetic and phenotypic landscape of the mitochondrial genome in the Japanese population, Commun Biol, 3 (2020) 104.

[183] X. Shu, J. Long, Q. Cai, S.S. Kweon, J.Y. Choi, M. Kubo, S.K. Park, M.K. Bolla, J. Dennis, Q. Wang, Y. Yang, J. Shi, X. Guo, B. Li, R. Tao, K.J. Aronson, K.Y.K. Chan, T.L. Chan, Y.T. Gao, M. Hartman, W. Kee Ho, H. Ito, M. Iwasaki, H. Iwata, E.M. John, Y. Kasuga, U. Soon Khoo, M.K. Kim, S.Y. Kong, A.W. Kurian, A. Kwong, E.S. Lee, J. Li, A. Lophatananon, S.K. Low, S. Mariapun, K. Matsuda, K. Matsuo, K. Muir, D.Y. Noh, B. Park, M.H. Park, C.Y. Shen, M.H. Shin, J.J. Spinelli, A. Takahashi, C. Tseng, S. Tsugane, A.H. Wu, Y.B. Xiang, T. Yamaji, Y. Zheng, R.L. Milne, A.M. Dunning, P.D.P. Pharoah, M. Garcia-Closas, S.H. Teo, X.O. Shu, D. Kang, D.F. Easton, J. Simard, W. Zheng, Identification of novel breast cancer susceptibility loci in meta-analyses conducted among Asian and European descendants, Nature communications, 11 (2020) 1217.

[182] K. Sakai, C. Tanikawa, A. Hirasawa, T. Chiyoda, W. Yamagami, F. Kataoka, N. Susumu, C. Terao, Y. Kamatani, A. Takahashi, Y. Momozawa, M. Hirata, M. Kubo, N. Fuse, T. Takai-Igarashi, A. Shimizu, A. Fukushima, A. Kadota, K. Arisawa, H. Ikezaki, K. Wakai, T. Yamaji, N. Sawada, M. Iwasaki, S. Tsugane, D. Aoki, K. Matsuda, Identification of a novel uterine leiomyoma GWAS locus in a Japanese population, Scientific reports, 10 (2020) 1197.

[181] N. Matoba, M. Akiyama, K. Ishigaki, M. Kanai, A. Takahashi, Y. Momozawa, S. Ikegawa, M. Ikeda, N. Iwata, M. Hirata, K. Matsuda, Y. Murakami, M. Kubo, Y. Kamatani, Y. Okada, GWAS of 165,084 Japanese individuals identified nine loci associated with dietary habits, Nat Hum Behav, (2020).

[180] Y. Yasumizu, S. Sakaue, T. Konuma, K. Suzuki, K. Matsuda, Y. Murakami, M. Kubo, P.F. Palamara, Y. Kamatani, Y. Okada, Genome-wide natural selection signatures are linked to genetic risk of modern phenotypes in the Japanese population, Mol Biol Evol, (2020).

 

2019

 

[179] M. Hirata, N. Asano, K. Katayama, A. Yoshida, Y. Tsuda, M. Sekimizu, S. Mitani, E. Kobayashi, M. Komiyama, H. Fujimoto, T. Goto, Y. Iwamoto, N. Naka, S. Iwata, Y. Nishida, T. Hiruma, H. Hiraga, H. Kawano, T. Motoi, Y. Oda, D. Matsubara, M. Fujita, T. Shibata, H. Nakagawa, R. Nakayama, T. Kondo, S. Imoto, S. Miyano, A. Kawai, R. Yamaguchi, H. Ichikawa, K. Matsuda, Integrated exome and RNA sequencing of dedifferentiated liposarcoma, Nature communications, 10 (2019) 5683.

[178] S.K. Low, Y.M. Chin, H. Ito, K. Matsuo, C. Tanikawa, K. Matsuda, H. Saito, M. Sakurai-Yageta, N. Nakaya, A. Shimizu, S.S. Nishizuka, T. Yamaji, N. Sawada, M. Iwasaki, S. Tsugane, T. Takezaki, S. Suzuki, M. Naito, K. Wakai, Y. Kamatani, Y. Momozawa, Y. Murakami, J. Inazawa, Y. Nakamura, M. Kubo, T. Katagiri, Y. Miki, Identification of two novel breast cancer loci through large-scale genome-wide association study in the Japanese population, Scientific reports, 9 (2019) 17332.

[177] S.A. Howles, A. Wiberg, M. Goldsworthy, A.L. Bayliss, A.K. Gluck, M. Ng, E. Grout, C. Tanikawa, Y. Kamatani, C. Terao, A. Takahashi, M. Kubo, K. Matsuda, R.V. Thakker, B.W. Turney, D. Furniss, Genetic variants of calcium and vitamin D metabolism in kidney stone disease, Nature communications, 10 (2019) 5175.

[176] D.W. Clark, Y. Okada, K.H.S. Moore, D. Mason, N. Pirastu, I. Gandin, H. Mattsson, C.L.K. Barnes, K. Lin, J.H. Zhao, P. Deelen, R. Rohde, C. Schurmann, X. Guo, F. Giulianini, W. Zhang, C. Medina-Gomez, R. Karlsson, Y. Bao, T.M. Bartz, C. Baumbach, G. Biino, M.J. Bixley, M. Brumat, J.F. Chai, T. Corre, D.L. Cousminer, A.M. Dekker, D.A. Eccles, K.R. van Eijk, C. Fuchsberger, H. Gao, M. Germain, S.D. Gordon, H.G. de Haan, S.E. Harris, E. Hofer, A. Huerta-Chagoya, C. Igartua, I.E. Jansen, Y. Jia, T. Kacprowski, T. Karlsson, M.E. Kleber, S.A. Li, R. Li-Gao, A. Mahajan, K. Matsuda, K. Meidtner, W. Meng, M.E. Montasser, P.J. van der Most, M. Munz, T. Nutile, T. Palviainen, G. Prasad, R.B. Prasad, T.D.S. Priyanka, F. Rizzi, E. Salvi, B.R. Sapkota, D. Shriner, L. Skotte, M.C. Smart, A.V. Smith, A. van der Spek, C.N. Spracklen, R.J. Strawbridge, S.M. Tajuddin, S. Trompet, C. Turman, N. Verweij, C. Viberti, L. Wang, H.R. Warren, R.E. Wootton, L.R. Yanek, J. Yao, N.A. Yousri, W. Zhao, A.A. Adeyemo, S. Afaq, C.A. Aguilar-Salinas, M. Akiyama, M.L. Albert, M.A. Allison, M. Alver, T. Aung, F. Azizi, A.R. Bentley, H. Boeing, E. Boerwinkle, J.B. Borja, G.J. de Borst, E.P. Bottinger, L. Broer, H. Campbell, S. Chanock, M.L. Chee, G. Chen, Y.I. Chen, Z. Chen, Y.F. Chiu, M. Cocca, F.S. Collins, M.P. Concas, J. Corley, G. Cugliari, R.M. van Dam, A. Damulina, M.S. Daneshpour, F.R. Day, G.E. Delgado, K. Dhana, A.S.F. Doney, M. Dorr, A.P. Doumatey, N. Dzimiri, S.S. Ebenesersdottir, J. Elliott, P. Elliott, R. Ewert, J.F. Felix, K. Fischer, B.I. Freedman, G. Girotto, A. Goel, M. Gogele, M.O. Goodarzi, M. Graff, E. Granot-Hershkovitz, F. Grodstein, S. Guarrera, D.F. Gudbjartsson, K. Guity, B. Gunnarsson, Y. Guo, S.P. Hagenaars, C.A. Haiman, A. Halevy, T.B. Harris, M. Hedayati, D.A. van Heel, M. Hirata, I. Hofer, C.A. Hsiung, J. Huang, Y.J. Hung, M.A. Ikram, A. Jagadeesan, P. Jousilahti, Y. Kamatani, M. Kanai, N.D. Kerrison, T. Kessler, K.T. Khaw, C.C. Khor, D.P.V. de Kleijn, W.P. Koh, I. Kolcic, P. Kraft, B.K. Kramer, Z. Kutalik, J. Kuusisto, C. Langenberg, L.J. Launer, D.A. Lawlor, I.T. Lee, W.J. Lee, M.M. Lerch, L. Li, J. Liu, M. Loh, S.J. London, S. Loomis, Y. Lu, J. Luan, R. Magi, A.W. Manichaikul, P. Manunta, G. Masson, N. Matoba, X.W. Mei, C. Meisinger, T. Meitinger, M. Mezzavilla, L. Milani, I.Y. Millwood, Y. Momozawa, A. Moore, P.E. Morange, H. Moreno-Macias, T.A. Mori, A.C. Morrison, T. Muka, Y. Murakami, A.D. Murray, R. de Mutsert, J.C. Mychaleckyj, M.A. Nalls, M. Nauck, M.J. Neville, I.M. Nolte, K.K. Ong, L. Orozco, S. Padmanabhan, G. Palsson, J.S. Pankow, C. Pattaro, A. Pattie, O. Polasek, N. Poulter, P.P. Pramstaller, L. Quintana-Murci, K. Raikkonen, S. Ralhan, D.C. Rao, W. van Rheenen, S.S. Rich, P.M. Ridker, C.A. Rietveld, A. Robino, F.J.A. van Rooij, D. Ruggiero, Y. Saba, C. Sabanayagam, M. Sabater-Lleal, C.F. Sala, V. Salomaa, K. Sandow, H. Schmidt, L.J. Scott, W.R. Scott, B. Sedaghati-Khayat, B. Sennblad, J. van Setten, P.J. Sever, W.H. Sheu, Y. Shi, S. Shrestha, S.R. Shukla, J.K. Sigurdsson, T.T. Sikka, J.R. Singh, B.H. Smith, A. Stancakova, A. Stanton, J.M. Starr, L. Stefansdottir, L. Straker, P. Sulem, G. Sveinbjornsson, M.A. Swertz, A.M. Taylor, K.D. Taylor, N. Terzikhan, Y.C. Tham, G. Thorleifsson, U. Thorsteinsdottir, A. Tillander, R.P. Tracy, T. Tusie-Luna, I. Tzoulaki, S. Vaccargiu, J. Vangipurapu, J.H. Veldink, V. Vitart, U. Volker, E. Vuoksimaa, S.M. Wakil, M. Waldenberger, G.S. Wander, Y.X. Wang, N.J. Wareham, S. Wild, C.S. Yajnik, J.M. Yuan, L. Zeng, L. Zhang, J. Zhou, N. Amin, F.W. Asselbergs, S.J.L. Bakker, D.M. Becker, B. Lehne, D.A. Bennett, L.H. van den Berg, S.I. Berndt, D. Bharadwaj, L.F. Bielak, M. Bochud, M. Boehnke, C. Bouchard, J.P. Bradfield, J.A. Brody, A. Campbell, S. Carmi, M.J. Caulfield, D. Cesarini, J.C. Chambers, G.R. Chandak, C.Y. Cheng, M. Ciullo, M. Cornelis, D. Cusi, G.D. Smith, I.J. Deary, R. Dorajoo, C.M. van Duijn, D. Ellinghaus, J. Erdmann, J.G. Eriksson, E. Evangelou, M.K. Evans, J.D. Faul, B. Feenstra, M. Feitosa, S. Foisy, A. Franke, Y. Friedlander, P. Gasparini, C. Gieger, C. Gonzalez, P. Goyette, S.F.A. Grant, L.R. Griffiths, L. Groop, V. Gudnason, U. Gyllensten, H. Hakonarson, A. Hamsten, P. van der Harst, C.K. Heng, A.A. Hicks, H. Hochner, H. Huikuri, S.C. Hunt, V.W.V. Jaddoe, P.L. De Jager, M. Johannesson, A. Johansson, J.B. Jonas, J.W. Jukema, J. Junttila, J. Kaprio, S.L.R. Kardia, F. Karpe, M. Kumari, M. Laakso, S.W. van der Laan, J. Lahti, M. Laudes, R.A. Lea, W. Lieb, T. Lumley, N.G. Martin, W. Marz, G. Matullo, M.I. McCarthy, S.E. Medland, T.R. Merriman, A. Metspalu, B.F. Meyer, K.L. Mohlke, G.W. Montgomery, D. Mook-Kanamori, P.B. Munroe, K.E. North, D.R. Nyholt, R. O'Connell J, C. Ober, A.J. Oldehinkel, W. Palmas, C. Palmer, G.G. Pasterkamp, E. Patin, C.E. Pennell, L. Perusse, P.A. Peyser, M. Pirastu, T.J.C. Polderman, D.J. Porteous, D. Posthuma, B.M. Psaty, J.D. Rioux, F. Rivadeneira, C. Rotimi, J.I. Rotter, I. Rudan, H.M. Den Ruijter, D.K. Sanghera, N. Sattar, R. Schmidt, M.B. Schulze, H. Schunkert, R.A. Scott, A.R. Shuldiner, X. Sim, N. Small, J.A. Smith, N. Sotoodehnia, E.S. Tai, A. Teumer, N.J. Timpson, D. Toniolo, D.A. Tregouet, T. Tuomi, P. Vollenweider, C.A. Wang, D.R. Weir, J.B. Whitfield, C. Wijmenga, T.Y. Wong, J. Wright, J. Yang, L. Yu, B.S. Zemel, A.B. Zonderman, M. Perola, P.K.E. Magnusson, A.G. Uitterlinden, J.S. Kooner, D.I. Chasman, R.J.F. Loos, N. Franceschini, L. Franke, C.S. Haley, C. Hayward, R.G. Walters, J.R.B. Perry, T. Esko, A. Helgason, K. Stefansson, P.K. Joshi, M. Kubo, J.F. Wilson, Associations of autozygosity with a broad range of human phenotypes, Nature communications, 10 (2019) 4957.

[175] Y. Lu, S.S. Kweon, Q. Cai, C. Tanikawa, X.O. Shu, W.H. Jia, Y.B. Xiang, J.R. Huyghe, T.A. Harrison, J. Kim, A. Shin, D.H. Kim, K. Matsuo, S.H. Jee, X. Guo, W. Wen, J. Shi, B. Li, N. Wang, M.H. Shin, H.L. Li, Z.F. Ren, J. Hwan Oh, I. Oze, Y.O. Ahn, K.J. Jung, J. Gao, Y.T. Gao, Z.Z. Pan, Y. Kamatani, A.T. Chan, A. Gsur, J. Hampe, L. Le Marchand, L. Li, A. Lindblom, V. Moreno, P.A. Newcomb, K. Offit, P.D.P. Pharoah, F.J.B. van Duijnhoven, B. Van Guelpen, P.E. Vodicka, S.J. Weinstein, A. Wolk, A.H. Wu, L. Hsu, Y.X. Zeng, J. Long, U. Peters, K. Matsuda, W. Zheng, Identification of novel loci and new risk variant in known loci for colorectal cancer risk in East Asians, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, (2019).

[174] Y. Hayashi, S. Goyama, X. Liu, M. Tamura, S. Asada, Y. Tanaka, T. Fukuyama, M. Wunderlich, E. O'Brien, B. Mizukawa, S. Yamazaki, A. Matsumoto, S. Yamasaki, T. Shibata, K. Matsuda, G. Sashida, H. Takizawa, T. Kitamura, Antitumor immunity augments the therapeutic effects of p53 activation on acute myeloid leukemia, Nature communications, 10 (2019) 4869.

[173] C. Terao, Y. Momozawa, K. Ishigaki, E. Kawakami, M. Akiyama, P.R. Loh, G. Genovese, H. Sugishita, T. Ohta, M. Hirata, J.R.B. Perry, K. Matsuda, Y. Murakami, M. Kubo, Y. Kamatani, GWAS of mosaic loss of chromosome Y highlights genetic effects on blood cell differentiation, Nature communications, 10 (2019) 4719.

[172] A. Tin, J. Marten, V.L. Halperin Kuhns, Y. Li, M. Wuttke, H. Kirsten, K.B. Sieber, C. Qiu, M. Gorski, Z. Yu, A. Giri, G. Sveinbjornsson, M. Li, A.Y. Chu, A. Hoppmann, L.J. O'Connor, B. Prins, T. Nutile, D. Noce, M. Akiyama, M. Cocca, S. Ghasemi, P.J. van der Most, K. Horn, Y. Xu, C. Fuchsberger, S. Sedaghat, S. Afaq, N. Amin, J. Arnlov, S.J.L. Bakker, N. Bansal, D. Baptista, S. Bergmann, M.L. Biggs, G. Biino, E. Boerwinkle, E.P. Bottinger, T.S. Boutin, M. Brumat, R. Burkhardt, E. Campana, A. Campbell, H. Campbell, R.J. Carroll, E. Catamo, J.C. Chambers, M. Ciullo, M.P. Concas, J. Coresh, T. Corre, D. Cusi, S.C. Felicita, M.H. de Borst, A. De Grandi, R. de Mutsert, A.P.J. de Vries, G. Delgado, A. Demirkan, O. Devuyst, K. Dittrich, K.U. Eckardt, G. Ehret, K. Endlich, M.K. Evans, R.T. Gansevoort, P. Gasparini, V. Giedraitis, C. Gieger, G. Girotto, M. Gogele, S.D. Gordon, D.F. Gudbjartsson, V. Gudnason, S. German Chronic Kidney Disease, T. Haller, P. Hamet, T.B. Harris, C. Hayward, A.A. Hicks, E. Hofer, H. Holm, W. Huang, N. Hutri-Kahonen, S.J. Hwang, M.A. Ikram, R.M. Lewis, E. Ingelsson, J. Jakobsdottir, I. Jonsdottir, H. Jonsson, P.K. Joshi, N.S. Josyula, B. Jung, M. Kahonen, Y. Kamatani, M. Kanai, S.M. Kerr, W. Kiess, M.E. Kleber, W. Koenig, J.S. Kooner, A. Korner, P. Kovacs, B.K. Kramer, F. Kronenberg, M. Kubo, B. Kuhnel, M. La Bianca, L.A. Lange, B. Lehne, T. Lehtimaki, S. Lifelines Cohort, J. Liu, M. Loeffler, R.J.F. Loos, L.P. Lyytikainen, R. Magi, A. Mahajan, N.G. Martin, W. Marz, D. Mascalzoni, K. Matsuda, C. Meisinger, T. Meitinger, A. Metspalu, Y. Milaneschi, V.A.M.V. Program, C.J. O'Donnell, O.D. Wilson, J.M. Gaziano, P.P. Mishra, K.L. Mohlke, N. Mononen, G.W. Montgomery, D.O. Mook-Kanamori, M. Muller-Nurasyid, G.N. Nadkarni, M.A. Nalls, M. Nauck, K. Nikus, B. Ning, I.M. Nolte, R. Noordam, J.R. O'Connell, I. Olafsson, S. Padmanabhan, B. Penninx, T. Perls, A. Peters, M. Pirastu, N. Pirastu, G. Pistis, O. Polasek, B. Ponte, D.J. Porteous, T. Poulain, M.H. Preuss, T.J. Rabelink, L.M. Raffield, O.T. Raitakari, R. Rettig, M. Rheinberger, K.M. Rice, F. Rizzi, A. Robino, I. Rudan, A. Krajcoviechova, R. Cifkova, R. Rueedi, D. Ruggiero, K.A. Ryan, Y. Saba, E. Salvi, H. Schmidt, R. Schmidt, C.M. Shaffer, A.V. Smith, B.H. Smith, C.N. Spracklen, K. Strauch, M. Stumvoll, P. Sulem, S.M. Tajuddin, A. Teren, J. Thiery, C.H.L. Thio, U. Thorsteinsdottir, D. Toniolo, A. Tonjes, J. Tremblay, A.G. Uitterlinden, S. Vaccargiu, P. van der Harst, C.M. van Duijn, N. Verweij, U. Volker, P. Vollenweider, G. Waeber, M. Waldenberger, J.B. Whitfield, S.H. Wild, J.F. Wilson, Q. Yang, W. Zhang, A.B. Zonderman, M. Bochud, J.G. Wilson, S.A. Pendergrass, K. Ho, A. Parsa, P.P. Pramstaller, B.M. Psaty, C.A. Boger, H. Snieder, A.S. Butterworth, Y. Okada, T.L. Edwards, K. Stefansson, K. Susztak, M. Scholz, I.M. Heid, A.M. Hung, A. Teumer, C. Pattaro, O.M. Woodward, V. Vitart, A. Kottgen, Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels, Nat Genet, 51 (2019) 1459-1474.

[171] M. Akiyama, K. Ishigaki, S. Sakaue, Y. Momozawa, M. Horikoshi, M. Hirata, K. Matsuda, S. Ikegawa, A. Takahashi, M. Kanai, S. Suzuki, D. Matsui, M. Naito, T. Yamaji, M. Iwasaki, N. Sawada, K. Tanno, M. Sasaki, A. Hozawa, N. Minegishi, K. Wakai, S. Tsugane, A. Shimizu, M. Yamamoto, Y. Okada, Y. Murakami, M. Kubo, Y. Kamatani, Characterizing rare and low-frequency height-associated variants in the Japanese population, Nature communications, 10 (2019) 4393.

[170] R. Takata, A. Takahashi, M. Fujita, Y. Momozawa, E.J. Saunders, H. Yamada, K. Maejima, K. Nakano, Y. Nishida, A. Hishida, K. Matsuo, K. Wakai, T. Yamaji, N. Sawada, M. Iwasaki, S. Tsugane, M. Sasaki, A. Shimizu, K. Tanno, N. Minegishi, K. Suzuki, K. Matsuda, M. Kubo, J. Inazawa, S. Egawa, C.A. Haiman, O. Ogawa, W. Obara, Y. Kamatani, S. Akamatsu, H. Nakagawa, 12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population, Nature communications, 10 (2019) 4422.

[169] S. Sakaue, M. Akiyama, M. Hirata, K. Matsuda, Y. Murakami, M. Kubo, Y. Kamatani, Y. Okada, Functional variants in ADH1B and ALDH2 are non-additively associated with all-cause mortality in Japanese population, Eur J Hum Genet, (2019).

[168] T. Masuda, S.K. Low, M. Akiyama, M. Hirata, Y. Ueda, K. Matsuda, T. Kimura, Y. Murakami, M. Kubo, Y. Kamatani, Y. Okada, GWAS of five gynecologic diseases and cross-trait analysis in Japanese, Eur J Hum Genet, (2019).

[167] Y. Momozawa, Y. Iwasaki, M. Hirata, X. Liu, Y. Kamatani, A. Takahashi, K. Sugano, T. Yoshida, Y. Murakami, K. Matsuda, H. Nakagawa, A.B. Spurdle, M. Kubo, Germline pathogenic variants in 7,636 Japanese patients with prostate cancer and 12,366 controls, J Natl Cancer Inst, (2019).

[166] M. Wuttke, Y. Li, M. Li, K.B. Sieber, M.F. Feitosa, M. Gorski, A. Tin, L. Wang, A.Y. Chu, A. Hoppmann, H. Kirsten, A. Giri, J.F. Chai, G. Sveinbjornsson, B.O. Tayo, T. Nutile, C. Fuchsberger, J. Marten, M. Cocca, S. Ghasemi, Y. Xu, K. Horn, D. Noce, P.J. van der Most, S. Sedaghat, Z. Yu, M. Akiyama, S. Afaq, T.S. Ahluwalia, P. Almgren, N. Amin, J. Arnlov, S.J.L. Bakker, N. Bansal, D. Baptista, S. Bergmann, M.L. Biggs, G. Biino, M. Boehnke, E. Boerwinkle, M. Boissel, E.P. Bottinger, T.S. Boutin, H. Brenner, M. Brumat, R. Burkhardt, A.S. Butterworth, E. Campana, A. Campbell, H. Campbell, M. Canouil, R.J. Carroll, E. Catamo, J.C. Chambers, M.L. Chee, M.L. Chee, X. Chen, C.Y. Cheng, Y. Cheng, K. Christensen, R. Cifkova, M. Ciullo, M.P. Concas, J.P. Cook, J. Coresh, T. Corre, C.F. Sala, D. Cusi, J. Danesh, E.W. Daw, M.H. de Borst, A. De Grandi, R. de Mutsert, A.P.J. de Vries, F. Degenhardt, G. Delgado, A. Demirkan, E. Di Angelantonio, K. Dittrich, J. Divers, R. Dorajoo, K.U. Eckardt, G. Ehret, P. Elliott, K. Endlich, M.K. Evans, J.F. Felix, V.H.X. Foo, O.H. Franco, A. Franke, B.I. Freedman, S. Freitag-Wolf, Y. Friedlander, P. Froguel, R.T. Gansevoort, H. Gao, P. Gasparini, J.M. Gaziano, V. Giedraitis, C. Gieger, G. Girotto, F. Giulianini, M. Gogele, S.D. Gordon, D.F. Gudbjartsson, V. Gudnason, T. Haller, P. Hamet, T.B. Harris, C.A. Hartman, C. Hayward, J.N. Hellwege, C.K. Heng, A.A. Hicks, E. Hofer, W. Huang, N. Hutri-Kahonen, S.J. Hwang, M.A. Ikram, O.S. Indridason, E. Ingelsson, M. Ising, V.W.V. Jaddoe, J. Jakobsdottir, J.B. Jonas, P.K. Joshi, N.S. Josyula, B. Jung, M. Kahonen, Y. Kamatani, C.M. Kammerer, M. Kanai, M. Kastarinen, S.M. Kerr, C.C. Khor, W. Kiess, M.E. Kleber, W. Koenig, J.S. Kooner, A. Korner, P. Kovacs, A.T. Kraja, A. Krajcoviechova, H. Kramer, B.K. Kramer, F. Kronenberg, M. Kubo, B. Kuhnel, M. Kuokkanen, J. Kuusisto, M. La Bianca, M. Laakso, L.A. Lange, C.D. Langefeld, J.J. Lee, B. Lehne, T. Lehtimaki, W. Lieb, S. Lifelines Cohort, S.C. Lim, L. Lind, C.M. Lindgren, J. Liu, J. Liu, M. Loeffler, R.J.F. Loos, S. Lucae, M.A. Lukas, L.P. Lyytikainen, R. Magi, P.K.E. Magnusson, A. Mahajan, N.G. Martin, J. Martins, W. Marz, D. Mascalzoni, K. Matsuda, C. Meisinger, T. Meitinger, O. Melander, A. Metspalu, E.K. Mikaelsdottir, Y. Milaneschi, K. Miliku, P.P. Mishra, V.A.M.V. Program, K.L. Mohlke, N. Mononen, G.W. Montgomery, D.O. Mook-Kanamori, J.C. Mychaleckyj, G.N. Nadkarni, M.A. Nalls, M. Nauck, K. Nikus, B. Ning, I.M. Nolte, R. Noordam, J. O'Connell, M.L. O'Donoghue, I. Olafsson, A.J. Oldehinkel, M. Orho-Melander, W.H. Ouwehand, S. Padmanabhan, N.D. Palmer, R. Palsson, B. Penninx, T. Perls, M. Perola, M. Pirastu, N. Pirastu, G. Pistis, A.I. Podgornaia, O. Polasek, B. Ponte, D.J. Porteous, T. Poulain, P.P. Pramstaller, M.H. Preuss, B.P. Prins, M.A. Province, T.J. Rabelink, L.M. Raffield, O.T. Raitakari, D.F. Reilly, R. Rettig, M. Rheinberger, K.M. Rice, P.M. Ridker, F. Rivadeneira, F. Rizzi, D.J. Roberts, A. Robino, P. Rossing, I. Rudan, R. Rueedi, D. Ruggiero, K.A. Ryan, Y. Saba, C. Sabanayagam, V. Salomaa, E. Salvi, K.U. Saum, H. Schmidt, R. Schmidt, B. Schottker, C.A. Schulz, N. Schupf, C.M. Shaffer, Y. Shi, A.V. Smith, B.H. Smith, N. Soranzo, C.N. Spracklen, K. Strauch, H.M. Stringham, M. Stumvoll, P.O. Svensson, S. Szymczak, E.S. Tai, S.M. Tajuddin, N.Y.Q. Tan, K.D. Taylor, A. Teren, Y.C. Tham, J. Thiery, C.H.L. Thio, H. Thomsen, G. Thorleifsson, D. Toniolo, A. Tonjes, J. Tremblay, I. Tzoulaki, A.G. Uitterlinden, S. Vaccargiu, R.M. van Dam, P. van der Harst, C.M. van Duijn, D.R. Velez Edward, N. Verweij, S. Vogelezang, U. Volker, P. Vollenweider, G. Waeber, M. Waldenberger, L. Wallentin, Y.X. Wang, C. Wang, D.M. Waterworth, W. Bin Wei, H. White, J.B. Whitfield, S.H. Wild, J.F. Wilson, M.K. Wojczynski, C. Wong, T.Y. Wong, L. Xu, Q. Yang, M. Yasuda, L.M. Yerges-Armstrong, W. Zhang, A.B. Zonderman, J.I. Rotter, M. Bochud, B.M. Psaty, V. Vitart, J.G. Wilson, A. Dehghan, A. Parsa, D.I. Chasman, K. Ho, A.P. Morris, O. Devuyst, S. Akilesh, S.A. Pendergrass, X. Sim, C.A. Boger, Y. Okada, T.L. Edwards, H. Snieder, K. Stefansson, A.M. Hung, I.M. Heid, M. Scholz, A. Teumer, A. Kottgen, C. Pattaro, A catalog of genetic loci associated with kidney function from analyses of a million individuals, Nat Genet, 51 (2019) 957-972.

[165] Y.J. Sung, L. de Las Fuentes, T.W. Winkler, D.I. Chasman, A.R. Bentley, A.T. Kraja, I. Ntalla, H.R. Warren, X. Guo, K. Schwander, A.K. Manning, M.R. Brown, H. Aschard, M.F. Feitosa, N. Franceschini, Y. Lu, C.Y. Cheng, X. Sim, D. Vojinovic, J. Marten, S.K. Musani, T.O. Kilpelainen, M.A. Richard, S. Aslibekyan, T.M. Bartz, R. Dorajoo, C. Li, Y. Liu, T. Rankinen, A.V. Smith, S.M. Tajuddin, B.O. Tayo, W. Zhao, Y. Zhou, N. Matoba, T. Sofer, M. Alver, M. Amini, M. Boissel, J.F. Chai, X. Chen, J. Divers, I. Gandin, C. Gao, F. Giulianini, A. Goel, S.E. Harris, F.P. Hartwig, M. He, A. Horimoto, F.C. Hsu, A.U. Jackson, C.M. Kammerer, A. Kasturiratne, P. Komulainen, B. Kuhnel, K. Leander, W.J. Lee, K.H. Lin, J. Luan, L.P. Lyytikainen, C.A. McKenzie, C.P. Nelson, R. Noordam, R.A. Scott, W.H.H. Sheu, A. Stancakova, F. Takeuchi, P.J. van der Most, T.V. Varga, R.J. Waken, H. Wang, Y. Wang, E.B. Ware, S. Weiss, W. Wen, L.R. Yanek, W. Zhang, J.H. Zhao, S. Afaq, T. Alfred, N. Amin, D.E. Arking, T. Aung, R.G. Barr, L.F. Bielak, E. Boerwinkle, E.P. Bottinger, P.S. Braund, J.A. Brody, U. Broeckel, B. Cade, A. Campbell, M. Canouil, A. Chakravarti, M. Cocca, F.S. Collins, J.M. Connell, R. de Mutsert, H.J. de Silva, M. Dorr, Q. Duan, C.B. Eaton, G. Ehret, E. Evangelou, J.D. Faul, N.G. Forouhi, O.H. Franco, Y. Friedlander, H. Gao, B. Gigante, C.C. Gu, P. Gupta, S.P. Hagenaars, T.B. Harris, J. He, S. Heikkinen, C.K. Heng, A. Hofman, B.V. Howard, S.C. Hunt, M.R. Irvin, Y. Jia, T. Katsuya, J. Kaufman, N.D. Kerrison, C.C. Khor, W.P. Koh, H.A. Koistinen, C.B. Kooperberg, J.E. Krieger, M. Kubo, Z. Kutalik, J. Kuusisto, T.A. Lakka, C.D. Langefeld, C. Langenberg, L.J. Launer, J.H. Lee, B. Lehne, D. Levy, C.E. Lewis, Y. Li, S. Lifelines Cohort, S.H. Lim, C.T. Liu, J. Liu, J. Liu, Y. Liu, M. Loh, K.K. Lohman, T. Louie, R. Magi, K. Matsuda, T. Meitinger, A. Metspalu, L. Milani, Y. Momozawa, T.H. Mosley, Jr., M.A. Nalls, U. Nasri, J.R. O'Connell, A. Ogunniyi, W.R. Palmas, N.D. Palmer, J.S. Pankow, N.L. Pedersen, A. Peters, P.A. Peyser, O. Polasek, D. Porteous, O.T. Raitakari, F. Renstrom, T.K. Rice, P.M. Ridker, A. Robino, J.G. Robinson, L.M. Rose, I. Rudan, C. Sabanayagam, B.L. Salako, K. Sandow, C.O. Schmidt, P.J. Schreiner, W.R. Scott, P. Sever, M. Sims, C.M. Sitlani, B.H. Smith, J.A. Smith, H. Snieder, J.M. Starr, K. Strauch, H. Tang, K.D. Taylor, Y.Y. Teo, Y.C. Tham, A.G. Uitterlinden, M. Waldenberger, L. Wang, Y.X. Wang, W.B. Wei, G. Wilson, M.K. Wojczynski, Y.B. Xiang, J. Yao, J.M. Yuan, A.B. Zonderman, D.M. Becker, M. Boehnke, D.W. Bowden, J.C. Chambers, Y.I. Chen, D.R. Weir, U. de Faire, I.J. Deary, T. Esko, M. Farrall, T. Forrester, B.I. Freedman, P. Froguel, P. Gasparini, C. Gieger, B.L. Horta, Y.J. Hung, J.B. Jonas, N. Kato, J.S. Kooner, M. Laakso, T. Lehtimaki, K.W. Liang, P.K.E. Magnusson, A.J. Oldehinkel, A.C. Pereira, T. Perls, R. Rauramaa, S. Redline, R. Rettig, N.J. Samani, J. Scott, X.O. Shu, P. van der Harst, L.E. Wagenknecht, N.J. Wareham, H. Watkins, A.R. Wickremasinghe, T. Wu, Y. Kamatani, C.C. Laurie, C. Bouchard, R.S. Cooper, M.K. Evans, V. Gudnason, J. Hixson, S.L.R. Kardia, S.B. Kritchevsky, B.M. Psaty, R.M. van Dam, D.K. Arnett, D.O. Mook-Kanamori, M. Fornage, E.R. Fox, C. Hayward, C.M. van Duijn, E.S. Tai, T.Y. Wong, R.J.F. Loos, A.P. Reiner, C.N. Rotimi, L.J. Bierut, X. Zhu, L.A. Cupples, M.A. Province, J.I. Rotter, P.W. Franks, K. Rice, P. Elliott, M.J. Caulfield, W.J. Gauderman, P.B. Munroe, D.C. Rao, A.C. Morrison, A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure, Hum Mol Genet, (2019).

[164] Y. Lu, S.S. Kweon, C. Tanikawa, W.H. Jia, Y.B. Xiang, Q. Cai, C. Zeng, S.L. Schmit, A. Shin, K. Matsuo, S.H. Jee, D.H. Kim, J. Kim, W. Wen, J. Shi, X. Guo, B. Li, N. Wang, B. Zhang, X. Li, M.H. Shin, H.L. Li, Z. Ren, J.H. Oh, I. Oze, Y.O. Ahn, K.J. Jung, D.V. Conti, F.R. Schumacher, G. Rennert, M.A. Jenkins, P.T. Campbell, M. Hoffmeister, G. Casey, S.B. Gruber, J. Gao, Y.T. Gao, Z.Z. Pan, Y. Kamatani, Y.X. Zeng, X.O. Shu, J. Long, K. Matsuda, W. Zheng, Large-Scale Genome-Wide Association Study of East Asians Identifies Loci Associated With Risk for Colorectal Cancer, Gastroenterology, 156 (2019) 1455-1466.

[163] A.P. Morris, T.H. Le, H. Wu, A. Akbarov, P.J. van der Most, G. Hemani, G.D. Smith, A. Mahajan, K.J. Gaulton, G.N. Nadkarni, A. Valladares-Salgado, N. Wacher-Rodarte, J.C. Mychaleckyj, N.D. Dueker, X. Guo, Y. Hai, J. Haessler, Y. Kamatani, A.M. Stilp, G. Zhu, J.P. Cook, J. Arnlov, S.H. Blanton, M.H. de Borst, E.P. Bottinger, T.A. Buchanan, S. Cechova, F.J. Charchar, P.L. Chu, J. Damman, J. Eales, A.G. Gharavi, V. Giedraitis, A.C. Heath, E. Ipp, K. Kiryluk, H.J. Kramer, M. Kubo, A. Larsson, C.M. Lindgren, Y. Lu, P.A.F. Madden, G.W. Montgomery, G.J. Papanicolaou, L.J. Raffel, R.L. Sacco, E. Sanchez, H. Stark, J. Sundstrom, K.D. Taylor, A.H. Xiang, A. Zivkovic, L. Lind, E. Ingelsson, N.G. Martin, J.B. Whitfield, J. Cai, C.C. Laurie, Y. Okada, K. Matsuda, C. Kooperberg, Y.I. Chen, T. Rundek, S.S. Rich, R.J.F. Loos, E.J. Parra, M. Cruz, J.I. Rotter, H. Snieder, M. Tomaszewski, B.D. Humphreys, N. Franceschini, Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies, Nature communications, 10 (2019) 29.

[162] M. Nakatochi, M. Kanai, A. Nakayama, A. Hishida, Y. Kawamura, S. Ichihara, M. Akiyama, H. Ikezaki, N. Furusyo, S. Shimizu, K. Yamamoto, M. Hirata, R. Okada, S. Kawai, M. Kawaguchi, Y. Nishida, C. Shimanoe, R. Ibusuki, T. Takezaki, M. Nakajima, M. Takao, E. Ozaki, D. Matsui, T. Nishiyama, S. Suzuki, N. Takashima, Y. Kita, K. Endoh, K. Kuriki, H. Uemura, K. Arisawa, I. Oze, K. Matsuo, Y. Nakamura, H. Mikami, T. Tamura, H. Nakashima, T. Nakamura, N. Kato, K. Matsuda, Y. Murakami, T. Matsubara, M. Naito, M. Kubo, Y. Kamatani, N. Shinomiya, M. Yokota, K. Wakai, Y. Okada, H. Matsuo, Genome-wide meta-analysis identifies multiple novel loci associated with serum uric acid levels in Japanese individuals, Commun Biol, 2 (2019) 115.

[161] S. Okazaki, T. Morimoto, Y. Kamatani, T. Kamimura, H. Kobayashi, K. Harada, T. Tomita, A. Higashiyama, J.C. Takahashi, J. Nakagawara, M. Koga, K. Toyoda, K. Washida, S. Saito, A. Takahashi, M. Hirata, K. Matsuda, H. Mochizuki, M. Chong, G. Pare, M. O'Donnell, T. Ago, J. Hata, T. Ninomiya, M. Dichgans, S. Debette, M. Kubo, A. Koizumi, M. Ihara, Moyamoya Disease Susceptibility Variant RNF213 p.R4810K Increases the Risk of Ischemic Stroke Attributable to Large-Artery Atherosclerosis, Circulation, 139 (2019) 295-298.

[160] K. Suzuki, M. Akiyama, K. Ishigaki, M. Kanai, J. Hosoe, N. Shojima, A. Hozawa, A. Kadota, K. Kuriki, M. Naito, K. Tanno, Y. Ishigaki, M. Hirata, K. Matsuda, N. Iwata, M. Ikeda, N. Sawada, T. Yamaji, M. Iwasaki, S. Ikegawa, S. Maeda, Y. Murakami, K. Wakai, S. Tsugane, M. Sasaki, M. Yamamoto, Y. Okada, M. Kubo, Y. Kamatani, M. Horikoshi, T. Yamauchi, T. Kadowaki, Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population, Nat Genet, 51 (2019) 379-386.

[159] C. Tanikawa, Y. Kamatani, C. Terao, M. Usami, A. Takahashi, Y. Momozawa, K. Suzuki, S. Ogishima, A. Shimizu, M. Satoh, K. Matsuo, H. Mikami, M. Naito, K. Wakai, T. Yamaji, N. Sawada, M. Iwasaki, S. Tsugane, K. Kohri, A.S.L. Yu, T. Yasui, Y. Murakami, M. Kubo, K. Matsuda, Novel Risk Loci Identified in a Genome-Wide Association Study of Urolithiasis in a Japanese Population, J Am Soc Nephrol, 30 (2019) 855-864.

[158] T. Motegi, Y. Kochi, K. Matsuda, M. Kubo, K. Yamamoto, Y. Momozawa, Identification of rare coding variants in TYK2 protective for rheumatoid arthritis in the Japanese population and their effects on cytokine signalling, Ann Rheum Dis, 78 (2019) 1062-1069.

[157] Y. Tsuda, M. Hirata, K. Katayama, T. Motoi, D. Matsubara, Y. Oda, M. Fujita, H. Kobayashi, H. Kawano, Y. Nishida, T. Sakai, T. Okuma, T. Goto, K. Ogura, A. Kawai, K. Ae, U. Anazawa, Y. Suehara, S. Iwata, S. Miyano, S. Imoto, T. Shibata, H. Nakagawa, R. Yamaguchi, S. Tanaka, K. Matsuda, Massively parallel sequencing of tenosynovial giant cell tumors reveals novel CSF1 fusion transcripts and novel somatic CBL mutations, International journal of cancer. Journal international du cancer, (2019).

[156] Y.Y. Liu, C. Tanikawa, K. Ueda, K. Matsuda, INKA2, a novel p53 target that interacts with the serine/threonine kinase PAK4, Int J Oncol, 54 (2019) 1907-1920.

[155] S.C. Larsson, M. Traylor, S. Burgess, G.B. Boncoraglio, C. Jern, K. Michaelsson, H.S. Markus, M.p.o.t.I.S.G. Consortium, Serum magnesium and calcium levels in relation to ischemic stroke: Mendelian randomization study, Neurology, 92 (2019) e944-e950.

[154] J. Hirata, K. Hosomichi, S. Sakaue, M. Kanai, H. Nakaoka, K. Ishigaki, K. Suzuki, M. Akiyama, T. Kishikawa, K. Ogawa, T. Masuda, K. Yamamoto, M. Hirata, K. Matsuda, Y. Momozawa, I. Inoue, M. Kubo, Y. Kamatani, Y. Okada, Genetic and phenotypic landscape of the major histocompatibilty complex region in the Japanese population, Nat Genet, (2019).

[153] M. Saito, K. Okumura, E. Isogai, K. Araki, C. Tanikawa, K. Matsuda, T. Kamijo, R. Kominami, Y. Wakabayashi, A Polymorphic Variant in p19(Arf) Confers Resistance to Chemically Induced Skin Tumors by Activating the p53 Pathway, J Invest Dermatol, 139 (2019) 1459-1469.

[152] M. Sekimizu, A. Yoshida, S. Mitani, N. Asano, M. Hirata, T. Kubo, F. Yamazaki, H. Sakamoto, M. Kato, N. Makise, T. Mori, N. Yamazaki, S. Sekine, I. Oda, S.I. Watanabe, H. Hiraga, T. Yonemoto, T. Kawamoto, N. Naka, Y. Funauchi, Y. Nishida, K. Honoki, H. Kawano, H. Tsuchiya, T. Kunisada, K. Matsuda, K. Inagaki, A. Kawai, H. Ichikawa, Frequent mutations of genes encoding vacuolar H(+) -ATPase components in granular cell tumors, Genes, chromosomes & cancer, 58 (2019) 373-380.

[151] N. Matoba, M. Akiyama, K. Ishigaki, M. Kanai, A. Takahashi, Y. Momozawa, S. Ikegawa, M. Ikeda, N. Iwata, M. Hirata, K. Matsuda, M. Kubo, Y. Okada, Y. Kamatani, GWAS of smoking behaviour in 165,436 Japanese people reveals seven new loci and shared genetic architecture, Nat Hum Behav, 3 (2019) 471-477.

 

2018

[150] A. Teumer, L. Chaker, S. Groeneweg, Y. Li, C. Di Munno, C. Barbieri, U.T. Schultheiss, M. Traglia, T.S. Ahluwalia, M. Akiyama, E.V.R. Appel, D.E. Arking, A. Arnold, A. Astrup, M. Beekman, J.P. Beilby, S. Bekaert, E. Boerwinkle, S.J. Brown, M. De Buyzere, P.J. Campbell, G. Ceresini, C. Cerqueira, F. Cucca, I.J. Deary, J. Deelen, K.U. Eckardt, A.B. Ekici, J.G. Eriksson, L. Ferrrucci, T. Fiers, E. Fiorillo, I. Ford, C.S. Fox, C. Fuchsberger, T.E. Galesloot, C. Gieger, M. Gogele, A. De Grandi, N. Grarup, K.H. Greiser, K. Haljas, T. Hansen, S.E. Harris, D. van Heemst, M. den Heijer, A.A. Hicks, W. den Hollander, G. Homuth, J. Hui, M.A. Ikram, T. Ittermann, R.A. Jensen, J. Jing, J.W. Jukema, E. Kajantie, Y. Kamatani, E. Kasbohm, J.M. Kaufman, L.A. Kiemeney, M. Kloppenburg, F. Kronenberg, M. Kubo, J. Lahti, B. Lapauw, S. Li, D.C.M. Liewald, S. Lifelines Cohort, E.M. Lim, A. Linneberg, M. Marina, D. Mascalzoni, K. Matsuda, D. Medenwald, C. Meisinger, I. Meulenbelt, T. De Meyer, H.E. Meyer Zu Schwabedissen, R. Mikolajczyk, M. Moed, R.T. Netea-Maier, I.M. Nolte, Y. Okada, M. Pala, C. Pattaro, O. Pedersen, A. Petersmann, E. Porcu, I. Postmus, P.P. Pramstaller, B.M. Psaty, Y.F.M. Ramos, R. Rawal, P. Redmond, J.B. Richards, E.R. Rietzschel, F. Rivadeneira, G. Roef, J.I. Rotter, C.F. Sala, D. Schlessinger, E. Selvin, P.E. Slagboom, N. Soranzo, T.I.A. Sorensen, T.D. Spector, J.M. Starr, D.J. Stott, Y. Taes, D. Taliun, T. Tanaka, B. Thuesen, D. Tiller, D. Toniolo, A.G. Uitterlinden, W.E. Visser, J.P. Walsh, S.G. Wilson, B.H.R. Wolffenbuttel, Q. Yang, H.F. Zheng, A. Cappola, R.P. Peeters, S. Naitza, H. Volzke, S. Sanna, A. Kottgen, T.J. Visser, M. Medici, Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation, Nature communications, 9 (2018) 4455.

[149] V. Yodsurang, Y. Tang, Y. Takahashi, C. Tanikawa, Y. Kamatani, A. Takahashi, Y. Momozawa, N. Fuse, J. Sugawara, A. Shimizu, A. Fukushima, A. Hishida, N. Furusyo, M. Naito, K. Wakai, T. Yamaji, N. Sawada, M. Iwasaki, S. Tsugane, M. Hirata, Y. Murakami, M. Kubo, K. Matsuda, Genome-wide association study (GWAS) of ovarian cancer in Japanese predicted regulatory variants in 22q13.1, PloS one, 13 (2018) e0209096.

[148] F. Takeuchi, M. Akiyama, N. Matoba, T. Katsuya, M. Nakatochi, Y. Tabara, A. Narita, W.Y. Saw, S. Moon, C.N. Spracklen, J.F. Chai, Y.J. Kim, L. Zhang, C. Wang, H. Li, H. Li, J.Y. Wu, R. Dorajoo, J.L. Nierenberg, Y.X. Wang, J. He, D.A. Bennett, A. Takahashi, Y. Momozawa, M. Hirata, K. Matsuda, H. Rakugi, E. Nakashima, M. Isono, M. Shirota, A. Hozawa, S. Ichihara, T. Matsubara, K. Yamamoto, K. Kohara, M. Igase, S. Han, P. Gordon-Larsen, W. Huang, N.R. Lee, L.S. Adair, M.Y. Hwang, J. Lee, M.L. Chee, C. Sabanayagam, W. Zhao, J. Liu, D.F. Reilly, L. Sun, S. Huo, T.L. Edwards, J. Long, L.C. Chang, C.H. Chen, J.M. Yuan, W.P. Koh, Y. Friedlander, T.N. Kelly, W. Bin Wei, L. Xu, H. Cai, Y.B. Xiang, K. Lin, R. Clarke, R.G. Walters, I.Y. Millwood, L. Li, J.C. Chambers, J.S. Kooner, P. Elliott, P. van der Harst, C. International Genomics of Blood Pressure, Z. Chen, M. Sasaki, X.O. Shu, J.B. Jonas, J. He, C.K. Heng, Y.T. Chen, W. Zheng, X. Lin, Y.Y. Teo, E.S. Tai, C.Y. Cheng, T.Y. Wong, X. Sim, K.L. Mohlke, M. Yamamoto, B.J. Kim, T. Miki, T. Nabika, M. Yokota, Y. Kamatani, M. Kubo, N. Kato, Interethnic analyses of blood pressure loci in populations of East Asian and European descent, Nature communications, 9 (2018) 5052.

[147] C. Tanikawa, Y. Kamatani, O. Toyoshima, H. Sakamoto, H. Ito, A. Takahashi, Y. Momozawa, M. Hirata, N. Fuse, T. Takai-Igarashi, A. Shimizu, M. Sasaki, T. Yamaji, N. Sawada, M. Iwasaki, S. Tsugane, M. Naito, A. Hishida, K. Wakai, N. Furusyo, Y. Murakami, Y. Nakamura, I. Imoto, J. Inazawa, I. Oze, N. Sato, F. Tanioka, H. Sugimura, H. Hirose, T. Yoshida, K. Matsuo, K. Michiaki, K. Matsuda, A GWAS identifies gastric cancer susceptibility loci at 12q24.11-12 and 20q11.21, Cancer Sci, (2018).

[146] Y. Momozawa, Y. Iwasaki, M.T. Parsons, Y. Kamatani, A. Takahashi, C. Tamura, T. Katagiri, T. Yoshida, S. Nakamura, K. Sugano, Y. Miki, M. Hirata, K. Matsuda, A.B. Spurdle, M. Kubo, Germline pathogenic variants of 11 breast cancer genes in 7,051 Japanese patients and 11,241 controls, Nature communications, 9 (2018) 4083.

[145] Y. Kojima, T. Koguchi, K. Mizuno, Y. Sato, S. Hoshi, J. Hata, H. Nishio, D. Hashimoto, S. Matsushita, K. Suzuki, S. Miyagawa, C.C. Hui, C. Tanikawa, Y. Murakami, G. Yamada, Y. Hayashi, K. Matsuda, Single nucleotide polymorphisms of HAAO and IRX 6 genes as risk factors for hypospadias, J Urol, (2018).

[144] K. Ohki, N. Kiyokawa, Y. Saito, S. Hirabayashi, K. Nakabayashi, H. Ichikawa, Y. Momozawa, K. Okamura, A. Yoshimi, H. Ogata-Kawata, H. Sakamoto, M. Kato, K. Fukushima, D. Hasegawa, H. Fukushima, M. Imai, R. Kajiwara, T. Koike, I. Komori, A. Matsui, M. Mori, K. Moriwaki, Y. Noguchi, M.J. Park, T. Ueda, S. Yamamoto, K. Matsuda, T. Yoshida, K. Matsumoto, K. Hata, M. Kubo, Y. Matsubara, H. Takahashi, T. Fukushima, Y. Hayashi, K. Koh, A. Manabe, A. Ohara, Clinical and molecular characteristics of MEF2D fusion-positive precursor B-cell acute lymphoblastic leukemia in childhood, including a novel translocation resulting in MEF2D-HNRNPH1 gene fusion, Haematologica, (2018).

[143] M. Miyazaki, R. Otomo, Y. Matsushima-Hibiya, H. Suzuki, A. Nakajima, N. Abe, A. Tomiyama, K. Ichimura, K. Matsuda, T. Watanabe, T. Ochiya, H. Nakagama, R. Sakai, M. Enari, The p53 activator overcomes resistance to ALK inhibitors by regulating p53-target selectivity in ALK-driven neuroblastomas, Cell Death Discov, 4 (2018) 56.

[142] M. Horikoshi, F.R. Day, M. Akiyama, M. Hirata, Y. Kamatani, K. Matsuda, K. Ishigaki, M. Kanai, H. Wright, C.A. Toro, S.R. Ojeda, A. Lomniczi, M. Kubo, K.K. Ong, J.R.B. Perry, Elucidating the genetic architecture of reproductive ageing in the Japanese population, Nature communications, 9 (2018) 1977.

[141] S.L. Schmit, C.K. Edlund, F.R. Schumacher, J. Gong, T.A. Harrison, J.R. Huyghe, C. Qu, M. Melas, D.J. Van Den Berg, H. Wang, S. Tring, S.J. Plummer, D. Albanes, M.H. Alonso, C.I. Amos, K. Anton, A.K. Aragaki, V. Arndt, E.L. Barry, S.I. Berndt, S. Bezieau, S. Bien, A. Bloomer, J. Boehm, M.C. Boutron-Ruault, H. Brenner, S. Brezina, D.D. Buchanan, K. Butterbach, B.J. Caan, P.T. Campbell, C.S. Carlson, J.E. Castelao, A.T. Chan, J. Chang-Claude, S.J. Chanock, I. Cheng, Y.W. Cheng, L.S. Chin, J.M. Church, T. Church, G.A. Coetzee, M. Cotterchio, M. Cruz Correa, K.R. Curtis, D. Duggan, D.F. Easton, D. English, E.J.M. Feskens, R. Fischer, L.M. FitzGerald, B.K. Fortini, L.G. Fritsche, C.S. Fuchs, M. Gago-Dominguez, M. Gala, S.J. Gallinger, W.J. Gauderman, G.G. Giles, E.L. Giovannucci, S.M. Gogarten, C. Gonzalez-Villalpando, E.M. Gonzalez-Villalpando, W.M. Grady, J.K. Greenson, A. Gsur, M. Gunter, C.A. Haiman, J. Hampe, S. Harlid, J.F. Harju, R.B. Hayes, P. Hofer, M. Hoffmeister, J.L. Hopper, S.C. Huang, J.M. Huerta, T.J. Hudson, D.J. Hunter, G.E. Idos, M. Iwasaki, R.D. Jackson, E.J. Jacobs, S.H. Jee, M.A. Jenkins, W.H. Jia, S. Jiao, A.D. Joshi, L.N. Kolonel, S. Kono, C. Kooperberg, V. Krogh, T. Kuehn, S. Kury, A. LaCroix, C.A. Laurie, F. Lejbkowicz, M. Lemire, H.J. Lenz, D. Levine, C.I. Li, L. Li, W. Lieb, Y. Lin, N.M. Lindor, Y.R. Liu, F. Loupakis, Y. Lu, F. Luh, J. Ma, C. Mancao, F.J. Manion, S.D. Markowitz, V. Martin, K. Matsuda, K. Matsuo, K.J. McDonnell, C.E. McNeil, R. Milne, A.J. Molina, B. Mukherjee, N. Murphy, P.A. Newcomb, K. Offit, H. Omichessan, D. Palli, J.P.P. Cotore, J. Perez-Mayoral, P.D. Pharoah, J.D. Potter, C. Qu, L. Raskin, G. Rennert, H.S. Rennert, B.M. Riggs, C. Schafmayer, R.E. Schoen, T.A. Sellers, D. Seminara, G. Severi, W. Shi, D. Shibata, X.O. Shu, E.M. Siegel, M.L. Slattery, M. Southey, Z.K. Stadler, M.C. Stern, S. Stintzing, D. Taverna, S.N. Thibodeau, D.C. Thomas, A. Trichopoulou, S. Tsugane, C.M. Ulrich, F.J.B. van Duijnhoven, B. van Guelpan, J. Vijai, J. Virtamo, S.J. Weinstein, E. White, A.K. Win, A. Wolk, M. Woods, A.H. Wu, K. Wu, Y.B. Xiang, Y. Yen, B.W. Zanke, Y.X. Zeng, B. Zhang, N. Zubair, S.S. Kweon, J.C. Figueiredo, W. Zheng, L.L. Marchand, A. Lindblom, V. Moreno, U. Peters, G. Casey, L. Hsu, D.V. Conti, S.B. Gruber, Novel Common Genetic Susceptibility Loci for Colorectal Cancer, J Natl Cancer Inst, (2018).

[140] R. Malik, G. Chauhan, M. Traylor, M. Sargurupremraj, Y. Okada, A. Mishra, L. Rutten-Jacobs, A.K. Giese, S.W. van der Laan, S. Gretarsdottir, C.D. Anderson, M. Chong, H.H.H. Adams, T. Ago, P. Almgren, P. Amouyel, H. Ay, T.M. Bartz, O.R. Benavente, S. Bevan, G.B. Boncoraglio, R.D. Brown, Jr., A.S. Butterworth, C. Carrera, C.L. Carty, D.I. Chasman, W.M. Chen, J.W. Cole, A. Correa, I. Cotlarciuc, C. Cruchaga, J. Danesh, P.I.W. de Bakker, A.L. DeStefano, M. den Hoed, Q. Duan, S.T. Engelter, G.J. Falcone, R.F. Gottesman, R.P. Grewal, V. Gudnason, S. Gustafsson, J. Haessler, T.B. Harris, A. Hassan, A.S. Havulinna, S.R. Heckbert, E.G. Holliday, G. Howard, F.C. Hsu, H.I. Hyacinth, M.A. Ikram, E. Ingelsson, M.R. Irvin, X. Jian, J. Jimenez-Conde, J.A. Johnson, J.W. Jukema, M. Kanai, K.L. Keene, B.M. Kissela, D.O. Kleindorfer, C. Kooperberg, M. Kubo, L.A. Lange, C.D. Langefeld, C. Langenberg, L.J. Launer, J.M. Lee, R. Lemmens, D. Leys, C.M. Lewis, W.Y. Lin, A.G. Lindgren, E. Lorentzen, P.K. Magnusson, J. Maguire, A. Manichaikul, P.F. McArdle, J.F. Meschia, B.D. Mitchell, T.H. Mosley, M.A. Nalls, T. Ninomiya, M.J. O'Donnell, B.M. Psaty, S.L. Pulit, K. Rannikmae, A.P. Reiner, K.M. Rexrode, K. Rice, S.S. Rich, P.M. Ridker, N.S. Rost, P.M. Rothwell, J.I. Rotter, T. Rundek, R.L. Sacco, S. Sakaue, M.M. Sale, V. Salomaa, B.R. Sapkota, R. Schmidt, C.O. Schmidt, U. Schminke, P. Sharma, A. Slowik, C.L.M. Sudlow, C. Tanislav, T. Tatlisumak, K.D. Taylor, V.N.S. Thijs, G. Thorleifsson, U. Thorsteinsdottir, S. Tiedt, S. Trompet, C. Tzourio, C.M. van Duijn, M. Walters, N.J. Wareham, S. Wassertheil-Smoller, J.G. Wilson, K.L. Wiggins, Q. Yang, S. Yusuf, J.C. Bis, T. Pastinen, A. Ruusalepp, E.E. Schadt, S. Koplev, J.L.M. Bjorkegren, V. Codoni, M. Civelek, N.L. Smith, D.A. Tregouet, I.E. Christophersen, C. Roselli, S.A. Lubitz, P.T. Ellinor, E.S. Tai, J.S. Kooner, N. Kato, J. He, P. van der Harst, P. Elliott, J.C. Chambers, F. Takeuchi, A.D. Johnson, D.K. Sanghera, O. Melander, C. Jern, D. Strbian, I. Fernandez-Cadenas, W.T. Longstreth, Jr., A. Rolfs, J. Hata, D. Woo, J. Rosand, G. Pare, J.C. Hopewell, D. Saleheen, K. Stefansson, B.B. Worrall, S.J. Kittner, S. Seshadri, M. Fornage, H.S. Markus, J.M.M. Howson, Y. Kamatani, S. Debette, M. Dichgans, R. Malik, G. Chauhan, M. Traylor, M. Sargurupremraj, Y. Okada, A. Mishra, L. Rutten-Jacobs, A.K. Giese, S.W. van der Laan, S. Gretarsdottir, C.D. Anderson, M. Chong, H.H.H. Adams, T. Ago, P. Almgren, P. Amouyel, H. Ay, T.M. Bartz, O.R. Benavente, S. Bevan, G.B. Boncoraglio, R.D. Brown, Jr., A.S. Butterworth, C. Carrera, C.L. Carty, D.I. Chasman, W.M. Chen, J.W. Cole, A. Correa, I. Cotlarciuc, C. Cruchaga, J. Danesh, P.I.W. de Bakker, A.L. DeStefano, M.D. Hoed, Q. Duan, S.T. Engelter, G.J. Falcone, R.F. Gottesman, R.P. Grewal, V. Gudnason, S. Gustafsson, J. Haessler, T.B. Harris, A. Hassan, A.S. Havulinna, S.R. Heckbert, E.G. Holliday, G. Howard, F.C. Hsu, H.I. Hyacinth, M.A. Ikram, E. Ingelsson, M.R. Irvin, X. Jian, J. Jimenez-Conde, J.A. Johnson, J.W. Jukema, M. Kanai, K.L. Keene, B.M. Kissela, D.O. Kleindorfer, C. Kooperberg, M. Kubo, L.A. Lange, C.D. Langefeld, C. Langenberg, L.J. Launer, J.M. Lee, R. Lemmens, D. Leys, C.M. Lewis, W.Y. Lin, A.G. Lindgren, E. Lorentzen, P.K. Magnusson, J. Maguire, A. Manichaikul, P.F. McArdle, J.F. Meschia, B.D. Mitchell, T.H. Mosley, M.A. Nalls, T. Ninomiya, M.J. O'Donnell, B.M. Psaty, S.L. Pulit, K. Rannikmae, A.P. Reiner, K.M. Rexrode, K. Rice, S.S. Rich, P.M. Ridker, N.S. Rost, P.M. Rothwell, J.I. Rotter, T. Rundek, R.L. Sacco, S. Sakaue, M.M. Sale, V. Salomaa, B.R. Sapkota, R. Schmidt, C.O. Schmidt, U. Schminke, P. Sharma, A. Slowik, C.L.M. Sudlow, C. Tanislav, T. Tatlisumak, K.D. Taylor, V.N.S. Thijs, G. Thorleifsson, U. Thorsteinsdottir, S. Tiedt, S. Trompet, C. Tzourio, C.M. van Duijn, M. Walters, N.J. Wareham, S. Wassertheil-Smoller, J.G. Wilson, K.L. Wiggins, Q. Yang, S. Yusuf, N. Amin, H.S. Aparicio, D.K. Arnett, J. Attia, A.S. Beiser, C. Berr, J.E. Buring, M. Bustamante, V. Caso, Y.C. Cheng, S.H. Choi, A. Chowhan, N. Cullell, J.F. Dartigues, H. Delavaran, P. Delgado, M. Dorr, G. Engstrom, I. Ford, W.S. Gurpreet, A. Hamsten, L. Heitsch, A. Hozawa, L. Ibanez, A. Ilinca, M. Ingelsson, M. Iwasaki, R.D. Jackson, K. Jood, P. Jousilahti, S. Kaffashian, L. Kalra, M. Kamouchi, T. Kitazono, O. Kjartansson, M. Kloss, P.J. Koudstaal, J. Krupinski, D.L. Labovitz, C.C. Laurie, C.R. Levi, L. Li, L. Lind, C.M. Lindgren, V. Lioutas, Y.M. Liu, O.L. Lopez, H. Makoto, N. Martinez-Majander, K. Matsuda, N. Minegishi, J. Montaner, A.P. Morris, E. Muino, M. Muller-Nurasyid, B. Norrving, S. Ogishima, E.A. Parati, L.R. Peddareddygari, N.L. Pedersen, J. Pera, M. Perola, A. Pezzini, S. Pileggi, R. Rabionet, I. Riba-Llena, M. Ribases, J.R. Romero, J. Roquer, A.G. Rudd, A.P. Sarin, R. Sarju, C. Sarnowski, M. Sasaki, C.L. Satizabal, M. Satoh, N. Sattar, N. Sawada, G. Sibolt, A. Sigurdsson, A. Smith, K. Sobue, C. Soriano-Tarraga, T. Stanne, O.C. Stine, D.J. Stott, K. Strauch, T. Takai, H. Tanaka, K. Tanno, A. Teumer, L. Tomppo, N.P. Torres-Aguila, E. Touze, S. Tsugane, A.G. Uitterlinden, E.M. Valdimarsson, S.J. van der Lee, H. Volzke, K. Wakai, D. Weir, S.R. Williams, C.D.A. Wolfe, Q. Wong, H. Xu, T. Yamaji, D.K. Sanghera, O. Melander, C. Jern, D. Strbian, I. Fernandez-Cadenas, W.T. Longstreth, Jr., A. Rolfs, J. Hata, D. Woo, J. Rosand, G. Pare, J.C. Hopewell, D. Saleheen, K. Stefansson, B.B. Worrall, S.J. Kittner, S. Seshadri, M. Fornage, H.S. Markus, J.M.M. Howson, Y. Kamatani, S. Debette, M. Dichgans, A.F. Consortium, H. Cohorts for, C. Aging Research in Genomic Epidemiology, C. International Genomics of Blood Pressure, I. Consortium, Starnet, G. BioBank Japan Cooperative Hospital, C. Consortium, E.-C. Consortium, E.P.-I. Consortium, C. International Stroke Genetics, M. Consortium, C.C. Neurology Working Group of the, N.S.G. Network, U.K.Y.L.D. Study, M. Consortium, M. Consortium, Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes, Nat Genet, 50 (2018) 524-537.

[139] Y. Okada, Y. Momozawa, S. Sakaue, M. Kanai, K. Ishigaki, M. Akiyama, T. Kishikawa, Y. Arai, T. Sasaki, K. Kosaki, M. Suematsu, K. Matsuda, K. Yamamoto, M. Kubo, N. Hirose, Y. Kamatani, Deep whole-genome sequencing reveals recent selection signatures linked to evolution and disease risk of Japanese, Nature communications, 9 (2018) 1631.

[138] Y. Shiga, M. Akiyama, K.M. Nishiguchi, K. Sato, N. Shimozawa, A. Takahashi, Y. Momozawa, M. Hirata, K. Matsuda, T. Yamaji, M. Iwasaki, S. Tsugane, I. Oze, H. Mikami, M. Naito, K. Wakai, M. Yoshikawa, M. Miyake, K. Yamashiro, G. Japan Glaucoma Society Omics, K. Kashiwagi, T. Iwata, F. Mabuchi, M. Takamoto, M. Ozaki, K. Kawase, M. Aihara, M. Araie, T. Yamamoto, Y. Kiuchi, M. Nakamura, Y. Ikeda, K.H. Sonoda, T. Ishibashi, K. Nitta, A. Iwase, S. Shirato, Y. Oka, M. Satoh, M. Sasaki, N. Fuse, Y. Suzuki, C.Y. Cheng, C.C. Khor, M. Baskaran, S. Perera, T. Aung, E.N. Vithana, J.N. Cooke Bailey, J.H. Kang, L.R. Pasquale, J.L. Haines, N. Consortium, J.L. Wiggs, K.P. Burdon, P. Gharahkhani, A.W. Hewitt, D.A. Mackey, S. MacGregor, J.E. Craig, R.R. Allingham, M. Hauser, A. Ashaye, D.L. Budenz, S. Akafo, S.E.I. Williams, Y. Kamatani, T. Nakazawa, M. Kubo, Genome-wide association study identifies seven novel susceptibility loci for primary open-angle glaucoma, Hum Mol Genet, 27 (2018) 1486-1496.

[137] C. Tanikawa, Y. Kamatani, A. Takahashi, Y. Momozawa, K. Leveque, S. Nagayama, K. Mimori, M. Mori, H. Ishii, J. Inazawa, J. Yasuda, A. Tsuboi, A. Shimizu, M. Sasaki, T. Yamaji, N. Sawada, M. Iwasaki, S. Tsugane, M. Naito, K. Wakai, T. Koyama, T. Takezaki, K. Yuji, Y. Murakami, Y. Nakamura, M. Kubo, K. Matsuda, GWAS Identifies Two Novel Colorectal Cancer Loci at 16q24.1 and 20q13.12, Carcinogenesis, (2018).

[136] C. Tanikawa, K. Ueda, A. Suzuki, A. Iida, R. Nakamura, N. Atsuta, G. Tohnai, G. Sobue, N. Saichi, Y. Momozawa, Y. Kamatani, M. Kubo, K. Yamamoto, Y. Nakamura, K. Matsuda, Citrullination of RGG Motifs in FET Proteins by PAD4 Regulates Protein Aggregation and ALS Susceptibility, Cell Rep, 22 (2018) 1473-1483.

[135] M. Kanai, M. Akiyama, A. Takahashi, N. Matoba, Y. Momozawa, M. Ikeda, N. Iwata, S. Ikegawa, M. Hirata, K. Matsuda, M. Kubo, Y. Okada, Y. Kamatani, Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases, Nat Genet, (2018).

[134] O. Toyoshima, C. Tanikawa, R. Yamamoto, H. Watanabe, H. Yamashita, K. Sakitani, S. Yoshida, M. Kubo, K. Matsuo, H. Ito, K. Koike, Y. Seto, K. Matsuda, Decrease in PSCA expression caused by Helicobacter pylori infection may promote progression to severe gastritis, Oncotarget, 9 (2018) 3936-3945.

[133] M. Miyazaki, R. Otomo, Y. Matsushima-Hibiya, H. Suzuki, A. Nakajima, N. Abe, A. Tomiyama, K. Ichimura, K. Matsuda, T. Watanabe, T. Ochiya, H. Nakagama, R. Sakai, M. Enari, The p53 activator overcomes resistance to ALK inhibitors by regulating p53-target selectivity in ALK-driven neuroblastomas, Cell Death Discov, 4 (2018) 56.

 

2017 

 

[132] T. Miyamoto, P.H.Y. Lo, N. Saichi, K. Ueda, M. Hirata, C. Tanikawa, K. Matsuda, Argininosuccinate synthase 1 is an intrinsic Akt repressor transactivated by p53, Sci Adv, 3 (2017) e1603204.

[131] V. Yodsurang, C. Tanikawa, T. Miyamoto, P.H.Y. Lo, M. Hirata, K. Matsuda, Identification of a novel p53 target, COL17A1, that inhibits breast cancer cell migration and invasion, Oncotarget, 8 (2017) 55790-55803.

[130] Y. Tsuda, C. Tanikawa, T. Miyamoto, M. Hirata, V. Yodsurang, Y.Z. Zhang, S. Imoto, R. Yamaguchi, S. Miyano, H. Takayanagi, H. Kawano, H. Nakagawa, S. Tanaka, K. Matsuda, Identification of a p53 target, CD137L, that mediates growth suppression and immune response of osteosarcoma cells, Scientific reports, 7 (2017) 10739.

[129] M. Akiyama, Y. Okada, M. Kanai, A. Takahashi, Y. Momozawa, M. Ikeda, N. Iwata, S. Ikegawa, M. Hirata, K. Matsuda, M. Iwasaki, T. Yamaji, N. Sawada, T. Hachiya, K. Tanno, A. Shimizu, A. Hozawa, N. Minegishi, S. Tsugane, M. Yamamoto, M. Kubo, Y. Kamatani, Genome-wide association study identifies 112 new loci for body mass index in the Japanese population, Nat Genet, 49 (2017) 1458-1467.

[128] T. Miyamoto, C. Tanikawa, V. Yodsurang, Y.Z. Zhang, S. Imoto, R. Yamaguchi, S. Miyano, H. Nakagawa, K. Matsuda, Identification of a p53-repressed gene module in breast cancer cells, Oncotarget, 8 (2017) 55821-55836.

[127] C. Tanikawa, Y.Z. Zhang, R. Yamamoto, Y. Tsuda, M. Tanaka, Y. Funauchi, J. Mori, S. Imoto, R. Yamaguchi, Y. Nakamura, S. Miyano, H. Nakagawa, K. Matsuda, The Transcriptional Landscape of p53 Signalling Pathway, EBioMedicine, 20 (2017) 109-119.

[126] Y. Sapkota, V. Steinthorsdottir, A.P. Morris, A. Fassbender, N. Rahmioglu, I. De Vivo, J.E. Buring, F. Zhang, T.L. Edwards, S. Jones, D. O, D. Peterse, K.M. Rexrode, P.M. Ridker, A.J. Schork, S. MacGregor, N.G. Martin, C.M. Becker, S. Adachi, K. Yoshihara, T. Enomoto, A. Takahashi, Y. Kamatani, K. Matsuda, M. Kubo, G. Thorleifsson, R.T. Geirsson, U. Thorsteinsdottir, L.M. Wallace, P.-S.S.I.B.G. i, J. Yang, D.R. Velez Edwards, M. Nyegaard, S.K. Low, K.T. Zondervan, S.A. Missmer, T. D'Hooghe, G.W. Montgomery, D.I. Chasman, K. Stefansson, J.Y. Tung, D.R. Nyholt, Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism, Nature communications, 8 (2017) 15539.

[125] Y. Takahashi, C. Tanikawa, T. Miyamoto, M. Hirata, G. Wang, K. Ueda, T. Komatsu, K. Matsuda, Regulation of tubular recycling endosome biogenesis by the p53-MICALL1 pathway, Int J Oncol, 51 (2017) 724-736.

[124] J. Lin, S. Chung, K. Ueda, K. Matsuda, Y. Nakamura, J.H. Park, GALNT6 Stabilizes GRP78 Protein by O-glycosylation and Enhances its Activity to Suppress Apoptosis Under Stress Condition, Neoplasia, 19 (2017) 43-53.

[123] F.J. van Rooij, R. Qayyum, A.V. Smith, Y. Zhou, S. Trompet, T. Tanaka, M.F. Keller, L.C. Chang, H. Schmidt, M.L. Yang, M.H. Chen, J. Hayes, A.D. Johnson, L.R. Yanek, C. Mueller, L. Lange, J.S. Floyd, M. Ghanbari, A.B. Zonderman, J.W. Jukema, A. Hofman, C.M. van Duijn, K.C. Desch, Y. Saba, A.B. Ozel, B.M. Snively, J.Y. Wu, R. Schmidt, M. Fornage, R.J. Klein, C.S. Fox, K. Matsuda, N. Kamatani, P.S. Wild, D.J. Stott, I. Ford, P.E. Slagboom, J. Yang, A.Y. Chu, A.J. Lambert, A.G. Uitterlinden, O.H. Franco, E. Hofer, D. Ginsburg, B. Hu, B. Keating, U.M. Schick, J.A. Brody, J.Z. Li, Z. Chen, T. Zeller, J.M. Guralnik, D.I. Chasman, L.L. Peters, M. Kubo, D.M. Becker, J. Li, G. Eiriksdottir, J.I. Rotter, D. Levy, V. Grossmann, K.V. Patel, C.H. Chen, P. BioBank Japan, P.M. Ridker, H. Tang, L.J. Launer, K.M. Rice, R. Li-Gao, L. Ferrucci, M.K. Evans, A. Choudhuri, E. Trompouki, B.J. Abraham, S. Yang, A. Takahashi, Y. Kamatani, C. Kooperberg, T.B. Harris, S.H. Jee, J. Coresh, F.J. Tsai, D.L. Longo, Y.T. Chen, J.F. Felix, Q. Yang, B.M. Psaty, E. Boerwinkle, L.C. Becker, D.O. Mook-Kanamori, J.G. Wilson, V. Gudnason, C.J. O'Donnell, A. Dehghan, L.A. Cupples, M.A. Nalls, A.P. Morris, Y. Okada, A.P. Reiner, L.I. Zon, S.K. Ganesh, Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis, American journal of human genetics, 100 (2017) 51-63.

[122] M. Hirata, Y. Kamatani, A. Nagai, Y. Kiyohara, T. Ninomiya, A. Tamakoshi, Z. Yamagata, M. Kubo, K. Muto, T. Mushiroda, Y. Murakami, K. Yuji, Y. Furukawa, H. Zembutsu, T. Tanaka, Y. Ohnishi, Y. Nakamura, G. BioBank Japan Cooperative Hospital, K. Matsuda, Cross-sectional analysis of BioBank Japan clinical data: A large cohort of 200,000 patients with 47 common diseases, J Epidemiol, (2017). S9-S21.

[121] M. Hirata, A. Nagai, Y. Kamatani, T. Ninomiya, A. Tamakoshi, Z. Yamagata, M. Kubo, K. Muto, Y. Kiyohara, T. Mushiroda, Y. Murakami, K. Yuji, Y. Furukawa, H. Zembutsu, T. Tanaka, Y. Ohnishi, Y. Nakamura, G. BioBank Japan Cooperative Hospital, K. Matsuda, Overview of BioBank Japan follow-up data in 32 diseases, J Epidemiol, (2017). S22-S28.

[120] A. Nagai, M. Hirata, Y. Kamatani, K. Muto, K. Matsuda, Y. Kiyohara, T. Ninomiya, A. Tamakoshi, Z. Yamagata, T. Mushiroda, Y. Murakami, K. Yuji, Y. Furukawa, H. Zembutsu, T. Tanaka, Y. Ohnishi, Y. Nakamura, G. BioBank Japan Cooperative Hospital, M. Kubo, Overview of the BioBank Japan Project: Study design and profile, J Epidemiol, (2017). S2-S8.

 [119] K. Nakamura, E. Okada, S. Ukawa, M. Hirata, A. Nagai, Z. Yamagata, Y. Kiyohara, K. Muto, Y. Kamatani, T. Ninomiya, K. Matsuda, M. Kubo, Y. Nakamura, G. BioBank Japan Cooperative Hospital, A. Tamakoshi, Characteristics and prognosis of Japanese female breast cancer patients: The BioBank Japan project, J Epidemiol, (2017). S58-S64.

[118] K. Nakamura, S. Ukawa, E. Okada, M. Hirata, A. Nagai, Z. Yamagata, T. Ninomiya, K. Muto, Y. Kiyohara, K. Matsuda, Y. Kamatani, M. Kubo, Y. Nakamura, G. BioBank Japan Cooperative Hospital, A. Tamakoshi, Characteristics and prognosis of Japanese male and female lung cancer patients: The BioBank Japan Project, J Epidemiol, (2017). S49-S57.

[117] A. Tamakoshi, K. Nakamura, S. Ukawa, E. Okada, M. Hirata, A. Nagai, K. Matsuda, Y. Kamatani, K. Muto, Y. Kiyohara, Z. Yamagata, T. Ninomiya, M. Kubo, Y. Nakamura, G. BioBank Japan Cooperative Hospital, Characteristics and prognosis of Japanese colorectal cancer patients: The BioBank Japan Project, J Epidemiol, (2017). S36-S42.

[116] S. Ukawa, K. Nakamura, E. Okada, M. Hirata, A. Nagai, Z. Yamagata, K. Muto, K. Matsuda, T. Ninomiya, Y. Kiyohara, Y. Kamatani, M. Kubo, Y. Nakamura, G. BioBank Japan Cooperative Hospital, A. Tamakoshi, Clinical and histopathological characteristics of patients with prostate cancer in the BioBank Japan project, J Epidemiol, (2017). S65-S70.

[115] S. Ukawa, E. Okada, K. Nakamura, M. Hirata, A. Nagai, K. Matsuda, Z. Yamagata, Y. Kamatani, T. Ninomiya, Y. Kiyohara, K. Muto, M. Kubo, Y. Nakamura, G. BioBank Japan Cooperative Hospital, A. Tamakoshi, Characteristics of patients with liver cancer in the BioBank Japan project, J Epidemiol, (2017). S43-S48.

[114] H. Yokomichi, A. Nagai, M. Hirata, Y. Kiyohara, K. Muto, T. Ninomiya, K. Matsuda, Y. Kamatani, A. Tamakoshi, M. Kubo, Y. Nakamura, G. BioBank Japan Cooperative Hospital, Z. Yamagata, Survival of macrovascular disease, chronic kidney disease, chronic respiratory disease, cancer and smoking in patients with type 2 diabetes: BioBank Japan cohort, J Epidemiol, (2017). S98-S106.

[113] H. Yokomichi, A. Nagai, M. Hirata, A. Tamakoshi, Y. Kiyohara, Y. Kamatani, K. Muto, T. Ninomiya, K. Matsuda, M. Kubo, Y. Nakamura, G. BioBank Japan Cooperative Hospital, Z. Yamagata, Statin use and all-cause and cancer mortality: BioBank Japan cohort, J Epidemiol, (2017). S84-S91.

[112] H. Yokomichi, H. Noda, A. Nagai, M. Hirata, A. Tamakoshi, Y. Kamatani, Y. Kiyohara, K. Matsuda, K. Muto, T. Ninomiya, M. Kubo, Y. Nakamura, G. BioBank Japan Cooperative Hospital, Z. Yamagata, Cholesterol levels of Japanese dyslipidaemic patients with various comorbidities: BioBank Japan, J Epidemiol, (2017). S77-S83.

[111] E. Okada, S. Ukawa, K. Nakamura, M. Hirata, A. Nagai, K. Matsuda, T. Ninomiya, Y. Kiyohara, K. Muto, Y. Kamatani, Z. Yamagata, M. Kubo, Y. Nakamura, G. BioBank Japan Cooperative Hospital, A. Tamakoshi, Demographic and lifestyle factors and survival among patients with esophageal and gastric cancer: The Biobank Japan Project, J Epidemiol, (2017). S29-S35.

[110] H. Yokomichi, A. Nagai, M. Hirata, Y. Kiyohara, K. Muto, T. Ninomiya, K. Matsuda, Y. Kamatani, A. Tamakoshi, M. Kubo, Y. Nakamura, G. BioBank Japan Cooperative Hospital, Z. Yamagata, Serum glucose, cholesterol and blood pressure levels in Japanese type 1 and 2 diabetic patients: BioBank Japan, J Epidemiol, (2017). S92-S97.

[109] J. Mori, C. Tanikawa, N. Ohnishi, Y. Funauchi, O. Toyoshima, K. Ueda, K. Matsuda, EPSIN 3, a novel p53 target, regulates the apoptotic pathway and gastric carcinogenesis, Neoplasia, 19 (2017) 185-195. 

[108] T. Hachiya, Y. Kamatani, A. Takahashi, J. Hata, R. Furukawa, Y. Shiwa, T. Yamaji, M. Hara, K. Tanno, H. Ohmomo, K. Ono, N. Takashima, K. Matsuda, K. Wakai, N. Sawada, M. Iwasaki, K. Yamagishi, T. Ago, T. Ninomiya, A. Fukushima, A. Hozawa, N. Minegishi, M. Satoh, R. Endo, M. Sasaki, K. Sakata, S. Kobayashi, K. Ogasawara, M. Nakamura, J. Hitomi, Y. Kita, K. Tanaka, H. Iso, T. Kitazono, M. Kubo, H. Tanaka, S. Tsugane, Y. Kiyohara, M. Yamamoto, K. Sobue, A. Shimizu, Genetic Predisposition to Ischemic Stroke: A Polygenic Risk Score, Stroke, 48 (2017) 253-258.

[107] M. Ikeda, A. Takahashi, Y. Kamatani, Y. Okahisa, H. Kunugi, N. Mori, T. Sasaki, T. Ohmori, Y. Okamoto, H. Kawasaki, S. Shimodera, T. Kato, H. Yoneda, R. Yoshimura, M. Iyo, K. Matsuda, M. Akiyama, K. Ashikawa, K. Kashiwase, K. Tokunaga, K. Kondo, T. Saito, A. Shimasaki, K. Kawase, T. Kitajima, K. Matsuo, M. Itokawa, T. Someya, T. Inada, R. Hashimoto, T. Inoue, K. Akiyama, H. Tanii, H. Arai, S. Kanba, N. Ozaki, I. Kusumi, T. Yoshikawa, M. Kubo, N. Iwata, A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder, Mol Psychiatry, (2017).

[106] S. Hirabayashi, K. Ohki, K. Nakabayashi, H. Ichikawa, Y. Momozawa, K. Okamura, A. Yaguchi, K. Terada, Y. Saito, A. Yoshimi, H. Ogata-Kawata, H. Sakamoto, M. Kato, J. Fujimura, M. Hino, A. Kinoshita, H. Kakuda, H. Kurosawa, K. Kato, R. Kajiwara, K. Moriwaki, T. Morimoto, K. Nakamura, Y. Noguchi, T. Osumi, K. Sakashita, J. Takita, Y. Yuza, K. Matsuda, T. Yoshida, K. Matsumoto, K. Hata, M. Kubo, Y. Matsubara, T. Fukushima, K. Koh, A. Manabe, A. Ohara, N. Kiyokawa, G. Tokyo Children's Cancer Study, ZNF384-related fusion genes define a subgroup of childhood B-cell precursor acute lymphoblastic leukemia with a characteristic immunotype, Haematologica, 102 (2017) 118-129.

2016

[105] J. Hata, A. Nagai, M. Hirata, Y. Kamatani, A. Tamakoshi, Z. Yamagata, K. Muto, K. Matsuda, M. Kubo, Y. Nakamura, G. Biobank Japan Cooperative Hospital, Y. Kiyohara, T. Ninomiya, Collaborator, Risk prediction models for mortality in patients with cardiovascular disease: The BioBank Japan project, J Epidemiol, (2016). S71-S76.

[104] C.D. Middlebrooks, A.R. Banday, K. Matsuda, K.I. Udquim, O.O. Onabajo, A. Paquin, J.D. Figueroa, B. Zhu, S. Koutros, M. Kubo, T. Shuin, N.D. Freedman, M. Kogevinas, N. Malats, S.J. Chanock, M. Garcia-Closas, D.T. Silverman, N. Rothman, L. Prokunina-Olsson, Association of germline variants in the APOBEC3 region with cancer risk and enrichment with APOBEC-signature mutations in tumors, Nat Genet, 48 (2016) 1330-1338.

[103] M.R. Han, J. Long, J.Y. Choi, S.K. Low, S.S. Kweon, Y. Zheng, Q. Cai, J. Shi, X. Guo, K. Matsuo, M. Iwasaki, C.Y. Shen, M.K. Kim, W. Wen, B. Li, A. Takahashi, M.H. Shin, Y.B. Xiang, H. Ito, Y. Kasuga, D.Y. Noh, K. Matsuda, M.H. Park, Y.T. Gao, H. Iwata, S. Tsugane, S.K. Park, M. Kubo, X.O. Shu, D. Kang, W. Zheng, Genome-wide association study in East Asians identifies two novel breast cancer susceptibility loci, Hum Mol Genet, (2016) 3361-3371.

[102] Y. Okada, A. Suzuki, K. Ikari, C. Terao, Y. Kochi, K. Ohmura, K. Higasa, M. Akiyama, K. Ashikawa, M. Kanai, J. Hirata, N. Suita, Y.Y. Teo, H. Xu, S.C. Bae, A. Takahashi, Y. Momozawa, K. Matsuda, S. Momohara, A. Taniguchi, R. Yamada, T. Mimori, M. Kubo, M.A. Brown, S. Raychaudhuri, F. Matsuda, H. Yamanaka, Y. Kamatani, K. Yamamoto, Contribution of a Non-classical HLA Gene, HLA-DOA, to the Risk of Rheumatoid Arthritis, American journal of human genetics, 99 (2016) 366-374.

[101] A. Mahajan, A.R. Rodan, T.H. Le, K.J. Gaulton, J. Haessler, A.M. Stilp, Y. Kamatani, G. Zhu, T. Sofer, S. Puri, J.N. Schellinger, P.L. Chu, S. Cechova, N. van Zuydam, S. Consortium, P. BioBank Japan, J. Arnlov, M.F. Flessner, V. Giedraitis, A.C. Heath, M. Kubo, A. Larsson, C.M. Lindgren, P.A. Madden, G.W. Montgomery, G.J. Papanicolaou, A.P. Reiner, J. Sundstrom, T.A. Thornton, L. Lind, E. Ingelsson, J. Cai, N.G. Martin, C. Kooperberg, K. Matsuda, J.B. Whitfield, Y. Okada, C.C. Laurie, A.P. Morris, N. Franceschini, Trans-ethnic Fine Mapping Highlights Kidney-Function Genes Linked to Salt Sensitivity, American journal of human genetics, 99 (2016) 636-646.

[100] T. Koguchi, C. Tanikawa, J. Mori, Y. Kojima, K. Matsuda, Regulation of myo-inositol biosynthesis by p53-ISYNA1 pathway, Int J Oncol, (2016). 2415-2424.

[99] C. Zeng, K. Matsuda, W.H. Jia, J. Chang, S.S. Kweon, Y.B. Xiang, A. Shin, S.H. Jee, D.H. Kim, B. Zhang, Q. Cai, X. Guo, J. Long, N. Wang, R. Courtney, Z.Z. Pan, C. Wu, A. Takahashi, M.H. Shin, K. Matsuo, F. Matsuda, Y.T. Gao, J.H. Oh, S. Kim, K.J. Jung, Y.O. Ahn, Z. Ren, H.L. Li, J. Wu, J. Shi, W. Wen, G. Yang, B. Li, B.T. Ji, Genetics, C. Epidemiology of Colorectal Cancer, H. Brenner, R.E. Schoen, S. Kury, S. Colorectal Transdisciplinary, S.B. Gruber, F.R. Schumacher, S.L. Stenzel, R. Colon Cancer Family, G. Casey, J.L. Hopper, M.A. Jenkins, H.R. Kim, J.Y. Jeong, J.W. Park, K. Tajima, S.H. Cho, M. Kubo, X.O. Shu, D. Lin, Y.X. Zeng, W. Zheng, Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk, Gastroenterology, (2016). 1633-1645.

[98] S.K. Low, K. Fukunaga, A. Takahashi, K. Matsuda, F. Hongo, H. Nakanishi, H. Kitamura, T. Inoue, Y. Kato, Y. Tomita, S. Fukasawa, T. Tanaka, K. Nishimura, H. Uemura, I. Hara, M. Fujisawa, H. Matsuyama, K. Hashine, K. Tatsugami, H. Enokida, M. Kubo, T. Miki, T. Mushiroda, Association Study of a Functional Variant on ABCG2 Gene with Sunitinib-Induced Severe Adverse Drug Reaction, PloS one, 11 (2016) e0148177.

[97] J. Mori, C. Tanikawa, Y. Funauchi, P.H. Lo, Y. Nakamura, K. Matsuda, Cystatin C as a p53-inducible apoptotic mediator which regulates Cathepsin L activity, Cancer Sci, (2016). 298-306.

[96] Y. Shiwa, T. Hachiya, R. Furukawa, H. Ohmomo, K. Ono, H. Kudo, J. Hata, A. Hozawa, M. Iwasaki, K. Matsuda, N. Minegishi, M. Satoh, K. Tanno, T. Yamaji, K. Wakai, J. Hitomi, Y. Kiyohara, M. Kubo, H. Tanaka, S. Tsugane, M. Yamamoto, K. Sobue, A. Shimizu, Adjustment of Cell-Type Composition Minimizes Systematic Bias in Blood DNA Methylation Profiles Derived by DNA Collection Protocols, PloS one, 11 (2016) e0147519.

2105

[95] K. Matsuda, A. Takahashi, C.D. Middlebrooks, W. Obara, Y. Nasu, K. Inoue, K. Tamura, I. Yamasaki, Y. Naya, C. Tanikawa, R. Cui, J.D. Figueroa, D.T. Silverman, N. Rothman, M. Namiki, Y. Tomita, H. Nishiyama, K. Kohri, T. Deguchi, M. Nakagawa, M. Yokoyama, T. Miki, H. Kumon, T. Fujioka, L. Prokunina-Olsson, M. Kubo, Y. Nakamura, T. Shuin, Genome-wide association study identified SNP on 15q24 associated with bladder cancer risk in Japanese population, Hum Mol Genet, 24 (2015) 1177-1184.

[94] P.H. Lo, C. Tanikawa, T. Katagiri, Y. Nakamura, K. Matsuda, Identification of novel epigenetically inactivated gene PAMR1 in breast carcinoma, Oncol Rep, 33 (2015) 267-273.

[93] Y. Okada, Y. Momozawa, K. Ashikawa, M. Kanai, K. Matsuda, Y. Kamatani, A. Takahashi, M. Kubo, Construction of a population-specific HLA imputation reference panel and its application to Graves' disease risk in Japanese, Nat Genet, 47 (2015) 798-802.

[92] H. Fang, R. Yamaguchi, X. Liu, Y. Daigo, P.Y. Yew, C. Tanikawa, K. Matsuda, S. Imoto, S. Miyano, Y. Nakamura, Quantitative T cell repertoire analysis by deep cDNA sequencing of T cell receptor alpha and beta chains using next-generation sequencing (NGS), Oncoimmunology, 3 (2014) e968467.

[91] Y.K. Kim, J.H. Oh, Y.J. Kim, M.Y. Hwang, S. Moon, S.K. Low, A. Takahashi, K. Matsuda, M. Kubo, J. Lee, B.J. Kim, Influence of Genetic Variants in EGF and Other Genes on Hematological Traits in Korean Populations by a Genome-Wide Approach, Biomed Res Int, 2015 (2015) 914965.

[90] P.K. Joshi, T. Esko, H. Mattsson, N. Eklund, I. Gandin, T. Nutile, A.U. Jackson, C. Schurmann, A.V. Smith, W. Zhang, Y. Okada, A. Stancakova, J.D. Faul, W. Zhao, T.M. Bartz, M.P. Concas, N. Franceschini, S. Enroth, V. Vitart, S. Trompet, X. Guo, D.I. Chasman, J.R. O'Connel, T. Corre, S.S. Nongmaithem, Y. Chen, M. Mangino, D. Ruggiero, M. Traglia, A.E. Farmaki, T. Kacprowski, A. Bjonnes, A. van der Spek, Y. Wu, A.K. Giri, L.R. Yanek, L. Wang, E. Hofer, C.A. Rietveld, O. McLeod, M.C. Cornelis, C. Pattaro, N. Verweij, C. Baumbach, A. Abdellaoui, H.R. Warren, D. Vuckovic, H. Mei, C. Bouchard, J.R. Perry, S. Cappellani, S.S. Mirza, M.C. Benton, U. Broeckel, S.E. Medland, P.A. Lind, G. Malerba, A. Drong, L. Yengo, L.F. Bielak, D. Zhi, P.J. van der Most, D. Shriner, R. Magi, G. Hemani, T. Karaderi, Z. Wang, T. Liu, I. Demuth, J.H. Zhao, W. Meng, L. Lataniotis, S.W. van der Laan, J.P. Bradfield, A.R. Wood, A. Bonnefond, T.S. Ahluwalia, L.M. Hall, E. Salvi, S. Yazar, L. Carstensen, H.G. de Haan, M. Abney, U. Afzal, M.A. Allison, N. Amin, F.W. Asselbergs, S.J. Bakker, R.G. Barr, S.E. Baumeister, D.J. Benjamin, S. Bergmann, E. Boerwinkle, E.P. Bottinger, A. Campbell, A. Chakravarti, Y. Chan, S.J. Chanock, C. Chen, Y.D. Chen, F.S. Collins, J. Connell, A. Correa, L.A. Cupples, G.D. Smith, G. Davies, M. Dorr, G. Ehret, S.B. Ellis, B. Feenstra, M.F. Feitosa, I. Ford, C.S. Fox, T.M. Frayling, N. Friedrich, F. Geller, G. Scotland, I. Gillham-Nasenya, O. Gottesman, M. Graff, F. Grodstein, C. Gu, C. Haley, C.J. Hammond, S.E. Harris, T.B. Harris, N.D. Hastie, N.L. Heard-Costa, K. Heikkila, L.J. Hocking, G. Homuth, J.J. Hottenga, J. Huang, J.E. Huffman, P.G. Hysi, M.A. Ikram, E. Ingelsson, A. Joensuu, A. Johansson, P. Jousilahti, J.W. Jukema, M. Kahonen, Y. Kamatani, S. Kanoni, S.M. Kerr, N.M. Khan, P. Koellinger, H.A. Koistinen, M.K. Kooner, M. Kubo, J. Kuusisto, J. Lahti, L.J. Launer, R.A. Lea, B. Lehne, T. Lehtimaki, D.C. Liewald, L. Lind, M. Loh, M.L. Lokki, S.J. London, S.J. Loomis, A. Loukola, Y. Lu, T. Lumley, A. Lundqvist, S. Mannisto, P. Marques-Vidal, C. Masciullo, A. Matchan, R.A. Mathias, K. Matsuda, J.B. Meigs, C. Meisinger, T. Meitinger, C. Menni, F.D. Mentch, E. Mihailov, L. Milani, M.E. Montasser, G.W. Montgomery, A. Morrison, R.H. Myers, R. Nadukuru, P. Navarro, M. Nelis, M.S. Nieminen, I.M. Nolte, G.T. O'Connor, A. Ogunniyi, S. Padmanabhan, W.R. Palmas, J.S. Pankow, I. Patarcic, F. Pavani, P.A. Peyser, K. Pietilainen, N. Poulter, I. Prokopenko, S. Ralhan, P. Redmond, S.S. Rich, H. Rissanen, A. Robino, L.M. Rose, R. Rose, C. Sala, B. Salako, V. Salomaa, A.P. Sarin, R. Saxena, H. Schmidt, L.J. Scott, W.R. Scott, B. Sennblad, S. Seshadri, P. Sever, S. Shrestha, B.H. Smith, J.A. Smith, N. Soranzo, N. Sotoodehnia, L. Southam, A.V. Stanton, M.G. Stathopoulou, K. Strauch, R.J. Strawbridge, M.J. Suderman, N. Tandon, S.T. Tang, K.D. Taylor, B.O. Tayo, A.M. Toglhofer, M. Tomaszewski, N. Tsernikova, J. Tuomilehto, A.G. Uitterlinden, D. Vaidya, A. van Hylckama Vlieg, J. van Setten, T. Vasankari, S. Vedantam, E. Vlachopoulou, D. Vozzi, E. Vuoksimaa, M. Waldenberger, E.B. Ware, W. Wentworth-Shields, J.B. Whitfield, S. Wild, G. Willemsen, C.S. Yajnik, J. Yao, G. Zaza, X. Zhu, P. BioBank Japan, R.M. Salem, M. Melbye, H. Bisgaard, N.J. Samani, D. Cusi, D.A. Mackey, R.S. Cooper, P. Froguel, G. Pasterkamp, S.F. Grant, H. Hakonarson, L. Ferrucci, R.A. Scott, A.D. Morris, C.N. Palmer, G. Dedoussis, P. Deloukas, L. Bertram, U. Lindenberger, S.I. Berndt, C.M. Lindgren, N.J. Timpson, A. Tonjes, P.B. Munroe, T.I. Sorensen, C.N. Rotimi, D.K. Arnett, A.J. Oldehinkel, S.L. Kardia, B. Balkau, G. Gambaro, A.P. Morris, J.G. Eriksson, M.J. Wright, N.G. Martin, S.C. Hunt, J.M. Starr, I.J. Deary, L.R. Griffiths, H. Tiemeier, N. Pirastu, J. Kaprio, N.J. Wareham, L. Perusse, J.G. Wilson, G. Girotto, M.J. Caulfield, O. Raitakari, D.I. Boomsma, C. Gieger, P. van der Harst, A.A. Hicks, P. Kraft, J. Sinisalo, P. Knekt, M. Johannesson, P.K. Magnusson, A. Hamsten, R. Schmidt, I.B. Borecki, E. Vartiainen, D.M. Becker, D. Bharadwaj, K.L. Mohlke, M. Boehnke, C.M. van Duijn, D.K. Sanghera, A. Teumer, E. Zeggini, A. Metspalu, P. Gasparini, S. Ulivi, C. Ober, D. Toniolo, I. Rudan, D.J. Porteous, M. Ciullo, T.D. Spector, C. Hayward, J. Dupuis, R.J. Loos, A.F. Wright, G.R. Chandak, P. Vollenweider, A.R. Shuldiner, P.M. Ridker, J.I. Rotter, N. Sattar, U. Gyllensten, K.E. North, M. Pirastu, B.M. Psaty, D.R. Weir, M. Laakso, V. Gudnason, A. Takahashi, J.C. Chambers, J.S. Kooner, D.P. Strachan, H. Campbell, J.N. Hirschhorn, M. Perola, O. Polasek, J.F. Wilson, Directional dominance on stature and cognition in diverse human populations, Nature, 523 (2015) 459-462.

[89] Y. Funauchi, C. Tanikawa, P.H. Yi Lo, J. Mori, Y. Daigo, A. Takano, Y. Miyagi, A. Okawa, Y. Nakamura, K. Matsuda, Regulation of iron homeostasis by the p53-ISCU pathway, Scientific reports, 5 (2015) 16497.

[88] M. Wang, A. Takahashi, F. Liu, D. Ye, Q. Ding, C. Qin, C. Yin, Z. Zhang, K. Matsuda, M. Kubo, R. Na, X. Lin, H. Jiang, S. Ren, J. Sun, S.L. Zheng, L.L. Marchand, W.B. Isaacs, Z. Mo, C.A. Haiman, Y. Sun, H. Nakagawa, J. Xu, Large-scale association analysis in Asians identifies new susceptibility loci for prostate cancer, Nature communications, 6 (2015) 8469. 

2014

[87] Z. Deng, K. Matsuda, C. Tanikawa, J. Lin, Y. Furukawa, R. Hamamoto, Y. Nakamura, Late Cornified Envelope Group I, a Novel Target of p53, Regulates PRMT5 Activity, Neoplasia, 16 (2014) 656-664.

[86] M.F. Keller, A.P. Reiner, Y. Okada, F.J. van Rooij, A.D. Johnson, M.H. Chen, A.V. Smith, A.P. Morris, T. Tanaka, L. Ferrucci, A.B. Zonderman, G. Lettre, T. Harris, M. Garcia, S. Bandinelli, R. Qayyum, L.R. Yanek, D.M. Becker, L.C. Becker, C. Kooperberg, B. Keating, J. Reis, H. Tang, E. Boerwinkle, Y. Kamatani, K. Matsuda, N. Kamatani, Y. Nakamura, M. Kubo, S. Liu, A. Dehghan, J.F. Felix, A. Hofman, A.G. Uitterlinden, C.M. van Duijn, O.H. Franco, D.L. Longo, A.B. Singleton, B.M. Psaty, M.K. Evans, L.A. Cupples, J.I. Rotter, C.J. O'Donnell, A. Takahashi, J.G. Wilson, S.K. Ganesh, M.A. Nalls, Trans-ethnic meta-analysis of white blood cell phenotypes, Hum Mol Genet, (2014). 6944-6960.

 [85]Q. Cai, B. Zhang, H. Sung, S.K. Low, S.S. Kweon, W. Lu, J. Shi, J. Long, W. Wen, J.Y. Choi, D.Y. Noh, C.Y. Shen, K. Matsuo, S.H. Teo, M.K. Kim, U.S. Khoo, M. Iwasaki, M. Hartman, A. Takahashi, K. Ashikawa, K. Matsuda, M.H. Shin, M.H. Park, Y. Zheng, Y.B. Xiang, B.T. Ji, S.K. Park, P.E. Wu, C.N. Hsiung, H. Ito, Y. Kasuga, P. Kang, S. Mariapun, S.H. Ahn, H.S. Kang, K.Y. Chan, E.P. Man, H. Iwata, S. Tsugane, H. Miao, J. Liao, Y. Nakamura, M. Kubo, R.J. Delahanty, Y. Zhang, B. Li, C. Li, Y.T. Gao, X.O. Shu, D. Kang, W. Zheng, Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1. Nat Genet (2014). 886-890.

[84]M. Hirokawa, H. Morita, T. Tajima, A. Takahashi, K. Ashikawa, F. Miya, D. Shigemizu, K. Ozaki, Y. Sakata, D. Nakatani, S. Suna, Y. Imai, T. Tanaka, T. Tsunoda, K. Matsuda, T. Kadowaki, Y. Nakamura, R. Nagai, I. Komuro, M. Kubo, A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese. Eur J Hum Genet (2014). 374-380.

[83]T. Fujitomo, Y. Daigo, K. Matsuda, K. Ueda, Y. Nakamura, Identification of a nuclear protein, LRRC42, involved in lung carcinogenesis. Int J Oncol 45 (2014) 147-156.

[82]Y. Yamamoto, M. Miyamoto, D. Tatsuda, M. Kubo, H. Nakagama, Y. Nakamura, H. Satoh, K. Matsuda, T. Watanabe, T. Ohta, A rare polymorphic variant of NBS1 reduces DNA repair activity and elevates chromosomal instability. Cancer Res (2014). 3707-3715.

[81]B. Zhang, W.H. Jia, K. Matsuda, S.S. Kweon, K. Matsuo, Y.B. Xiang, A. Shin, S.H. Jee, D.H. Kim, Q. Cai, J. Long, J. Shi, W. Wen, G. Yang, Y. Zhang, C. Li, B. Li, Y. Guo, Z. Ren, B.T. Ji, Z.Z. Pan, A. Takahashi, M.H. Shin, F. Matsuda, Y.T. Gao, J.H. Oh, S. Kim, Y.O. Ahn, A.T. Chan, J. Chang-Claude, M.L. Slattery, S.B. Gruber, F.R. Schumacher, S.L. Stenzel, G. Casey, H.R. Kim, J.Y. Jeong, J.W. Park, H.L. Li, S. Hosono, S.H. Cho, M. Kubo, X.O. Shu, Y.X. Zeng, W. Zheng, Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk. Nat Genet 46 (2014) 533-542.

[80]J. Lin, Z. Deng, C. Tanikawa, T. Shuin, T. Miki, K. Matsuda, Y. Nakamura, Downregulation of the tumor suppressor HSPB7, involved in the p53 pathway, in renal cell carcinoma by hypermethylation. Int J Oncol (2014). 1490-1498.

[79]T. Kashiyama, K. Oda, Y. Ikeda, Y. Shiose, Y. Hirota, K. Inaba, C. Makii, R. Kurikawa, A. Miyasaka, T. Koso, T. Fukuda, M. Tanikawa, K. Shoji, K. Sone, T. Arimoto, O. Wada-Hiraike, K. Kawana, S. Nakagawa, K. Matsuda, F. McCormick, H. Aburatani, T. Yano, Y. Osuga, T. Fujii, Antitumor Activity and Induction of TP53-Dependent Apoptosis toward Ovarian Clear Cell Adenocarcinoma by the Dual PI3K/mTOR Inhibitor DS-7423. PloS one 9 (2014) e87220.

[78]B. Zhang, W.H. Jia, K. Matsuo, A. Shin, Y.B. Xiang, K. Matsuda, S.H. Jee, D.H. Kim, P.Y. Cheah, Z. Ren, Q. Cai, J. Long, J. Shi, W. Wen, G. Yang, B.T. Ji, Z.Z. Pan, F. Matsuda, Y.T. Gao, J.H. Oh, Y.O. Ahn, M. Kubo, L.F. Thean, E.J. Park, H.L. Li, J.W. Park, J. Jo, J.Y. Jeong, S. Hosono, Y. Nakamura, X.O. Shu, Y.X. Zeng, W. Zheng, Genome-wide association study identifies a new SMAD7 risk variant associated with colorectal cancer risk in East Asians. International journal of cancer. Journal international du cancer (2014). 948-955.

2013

[77]T. Yasui, A. Okada, Y. Urabe, M. Usami, K. Mizuno, Y. Kubota, K. Tozawa, S. Sasaki, Y. Higashi, Y. Sato, M. Kubo, Y. Nakamura, K. Matsuda, K. Kohri, A replication study for three nephrolithiasis loci at 5q35.3, 7p14.3 and 13q14.1 in the Japanese population. J Hum Genet 58 (2013) 588-593.

[76]C.M. O'Seaghdha, H. Wu, Q. Yang, K. Kapur, I. Guessous, A.M. Zuber, A. Kottgen, C. Stoudmann, A. Teumer, Z. Kutalik, M. Mangino, A. Dehghan, W. Zhang, G. Eiriksdottir, G. Li, T. Tanaka, L. Portas, L.M. Lopez, C. Hayward, K. Lohman, K. Matsuda, S. Padmanabhan, D. Firsov, R. Sorice, S. Ulivi, A.C. Brockhaus, M.E. Kleber, A. Mahajan, F.D. Ernst, V. Gudnason, L.J. Launer, A. Mace, E. Boerwinckle, D.E. Arking, C. Tanikawa, Y. Nakamura, M.J. Brown, J.M. Gaspoz, J.M. Theler, D.S. Siscovick, B.M. Psaty, S. Bergmann, P. Vollenweider, V. Vitart, A.F. Wright, T. Zemunik, M. Boban, I. Kolcic, P. Navarro, E.M. Brown, K. Estrada, J. Ding, T.B. Harris, S. Bandinelli, D. Hernandez, A.B. Singleton, G. Girotto, D. Ruggiero, A.P. d'Adamo, A. Robino, T. Meitinger, C. Meisinger, G. Davies, J.M. Starr, J.C. Chambers, B.O. Boehm, B.R. Winkelmann, J. Huang, F. Murgia, S.H. Wild, H. Campbell, A.P. Morris, O.H. Franco, A. Hofman, A.G. Uitterlinden, F. Rivadeneira, U. Volker, A. Hannemann, R. Biffar, W. Hoffmann, S.Y. Shin, P. Lescuyer, H. Henry, C. Schurmann, P.B. Munroe, P. Gasparini, N. Pirastu, M. Ciullo, C. Gieger, W. Marz, L. Lind, T.D. Spector, A.V. Smith, I. Rudan, J.F. Wilson, O. Polasek, I.J. Deary, M. Pirastu, L. Ferrucci, Y. Liu, B. Kestenbaum, J.S. Kooner, J.C. Witteman, M. Nauck, W.H. Kao, H. Wallaschofski, O. Bonny, C.S. Fox, M. Bochud, Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations. PLoS Genet 9 (2013) e1003796.

[75]J. Wang, L.G. Carvajal-Carmona, J.H. Chu, A.G. Zauber, A.T. Collaborators, M. Kubo, K. Matsuda, M. Dunlop, R.S. Houlston, O.M. Sieber, L. Lipton, P. Gibbs, N.G. Martin, G.W. Montgomery, J.P. Young, P.N. Baird, M.J. Ratain, Y. Nakamura, S. Weiss, I. Tomlinson, M.M. Bertagnolli, Germline Variants and Advanced Colorectal Adenomas: Adenoma Prevention with Celecoxib Trial Genomewide Association Study. Clin Cancer Res (2013). 6430-6437.

[74] S. W. Yee, J. A. Mefford, N. Singh, M. E. Percival, A. Stecula, K. Yang, J. S. Witte, A. Takahashi, M. Kubo, K. Matsuda, K. M. Giacomini, C. Andreadis "Impact of polymorphisms in drug pathway genes on disease-free survival in adults with acute myeloid leukemia. J Hum Genet, 58 (2013) 353-361.

[73]C. Tanikawa, K. Matsuo, M. Kubo, A. Takahashi, H. Ito, H. Tanaka, Y. Yatabe, K. Yamao, N. Kamatani, K. Tajima, Y. Nakamura, K. Matsuda, Impact of PSCA variation on gastric ulcer susceptibility. PloS one 8(2013): e63698.

[72]C. Tanikawa*, Y. Okada*, A. Takahashi, K. Oda, N. Kamatani, M. Kubo, Y. Nakamura, K. Matsuda, Genome wide association study of age at menarche in the Japanese population. PloS one 8(2013): e63821. *These authors equally contributed to this work.

[71]P.H. Yi Lo, Y. Urabe, V. Kumar, C. Tanikawa, K. Koike, N. Kato, D. Miki, K. Chayama, M. Kubo, Y. Nakamura, K. Matsuda, Identification of a functional variant in the MICA promoter which regulates MICA expression and increases HCV-related hepatocellular carcinoma risk. PloS one  8(2013): e61279.

[70]D. Kang, H.S. Cho, G. Toyokawa, M. Kogure, Y. Yamane, Y. Iwai, S. Hayami, T. Tsunoda, H.I. Field, K. Matsuda, D.E. Neal, B.A. Ponder, Y. Maehara, Y. Nakamura, R. Hamamoto, The histone methyltransferase Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1) is involved in human carcinogenesis. Genes Chromosomes Cancer 52 (2013) 126-139.

[69]A. Aarnink, H.J. Garchon, Y. Okada, A. Takahashi, K. Matsuda, M. Kubo, Y. Nakamura, A. Blancher, Comparative analysis in cynomolgus macaque identifies a novel human MHC locus controlling platelet blood counts independently of BAK1. Journal of thrombosis and haemostasis:11 (2013) 384-386.

[68]R. Takata, K. Matsuda, J. Sugimura, W. Obara, T. Fujioka, K. Okihara, N. Takaha, T. Miki, S. Ashida, K. Inoue, C. Tanikawa, T. Shuin, S. Sasaki, Y. Kojima, K. Kohri, M. Kubo, M. Yamaguchi, Y. Ohnishi, Y. Nakamura, Impact of four loci on serum tamsulosin hydrochloride concentration. J Hum Genet 58 (2013) 21-26.

[67]Y. Urabe, H. Ochi, N. Kato, V. Kumar, A. Takahashi, R. Muroyama, N. Hosono, M. Otsuka, R. Tateishi, P.H. Lo, C. Tanikawa, M. Omata, K. Koike, D. Miki, H. Abe, N. Kamatani, J. Toyota, H. Kumada, M. Kubo, K. Chayama, Y. Nakamura, K. Matsuda, A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region. Journal of hepatology  58 (2013)875-82. 

2012

[66]C. Tanikawa, H. Nakagawa, Y. Furukawa, Y. Nakamura, K. Matsuda, CLCA2 as a p53-inducible senescence mediator. Neoplasia 14 (2012) 141-149.

[65]A. Toyama, H. Nakagawa, K. Matsuda, T.A. Sato, Y. Nakamura, K. Ueda, Quantitative Structural Characterization of Local N-Glycan Microheterogeneity in Therapeutic Antibodies by Energy-Resolved Oxonium Ion Monitoring. Analytical chemistry 84 (2012) 9655-9662.

[64]V. Kumar, P.H. Yi Lo, H. Sawai, N. Kato, A. Takahashi, Z. Deng, Y. Urabe, H. Mbarek, K. Tokunaga, Y. Tanaka, M. Sugiyama, M. Mizokami, R. Muroyama, R. Tateishi, M. Omata, K. Koike, C. Tanikawa, N. Kamatani, M. Kubo, Y. Nakamura, K. Matsuda, Soluble MICA and a MICA variation as possible prognostic biomarkers for HBV-induced hepatocellular carcinoma. PloS one 7 (2012) e44743.

[63]T. Fujitomo, Y. Daigo, K. Matsuda, K. Ueda, Y. Nakamura, Critical function for nuclear envelope protein TMEM209 in human pulmonary carcinogenesis. Cancer Res 72 (2012) 4110-4118.

[62]W. Osman, Y. Okada, Y. Kamatani, M. Kubo, K. Matsuda, Y. Nakamura, Association of common variants in TNFRSF13B, TNFSF13, and ANXA3 with serum levels of non-albumin protein and immunoglobulin isotypes in Japanese. PloS one 7 (2012) e32683.

[61]M.G. Dunlop, S.E. Dobbins, S.M. Farrington, A.M. Jones, C. Palles, N. Whiffin, A. Tenesa, S. Spain, P. Broderick, L.Y. Ooi, E. Domingo, C. Smillie, M. Henrion, M. Frampton, L. Martin, G. Grimes, M. Gorman, C. Semple, Y.P. Ma, E. Barclay, J. Prendergast, J.B. Cazier, B. Olver, S. Penegar, S. Lubbe, I. Chander, L.G. Carvajal-Carmona, S. Ballereau, A. Lloyd, J. Vijayakrishnan, L. Zgaga, I. Rudan, E. Theodoratou, H. Thomas, E. Maher, G. Evans, L. Walker, D. Halliday, A. Lucassen, J. Paterson, S. Hodgson, T. Homfray, L. Side, L. Izatt, A. Donaldson, S. Tomkins, P. Morrison, C. Brewer, A. Henderson, R. Davidson, V. Murday, J. Cook, N. Haites, T. Bishop, E. Sheridan, A. Green, C. Marks, S. Carpenter, M. Broughton, L. Greenhalge, M. Suri, J.M. Starr, I. Deary, I. Kirac, D. Kovacevic, L.A. Aaltonen, L. Renkonen-Sinisalo, J.P. Mecklin, K. Matsuda, Y. Nakamura, Y. Okada, S. Gallinger, D.J. Duggan, D. Conti, P. Newcomb, J. Hopper, M.A. Jenkins, F. Schumacher, G. Casey, D. Easton, M. Shah, P. Pharoah, A. Lindblom, T. Liu, D. Edler, C. Lenander, J. Dalen, F. Hjern, N. Lundqvist, U. Lindforss, L. Pahlman, K. Smedh, A. Tornqvist, J. Holm, M. Janson, M. Andersson, S. Ekelund, L. Olsson, C.G. Smith, H. West, J.P. Cheadle, G. Macdonald, L.M. Samuel, A. Ahmad, P. Corrie, D. Jodrell, C. Palmer, C. Wilson, J. O'Hagan, D. Smith, R. McDermott, J. Walshe, J. Cassidy, A. McDonald, N. Mohammed, J. White, H. Yosef, O. Breathnach, L. Grogan, R. Thomas, M. Eatock, P. Henry, R. Houston, P. Johnston, R. Wilson, I. Geh, F. Danwata, A. Hindley, S. Susnerwala, C. Bradley, A. Conn, A. Raine, C. Twelves, S. Falk, K. Hopkins, S. Tahir, A. Dhadda, A. Maraveyas, J. Sgouros, M. Teo, R. Ahmad, S. Cleator, A. Creak, C. Lowdell, P. Riddle, K. Benstead, D. Farrugia, N. Reed, S. Shepherd, E. Levine, S. Mullamitha, M. Saunders, J. Valle, G. Wilson, A. Jones, A. Weaver, P.I. Clark, B. Haylock, M.I. Iqbal, A.S. Myint, S. Beesley, T. Sevitt, J. Nicoll, F. Daniel, V. Ford, T. Talbot, M. Butt, A. Hamid, P. Mack, R. Roy, R. Osborne, F. McKinna, H. Alsab, D. Basu, P. Murray, B. Sizer, F.A. Azam, R. Neupane, A. Waterston, J. Glaholm, C. Blesing, S. Lowndes, A. Medisetti, A. Gaya, M. Leslie, N. Maisey, P. Ross, G. Dunn, O. Al-Salihi, H.S. Wasan, L.T. Tan, J. Dent, U. Hofmann, J.K. Joffe, E. Sherwin, R. Soomal, A. Chakrabarti, S. Joseph, J. Van der Voet, N.J. Wadd, D. Wilson, S. Anjarwalia, J. Hall, R. Hughes, A. Polychronis, J.H. Scarffe, M. Hill, R.D. James, R. Shah, J. Summers, A. Hartley, D. Carney, J. McCaffrey, B. Bystricky, S. O'Reilly, R. Gupta, T. Al-Mishlab, F. Gidden, R. O'Hara, J. Stewart, R. Ashford, R. Glynne-Jones, M. Harrison, S. Mawdsley, H. Barlow, M. Tighe, J. Walther, J. Neal, C. Rees, J. Bridgewater, S. Karp, U. McGovern, P.J. Atherton, H. El-Deeb, C. Macmillan, K. Patel, E.M. Bessell, P.D. Dickinson, V. Potter, C. Jephcott, K. McAdam, J. Wrigley, S. Muthuramalingam, A. O'Callaghan, L. Melcher, C. Braconi, J.I. Geh, D. Palmer, P. Narayana, N. Steven, S. Rudman, P. Chakraborti, K. Kelly, C. Macgregor, D. Whillis, A. Freebairn, J. Gildersleve, S. Sharif, G. Astras, T. Hickish, D. Beech, R. Ellis, R. Kulkarni, K. Shankland, R. Begent, A. Mayer, T. Meyer, S. Strauss, V. Hall, S. Raj, I. Chau, D. Cunningham, A. Birtle, A. Biswas, M. Wise, S. Cummins, S. Essapen, G. Middleton, C. Topham, R. Langley, A. Webb, M. Wilkins, T.J. Iveson, C. Askill, J. Wagstaff, A. Azzabi, A. Bateman, J. Prejbisz, D. Tsang, N. Ali, P. O'Neill, C. Cottrill, D. Propper, F.J. Lofts, J. Kennedy, D.A. Anthoney, R. Cooper, A. Crellin, A. Melcher, M. Seymour, C. Baughan, E. Alexander, J. Crown, D. Fennelly, F. Adab, S. Giridharan, I. Pedley, K. Wright, P. Bliss, G. Cogill, N. Lo, E. Toy, D. Hochhauser, J. Ledermann, A. Brewster, T. Maughan, D. Mort, S. Mukherjee, W. Dobrowsky, P. Calvert, G. Leonard, H. Ford, A.M. Moody, S. Goriah, S. Clive, L. Dawson, C. McLean, H.A. Phillips, K. Gopi, M. Tomlinson, S. Clenton, D. Furniss, J. Hornbuckle, S. Pledge, J. Wadsley, M. Abbas, E. Marshall, C. Harper-Wynne, A. Barnes, S. Kumar, V. Vigneswaran, S. Gollins, M. Genton, G. Sparrow, C. Bale, C. Fuller, A. Mullard, N. Stuart, R. Williams, M. Keane, H. Wasan, R. Adams, A. Madi, E. Hodgkinson, P. Rogers, M. Pope, R. Kaplan, A. Meade, M. Parmar, S. Kenny, D. Fisher, L. Harper, J. Mitchell, L. Nichols, B. Sydes, L. Clement, E. Kay, C. Courtney, M. Gallagher, C. Murphy, L. Thompson, S. Beall, S. Hassan, R. Gracie, G. Griffiths, M. Mason, C. Parker, R. Rudd, P. Johnson, J. Whelan, J. Northover, J. Brown, M. Aapro, R. Stout, R. Midgley, D.J. Kerr, H. Campbell, I.P. Tomlinson, R.S. Houlston, Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk. Nature genetics 44 (2012) 770-776.

[60]H. Sawai, N. Nishida, H. Mbarek, K. Matsuda, Y. Mawatari, M. Yamaoka, S. Hige, J.H. Kang, K. Abe, S. Mochida, M. Watanabe, M. Kurosaki, Y. Asahina, N. Izumi, M. Honda, S. Kaneko, E. Tanaka, K. Matsuura, Y. Itoh, E. Mita, M. Korenaga, K. Hino, Y. Murawaki, Y. Hiasa, T. Ide, K. Ito, M. Sugiyama, S.H. Ahn, K.H. Han, J.Y. Park, M.F. Yuen, Y. Nakamura, Y. Tanaka, M. Mizokami, K. Tokunaga, No association for Chinese HBV-related hepatocellular carcinoma susceptibility SNP in other East Asian populations. BMC medical genetics 13 (2012) 47.

[59]R.S. Houlston, COGENT (COlorectal cancer GENeTics) revisited. Mutagenesis 27 (2012) 143-151.

[58]Y. Okada, K. Shimane, Y. Kochi, T. Tahira, A. Suzuki, K. Higasa, A. Takahashi, T. Horita, T. Atsumi, T. Ishii, A. Okamoto, K. Fujio, M. Hirakata, H. Amano, Y. Kondo, S. Ito, K. Takada, A. Mimori, K. Saito, M. Kamachi, Y. Kawaguchi, K. Ikari, O.W. Mohammed, K. Matsuda, C. Terao, K. Ohmura, K. Myouzen, N. Hosono, T. Tsunoda, N. Nishimoto, T. Mimori, F. Matsuda, Y. Tanaka, T. Sumida, H. Yamanaka, Y. Takasaki, T. Koike, T. Horiuchi, K. Hayashi, M. Kubo, N. Kamatani, R. Yamada, Y. Nakamura, K. Yamamoto, A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese. PLoS Genet 8 (2012) e1002455.

[57]C. Tanikawa, M. Espinosa, A. Suzuki, K. Masuda, K. Yamamoto, E. Tsuchiya, K. Ueda, Y. Daigo, Y. Nakamura, K. Matsuda, Regulation of histone modification and chromatin structure by the p53-PADI4 pathway. Nature communications 3 (2012) 676.

[56]C. Tanikawa, Y. Urabe, K. Matsuo, M. Kubo, A. Takahashi, H. Ito, K. Tajima, N. Kamatani, Y. Nakamura, K. Matsuda, A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population. Nat Genet 44 (2012) 430-434, S431-432.

[55]Y. Urabe, C. Tanikawa, A. Takahashi, Y. Okada, T. Morizono, T. Tsunoda, N. Kamatani, K. Kohri, K. Chayama, M. Kubo, Y. Nakamura, K. Matsuda, A genome-wide association study of nephrolithiasis in the Japanese population identifies novel susceptible Loci at 5q35.3, 7p14.3, and 13q14.1. PLoS Genet 8 (2012) e1002541. 

2011

[54]J.C. Chambers, W. Zhang, J. Sehmi, X. Li, M.N. Wass, P. Van der Harst, H. Holm, S. Sanna, M. Kavousi, S.E. Baumeister, L.J. Coin, G. Deng, C. Gieger, N.L. Heard-Costa, J.J. Hottenga, B. Kuhnel, V. Kumar, V. Lagou, L. Liang, J. Luan, P.M. Vidal, I. Mateo Leach, P.F. O'Reilly, J.F. Peden, N. Rahmioglu, P. Soininen, E.K. Speliotes, X. Yuan, G. Thorleifsson, B.Z. Alizadeh, L.D. Atwood, I.B. Borecki, M.J. Brown, P. Charoen, F. Cucca, D. Das, E.J. de Geus, A.L. Dixon, A. Doring, G. Ehret, G.I. Eyjolfsson, M. Farrall, N.G. Forouhi, N. Friedrich, W. Goessling, D.F. Gudbjartsson, T.B. Harris, A.L. Hartikainen, S. Heath, G.M. Hirschfield, A. Hofman, G. Homuth, E. Hypponen, H.L. Janssen, T. Johnson, A.J. Kangas, I.P. Kema, J.P. Kuhn, S. Lai, M. Lathrop, M.M. Lerch, Y. Li, T.J. Liang, J.P. Lin, R.J. Loos, N.G. Martin, M.F. Moffatt, G.W. Montgomery, P.B. Munroe, K. Musunuru, Y. Nakamura, C.J. O'Donnell, I. Olafsson, B.W. Penninx, A. Pouta, B.P. Prins, I. Prokopenko, R. Puls, A. Ruokonen, M.J. Savolainen, D. Schlessinger, J.N. Schouten, U. Seedorf, S. Sen-Chowdhry, K.A. Siminovitch, J.H. Smit, T.D. Spector, W. Tan, T.M. Teslovich, T. Tukiainen, A.G. Uitterlinden, M.M. Van der Klauw, R.S. Vasan, C. Wallace, H. Wallaschofski, H.E. Wichmann, G. Willemsen, P. Wurtz, C. Xu, L.M. Yerges-Armstrong, G.R. Abecasis, K.R. Ahmadi, D.I. Boomsma, M. Caulfield, W.O. Cookson, C.M. van Duijn, P. Froguel, K. Matsuda, M.I. McCarthy, C. Meisinger, V. Mooser, K.H. Pietilainen, G. Schumann, H. Snieder, M.J. Sternberg, R.P. Stolk, H.C. Thomas, U. Thorsteinsdottir, M. Uda, G. Waeber, N.J. Wareham, D.M. Waterworth, H. Watkins, J.B. Whitfield, J.C. Witteman, B.H. Wolffenbuttel, C.S. Fox, M. Ala-Korpela, K. Stefansson, P. Vollenweider, H. Volzke, E.E. Schadt, J. Scott, M.R. Jarvelin, P. Elliott, J.S. Kooner, Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat Genet 43 (2011) 1131-1138.

[53]H. Mbarek, H. Ochi, Y. Urabe, V. Kumar, M. Kubo, N. Hosono, A. Takahashi, Y. Kamatani, D. Miki, H. Abe, T. Tsunoda, N. Kamatani, K. Chayama, Y. Nakamura, K. Matsuda, A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population, Hum Mol Genet 20 (2011) 3884-3892.

[52]S.K. Low, H. Zembutsu, A. Takahashi, N. Kamatani, P.C. Cha, N. Hosono, M. Kubo, K. Matsuda, Y. Nakamura, Impact of LIMK1, MMP2 and TNF-alpha variations for intracranial aneurysm in Japanese population. J Hum Genet 56 (2011) 211-216.

[51]V. Kumar, K. Matsuo, A. Takahashi, N. Hosono, T. Tsunoda, N. Kamatani, S.Y. Kong, H. Nakagawa, R. Cui, C. Tanikawa, M. Seto, Y. Morishima, M. Kubo, Y. Nakamura, K. Matsuda, Common variants on 14q32 and 13q12 are associated with DLBCL susceptibility. J Hum Genet56 (2011) 436-439.

[50]V. Kumar, N. Kato, Y. Urabe, A. Takahashi, R. Muroyama, N. Hosono, M. Otsuka, R. Tateishi, M. Omata, H. Nakagawa, K. Koike, N. Kamatani, M. Kubo, Y. Nakamura, K. Matsuda, Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma. Nat Genet 43 (2011) 455-458.

[49]L. Piao, H. Nakagawa, K. Ueda, S. Chung, K. Kashiwaya, H. Eguchi, H. Ohigashi, O. Ishikawa, Y. Daigo, K. Matsuda, Y. Nakamura, C12orf48, termed PARP-1 binding protein, enhances poly(ADP-ribose) polymerase-1 (PARP-1) activity and protects pancreatic cancer cells from DNA damage. Genes, chromosomes & cancer 50 (2011) 13-24.

 [48]Y. Okada, T. Hirota, Y. Kamatani, A. Takahashi, H. Ohmiya, N. Kumasaka, K. Higasa, Y. Yamaguchi-Kabata, N. Hosono, M. Nalls, M. Chen, F. van Rooij, A. Smith, T. Tanaka, D. Couper, N. Zakai, L. Ferrucci, D. Longo, D. Hernandez, J. Witteman, T. Harris, C. O'Donnell, S. Ganesh, K. Matsuda, T. Tsunoda, M. Kubo, Y. Nakamura, M. Tamari, K. Yamamoto, N. Kamatani, Identification of Nine Novel Loci Associated with White Blood Cell Subtypes in a Japanese Population. PLoS genetics 7 (2011) e1002067

[47]Y.J. Kim, M.J. Go, C. Hu, C.B. Hong, Y.K. Kim, J.Y. Lee, J.Y. Hwang, J.H. Oh, D.J. Kim, N.H. Kim, S. Kim, E.J. Hong, J.H. Kim, H. Min, Y. Kim, R. Zhang, W. Jia, Y. Okada, A. Takahashi, M. Kubo, T. Tanaka, N. Kamatani, K. Matsuda, T. Park, B. Oh, K. Kimm, D. Kang, C. Shin, N.H. Cho, H.L. Kim, B.G. Han, Y.S. Cho, Large-scale genome-wide association studies in east Asians identify new genetic loci influencing metabolic traits. Nat Genet 43 (2011) 990-995.

[46]S. Chung, H. Nakagawa, M. Uemura, L. Piao, K. Ashikawa, N. Hosono, R. Takata, S. Akamatsu, T. Kawaguchi, T. Morizono, T. Tsunoda, Y. Daigo, K. Matsuda, N. Kamatani, Y. Nakamura, M. Kubo, Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibility. Cancer science 102 (2011) 245-252.

[45]Y. Okada, A. Takahashi, H. Ohmiya, N. Kumasaka, Y. Kamatani, N. Hosono, T. Tsunoda, K. Matsuda, T. Tanaka, M. Kubo, Y. Nakamura, K. Yamamoto, N. Kamatani, Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus. Human molecular genetics 20 (2011) 1224-1231.

[44]R. Cui, Y. Okada, S.G. Jang, J.L. Ku, J.G. Park, Y. Kamatani, N. Hosono, T. Tsunoda, V. Kumar, C. Tanikawa, N. Kamatani, R. Yamada, M. Kubo, Y. Nakamura, K. Matsuda, Common variant in 6q26-q27 is associated with distal colon cancer in an Asian population. Gut 60 (2011) 799-805.

 [43]A. Toyama, H. Nakagawa, K. Matsuda, N. Ishikawa, N. Kohno, Y. Daigo, T.A. Sato, Y. Nakamura, K. Ueda, Deglycosylation and label-free quantitative LC-MALDI MS applied to efficient serum biomarker discovery of lung cancer. Proteome science 9 (2011) 18.

[42]T. Tanabe, N. Yamaguchi, K. Matsuda, K. Yamazaki, S. Takahashi, A. Tojo, M. Onizuka, Y. Eishi, H. Akiyama, J. Ishikawa, T. Mori, M. Hara, K. Koike, K. Kawa, T. Kawase, Y. Morishima, H. Amano, M. Kobayashi-Miura, T. Kakamu, Y. Nakamura, S. Asano, Y. Fujita, Association analysis of the NOD2 gene with susceptibility to graft-versus-host disease in a Japanese population. International journal of hematology 93 (2011) 771-778.

[41]M.A. Nalls, D.J. Couper, T. Tanaka, F.J. van Rooij, M.H. Chen, A.V. Smith, D. Toniolo, N.A. Zakai, Q. Yang, A. Greinacher, A.R. Wood, M. Garcia, P. Gasparini, Y. Liu, T. Lumley, A.R. Folsom, A.P. Reiner, C. Gieger, V. Lagou, J.F. Felix, H. Volzke, N.A. Gouskova, A. Biffi, A. Doring, U. Volker, S. Chong, K.L. Wiggins, A. Rendon, A. Dehghan, M. Moore, K. Taylor, J.G. Wilson, G. Lettre, A. Hofman, J.C. Bis, N. Pirastu, C.S. Fox, C. Meisinger, J. Sambrook, S. Arepalli, M. Nauck, H. Prokisch, J. Stephens, N.L. Glazer, L.A. Cupples, Y. Okada, A. Takahashi, Y. Kamatani, K. Matsuda, T. Tsunoda, M. Kubo, Y. Nakamura, K. Yamamoto, N. Kamatani, M. Stumvoll, A. Tonjes, I. Prokopenko, T. Illig, K.V. Patel, S.F. Garner, B. Kuhnel, M. Mangino, B.A. Oostra, S.L. Thein, J. Coresh, H.E. Wichmann, S. Menzel, J. Lin, G. Pistis, A.G. Uitterlinden, T.D. Spector, A. Teumer, G. Eiriksdottir, V. Gudnason, S. Bandinelli, T.M. Frayling, A. Chakravarti, C.M. van Duijn, D. Melzer, W.H. Ouwehand, D. Levy, E. Boerwinkle, A.B. Singleton, D.G. Hernandez, D.L. Longo, N. Soranzo, J.C. Witteman, B.M. Psaty, L. Ferrucci, T.B. Harris, C.J. O'Donnell, S.K. Ganesh, Multiple loci are associated with white blood cell phenotypes. PLoS Genet 7 (2011) e1002113.

[40]J. Li, D. Yang, Y. He, M. Wang, Z. Wen, L. Liu, J. Yao, K. Matsuda, Y. Nakamura, J. Yu, X. Jiang, S. Sun, Q. Liu, Q. Song, M. Chen, H. Yang, F. Tang, X. Hu, J. Wang, Y. Chang, X. He, Y. Chen, J. Lin, Associations of HLA-DP variants with hepatitis B virus infection in southern and northern Han Chinese populations: a multicenter case-control study. PloS one 6 (2011) e24221.

2010

[39]C. Tanikawa, C. Ri, V. Kumar, Y. Nakamura, K. Matsuda, Crosstalk of EDA-A2/XEDAR in the p53 signaling pathway. Molecular Cancer Research 8 (2010) 855-863.

[38]Y. Kamatani, K. Matsuda, Y. Okada, M. Kubo, N. Hosono, Y. Daigo, Y. Nakamura, N. Kamatani, Genome-wide association study of hematological and biochemical traits in a Japanese population. Nat Genet 42 (2010) 210-215.

[37]I.P. Tomlinson, M. Dunlop, H. Campbell, B. Zanke, S. Gallinger, T. Hudson, T. Koessler, P.D. Pharoah, I. Niittymakix, S. Tuupanenx, L.A. Aaltonen, K. Hemminki, A. Lindblom, A. Forsti, O. Sieber, L. Lipton, T. van Wezel, H. Morreau, J.T. Wijnen, P. Devilee, K. Matsuda, Y. Nakamura, S. Castellvi-Bel, C. Ruiz-Ponte, A. Castells, A. Carracedo, J.W. Ho, P. Sham, R.M. Hofstra, P. Vodicka, H. Brenner, J. Hampe, C. Schafmayer, J. Tepel, S. Schreiber, H. Volzke, M.M. Lerch, C.A. Schmidt, S. Buch, V. Moreno, C.M. Villanueva, P. Peterlongo, P. Radice, M.M. Echeverry, A. Velez, L. Carvajal-Carmona, R. Scott, S. Penegar, P. Broderick, A. Tenesa, R.S. Houlston, COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer. Br J Cancer 102 (2010) 447-454.

[36]A.K. Maiti, X. Kim-Howard, P. Viswanathan, L. Guillén, X. Qian, A. Rojas-Villarraga, C. Sun, C. Cañas, G.J. Tobón, K. Matsuda, N. Shen, A.C. Cherñavsky, J.M. Anaya, S.K. Nath, Non-synonymous variant (Gly307Ser) in CD226 is associated with susceptibility to multiple autoimmune diseases. Rheumatology (Oxford) 49 (2010) 1239-1244.

[35]Y. Okada, Y. Kamatani, A. Takahashi, K. Matsuda, N. Hosono, H. Ohmiya, Y. Daigo, K. Yamamoto, M. Kubo, Y. Nakamura, N. Kamatani, Common variations in PSMD3-CSF3 and PLCB4 are associated with neutrophil count. Hum Mol Genet 19 (2010) 2079-2085.

[34]Y. Okada, Y. Kamatani, A. Takahashi, K. Matsuda, N. Hosono, H. Ohmiya, Y. Daigo, K. Yamamoto, M. Kubo, Y. Nakamura, N. Kamatani, A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci. Hum Mol Genet 19 (2010) 2303-2312. 

2009

[33]C. Tanikawa, K. Ueda, H. Nakagawa, N. Yoshida, Y. Nakamura, K. Matsuda, Regulation of protein Citrullination through p53/PADI4 network in DNA damage response. Cancer Res 69 (2009) 8761-8769.

[32]S. Han, X. Kim-Howard, H. Deshmukh, Y. Kamatani, P. Viswanathan, J.M. Guthridge, K. Thomas, K.M. Kaufman, J. Ojwang, A. Rojas-Villarraga, V. Baca, L. Orozco, B. Rhodes, C.B. Choi, P.K. Gregersen, J.T. Merrill, J.A. James, P.M. Gaffney, K.L. Moser, C.O. Jacob, R.P. Kimberly, J.B. Harley, S.C. Bae, J.M. Anaya, M.E. Alarcón-Riquelme, K. Matsuda, T.J. Vyse, S.K. Nath, Evaluation of imputation-based association in and around the integrin-alpha-M (ITGAM) gene and replication of robust association between a non-synonymous functional variant within ITGAM and systemic lupus erythematosus (SLE). Human molecular genetics 18 (2009) 1171-1180.

[31]Y. Kamatani, S. Wattanapokayakit, H. Ochi, T. Kawaguchi, A. Takahashi, N. Hosono, M. Kubo, T. Tsunoda, N. Kamatani, H. Kumada, A. Puseenam, T. Sura, Y. Daigo, K. Chayama, W. Chantratita, Y. Nakamura, K. Matsuda, A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians. Nat Genet 41 (2009) 591-595.

 

[30]K. Morioka, C. Tanikawa, K. Ochi, Y. Daigo, T. Katagiri, H. Kawano, H. Kawaguchi, A. Myoui, H. Yoshikawa, N. Naka, N. Araki, I. Kudawara, M. Ieguchi, K. Nakamura, Y. Nakamura, K. Matsuda, Orphan receptor tyrosine kinase ROR2 as a potential therapeutic target for osteosarcoma. Cancer Sci 100 (2009) 1227-1233.

[29]C. Tanikawa, Y. Furukawa, N. Yoshida, H. Arakawa, Y. Nakamura, K. Matsuda, XEDAR as a putative colorectal tumor suppressor that mediates p53-regulated anoikis pathway. Oncogene28 (2009) 3081-3092.

[28]R. Cui, Y. Kamatani, A. Takahashi, M. Usami, N. Hosono, T. Kawaguchi, T. Tsunoda, N. Kamatani, M. Kubo, Y. Nakamura, K. Matsuda, Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk. Gastroenterology 137 (2009) 1768-1775.

2008

[27]C. Okuma, T. Kaketa, A. Hikita, K. Matsuda, M. Nakamura, Y. Nagase, Y. Oshima, M. Iwasawa, Y. Nakamura, H. Kurosawa, K. Nakamura, S. Tanaka, Potential involvement of p53 in ischemia/reperfusion-induced osteonecrosis. Journal of bone and mineral metabolism 26 (2008) 576-585.

[26]Y. Kamatani, K. Matsuda, T. Ohishi, S. Ohtsubo, K. Yamazaki, A. Iida, N. Hosono, M. Kubo, W. Yumura, K. Nitta, T. Katagiri, Y. Kawaguchi, N. Kamatani, Y. Nakamura, Identification of a significant association of a single nucleotide polymorphism in TNXB with systemic lupus erythematosus in a Japanese population. J Hum Genet 53 (2008) 64-73.

[25]T. Oishi, A. Iida, S. Otsubo, Y. Kamatani, M. Usami, T. Takei, K. Uchida, K. Tsuchiya, S. Saito, Y. Ohnisi, K. Tokunaga, K. Nitta, Y. Kawaguchi, N. Kamatani, Y. Kochi, K. Shimane, K. Yamamoto, Y. Nakamura, W. Yumura, K. Matsuda, A functional SNP in the NKX2.5-binding site of ITPR3 promoter is associated with susceptibility to systemic lupus erythematosus in Japanese population. J Hum Genet 53 (2008) 151-162.

[24]T. Kidokoro, C. Tanikawa, Y. Furukawa, T. Katagiri, Y. Nakamura, K. Matsuda, CDC20, a potential cancer therapeutic target, is negatively regulated by p53. Oncogene 27 (2008) 1562-1571.

[23]A. Shimo, C. Tanikawa, T. Nishidate, M.L. Lin, K. Matsuda, J.H. Park, T. Ueki, T. Ohta, K. Hirata, M. Fukuda, Y. Nakamura, T. Katagiri, Involvement of kinesin family member 2C/mitotic centromere-associated kinesin overexpression in mammary carcinogenesis. Cancer Sci 99 (2008) 62-70.

[22]A. Tenesa, S.M. Farrington, J.G. Prendergast, M.E. Porteous, M. Walker, N. Haq, R.A. Barnetson, E. Theodoratou, R. Cetnarskyj, N. Cartwright, C. Semple, A.J. Clark, F.J. Reid, L.A. Smith, K. Kavoussanakis, T. Koessler, P.D. Pharoah, S. Buch, C. Schafmayer, J. Tepel, S. Schreiber, H. Volzke, C.O. Schmidt, J. Hampe, J. Chang-Claude, M. Hoffmeister, H. Brenner, S. Wilkening, F. Canzian, G. Capella, V. Moreno, I.J. Deary, J.M. Starr, I.P. Tomlinson, Z. Kemp, K. Howarth, L. Carvajal-Carmona, E. Webb, P. Broderick, J. Vijayakrishnan, R.S. Houlston, G. Rennert, D. Ballinger, L. Rozek, S.B. Gruber, K. Matsuda, T. Kidokoro, Y. Nakamura, B.W. Zanke, C.M. Greenwood, J. Rangrej, R. Kustra, A. Montpetit, T.J. Hudson, S. Gallinger, H. Campbell, M.G. Dunlop, Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. Nat Genet 40 (2008) 631-637.

[21]A. Suzuki, R. Yamada, Y. Kochi, T. Sawada, Y. Okada, K. Matsuda, Y. Kamatani, M. Mori, K. Shimane, Y. Hirabayashi, A. Takahashi, T. Tsunoda, A. Miyatake, M. Kubo, N. Kamatani, Y. Nakamura, K. Yamamoto, Functional SNPs in CD244 increase the risk of rheumatoid arthritis in a Japanese population. Nat Genet 40 (2008) 1224-1229. 

2007

[20]M. Hosokawa, A. Takehara, K. Matsuda, H. Eguchi, H. Ohigashi, O. Ishikawa, Y. Shinomura, K. Imai, Y. Nakamura, H. Nakagawa, Oncogenic role of KIAA0101 interacting with proliferating cell nuclear antigen in pancreatic cancer. Cancer Res 67 (2007) 2568-2576.

[19]M. Kubo, J. Hata, T. Ninomiya, K. Matsuda, K. Yonemoto, T. Nakano, T. Matsushita, K. Yamazaki, Y. Ohnishi, S. Saito, T. Kitazono, S. Ibayashi, K. Sueishi, M. Iida, Y. Nakamura, Y. Kiyohara, A nonsynonymous SNP in PRKCH (protein kinase C eta) increases the risk of cerebral infarction. Nat Genet 39 (2007) 212-217.

[18]J. Hata, K. Matsuda, T. Ninomiya, K. Yonemoto, T. Matsushita, Y. Ohnishi, S. Saito, T. Kitazono, S. Ibayashi, M. Iida, Y. Kiyohara, Y. Nakamura, M. Kubo, Functional SNP in an Sp1-binding site of AGTRL1 gene is associated with susceptibility to brain infarction. Hum Mol Genet 16 (2007) 630-639.

2000-2004

[17]X. Yang, K. Matsuda, P. Bialek, S. Jacquot, H.C. Masuoka, T. Schinke, L. Li, S. Brancorsini, P. Sassone-Corsi, T.M. Townes, A. Hanauer, G. Karsenty, ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome. Cell 117 (2004) 387-398.

[16]R.B. Vega, K. Matsuda, J. Oh, A.C. Barbosa, X.L. Yang, E. Meadows, J. McAnally, C. Pomajzl, J.M. Shelton, J.A. Richardson, G. Karsenty, E.N. Olson, Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis. Cell 119 (2004) 555-566.

[15]M. Saegusa, M. Murakami, Y. Nakatani, K. Yamakawa, M. Katagiri, K. Matsuda, K. Nakamura, I. Kudo, H. Kawaguchi, Contribution of membrane-associated prostaglandin E-2 synthase to bone resorption. J Cell Physiol 197 (2003) 348-356.

[14]C. Tanikawa, K. Matsuda, S. Fukuda, Y. Nakamura, H. Arakawa, p53RDL1 regulates p53-dependent apoptosis. Nature cell biology 5 (2003) 216-223..

[13]T. Goto, S. Yokokura, H. Kawano, A. Yamamoto, K. Matsuda, K. Nakamura, Simple curettage without bone grafting for enchondromata of the hand: with special reference to replacement of the cortical window. J Hand Surg Br 27 (2002) 446-451.

[12]T. Goto, T. Kojima, T. Iijima, S. Yokokura, T. Motoi, H. Kawano, A. Yamamoto, K. Matsuda, Intraosseous lipoma: a clinical study of 12 patients. J Orthop Sci 7 (2002) 274-280.

[11]T. Goto, T. Ishida, N. Motoi, S. Yokokura, H. Kawano, A. Yamamoto, K. Matsuda, M. Yamamoto, Primary leiomyosarcoma of the femur. J Orthop Sci 7 (2002) 267-273.

[10]K. Matsuda, K. Yoshida, Y. Taya, K. Nakamura, Y. Nakamura, H. Arakawa, p53AIP1 regulates the mitochondrial apoptotic pathway. Cancer Res 62 (2002) 2883-2889.

[9]K. Inoue, K. Matsuda, M. Itoh, H. Kawaguchi, H. Tomoike, T. Aoyagi, R. Nagai, M. Hori, Y. Nakamura, T. Tanaka, Osteopenia and male-specific sudden cardiac death in mice lacking a zinc transporter gene, Znt5. Hum Mol Genet 11 (2002) 1775-1784.

[8]T. Goto, T. Kojima, T. Iijima, S. Yokokura, H. Kawano, A. Yamamoto, K. Matsuda, Soft-tissue haemangioma and periosteal new bone formation on the neighbouring bone. Arch Orthop Trauma Surg 121 (2001) 549-553.

[7]T. Goto, T. Kojima, T. Iijima, S. Yokokura, H. Kawano, A. Yamamoto, K. Matsuda, Resorption of synthetic porous hydroxyapatite and replacement by newly formed bone. J Orthop Sci 6 (2001) 444-447.

[6]T. Goto, T. Kojima, T. Iijima, S. Yokokura, H. Kawano, A. Yamamoto, K. Matsuda, Osteofibrous dysplasia of the ulna. J Orthop Sci 6 (2001) 608-611.

[5]T. Goto, T. Iijima, H. Kawano, A. Yamamoto, M. Arai, K. Matsuda, S. Yokokura, Serum acid phosphatase as a tumour marker in giant cell tumour of bone. Arch Orthop Trauma Surg 121 (2001) 411-413.

[4]T. Yamaguchi, K. Matsuda, Y. Sagiya, M. Iwadate, M.A. Fujino, Y. Nakamura, H. Arakawa, p53R2-dependent pathway for DNA synthesis in a p53-regulated cell cycle checkpoint. Cancer Res 61 (2001) 8256-8262.

[3]M. Futamura, H. Arakawa, K. Matsuda, T. Katagiri, S. Saji, Y. Miki, Y. Nakamura, Potential role of BRCA2 in a mitotic checkpoint after phosphorylation by hBUBR1. Cancer Res 60 (2000) 1531-1535.

[2]K. Shiraishi, S. Fukuda, T. Mori, K. Matsuda, T. Yamaguchi, C. Tanikawa, M. Ogawa, Y. Nakamura, H. Arakawa, Identification of fractalkine, a CX3C-type chemokine, as a direct target of p53. Cancer Res 60 (2000) 3722-3726.

[1]K. Oda, H. Arakawa, T. Tanaka, K. Matsuda, C. Tanikawa, T. Mori, H. Nishimori, K. Tamai, T. Tokino, Y. Nakamura, Y. Taya, p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53. Cell 102 (2000) 849-862.

【日本語総説】

肝癌発生の遺伝的背景:GWAS Analysisから

Author:松田浩一(東京大学医科学研究所シークエンス技術開発分野)

Source:肝・胆・膵 6512 Page971-978 (2012.12)

 HBV持続感染のゲノムワイド関連解析

Author:松田浩一(東京大学医科学研究所 シークエンス技術開発分野)

Source:肝疾患Review Page (2012.6)

 【ゲノムワイド関連解析からみえてきた消化器疾患】 GWASによる癌オーダーメイド医療の実現に向けて

Author:松田浩一(東京大学医科学研究所シークエンス技術開発分野)

SourceG.I.Research(0918-9408)203 Page229-234(2012.06)

 個別化医療実現に向けたイノベーションと課題 癌における個別化医療の現状と今後の展望

Author:松田浩一(東京大学医科学研究所 シークエンス技術開発分野)

Source:日本体質医学会雑誌(1347-7137)741 Page35-40(2012.02)

個別化医療の実現に向けて HCV陽性肝癌発症関連遺伝子の同定

Author:松田浩一(東京大学医科学研究所 シークエンス技術開発分野)

SourceThe Liver Cancer Journal(1883-9347)33 Page201-206(2011.09)

 【ウイルス肝炎の病態解明と治療の進歩】 ゲノムワイド関連解析による慢性B型肝炎疾患感受性遺伝子の同定

Author:松田浩一(東京大学医科学研究所シークエンス技術開発分野), 中村祐輔

Source:最新医学(0370-8241)659 Page1863-1869(2010.09)

 HLAと疾患 最新トピックス】 アジア人における慢性B型肝炎に関する遺伝子多型

Author:松田浩一(東京大学医科学研究所ゲノムシークエンス解析分野), 中村祐輔

Source:医学のあゆみ(0039-2359)23313 Page1193-1198(2010.06)

 SNPが変える肝胆膵診療】 アジア人における慢性B型肝炎に関する遺伝子多型 HLA-DPA1DPB1

Author:松田浩一(東京大学医科学研究所ヒトゲノム解析センター), 中村祐輔

Source:肝・胆・膵(0389-4991)596 Page1147-1154(2009.12)

 【全ゲノム関連解析と多因子疾患】 各疾患領域における遺伝子解析 大腸癌関連遺伝子の全ゲノム関連解析

Author:松田浩一(東京大学医科学研究所ヒトゲノム解析センター), 中村祐輔

Source:最新医学(0370-8241)644 Page880-886(2009.04)