Kenichi Ozaki MD, PhD, Hitoshi Kagaya MD, PhD, Izumi Kondo MD, PhD, Eiichi Saitoh MD, PhD, Sachie Imai MD, PhD, Shigeru Sonoda MD, PhD, Norihide Itoh PT, PhD
Jpn J Compr Rehabil Sci 5: 109-116, 2014
Purpose: We developed a quantitative evaluation
method for motor impairment in hemiplegia using
a three-dimensional motion analysis device, the
Quantified Paralysis Performance Assessment
(QPPA). As a pre-clinical study, we verified the
reproducibility and minimal detectable change of the
method.
Methods: Sixty-six patients who had the first stroke
[39 males, 27 females; aged 60 ± 12 years (mean ±
standard deviation)] were studied. QPPA measurement
was conducted two times to obtain one set of data. The
following measurements were performed; upper limb
function (arm; QPPA-UE) and lower limb functions
(hip joint; QPPA-Hip, knee joint; QPPA-Knee, and
ankle joint; QPPA-Ankle). The lifted distance and
maximum velocity for each marker were used as the
typical values. From the typical values obtained from
one set, the intraclass correlation coefficient (ICC)
and 95% confidence intervals of minimal detectable
change (MDC95) were calculated.
Results: In the case that two sets of data were obtained
from the same acute stage patient at an interval of over
two weeks, the two sets were analyzed individually.
With a total of 91 sets of measurements, the ICCs of
the QPPA indices ranged from 0.956-0.989, and MDC95
ranged from 4.56-6.79%.
Conclusion: The typical values of QPPA showed high
reproducibility. In addition, the minimal detectable
change was small, suggesting that this method captures
clinical changes with higher sensitivity than evaluation
methods using ordinal scales.
Key words: three-dimensional motion analysis, hemiplegia, interval scale