Efficacy of Short-Acting β-Blockers after Cardiac Surgery

(Department of Surgery, Cardiovascular Division, Teikyo University School of Medicine)

Haruo Suzuki Susumu Ishikawa Susumu Kadowaki
Keisuke Nakamura Keiko Abe Akio Kawasaki
Kazuo Neya Keisuke Ueda
The efficacy of Landiolol hydrochloride(Onoact®)for the treatment of arrhythmia was studied in 10 adult patients who underwent cardiovascular surgery. Onoact was continuously infused at a mean rate of 0.018mg/kg/min initially and followed by 0.01mg/kg/min. After the initiation of Onoact infusion, supra-ventricular tachycardia was eliminated in 5 out of 6 patients, and ventricular tachycardia disappeared in all 4 patients. The decrease in systemic blood pressure was not significant. Low-dose continuous infusion of Onoact was safe and effective even in patients just after cardiovascular surgery.
  Jpn. J. Cardiovasc. Surg. 38:175-178(2009)