香月 博志教授の業績リスト201111月現在)

 

 英文原著

Ohnishi M, Katsuki H, Fukutomi C, Takahashi M, Motomura M, Fukunaga M, Matsuoka Y, Isohama Y, Izumi Y, Kume T, Inoue A, Akaike A.

HMGB1 inhibitor glycyrrhizin attenuates intracerebral hemorrhage-induced injury in rats.

Neuropharmacology. 2011 Oct-Nov;61(5-6):975-980.

 

Michinaga S, Hisatsune A, Isohama Y, Katsuki H.

Orexin neurons in hypothalamic slice cultures are vulnerable to endoplasmic reticulum stress.

Neuroscience. 2011 Sep 8;190:289-300.

 

Hijioka M, Matsushita H, Hisatsune A, Isohama Y, Katsuki H.

Therapeutic effect of nicotine in a mouse model of intracerebral hemorrhage.

J Pharmacol Exp Ther. 2011 Sep;338(3):741-749.

 

Hisatsune A, Nakayama H, Kawasaki M, Horie I, Miyata T, Isohama Y, Kim KC, Katsuki H.

Anti MUC1 antibody inhibits EGF receptor signaling in cancer cells.

Biochem Biophys Res Commun. 2011 Feb 18;405(3):377-381.

 

Kurauchi Y, Hisatsune A, Isohama Y, Sawa T, Akaike T, Shudo K, Katsuki H.

Midbrain dopaminergic neurons utilize nitric oxide/cyclic GMP signaling to recruit ERK that links retinoic acid receptor stimulation to up-regulation of BDNF.

J Neurochem. 2011 Feb;116(3):323-333.

 

Matsushita H, Hijioka M, Hisatsune A, Isohama Y, Shudo K, Katsuki H.

A retinoic acid receptor agonist Am80 rescues neurons, attenuates inflammatory reactions, and improves behavioral recovery after intracerebral hemorrhage in mice.

J Cereb Blood Flow Metab. 2011 Jan;31(1):222-234.

 

Michinaga S, Hisatsune A, Isohama Y, Katsuki H.

An anti-Parkinson drug ropinirole depletes orexin from rat hypothalamic slice culture.

Neurosci Res. 2010 Dec;68(4):315-321.

 

Obukuro K, Takigawa M, Hisatsune A, Isohama Y, Katsuki H.

Quinolinate induces selective loss of melanin-concentrating hormone neurons, rather than orexin neurons, in the hypothalamus of mice and young rats.

Neuroscience. 2010 Sep 29;170(1):298-307.

 

Ohnishi M, Katsuki H, Unemura K, Izumi Y, Kume T, Takada-Takatori Y, Akaike A.

Heme oxygenase-1 contributes to pathology associated with thrombin-induced striatal and cortical injury in organotypic slice culture.

Brain Res. 2010 Aug 6;1347:170-178.

 

Ohnishi M, Katsuki H, Izumi Y, Kume T, Takada-Takatori Y, Akaike A.

Mitogen-activated protein kinases support survival of activated microglia that mediate thrombin-induced striatal injury in organotypic slice culture.

J Neurosci Res. 2010 Aug 1;88(10):2155-2164.

 

Katsuki H, Kurosu S, Michinaga S, Hisatsune A, Isohama Y, Izumi Y, Kume T, Akaike A.

Depolarizing stimuli cause persistent and selective loss of orexin in rat hypothalamic slice culture.

Peptides. 2010 Jun;31(6):1131-1138.

 

Nishimoto Y, Hisatsune A, Katsuki H, Miyata T, Yokomizo K, Isohama Y.

Glycyrrhizin attenuates mucus production by inhibition of MUC5AC mRNA expression in vivo and in vitro.

J Pharmacol Sci. 2010;113(1):76-83.

 

Michinaga S, Hisatsune A, Isohama Y, Katsuki H.

Inhibition of neural activity depletes orexin from rat hypothalamic slice culture.

J Neurosci Res. 2010 Jan;88(1):214-221.

 

Hisatsune A, Kawasaki M, Nakayama H, Mikami Y, Miyata T, Isohama Y, Katsuki H, Kim KC.

Internalization of MUC1 by anti-MUC1 antibody from cell membrane through the macropinocytotic pathway.

Biochem Biophys Res Commun. 2009 Oct 30;388(4):677-682.

 

Horie I, Maeda M, Yokoyama S, Hisatsune A, Katsuki H, Miyata T, Isohama Y.

Tumor necrosis factor-a decreases aquaporin-3 expression in DJM-1 keratinocytes.

Biochem Biophys Res Commun. 2009 Sep 25;387(3):564-568.

 

Hama Y, Katsuki H, Izumi Y, Kume T, Akaike A.

Excitotoxicity-associated p53 expression in adult rat retina is mediated by calpain activity but not by Cl- influx.

J Pharmacol Sci. 2009 Aug;110(4):493-496.

 

Izumi Y, Yamamoto N, Matsuo T, Wakita S, Takeuchi H, Kume T, Katsuki H, Sawada H, Akaike A.

Vulnerability to glutamate toxicity of dopaminergic neurons is dependent on endogenous dopamine and MAPK activation.

J Neurochem. 2009 Jul;110(2):745-755.

 

Katsuki H, Kurimoto E, Takemori S, Kurauchi Y, Hisatsune A, Isohama Y, Izumi Y, Kume T, Shudo K, Akaike A.

Retinoic acid receptor stimulation protects midbrain dopaminergic neurons from inflammatory degeneration via BDNF-mediated signaling.

J Neurochem. 2009 Jul;110(2):707-718.

 

Mikami Y, Hisatsune A, Tashiro T, Isohama Y, Katsuki H.

Hypoxia enhances MUC1 expression in a lung adenocarcinoma cell line.

Biochem Biophys Res Commun. 2009 Feb 20;379(4):1060-1065.

 

Kuroiwa A, Hisatsune A, Isohama Y, Katsuki H.

Bacterial neuraminidase increases IL-8 production in lung epithelial cells via NF-kB-dependent pathway.

Biochem Biophys Res Commun. 2009 Feb 13;379(3):754-759.

 

Kume T, Ito R, Taguchi R, Izumi Y, Katsuki H, Niidome T, Takada-Takatori Y, Sugimoto H, Akaike A.

Serofendic acid promotes stellation induced by cAMP and cGMP analogs in cultured cortical astrocytes.

J Pharmacol Sci. 2009 Jan;109(1):110-118.

 

Kurauchi Y, Hisatsune A, Isohama Y, Katsuki H.

Nitric oxide-cyclic GMP signaling pathway limits inflammatory degeneration of midbrain dopaminergic neurons: cell type-specific regulation of heme oxygenase-1 expression.

Neuroscience. 2009 Jan 23;158(2):856-866.

 

Ohnishi M, Katsuki H, Takagi M, Kume T, Akaike A.

Long-term treatment with nicotine suppresses neurotoxicity of, and microglial activation by, thrombin in cortico-striatal slice cultures.

Eur J Pharmacol. 2009 Jan 14;602(2-3):288-293.

 

Kume T, Kawato Y, Osakada F, Izumi Y, Katsuki H, Nakagawa T, Kaneko S, Niidome T, Takada-Takatori Y, Akaike A.

Dibutyryl cyclic AMP induces differentiation of human neuroblastoma SH-SY5Y cells into a noradrenergic phenotype.

Neurosci Lett. 2008 Oct 10;443(3):199-203.

 

Hama Y, Katsuki H, Suminaka C, Kume T, Akaike A.

Chloride-dependent acute excitotoxicity in adult rat retinal ganglion cells.

Neuropharmacology. 2008 Oct;55(5):677-686.

 

Nakamura T, Kume T, Katsuki H, Niidome T, Sugimoto H, Akaike A.

Protective effect of serofendic acid on ischemic injury induced by occlusion of the middle cerebral artery in rats.

Eur J Pharmacol. 2008 May 31;586(1-3):151-155.

 

Takei H, Baba Y, Hisatsune A, Katsuki H, Miyata T, Yokomizo K, Isohama Y.

Glycyrrhizin inhibits interleukin-8 production and nuclear factor-kB activity in lung epithelial cells, but not through glucocorticoid receptors.

J Pharmacol Sci. 2008 Mar;106(3):460-468.

 

Izumi Y, Yamamoto N, Kume T, Katsuki H, Sawada H, Akaike A.

Regulation of intracellular dopamine levels by dopaminergic drugs: involvement of vesicular monoamine transporter.

Eur J Pharmacol. 2008 Mar 17;582(1-3):52-61.

 

Fujimoto S, Katsuki H, Ohnishi M, Takagi M, Kume T, Akaike A.

Plasminogen potentiates thrombin cytotoxicity and contributes to pathology of intracerebral hemorrhage in rats.

J Cereb Blood Flow Metab. 2008 Mar;28(3):506-515.

 

Katsuki H, Watanabe Y, Fujimoto S, Kume T, Akaike A.

Contribution of endogenous glycine and d-serine to excitotoxic and ischemic cell death in rat cerebrocortical slice cultures.

Life Sci. 2007 Aug 9;81(9):740-749.

 

Oda T, Kume T, Katsuki H, Niidome T, Sugimoto H, Akaike A.

Donepezil potentiates nerve growth factor-induced neurite outgrowth in PC12 cells.

J Pharmacol Sci. 2007 Aug;104(4):349-354.

 

Ohnishi M, Katsuki H, Fujimoto S, Takagi M, Kume T, Akaike A.

Involvement of thrombin and mitogen-activated protein kinase pathways in hemorrhagic brain injury.

Exp Neurol. 2007 Jul;206(1):43-52.

 

Izumi Y, Sawada H, Yamamoto N, Kume T, Katsuki H, Shimohama S, Akaike A.

Novel neuroprotective mechanisms of pramipexole, an anti-Parkinson drug, against endogenous dopamine-mediated excitotoxicity.

Eur J Pharmacol. 2007 Feb 28;557(2-3):132-140.

 

Yamamoto N, Sawada H, Izumi Y, Kume T, Katsuki H, Shimohama S, Akaike A.

Proteasome inhibition induces glutathione synthesis and protects cells from oxidative stress: relevance to Parkinson disease.

J Biol Chem. 2007 Feb 16;282(7):4364-4372.

 

Okawara M, Katsuki H, Kurimoto E, Shibata H, Kume T, Akaike A.

Resveratrol protects dopaminergic neurons in midbrain slice culture from multiple insults.

Biochem Pharmacol. 2007 Feb 15;73(4):550-560.

 

Fujimoto S, Katsuki H, Ohnishi M, Takagi M, Kume T, Akaike A.

Thrombin induces striatal neurotoxicity depending on mitogen-activated protein kinase pathways in vivo.

Neuroscience. 2007 Jan 19;144(2):694-701.

 

Takada-Takatori Y, Kume T, Sugimoto M, Katsuki H, Niidome T, Sugimoto H, Fujii T, Okabe S, Akaike A.

Neuroprotective effects of galanthamine and tacrine against glutamate neurotoxicity.

Eur J Pharmacol. 2006 Nov 7;549(1-3):19-26.

 

Hama Y, Katsuki H, Tochikawa Y, Suminaka C, Kume T, Akaike A.

Contribution of endogenous glycine site NMDA agonists to excitotoxic retinal damage in vivo.

Neurosci Res. 2006 Nov;56(3):279-285.

 

Takada-Takatori Y, Kume T, Sugimoto M, Katsuki H, Sugimoto H, Akaike A.

Acetylcholinesterase inhibitors used in treatment of Alzheimer's disease prevent glutamate neurotoxicity via nicotinic acetylcholine receptors and phosphatidylinositol 3-kinase cascade.

Neuropharmacology. 2006 Sep;51(3):474-486.

 

Kume T, Taguchi R, Katsuki H, Akao M, Sugimoto H, Kaneko S, Akaike A.

Serofendic acid, a neuroprotective substance derived from fetal calf serum, inhibits mitochondrial membrane depolarization and caspase-3 activation.

Eur J Pharmacol. 2006 Aug 7;542(1-3):69-76.

 

Katsuki H, Okawara M, Shibata H, Kume T, Akaike A.

Nitric oxide-producing microglia mediate thrombin-induced degeneration of dopaminergic neurons in rat midbrain slice culture.

J Neurochem. 2006 Jun;97(5):1232-1242.

 

Kaneko S, Kawakami S, Hara Y, Wakamori M, Itoh E, Minami T, Takada Y, Kume T, Katsuki H, Mori Y, Akaike A.

A critical role of TRPM2 in neuronal cell death by hydrogen peroxide.

J Pharmacol Sci. 2006 May;101(1):66-76.

 

Fujimoto S, Katsuki H, Kume T, Akaike A.

Thrombin-induced delayed injury involves multiple and distinct signaling pathways in the cerebral cortex and the striatum in organotypic slice cultures.

Neurobiol Dis. 2006 Apr;22(1):130-142.

 

Shirakawa H, Katsuki H, Kume T, Kaneko S, Akaike A.

Aminoglutethimide prevents excitotoxic and ischemic injuries in cortical neurons.

Br J Pharmacol. 2006 Apr;147(7):729-736.

 

Taguchi R, Shirakawa H, Yamaguchi T, Kume T, Katsuki H, Akaike A.

Nitric oxide-mediated effect of nipradilol, an a- and b-adrenergic blocker, on glutamate neurotoxicity in rat cortical cultures.

Eur J Pharmacol. 2006 Mar 27;535(1-3):86-94.

 

Takahata K, Shimazu S, Katsuki H, Yoneda F, Akaike A.

Effects of selegiline on antioxidant systems in the nigrostriatum in rat.

J Neural Transm. 2006 Feb;113(2):151-158.

 

Shibata H, Katsuki H, Okawara M, Kume T, Akaike A.

c-Jun N-terminal kinase inhibition and a-tocopherol protect midbrain dopaminergic neurons from interferon-g/lipopolysaccharide-induced injury without affecting nitric oxide production.

J Neurosci Res. 2006 Jan;83(1):102-109.

 

Kume T, Sugimoto M, Takada Y, Yamaguchi T, Yonezawa A, Katsuki H, Sugimoto H, Akaike A.

Up-regulation of nicotinic acetylcholine receptors by central-type acetylcholinesterase inhibitors in rat cortical neurons.

Eur J Pharmacol. 2005 Dec 19;527(1-3):77-85.

 

Izumi Y, Sawada H, Yamamoto N, Kume T, Katsuki H, Shimohama S, Akaike A.

Iron accelerates the conversion of dopamine-oxidized intermediates into melanin and provides protection in SH-SY5Y cells.

J Neurosci Res. 2005 Oct 1;82(1):126-137.

 

Kume T, Kawai Y, Yoshida K, Nakamizo T, Kanki R, Sawada H, Katsuki H, Shimohama S, Sugimoto H, Akaike A.

Protective effect of serofendic acid on glutamate-induced neurotoxicity in rat cultured motor neurons.

Neurosci Lett. 2005 Aug 5;383(3):199-202.

 

Katsuki H, Akaike A.

Quinolinic acid toxicity on orexin neurons blocked by gamma aminobutyric acid type A receptor stimulation.

Neuroreport. 2005 Aug 1;16(11):1157-1161.

 

Hirami C, Takahata K, Shimazu S, Yoneda F, Hayashi K, Katsuki H, Akaike A.

Effects of R-(-)-BPAP on the expressions of neurotrophins and their receptors in mesencephalic slices.

Biol Pharm Bull. 2005 Aug;28(8):1524-1526.

 

Shirakawa H, Katsuki H, Kume T, Kaneko S, Akaike A.

Pregnenolone sulphate attenuates AMPA cytotoxicity on rat cortical neurons.

Eur J Neurosci. 2005 May;21(9):2329-2335.

 

Izumi Y, Sawada H, Sakka N, Yamamoto N, Kume T, Katsuki H, Shimohama S, Akaike A.

p-Quinone mediates 6-hydroxydopamine-induced dopaminergic neuronal death and ferrous iron accelerates the conversion of p-quinone into melanin extracellularly.

J Neurosci Res. 2005 Mar 15;79(6):849-860.

 

Katsuki H, Shinohara A, Fujimoto S, Kume T, Akaike A.

Tetraethylammonium exacerbates ischemic neuronal injury in rat cerebrocortical slice cultures.

Eur J Pharmacol. 2005 Jan 31;508(1-3):85-91.

 

Osakada F, Hashino A, Kume T, Katsuki H, Kaneko S, Akaike A.

a-tocotrienol provides the most potent neuroprotection among vitamin E analogs on cultured striatal neurons.

Neuropharmacology. 2004 Nov;47(6):904-915.

 

Katsuki H, Nonaka M, Shirakawa H, Kume T, Akaike A.

Endogenous d-serine is involved in induction of neuronal death by N-methyl-d-aspartate and simulated ischemia in rat cerebrocortical slices.

J Pharmacol Exp Ther. 2004 Nov;311(2):836-844.

 

Osakada F, Kawato Y, Kume T, Katsuki H, Sugimoto H, Akaike A.

Serofendic acid, a sulfur-containing diterpenoid derived from fetal calf serum, attenuates reactive oxygen species-induced oxidative stress in cultured striatal neurons.

J Pharmacol Exp Ther. 2004 Oct;311(1):51-59.

 

Fujimoto S, Katsuki H, Kume T, Kaneko S, Akaike A.

Mechanisms of oxygen glucose deprivation-induced glutamate release from cerebrocortical slice cultures.

Neurosci Res. 2004 Oct;50(2):179-187.

 

Katsuki H, Akaike A.

Excitotoxic degeneration of hypothalamic orexin neurons in slice culture.

Neurobiol Dis. 2004 Feb;15(1):61-69.

 

Katsuki H, Yamamoto R, Nakata D, Kume T, Akaike A.

Neuronal nitric oxide synthase is crucial for ganglion cell death in rat retinal explant cultures.

J Pharmacol Sci. 2004 Jan;94(1):77-80.

 

Sakka N, Sawada H, Izumi Y, Kume T, Katsuki H, Kaneko S, Shimohama S, Akaike A.

Dopamine is involved in selectivity of dopaminergic neuronal death by rotenone.

Neuroreport. 2003 Dec 19;14(18):2425-2428.

 

Shimazu S, Tsunekawa H, Yoneda F, Katsuki H, Akaike A, Janowsky A.

Transporter-mediated actions of R-(-)-1-(benzofuran-2-yl)-2-propylaminopentane.

Eur J Pharmacol. 2003 Dec 15;482(1-3):9-16.

 

Taguchi R, Nishikawa H, Kume T, Terauchi T, Kaneko S, Katsuki H, Yonaga M, Sugimoto H, Akaike A.

Serofendic acid prevents acute glutamate neurotoxicity in cultured cortical neurons.

Eur J Pharmacol. 2003 Sep 23;477(3):195-203.

 

Shibata H, Katsuki H, Nishiwaki M, Kume T, Kaneko S, Akaike A.

Lipopolysaccharide-induced dopaminergic cell death in rat midbrain slice cultures: role of inducible nitric oxide synthase and protection by indomethacin.

J Neurochem. 2003 Sep;86(5):1201-1212.

 

Takahata K, Katsuki H, Kume T, Ito K, Tochikawa Y, Muraoka S, Yoneda F, Kashii S, Honda Y, Akaike A.

Retinal neurotoxicity of nitric oxide donors with different half-life of nitric oxide release: involvement of N-methyl-d-aspartate receptor.

J Pharmacol Sci. 2003 Aug;92(4):428-432.

 

Takada Y, Yonezawa A, Kume T, Katsuki H, Kaneko S, Sugimoto H, Akaike A.

Nicotinic acetylcholine receptor-mediated neuroprotection by donepezil against glutamate neurotoxicity in rat cortical neurons.

J Pharmacol Exp Ther. 2003 Aug;306(2):772-777.

 

Katsuki H, Shibata H, Takenaka C, Kume T, Kaneko S, Akaike A.

N-Methyl-d-aspartate receptors contribute to the maintenance of dopaminergic neurons in rat midbrain slice cultures.

Neurosci Lett. 2003 May 1;341(2):123-126.

 

Takahata K, Katsuki H, Kume T, Nakata D, Ito K, Muraoka S, Yoneda F, Kashii S, Honda Y, Akaike A.

Retinal neuronal death induced by intraocular administration of a nitric oxide donor and its rescue by neurotrophic factors in rats.

Invest Ophthalmol Vis Sci. 2003 Apr;44(4):1760-1766.

 

Osakada F, Hashino A, Kume T, Katsuki H, Kaneko S, Akaike A.

Neuroprotective effects of a-tocopherol on oxidative stress in rat striatal cultures.

Eur J Pharmacol. 2003 Mar 28;465(1-2):15-22.

 

Izumi Y, Benz AM, Katsuki H, Matsukawa M, Clifford DB, Zorumski CF.

Effects of fructose-1,6-bisphosphate on morphological and functional neuronal integrity in rat hippocampal slices during energy deprivation.

Neuroscience. 2003;116(2):465-475.

 

Takahata K, Katsuki H, Kobayashi Y, Muraoka S, Yoneda F, Kume T, Kashii S, Honda Y, Akaike A.

Protective effects of selegiline and desmethylselegiline against N-methyl-d-aspartate-induced rat retinal damage.

Eur J Pharmacol. 2003 Jan 1;458(1-2):81-89.

 

Manabe S, Kashii S, Honda Y, Yamamoto R, Katsuki H, Akaike A.

Quantification of axotomized ganglion cell death by explant culture of the rat retina.

Neurosci Lett. 2002 Dec 6;334(1):33-36.

 

Kume T, Nishikawa H, Taguchi R, Hashino A, Katsuki H, Kaneko S, Minami M, Satoh M, Akaike A.

Antagonism of NMDA receptors by s receptor ligands attenuates chemical ischemia-induced neuronal death in vitro.

Eur J Pharmacol. 2002 Nov 29;455(2-3):91-100.

 

Shirakawa H, Katsuki H, Kume T, Kaneko S, Ito J, Akaike A.

Regulation of N-methyl-d-aspartate cytotoxicity by neuroactive steroids in rat cortical neurons.

Eur J Pharmacol. 2002 Nov 15;454(2-3):165-175.

 

Katayama T, Minami M, Nakamura M, Ito M, Katsuki H, Akaike A, Satoh M.

Excitotoxic injury induces production of monocyte chemoattractant protein-1 in rat cortico-striatal slice cultures.

Neurosci Lett. 2002 Aug 16;328(3):277-280.

 

Wang XD, Kashii S, Zhao L, Tonchev AB, Katsuki H, Akaike A, Honda Y, Yamashita J, Yamashima T.

Vitamin B6 protects primate retinal neurons from ischemic injury.

Brain Res. 2002 Jun 14;940(1-2):36-43.

 

Kume T, Asai N, Nishikawa H, Mano N, Terauchi T, Taguchi R, Shirakawa H, Osakada F, Mori H, Asakawa N, Yonaga M, Nishizawa Y, Sugimoto H, Shimohama S, Katsuki H, Kaneko S, Akaike A.

Isolation of a diterpenoid substance with potent neuroprotective activity from fetal calf serum.

Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):3288-3293.

 

Shimazu S, Takahata K, Katsuki H, Tsunekawa H, Tanigawa A, Yoneda F, Knoll J, Akaike A.

(-)-1-(Benzofuran-2-yl)-2-propylaminopentane enhances locomotor activity in rats due to its ability to induce dopamine release.

Eur J Pharmacol. 2001 Jun 15;421(3):181-189.

 

Ibi M, Sawada H, Nakanishi M, Kume T, Katsuki H, Kaneko S, Shimohama S, Akaike A.

Protective effects of 1a,25-(OH)2D3 against the neurotoxicity of glutamate and reactive oxygen species in mesencephalic culture.

Neuropharmacology. 2001 May;40(6):761-771.

 

Katsuki H, Takenaka C, Kume T, Kaneko S, Akaike A.

Requirement of neural activity for the maintenance of dopaminergic neurons in rat midbrain slice cultures.

Neurosci Lett. 2001 Mar 16;300(3):166-170.

 

Katsuki H, Tomita M, Takenaka C, Shirakawa H, Shimazu S, Ibi M, Kume T, Kaneko S, Akaike A.

Superoxide dismutase activity in organotypic midbrain-striatum co-cultures is associated with resistance of dopaminergic neurons to excitotoxicity.

J Neurochem. 2001 Mar;76(5):1336-1345.

 

Katsuki H, Itsukaichi Y, Matsuki N.

Distinct signaling pathways involved in multiple effects of basic fibroblast growth factor on cultured rat hippocampal neurons.

Brain Res. 2000 Dec 8;885(2):240-250.

 

Nishikawa H, Hashino A, Kume T, Katsuki H, Kaneko S, Akaike A.

Involvement of direct inhibition of NMDA receptors in the effects of sigma-receptor ligands on glutamate neurotoxicity in vitro.

Eur J Pharmacol. 2000 Sep 15;404(1-2):41-48.

 

Shimazu S, Katsuki H, Takenaka C, Tomita M, Kume T, Kaneko S, Akaike A.

s receptor ligands attenuate N-methyl-d-aspartate cytotoxicity in dopaminergic neurons of mesencephalic slice cultures.

Eur J Pharmacol. 2000 Jan 28;388(2):139-146.

 

Kume T, Nishikawa H, Tomioka H, Katsuki H, Akaike A, Kaneko S, Maeda T, Kihara T, Shimohama S.

p75-mediated neuroprotection by NGF against glutamate cytotoxicity in cortical cultures.

Brain Res. 2000 Jan 10;852(2):279-289.

 

Ibi M, Sawada H, Kume T, Katsuki H, Kaneko S, Shimohama S, Akaike A.

Depletion of intracellular glutathione increases susceptibility to nitric oxide in mesencephalic dopaminergic neurons.

J Neurochem. 1999 Oct;73(4):1696-1703.

 

Shimazu S, Katsuki H, Akaike A.

Deprenyl rescues dopaminergic neurons in organotypic slice cultures of neonatal rat mesencephalon from N-methyl-d-aspartate toxicity.

Eur J Pharmacol. 1999 Jul 14;377(1):29-34.

 

Katsuki H, Shitaka Y, Saito H, Matsuki N.

A potential role of Ras-mediated signal transduction for the enhancement of depolarization-induced Ca2+ responses in hippocampal neurons by basic fibroblast growth factor.

Dev Brain Res. 1998 Dec 7;111(2):169-176.

 

Izumi Y, Ishii K, Katsuki H, Benz AM, Zorumski CF.

b-Hydroxybutyrate fuels synaptic function during development. Histological and physiological evidence in rat hippocampal slices.

J Clin Invest. 1998 Mar 1;101(5):1121-1132.

 

Izumi Y, Katsuki H, Benz AM, Zorumski CF.

Oxygen deprivation produces delayed inhibition of long-term potentiation by activation of NMDA receptors and nitric oxide synthase.

J Cereb Blood Flow Metab. 1998 Jan;18(1):97-108.

 

Okuda S, Nishiyama N, Saito H, Katsuki H.

3-Hydroxykynurenine, an endogenous oxidative stress generator, causes neuronal cell death with apoptotic features and region selectivity.

J Neurochem. 1998 Jan;70(1):299-307.

 

Izumi Y, Benz AM, Katsuki H, Zorumski CF.

Endogenous monocarboxylates sustain hippocampal synaptic function and morphological integrity during energy deprivation.

J Neurosci. 1997 Dec 15;17(24):9448-9457.

 

Moriguchi T, Matsuura H, Kodera Y, Itakura Y, Katsuki H, Saito H, Nishiyama N.

Neurotrophic activity of organosulfur compounds having a thioallyl group on cultured rat hippocampal neurons.

Neurochem Res. 1997 Dec;22(12):1449-1452.

 

Katsuki H, Nakanishi C, Saito H, Matsuki N.

Biphasic effect of hydrogen peroxide on field potentials in rat hippocampal slices.

Eur J Pharmacol. 1997 Oct 22;337(2-3):213-218.

 

Izumi Y, Katsuki H, Zorumski CF.

Monocarboxylates (pyruvate and lactate) as alternative energy substrates for the induction of long-term potentiation in rat hippocampal slices.

Neurosci Lett. 1997 Aug 22;232(1):17-20.

 

Ikeda Y, Nishiyama N, Saito H, Katsuki H.

Furosemide-sensitive calcium rise induced by GABAA-receptor stimulation in cultures of embryonic rat striatal neurons.

Jpn J Pharmacol. 1997 Jun;74(2):165-169.

 

Katsuki H, Izumi Y, Zorumski CF.

Noradrenergic regulation of synaptic plasticity in the hippocampal CA1 region.

J Neurophysiol. 1997 Jun;77(6):3013-3020.

 

Ikeda Y, Nishiyama N, Saito H, Katsuki H.

GABAA receptor stimulation promotes survival of embryonic rat striatal neurons in culture.

Dev Brain Res. 1997 Feb 20;98(2):253-258.

 

Katsuki H, Izumi Y, Zorumski CF.

Removal of extracellular calcium after conditioning stimulation disrupts long-term potentiation in the CA1 region of rat hippocampal slices.

Neuroscience. 1997 Feb;76(4):1113-1119.

 

Moriguchi T, Matsuura H, Itakura Y, Katsuki H, Saito H, Nishiyama N.

Allixin, a phytoalexin produced by garlic, and its analogues as novel exogenous substances with neurotrophic activity.

Life Sci. 1997;61(14):1413-1420.

 

Yoshida M, Matsuki N, Saito H, Katsuki H.

Effects of coculture with the septum on the expression of long-term potentiation in organotypic hippocampal slice cultures.

Neurosci Res. 1996 Dec;26(4):377-385.

 

Moriguchi T, Nishiyama N, Saito H, Katsuki H.

Trophic effects of aged garlic extract (AGE) and its fractions on primary cultured hippocampal neurons from fetal rat brain.

Phytother Res. 1996;10:468-472.

 

Okuda S, Nishiyama N, Saito H, Katsuki H.

Hydrogen peroxide-mediated neuronal cell death induced by an endogenous neurotoxin, 3-hydroxykynurenine.

Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12553-12558.

 

Shitaka Y, Matsuki N, Saito H, Katsuki H.

Basic fibroblast growth factor increases functional L-type Ca2+ channels in fetal rat hippocampal neurons: implications for neurite morphogenesis in vitro.

J Neurosci. 1996 Oct 15;16(20):6476-6489.

 

Nakagami Y, Saito H, Katsuki H.

3-Hydroxykynurenine toxicity on the rat striatum in vivo.

Jpn J Pharmacol. 1996 Jun;71(2):183-186.

 

Geng MY, Saito H, Katsuki H.

Effects of vitamin B6 and its related compounds on survival of cultured brain neurons.

Neurosci Res. 1995 Dec;24(1):61-65.

 

Geng MY, Saito H, Katsuki H.

The effects of thiamine and oxythiamine on the survival of cultured brain neurons.

Jpn J Pharmacol. 1995 Jul;68(3):349-352.

 

Katsuki H, Akino N, Okuda S, Saito H.

Antioxidants, but not cAMP or high K+, prevent arachidonic acid toxicity on neuronal cultures.

Neuroreport. 1995 May 30;6(8):1101-1104.

 

Yoshida M, Saito H, Katsuki H.

Neurotrophic effects of conditioned media of astrocytes isolated from different brain regions on hippocampal and cortical neurons.

Experientia. 1995 Feb 15;51(2):133-136.

 

Okuda S, Saito H, Katsuki H.

Arachidonic acid: toxic and trophic effects on cultured hippocampal neurons.

Neuroscience. 1994 Dec;63(3):691-699.

 

Kawahara F, Saito H, Katsuki H.

Primary culture of postnatal rat suprachiasmatic neurons in serum-free supplemented medium.

Brain Res. 1994 Jul 18;651(1-2):101-107.

 

Kawahara F, Saito H, Katsuki H.

Inhibition by 5-HT7 receptor stimulation of GABAA receptor-activated current in cultured rat suprachiasmatic neurones.

J Physiol. 1994 Jul 1;478 ( Pt 1):67-73.

 

Filipcik P, Saito H, Katsuki H.

3,5,3'-L-triiodothyronine promotes survival and axon elongation of embryonic rat septal neurons.

Brain Res. 1994 May 30;647(1):148-152.

 

Okuda S, Saito H, Katsuki H.

Divergent trophic actions of glioma conditioned media on cultured rat hippocampal neurons.

Biol Pharm Bull. 1994 May;17(5):735-738.

 

Kawahara F, Saito H, Katsuki H.

Pharmacological characteristics of GABAA responses in postnatal suprachiasmatic neurons in culture.

Neurosci Lett. 1993 Sep 17;160(1):45-48.

 

Sato K, Saito H, Katsuki H.

Synergism of tocopherol and ascorbate on the survival of cultured brain neurones.

Neuroreport. 1993 Sep 3;4(10):1179-1182.

 

Katsuki H, Saito H, Satoh M.

The involvement of muscarinic, b-adrenergic and metabotropic glutamate receptors in long-term potentiation in the fimbria-CA3 pathway of the hippocampus.

Neurosci Lett. 1992 Aug 17;142(2):249-252.

 

Katsuki H, Kaneko S, Satoh M.

Involvement of postsynaptic G proteins in hippocampal long-term potentiation.

Brain Res. 1992 May 22;581(1):108-114.

 

Ishihara K, Katsuki H, Sugimura M, Satoh M.

YM-14673, a new thyrotropin-releasing hormone analog, augments long-term potentiation in the mossy fiber-CA3 system of guinea pig hippocampal slices.

J Pharmacobiodyn. 1992 Feb;15(2):75-78.

 

Katsuki H, Kaneko S, Tajima A, Satoh M.

Separate mechanisms of long-term potentiation in two input systems to CA3 pyramidal neurons of rat hippocampal slices as revealed by the whole-cell patch-clamp technique.

Neurosci Res. 1991 Nov;12(3):393-402.

 

Ishihara K, Katsuki H, Kawabata A, Sasa M, Satoh M, Takaori S.

Effects of thyrotropin-releasing hormone and a related analog, CNK-602A, on long-term potentiation in the mossy fiber-CA3 pathway of guinea pig hippocampal slices.

Brain Res. 1991 Jul 19;554(1-2):203-208.

 

Katsuki H, Ishihara K, Shimada A, Takeda T, Satoh M.

Age-related deterioration of long-term potentiation in the CA3 and CA1 regions of hippocampal slices from the senescence-accelerated mouse.

Arch Gerontol Geriatr. 1990 Jul-Aug;11(1):77-83.

 

Katsuki H, Nakai S, Hirai Y, Akaji K, Kiso Y, Satoh M.

Interleukin-1b inhibits long-term potentiation in the CA3 region of mouse hippocampal slices.

Eur J Pharmacol. 1990 Jun 8;181(3):323-326.

 

Ishihara K, Katsuki H, Sugimura M, Kaneko S, Satoh M.

Different drug-susceptibilities of long-term potentiation in three input systems to the CA3 region of the guinea pig hippocampus in vitro.

Neuropharmacology. 1990 May;29(5):487-492.

 

Sugimura M, Ishihara K, Katsuki H, Satoh M.

Indeloxazine augments long-term potentiation in the mossy fiber-CA3 system of guinea pig hippocampal slices.

J Pharmacobiodyn. 1989 Dec;12(12):771-774.

 

Ishihara K, Katsuki H, Sugimura M, Satoh M.

Idebenone and vinpocetine augment long-term potentiation in hippocampal slices in the guinea pig.

Neuropharmacology. 1989 Jun;28(6):569-573.

 

Satoh M, Ishihara K, Katsuki H.

Different susceptibilities of long-term potentiations in CA3 and CA1 regions of guinea pig hippocampal slices to nootropic drugs.

Neurosci Lett. 1988 Nov 11;93(2-3):236-241.

 

 

 

 英文総説・著書

Katsuki H.

Exploring neuroprotective drug therapies for intracerebral hemorrhage.

J Pharmacol Sci. 2010;114(4):366-378.

 

Katsuki H, Akaike A.

Brain slice preparation for evaluation of the pathophysiological functions of d-serine.

In d-Amino acids: a new frontier in amino acid and protein research. (edited by R. Konno et al.), pp. 185-190, Nova Science Publishers, New York, 2007.

 

Kume T, Katsuki H, Akaike A.

Endogenous factors regulating neuronal death induced by radical stress.

Biol Pharm Bull. 2004 Jul;27(7):964-967.

 

Akaike A, Katsuki H, Kume T.

Pharmacological and physiological properties of serofendic acid, a novel neuroprotective substance isolated from fetal calf serum.

Life Sci. 2003 Dec 5;74(2-3):263-269.

 

Akaike A, Katsuki H, Maeda T, Kume T.

Reactive oxygen species in NMDA receptor-mediated glutamate neurotoxicity.

Parkinsonism & Related Disorders. 1999;5:203-207.

 

Saito H, Moriguchi T, Zhang Y, Katsuki H, Nishiyama N.

Effects of aged garlic extract on rat brain neurons.

In Nutraceuticals: Designer Foods III Garlic, Soy and Licorice (edited by P.A. Lachance), pp. 153-161, Food & Nutrition Press, Trumbull (1997)

 

Nishiyama N, Moriguchi T, Katsuki H, Saito H.

Effects of aged garlic extract on senescence accelerated mouse and cultured brain neurons.

In International Academy for Biomedical and Drug Research, 11: Preclinical and Clinical Strategies for the Treatment of Neurodegenerative, Cerebrovascular and Mental Disorders (edited by T. Shibuya), pp. 253-258, Karger, Basel (1996)

 

Katsuki H.

Vitamin C and nervous tissue. In vivo and in vitro aspects.

Subcell Biochem. 1996;25:293-311.

 

Katsuki H, Okuda S.

Arachidonic acid as a neurotoxic and neurotrophic substance.

Prog Neurobiol. 1995 Aug;46(6):607-636.

 

 

 

 和文

香月博志

視床下部のエネルギーバランス制御機能の破綻にかかわるシグナル分子群.

医学のあゆみ 234, 872-873 (2010).

 

香月博志

神経変性疾患に伴う睡眠・覚醒調節異常.

医学のあゆみ 229, 167-168 (2009).

 

香月博志、赤池昭紀

プロニューロトロフィンの作用とその生理的意義.

医学のあゆみ 226, 511-512 (2008).

 

香月博志、赤池昭紀、浜康博、渡辺佳典

内在性グリシン結合部位リガンドによるNMDA誘発網膜障害の制御.

眼薬理 21, 41-43 (2007).

 

香月博志

ニューロン,グリアと神経保護薬.

21 10, 370-375 (2007).

 

香月博志

神経変性疾患、認知症と興奮性神経毒性.

認知症治療薬開発の最前線(齋藤洋・阿部和穂監修)、pp. 92-108, シーエムシー出版 (2006).

 

赤池昭紀、香月博志、久米利明

ニューロンのアポトーシスを制御する内在性保護因子.

日本神経精神薬理学雑誌 25, 245-250 (2005).

 

香月博志

寿命を制御する脱アセチル化酵素SIRT1.

医学のあゆみ 212, 182-183 (2005).

 

香月博志、赤池昭紀

睡眠障害と視床下部オレキシン.

医学のあゆみ 209, 242-243 (2004).

 

香月博志

脳切片作製法.

生物薬科学実験講座11:神経(脳)IIpp. 24-29, 廣川書店 (2003).

 

香月博志

脊髄損傷後の再生,機能回復と薬物治療

日本薬理学雑誌 120, 260 (2002).

 

赤池昭紀、香月博志、久米利明

神経細胞死・生存におけるNOの役割.

日本薬理学雑誌 119, 15-20 (2002).

 

香月博志

ニューロステロイド.

医学のあゆみ 200, 1221 (2002).

 

香月博志

アミロイドβタンパクとニコチン性アセチルコリン受容体.

日本薬理学雑誌 118, 290 (2001).

 

香月博志、赤池昭紀

ドパミン受容体とParkinson.

別冊・医学のあゆみ 7回膜貫通型受容体研究の新展開(佐藤公道・赤池昭紀編)、pp. 133-137, 医歯薬出版 (2001).

 

赤池昭紀、香月博志、久米利明

グルタミン酸による遅延性神経細胞死に対するニコチンの保護作用.

脳の科学 22, 985-990 (2000).

 

香月博志、赤池昭紀

リガンド受容体チャネル.

現代医療 31, 939-945 (1999).

 

香月博志

神経変性疾患と4-Hydroxynonenal.

ファルマシア 35, 833-834 (1999).

 

香月博志、赤池昭紀

線条体由来非蛋白性物質によるドパミンニューロン死の制御.

別冊・医学のあゆみ 神経細胞死制御(三須良實・赤池昭紀編)、pp. 122-126, 医歯薬出版 (1998).

 

香月博志

脳のエネルギー源:ブドウ糖だけでは脳は育たない?!

日本薬理学雑誌 112, 127 (1998).

 

香月博志

グルタミン酸レセプターを介するCa流入の抑制.

日本薬理学雑誌 97, 15§ (1991).

 

香月博志、佐藤公道

海馬スライス標本の作製法と薬理学的研究への応用.

日本薬理学雑誌 96, 15§–17§ (1990).

 

佐藤公道、香月博志

LTPと老化.

生体の科学 41, 496-500 (1990).