2. Fukuda K, Matsuzaki H, Hiraishi Y, Miyashita N, Ishii T, Yuki M, Isago H, Tamiya H, Mitani A, Saito A, Jo T, Nagase T. Anti-Inflammatory Effects of Japanese Herbal Medicine Hochuekkito in a Mouse Model of Acute Exacerbation of Chronic Obstructive Pulmonary Disease. Pharmacology. 2024;109(2):121-126.

3. Enokido T, Horie M, Yoshino S, Suzuki HI, Matsuki R, Brunnström H, Micke P, Nagase T, Saito A, Miyashita N. Distinct microRNA Signature and Suppression of ZFP36L1 Define ASCL1-Positive Lung Adenocarcinoma. Mol Cancer Res. 2024 Jan 2;22(1):29-40.

4. Yokoyama A, Jo T, Sakamoto Y, Urushiyama H, Tamiya H, Tanaka G, Kumazawa R, Matsui H, Fushimi K, Yasunaga H, Nagase T. Effectiveness and safety of the co- administration of Yokukan-San (Japanese herbal medicine) with antipsychotics in hospitalized older patients with pneumonia. Geriatr Gerontol Int. 2023 Nov;23(11):849-854. doi: 10.1111/ggi.14696. Epub 2023 Oct 7.

5. Konkimalla A, Konishi S, Macadlo L, Kobayashi Y, Farino ZJ, Miyashita N, El Haddad L, Morowitz J, Barkauskas CE, Agarwal P, Souma T, ElMallah MK, Tata A, Tata PR. Transitional cell states sculpt tissue topology during lung regeneration. Cell Stem Cell. 2023 Nov 2;30(11):1486-1502.e9.

6. Awano N, Jo T, Izumo T, Inomata M, Ito Y, Morita K, Matsui H, Fushimi K, Urushiyama H, Nagase T, Yasunaga H. Polymyxin B-immobilised fibre column treatment for acute exacerbation of idiopathic pulmonary fibrosis patients with mechanical ventilation: a nationwide observational study. J Intensive Care. 2023 Oct 11;11(1):45. doi: 10.1186/s40560-023-00693-0.

7. Awano N, Jo T, Izumo T, Inomata M, Ito Y, Hashimoto Y, Matsui H, Fushimi K, Urushiyama H, Nagase T, Yasunaga H. Hospital volume and outcomes following bronchoscopy in patients with interstitial lung disease: A retrospective observational study using a national inpatient database in Japan. Respir Investig. 2023 Nov;61(6):720-728. doi: 10.1016/j.resinv.2023.07.005. Epub 2023 Sep 13.

8. Jo T, Shigemi D, Konishi T, Yamana H, Michihata N, Kumazawa R, Yokoyama A, Urushiyama H, Matsui H, Fushimi K, Nagase T, Yasunaga H. Antiemetic Effect of Rikkunshito, a Japanese Kampo Herbal Medicine, on Cisplatin-induced Nausea and Vomiting: A Nationwide Database Study in Japan. Intern Med. 2024 Apr 1;63(7):919-927. doi: 10.2169/internalmedicine.1946-23. Epub 2023 Jul 26.

9. Yu Mikami, Barbara R Grubb, Troy D Rogers, Hong Dang, Takanori Asakura, Pradeep Kota, Rodney C Gilmore, Kenichi Okuda, Lisa C Morton, Ling Sun, Gang Chen, Jason A Wykoff, Camille Ehre, Juan Vilar, Catharina van Heusden, Alessandra Livraghi-Butrico, Martina Gentzsch, Brian Button, M Jackson Stutts, Scott H Randell, Wanda K O'Neal, Richard C Boucher, Chronic airway epithelial hypoxia exacerbates injury in muco-obstructive lung disease through mucus hyperconcentration, Sci Transl Med.023 Jun;15(699):eabo7728.

10. Awano N, Urushiyama H, Yamana H, Yokoyama A, Ando T, Izumo T, Inomata M, Ito Y, Jo T. Validity of diagnoses of respiratory diseases recorded in a Japanese administrative database. Respir Investig. 2023 May;61(3):314-320. doi: 10.1016/j.resinv.2023.01.009. Epub 2023 Mar 1.

11. Horie M, Tanaka H, Suzuki M, Sato Y, Takata S, Takai E, Miyashita N, Saito A, Nakatani Y, Yachida S. An integrative epigenomic approach identifies ELF3 as an oncogenic regulator in ASCL1-positive neuroendocrine carcinoma. Cancer Sci. 2023; Feb 24.doi: 10.1111/cas.15764. Online ahead of print.

12. Urushiyama H, Jo T, Hasegawa W, Yokoyama A, Ando T, Sakamoto Y, Kumazawa R, Uda K, Michihata N, Awano N, Hiroki M, Fushimi K, Yasunaga H, Nagase T. Effect of nintedanib on acute exacerbations of fibrosing interstitial lung diseases: a national database study in Japan. ERJ Open Res. 2022 Nov 28;8(4):00209-2022.

13. Miyakawa K, Miyashita N, Horie M, Terasaki Y, Tanaka H, Urushiyama H, Fukuda K, Okabe Y, Ishii T, Kuwahara N, Suzuki HI, Nagase T, Saito A. ASCL1 regulates super-enhancerassociated miRNAs to define molecular subtypes of small cell lung cancer. Cancer Sci 2022; 113(11): 3932-46.

14. Tian D, Shiiya H, Takahashi M, Terasaki Y, Urushiyama H, Shinozaki-Ushiku A, Yan HJ, Sato M, Nakajima J. Noninvasive monitoring of allograft rejection in a rat lung transplant model: Application of machine learning-based 18F-fluorodeoxyglucose positron emission tomography radiomics. J Heart Lung Transplant. 2022 Jun;41(6):722-731.

15. Awano N, Jo T, Izumo T, Inomata M, Morita K, Matsui H, Fushimi K, Urushiyama H, Nagase T, Yasunaga H. Recombinant human soluble thrombomodulin for acute exacerbation of idiopathic pulmonary fibrosis: a nationwide observational study. J Intensive Care. 2022 Mar 9;10(1):14.

16. Oki R, Hirakawa Y, Oda Y, Nakamura M, Honda K, Abe H, Domoto Y, Miyashita N, Nagase T, Nangaku M. Renal-limited ANCA-associated vasculitis during erlotinib treatment for lung carcinoma. CEN Case Rep 2022; 11: 67-72.

17. Miyashita N, Enokido T, Horie M, Fukuda K, Urushiyama H, Strell C, Brunnström H, Micke P, Saito A, Nagase T. TGF-β-mediated epithelial-mesenchymal transition and tumor-promoting effects in CMT64 cells are reflected in the transcriptomic signature of human lung adenocarcinoma. Sci Rep 2021; 11: 22380.

18. Yamaguchi Y, Saito A, Horie M, Aoki A, Micke P, Ohshima M, Kappert K. Targeting hepatocyte growth factor in epithelial-stromal interactions in an in vitro experimental model of human periodontitis. Odontology. 2021;109(4):912-920.

19. Miyashita N, Saito A. Organ Specificity and Heterogeneity of Cancer-Associated Fibroblasts in Colorectal Cancer. Int J Mol Sci 2021; 22.

20. Ishii T, Murakami Y, Narita T, Nunokawa H, Miyake K, Nagase T, Yamashita N. Myeloid differentiation protein-2 has a protective role in house dust mite-mediated asthmatic characteristics with the proinflammatory regulation of airway epithelial cells and dendritic cells. Clin Exp Allergy 2021.

21. Urushiyama H, Jo T, Hasegawa W, Ando T, Sakamoto Y, Uda K, Matsui H, Fushimi K, Yasunaga H, Nagase T. Preoperative use of pirfenidone and reduced risk of postoperative severe respiratory complications in patients with idiopathic pulmonary fibrosis: Propensity score-matched analysis using a nationwide database in Japan. Respirology 2021; 26: 590-596.

22. Huang N, Pérez P, Kato T, Mikami Y, Okuda K, Gilmore RC, Conde CD, Gasmi B, Stein S, Beach M, Pelayo E, Maldonado JO, Lafont BA, Jang SI, Nasir N, Padilla RJ, Murrah VA, Maile R, Lovell W, Wallet SM, Bowman NM, Meinig SL, Wolfgang MC, Choudhury SN, Novotny M, Aevermann BD, Scheuermann RH, Cannon G, Anderson CW, Lee RE, Marchesan JT, Bush M, Freire M, Kimple AJ, Herr DL, Rabin J, Grazioli A, Das S, French BN, Pranzatelli T, Chiorini JA, Kleiner DE, Pittaluga S, Hewitt SM, Burbelo PD, Chertow D, Frank K, Lee J, Boucher RC, Teichmann SA, Warner BM, Byrd KM. SARS-CoV-2 infection of the oral cavity and saliva. Nat Med 2021; 27: 892-903.

23. Fukuda K, Matsuzaki H, Mikami Y, Makita K, Miyakawa K, Miyashita N, Hosoki K, Ishii T, Noguchi S, Urushiyama H, Horie M, Mitani A, Yamauchi Y, Shimura E, Nakae S, Saito A, Nagase T, Hiraishi Y. A mouse model of asthma-chronic obstructive pulmonary disease overlap induced by intratracheal papain. Allergy 2021; 76: 390-394.

24. Okuda R, Takemura T, Mikami Y et al. Inhalation challenge test using pigeon eggs for chronic hypersensitivity pneumonitis. Clin Exp Allergy. 2020 Dec;50(12):1381-1390.

25. Miyashita N, Horie M, Suzuki HI, Saito M, Mikami Y, Okuda K, Boucher RC, Suzukawa M, Hebisawa A, Saito A, Nagase T. FOXL1 Regulates Lung Fibroblast Function via Multiple Mechanisms. Am J Respir Cell Mol Biol. 2020 Dec;63(6):831-842.

26. Hosoki K, Mikami Y, Urushiyama H, Souma K, Kawamura G, Uchida K, Nagase T, Jo T. Predictors of postoperative acute exacerbation of interstitial lung disease: a case-control study. BMJ Open Respir Res. 2020 Oct;7(1):e000634.

27. Miyashita N, Horie M, Mikami Y, Urushiyama H, Fukuda K, Miyakawa K, Matsuzaki H, Makita K, Morishita Y, Harada H, Backman M, Lindskog C, Brunnstrom H, Micke P, Nagase T, Saito A. ASCL1 promotes tumor progression through cell-autonomous signaling and immune modulation in a subset of lung adenocarcinoma. Cancer Lett. 2020 Jun 10;S0304-3835(20)30304-9.

28. Saito M, Mitani A, Ishimori T, Miyashita N, Isago H, Mikami Y, Noguchi S, Tarui M, Nagase T. Active mTOR in Lung Epithelium Promotes Epithelial-Mesenchymal Transition and Enhances Lung Fibrosis. Am J Respir Cell Mol Biol 2020; 62: 699-708.

29. Okunishi K, Wang H, Suzukawa M, Ishizaki R, Kobayashi E, Kihara M, Abe T, Miyazaki J, Horie M, Saito A, Saito H, Nakae S, Izumi T. Exophilin-5 regulates allergic airway inflammation by controlling IL-33-mediated Th2 responses. J Clin Invest. 2020 Jun 8;127839.

30. Ishii T, Muroi M, Horiguchi K, Tanamoto KI, Nagase T, Yamashita N. Activation through toll-like receptor 2 on group 2 innate lymphoid cells can induce asthmatic characteristics. Clin Exp Allergy. 2019 Dec;49(12):1624–1632.

31. Mikami Y, Jo T, Matsuzaki H et al. Preoperative intervention with long-acting bronchodilators for the reduction of postoperative pulmonary complications in untreated patients with obstructive lung disease. Clin Respir J. 2019 Nov 12. doi: 10.1111/crj.13105.

32. Saito A, Hakamata Y, Yamada Y, Sunohara M, Tarui M, Murano Y, Mitani A, Tanaka K, Nagase T, Yanagimoto S. Pleural thickening on screening chest X-rays: a single institutional study. Respir Res. 2019 Jul 5;20(1):138.

33. Urushiyama H, Terasaki Y, Nagasaka S et al. Naftopidil reduced the proliferation of lung fibroblasts and bleomycin-induced lung fibrosis in mice. J Cell Mol Med. 2019 May;23(5):3563-3571.

34. Hiraishi Y, Yamaguchi S, Yoshizaki T et al. IL-33, IL-25 and TSLP contribute to development of fungal- associated protease-induced innate-type airway inflammation. Sci Rep. 2018 Dec 21;8(1):18052.

35. Saito A, Horie M, Micke P, Nagase T. The Role of TGF-β Signaling in Lung Cancer Associated with Idiopathic Pulmonary Fibrosis. Int J Mol Sci. 2018;19(11). Epub 2018/11/15.

36. Noguchi S, Saito A, Nagase T. YAP/TAZ Signaling as a Molecular Link between Fibrosis and Cancer.Int J Mol Sci. 2018 Nov 20;19(11). pii: E3674. doi: 10.3390/ijms19113674. Review.PMID: 30463366

37. Hiraishi Y, Izumo T, Sasada S, Matsumoto Y, Nakai T, Tsuchida T, Baba H.Factors affecting bacterial culture positivity in specimens from bronchoscopy in patients with suspected lung cancer.Respir Investig. 2018 Nov;56(6):457-463. doi: 10.1016/j.resinv.2018.07.006. Epub 2018 Oct 24.

38. Yokoyama A, Kage H, Ohama Y, Sato T, Miyashita N, Noguchi S, Okugawa S, Yamauchi Y, Moriya K, Nagase T. Mycobacterium heckeshornense lung infection diagnosed by matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS). J Infect Chemother 2018; 24: 763-765.

39. Antonio VAA, Ono N, Saito A, Sato T, Altaf-Ul-Amin M, Kanaya S. Classification of lung adenocarcinoma transcriptome subtypes from pathological images using deep convolutional networks. Int J Comput Assist Radiol Surg. 2018;13(12):1905-13. Epub 2018/8/29.

40. Hiraishi Y, Jo T, Michihata N, Hasegawa W, Sakamoto Y, Urushiyama H, Matsui H, Fushimi K, Nagase T, Yasunaga H, Yamauchi Y. Hospital Volume and Mortality following Diagnostic Bronchoscopy in Lung Cancer Patients: Data from a National Inpatient Database in Japan. Respiration. 2018 Nov 8:1-9. doi: 10.1159/000493859.

41. Takeshima H, Horie M, Mikami Y, Makita K, Miyashita N, Matsuzaki H, Noguchi S, Urushiyama H, Hiraishi Y, Mitani A, Borok Z, Nagase T, Yamauchi Y. CISH is a negative regulator of IL-13-induced CCL26 production in lung fibroblasts. Allergol Int. 2018 Sep 6. pii: S1323-8930(18)30102-3. doi: 10.1016/j.alit.2018.08.005.

42. Urushiyama H, Jo T, Yasunaga H et al. Oral fluorouracil vs vinorelbine plus cisplatin as adjuvant chemotherapy for stage II-IIIA non-small cell lung cancer: Propensity score-matched and instrumental variable analyses. Cancer Med. 2018 Oct;7(10):4863-4869.

43. Saito A, Horie M, Nagase T. TGF-β Signaling in Lung Health and Disease. Int J Mol Sci. 2018;19(8). Epub 2018/8/20.

44. Miyashita N, Horie M, Suzuki HI, Yoshihara M, Djureinovic D, Persson J, et al. An Integrative Analysis of Transcriptome and Epigenome Features of ASCL1-Positive Lung Adenocarcinomas. J Thorac Oncol. 2018;13(11):1676-91.

45. Souma K, Shichino S, Hashimoto S, et al. Lung fibroblasts express a miR-19a-19b-20a sub-cluster to suppress TGF-beta-associated fibroblast activation in murine pulmonary fibrosis. Sci Rep. 2018;8(1):16642

46. Urushiyama H, Jo T, Yasunaga H et al. Effect of Hangeshashin-To (Japanese Herbal Medicine Tj-14) on Tolerability of Irinotecan: Propensity Score and Instrumental Variable Analyses. J Clin Med. 2018 Aug 28;7(9).

47. Horie M, Miyashita N, Mattsson JSM, Mikami Y, Sandelin M, Brunnstrom H, et al. An integrative transcriptome analysis reveals a functional role for thyroid transcription factor-1 in small cell lung cancer. The Journal of pathology. 2018. Epub 2018/06/08.

48. Ishii T, Nikura Y, Kurata K, Muroi M, Tanamoto K, Nagase T, Sakaguchi M, Yamashita N. Time-dependent distinct roles of Toll-like receptor 4 in a house dust mite-induced asthma mouse model. Scand J Immunol. 2018 Mar;87(3).

49. Makita K, Mikami Y, Matsuzaki H, Miyashita N, Takeshima H, Noguchi S, et al. Mechanism of Periostin Production in Human Bronchial Smooth Muscle Cells. International archives of allergy and immunology. 2018;175(1-2):26-35. Epub 2018/01/18.

50. Horie M, Miyashita N, Mikami Y, Noguchi S, Yamauchi Y, Suzukawa M, et al. TBX4 is involved in the super-enhancer-driven transcriptional programs underlying features specific to lung fibroblasts. American journal of physiology Lung cellular and molecular physiology. 2018;314(1):L177-L91. Epub 2017/10/04.

51. Makita K, Mikami Y, Matsuzaki H, Narumoto O, Takai D, Yatomi Y, et al. Utility of bronchoscopy in the definitive diagnosis of patients with haematological malignancies presenting with radiological abnormalities. The clinical respiratory journal. 2018;12(4):1381-8. Epub 2017/07/29.

52. Urushiyama H, Jo T, Yasunaga H, Yamauchi Y, Matsui H, Hasegawa W, et al. Adjuvant chemotherapy versus chemoradiotherapy for small cell lung cancer with lymph node metastasis: a retrospective observational study with use of a national database in Japan. BMC cancer. 2017;17(1):613. Epub 2017/09/04.

53. Hasegawa W, Yamauchi Y, Yasunaga H, Takeshima H, Sakamoto Y, Jo T, et al. Prognostic nomogram for inpatients with asthma exacerbation. BMC pulmonary medicine. 2017;17(1):108. Epub 2017/08/06.

54. Horie M, Kaczkowski B, Ohshima M, Matsuzaki H, Noguchi S, Mikami Y, et al. Integrative CAGE and DNA Methylation Profiling Identify Epigenetically Regulated Genes in NSCLC. Molecular cancer research : MCR. 2017;15(10):1354-65. Epub 2017/07/13.

55. Saito A, Horie M, Ejiri K, Aoki A, Katagiri S, Maekawa S, et al. MicroRNA profiling in gingival crevicular fluid of periodontitis-a pilot study. FEBS Open Bio. 2017;7(7):981-94. Epub 2017/7/5.

56. Ishii T, Hosoki K, Nikura Y, Yamashita N, Nagase T, Yamashita N. IFN Regulatory Factor 3 Potentiates Emphysematous Aggravation by Lipopolysaccharide. Journal of immunology. 2017;198(9):3637-49. Epub 2017/04/02.

57. Suzuki HI, Katsura A, Mihira H, Horie M, Saito A, Miyazono K. Regulation of TGF-beta-mediated endothelial-mesenchymal transition by microRNA-27. Journal of biochemistry. 2017. Epub 2017/03/25.

58. Noguchi S, Saito A, Mikami Y, Urushiyama H, Horie M, Matsuzaki H, et al. TAZ contributes to pulmonary fibrosis by activating profibrotic functions of lung fibroblasts. Scientific reports. 2017;7:42595. Epub 2017/02/15.

59. Yamauchi Y, Yasunaga H, Sakamoto Y, Hasegawa W, Takeshima H, Urushiyama H, et al. Mortality associated with bone fractures in COPD patients. International journal of chronic obstructive pulmonary disease. 2016;11:2335-40. Epub 2016/10/06.

60. Djureinovic D, Hallstrom BM, Horie M, Mattsson JS, La Fleur L, Fagerberg L, et al. Profiling cancer testis antigens in non-small-cell lung cancer. JCI insight. 2016;1(10):e86837. Epub 2016/10/05.

61. Horie M, Yamaguchi Y, Saito A, Nagase T, Lizio M, Itoh M, et al. Transcriptome analysis of periodontitis-associated fibroblasts by CAGE sequencing identified DLX5 and RUNX2 long variant as novel regulators involved in periodontitis. Scientific reports. 2016;6:33666. Epub 2016/09/21.

62. Horie M, Saito A, Ohshima M, Suzuki HI, Nagase T. YAP and TAZ modulate cell phenotype in a subset of small cell lung cancer. Cancer science. 2016. Epub 2016/09/15.

63. Yamauchi Y, Yasunaga H, Hasegawa W, Sakamoto Y, Takeshima H, Jo T, et al. Effect of outpatient therapy with inhaled corticosteroids on decreasing in-hospital mortality from pneumonia in patients with COPD. International journal of chronic obstructive pulmonary disease. 2016;11:1403-11. Epub 2016/07/07.

64. Mikami Y, Matsuzaki H, Takeshima H, Makita K, Yamauchi Y, Nagase T. Development of an In Vitro Assay to Evaluate Contractile Function of Mesenchymal Cells that Underwent Epithelial-Mesenchymal Transition. Journal of visualized experiments : JoVE. 2016(112). Epub 2016/06/25.

65. Hiraishi Y, Nambu A, Shibui A, Nakanishi W, Yamaguchi S, Morita H, et al. TIM-3 is not essential for development of airway inflammation induced by house dust mite antigens. Allergology international : official journal of the Japanese Society of Allergology. 2016;65(4):459-65. Epub 2016/05/23.

66. Kibinge N, Ono N, Horie M, Sato T, Sugiura T, Altaf-Ul-Amin M, et al. Integrated pathway-based transcription regulation network mining and visualization based on gene expression profiles. Journal of biomedical informatics. 2016;61:194-202. Epub 2016/04/12.

67. Ohshima M, Yamaguchi Y, Ambe K, Horie M, Saito A, Nagase T, et al. Fibroblast VEGF- receptor 1 expression as molecular target in periodontitis. J Clin Periodontol. 2016;43(2):128-37. Epub 2016/2/23.

68. Horie M, Tamiya H, Goto Y, Suzuki M, Matsuzaki H, Hasegawa WT, et al. Nonspecific elevation of serum Aspergillus galactomannan antigen levels in patients with rheumatoid arthritis. Respiratory investigation. 2016;54(1):44-9. Epub 2016/01/01.

69. Matsuzaki H, Mikami Y, Makita K, Takeshima H, Horie M, Noguchi S, et al. Interleukin-17A and Toll-Like Receptor 3 Ligand Poly(I:C) Synergistically Induced Neutrophil Chemoattractant Production by Bronchial Epithelial Cells. PloS one. 2015;10(10):e0141746. Epub 2015/10/28.

70. Saito A, Nagase T. Hippo and TGF-beta interplay in the lung field. American journal of physiology Lung cellular and molecular physiology. 2015;309(8):L756-67. Epub 2015/09/01.

71. Yamauchi Y, Yasunaga H, Matsui H, Hasegawa W, Jo T, Takami K, et al. Comparison of clinical characteristics and outcomes between aspiration pneumonia and community-acquired pneumonia in patients with chronic obstructive pulmonary disease. BMC pulmonary medicine. 2015;15:69. Epub 2015/07/15.

72. Ishii T, Goto Y, Matsuzaki H, Ohishi N, Sakamoto Y, Saito R, et al. Pulmonary Metastasis of Combined Hepatocellular and Cholangiocarcinoma: A Unique Radiographic Presentation with Air-space Consolidation Masquerading as Pneumonia and Primary Pulmonary Adenocarcinoma. Intern Med. 2015;54(11):1389-92. Epub 2015/06/02.

73. Urushiyama H, Terasaki Y, Nagasaka S, Terasaki M, Kunugi S, Nagase T, et al. Role of alpha1 and alpha2 chains of type IV collagen in early fibrotic lesions of idiopathic interstitial pneumonias and migration of lung fibroblasts. Laboratory investigation; a journal of technical methods and pathology. 2015;95(8):872-85. Epub 2015/05/26.

74. Yamauchi Y, Yasunaga H, Matsui H, Hasegawa W, Jo T, Takami K, et al. Comparison of in-hospital mortality in patients with COPD, asthma and asthma-COPD overlap exacerbations. Respirology. 2015;20(6):940-6. Epub 2015/05/23.

75. Horie M, Saito A, Yamaguchi Y, Ohshima M, Nagase T. Three-dimensional Co-culture Model for Tumor-stromal Interaction. Journal of visualized experiments : JoVE. 2015(96). Epub 2015/03/06.

76. Hasegawa W, Yamauchi Y, Yasunaga H, Sunohara M, Jo T, Matsui H, et al. Factors that predict in-hospital mortality in eosinophilic granulomatosis with polyangiitis. Allergy. 2015. Epub 2015/02/24.

77. Hasegawa W, Yamauchi Y, Yasunaga H, Sunohara M, Jo T, Matsui H, et al. Clinical features of 280 hospitalized patients with lymphangioleiomyomatosis in Japan. Respirology. 2015;20(1):160-5. Epub 2014/11/12.

78. Yamauchi Y, Hasegawa W, Yasunaga H, Sunohara M, Jo T, Takami K, et al. Paradoxical association between body mass index and in-hospital mortality in elderly patients with chronic obstructive pulmonary disease in Japan. International journal of chronic obstructive pulmonary disease. 2014;9:1337-46. Epub 2014/12/20.

79. Mikami Y, Matsuzaki H, Horie M, Noguchi S, Jo T, Narumoto O, et al. Lymphotoxin beta Receptor Signaling Induces IL-8 Production in Human Bronchial Epithelial Cells. PloS one. 2014;9(12):e114791. Epub 2014/12/17.

80. Hasegawa W, Yamauchi Y, Yasunaga H, Sunohara M, Jo T, Matsui H, et al. Factors affecting mortality following emergency admission for chronic obstructive pulmonary disease. BMC pulmonary medicine. 2014;14(1):151. Epub 2014/09/26.

81. Horie M, Saito A, Noguchi S, Yamaguchi Y, Ohshima M, Morishita Y, et al. Differential knockdown of TGF-beta ligands in a three-dimensional co-culture tumor- stromal interaction model of lung cancer. BMC cancer. 2014;14:580. Epub 2014/08/12.

82. Isogaya K, Koinuma D, Tsutsumi S, Saito RA, Miyazawa K, Aburatani H, et al. A Smad3 and TTF-1/NKX2-1 complex regulates Smad4-independent gene expression. Cell Res. 2014;24(8):994-1008. Epub 2014/7/25.

83. Okazaki H, Ishikawa O, Iijima T, Kohira T, Teranishi M, Kawasaki S, et al. Novel swine model of transfusion-related acute lung injury. Transfusion. 2014. Epub 2014/06/27.

84. Noguchi S, Saito A, Horie M, Mikami Y, Suzuki HI, Morishita Y, et al. An integrative analysis of the tumorigenic role of TAZ in human non-small cell lung cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2014. Epub 2014/06/22.

85. Tarui M, Shindou H, Kumagai K, Morimoto R, Harayama T, Hashidate T, et al. Selective inhibitors of a PAF biosynthetic enzyme lysophosphatidylcholine acyltransferase 2. Journal of lipid research. 2014;55(7):1386-96. Epub 2014/05/23.

86. Horie M, Saito A, Yamauchi Y, Mikami Y, Sakamoto M, Jo T, et al. Histamine induces human lung fibroblast-mediated collagen gel contraction via histamine H1 receptor. Experimental lung research. 2014;40(5):222-36. Epub 2014/05/09.

87. O'Sullivan MJ, Hirota N, Martin JG. Sphingosine 1-phosphate (S1P) induced interleukin-8 (IL-8) release is mediated by S1P receptor 2 and nuclear factor kappaB in BEAS-2B cells. PloS one. 2014;9(4):e95566. Epub 2014/04/20.

88. Hirota N, McCuaig S, O'Sullivan MJ, Martin JG. Serotonin augments smooth muscle differentiation of bone marrow stromal cells. Stem cell research. 2014;12(3):599-609. Epub 2014/03/07.

89. Noguchi S, Yamauchi Y, Takizawa H. Novel therapeutic strategies for fibrotic lung disease: a review with a focus on epithelial-mesenchymal transition. Recent patents on inflammation & allergy drug discovery. 2014;8(1):9-18. Epub 2014/01/05.

90. Hirota N, Martin JG. Mechanisms of airway remodeling. Chest. 2013;144(3):1026-32. Epub 2013/09/07.

91. Narumoto O, Niikura Y, Ishii S, Morihara H, Okashiro S, Nakahari T, et al. Effect of secreted lymphocyte antigen-6/urokinase-type plasminogen activator receptor-related peptide-1 (SLURP-1) on airway epithelial cells. Biochemical and biophysical research communications. 2013;438(1):175-9. Epub 2013/07/24.

92. Saito A. EMT and EndMT: regulated in similar ways? J Biochem. 2013;153(6):493-5. Epub 2013/4/23.

93. Saito A, Suzuki HI, Horie M, Ohshima M, Morishita Y, Abiko Y, et al. An integrated expression profiling reveals target genes of TGF-beta and TNF-alpha possibly mediated by microRNAs in lung cancer cells. PloS one. 2013;8(2):e56587. Epub 2013/02/26.

94. Mikami Y, Yamauchi Y, Horie M, Kase M, Jo T, Takizawa H, et al. Tumor necrosis factor superfamily member LIGHT induces epithelial-mesenchymal transition in A549 human alveolar epithelial cells. Biochemical and biophysical research communications. 2012;428(4):451-7. Epub 2012/11/08.

95. Horie M, Saito A, Mikami Y, Ohshima M, Morishita Y, Nakajima J, et al. Characterization of human lung cancer-associated fibroblasts in three-dimensional in vitro co-culture model. Biochemical and biophysical research communications. 2012;423(1):158-63. Epub 2012/05/29.

96. Yamauchi Y, Kohyama T, Jo T, Nagase T. Dynamic change in respiratory resistance during inspiratory and expiratory phases of tidal breathing in patients with chronic obstructive pulmonary disease. International journal of chronic obstructive pulmonary disease. 2012;7:259-69. Epub 2012/05/17.

97. Narumoto O, Matsuo Y, Sakaguchi M, Shoji S, Yamashita N, Schubert D, et al. Suppressive effects of a pyrazole derivative of curcumin on airway inflammation and remodeling. Experimental and molecular pathology. 2012;93(1):18-25. Epub 2012/05/01.

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