A Case of Cardiac Angiosarcoma Successfully Treated with Postoperative Conformal Dynamic Arc Radiotherapy

(Asahikawa City Hospital, Asahikawa, Japan)

Takahiko Masuda Junichi Oba Tsukasa Miyatake
Kimihiro Yoshimoto Akira Adachi Atsushi Okuyama
Hidetoshi Aoki
Cardiac angiosarcoma is a rare heart malignancy. The prognosis is reported to be very poor. Here, we report a case of cardiac angiosarcoma which was treated by postoperative conformal dynamic arc radiotherapy. The patient has been in good health with no recurrence for 18 months after surgery. The patient was a 71-year-old woman, who presented edema and general malaise. Echocardiography and computed tomography revealed a right atrial mass and massive pericardial effusion, which was thought to be the cause of tamponade. Intraoperatively, we found a large tumor arising from right atrial wall spreading and invading to the inferior vena cava, diaphragm, and right pericardium. We abandoned complete resection of the tumor. We only resected the part of the tumor under cardiopulmonary bypass. The subsequent defect of the right atrial wall was reconstructed with bovine pericardial patch. The pathological diagnosis was consistent with angiosarcoma, and the margin was positive for the tumor. In addition to reduction surgery, we adopted radiotherapy(conformal dynamic arc radiotherapy, 10MV-X-ray, 54Gy/18Fr/4.5week, fractionated radiotherapy). The CT, one month after the radiation, showed a significant reduction in tumor size. Moreover, no tumor could be pointed out by echocardiography 18 months after surgery. Advances in technology and methodology has made tumor control possible without significant side effects. We conclude that reduction surgery accompanied with postoperative radiotherapy is promising in maintaining quality of life and in improving life expectancy.
  Jpn. J. Cardiovasc. Surg. 42:420-424(2013)

Keywords:primary cardiac tumor, cardiac angiosarcoma, postoperative radiotherapy, conformal dynamic arc radiotherapy