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(Our Research, Achievement and Activity)

Members of our laboratory are generally divided into the dry team and the wet team. The dry team focus on the clinical epidemiology/pharmacoepidemiology, health policy, and regulatory science researches. The wet team mainly conducts researches on the safety and efficacy of the newly concepted drugs such as hybrid peptide, and drug delivery system (DDS) and microscopic imaging tools for the assessment of drugs and medical devices.

Researchers and students in the dry team conduct studies based on their clinical questions or working experiences. Most of the students has experienced with physician, surgeon, anestheologist, pharmacist, or nurse. We also welcome individuals from pharmaceutical companies conducting R&D, regulatory affairs, and clinical/economical evaluation of the products; health-related industries; and government officers engaged in health or drug policymaking. We fully support students who aim to be distinguished researcher or professional in the field. The keywords for our research area are clinical epidemiology, pharmacoepidemiology, EBM, regulatory science, cost-effectiveness analysis and comparative effectiveness research (CER), health technology assessment (HTA), medical big-data, life course data. We believe our activities and alum will be highly needed from various fields in the near future.

Research in the wet field mainly include studies on anti-cancer drugs created by our invention, the hybrid peptide technique. These research activities, including next-generation drug development, are yielding vibrant studies, which are not limited to theoretical research but also include applied research, which characterizes how medical researchers distinguish themselves from other scientists in pharmacy or bioscience fields.

(Dry team research activity)

  • Research on use of steroids during the perioperative period and postoperative prognosis (clinical epidemiology research)
  • Research on perioperative anesthesia management (clinical epidemiology research)
  • Descriptive epidemiology of the treatment of psychogenetic epilepsia (clinical epidemiology research)
  • Epidemiology of the treatment for stroke prevention for atrial fibrillation patients (pharmacoepidemiology research
  • Various research using maternal and child health big data in Kobe city (epidemiology research)
  • Research on clinical outcomes of treatment for stroke and related costs (health economy research)
  • Research on the cost-effectiveness of breast cancer treatment (pharmaco economy research)
  • Research on the cost-effectiveness of breast cancer screening examinations (health economic research)
  • Epidemiology study of the use and adherence of oral anticoagulants (pharmacoepidemiology research)
  • Research on the use of antipsychotic drugs in Japan (pharmacoepidemiology research)
  • Epidemiology of the colonic disorder diagnosis of patients with positive results in fecal occult blood tests during health examinations (diagnostic epidemiology research)
  • Research on the proper use of analgesics using a large database (pharmacoepidemiology research)
  • Research on neonatal care and prognosis of growth (clinical epidemiology research)
  • Fact-finding research on medication guidance at dispensing pharmacies and the use of oral anti-cancer drugs (pharmacoepidemiology research)
  • Model research on proper drug prices for off-patent original drugs (pharmacoeconomy research)

(Wet team research activity)

  • Development of a new cancer therapy utilizing molecular-targeted hybrid peptide
  • Mechanism of intracellular chaperon molecule and drug discovery
  • Development and evaluation of new mechanical drug delivery system to pancreatic cancer

Ongoing research projects as June 2012