Scientific Program

Monday, November 11, 2002

7:50 - 8:00 Opening Remarks: Toshihiko Kuroiwa Tokyo, Japan
8:00 - 8:20 L1 Lecture: Umeo Ito Tokyo, Japan Clinical strategy for brain edema
Moderators: Alexander Baethmann (Munich, Germany); Geoffrey T. Manley (California, USA)
8:20 - 10:00Oral Presentation: "Blood-Brain Barrier Disorder"
Moderators(1-4): Alexander Baethmann (Munich, Germany); Geoffrey T. Manley (California, USA)
8:201Geoffrey T.ManleyCalifornia, USA Decreased osmotic permeabilty in primary cultured astrocytes from mice deficient in Aquaporin-4
8:332LucaRegliLausanne, Switzerland Aquaporin expression and distribution in human tissue
8:463BelaKisNorth Carolina, USA Adrenomedullin is a potential link between astrocytes and the induction of blood-brain barrier properties in cerebral endothelial cells
8:594FengXiaoLouisiana, USA Matrix metalloproteinases are not involved in early brain edema formation after cardiac arrest in rats
Moderators(5-8): Joseph D. Fenstermacher (Michigan, USA); Yukio Ikeda (Tokyo, Japan)
9:175NobuyukiKawaiKagawa, Japan Treatment of cold injury-induced brain edema with a nonspecific matrix metalloproteinase inhibitor MMI270 in rats
9:307MariaSpatzMaryland, USA Signal transduction pathways in endothelial responses to novel vasoactive substances (endocannabinoids)
9:438Hari S.SharmaUppsala, Sweden Neurotrophic factors attenuate microvascular permeability disturbances and axonal injury following trauma to the rat spinal cord
10:00 - 10:30 Coffee Break and Poster Viewing
10:30 - 11:30 Oral Presentation: "Trauma"
Moderators(9-13): Hiroshi Nawashiro (Saitama, Japan); Robert Vink (South Australia, Australia)
10:309RobertVinkSouth Australia, Australia Neuropeptide release influences brain edema formation after diffuse traumatic brain injury
10:5411NaoyaHattoriCalifornia, USA PET investigations of post-traumatic cerbral blood volume and blood flow
11:0612ArturoChieregatoCesena, Italy Induced acute arterial hypertension and regional cerebral flow in intracontusional low density area
11:1813NaokiOtaniSaitama, Japan A role of glial fibrillary acidic protein in the hippocampal degeneration after traumatic or kainate-induced exitotoxicity
11:30 - 12:00 L2Special Lecture: Igor Klatzo Maryland, USA C. and O. Vogt - the significance of their contributions in modern neuroscience
Moderator: Toshihiko Kuroiwa (Tokyo, Japan)
12:00 - 13:00 Lunch
13:00 - 13:20 L3Lecture: Riki Okeda Tokyo, Japan Hypoxic-ischemic encephalopathy
Moderators: W. D. Heiss (Cologne, Germany); Umeo Ito (Tokyo, Japan)
13:25 - 15:30 Oral Presentation: "Ischemia 1"
Moderators(15-18): W. D. Heiss (Cologne, Germany); Umeo Ito (Tokyo, Japan)
13:2515GuohuaXiMichigan, USA. Thrombin exacerbates brain edema in focal cerebral ischemia
13:3816MasaharuSakohEhime, Japan Prediction of tissue survival after stroke based on changes in the apparent diffusion of water (cytotoxic edema)
13:5117Robert J.DempseyWisconsin, USA Regionally specific neurogenesis in response to focal cerebral ischemia
Moderators(19-22): Minoru Fujiki (Oita, Japan); Konstantin A. Hossmann (Cologne, Germany)
14:2219NobutakaKawaharaTokyo, Japan DNA microarray-based gene expression analysis for induced ischemic tolerance and delayed neuronal death following transient global ischemia in rats
14:3520HiroshiNawashiroSaitama, Japan Post-ischemic transcriptional and translational responses of EC-SOD in mouse brain and serum
14:4821HiroyukiUchinoTokyo, Japan Neuroprotection by differential immunosuppressants following ischemia corresponds with differing abilities to inhibit calcineurin and the mitochondrial permeability transition
15:0122HirokzauUedaOsaka, Japan Regional N-acetyl-aspartate level and immunohistochemical damage after transient forebrain ischemia in gerbils
Poster Discussion A
15:30 - 17:00 Coffee Break and Poster Discussion A
Moderators(PA1-PA8): Zbigniew Czerncki (Warsaw, Poland); Nobuhiko Omori (Okayama, Japan)
15:30PA-1ShingoToyotaKoeln, Germany Prediction of malignant infarction: Perifocal neurochemical monitoring following prolonged MCA occlusion in cats
15:36PA-2HiroshiKamadaOkayama, Japan Temporal and spatial changes of free cholesterol and neutral lipids in rat brain after transient middle cerebral artery occlusion
15:42PA-3HirokazuOhtakiTokyo,Japan Decreased oxidative neuronal cell death after transient middle cerebral artery occlusion in mice lacking interleukin-1
15:48PA-4SadaharuTabuchiYonago, Japan Mice defficient in cytosolic phospholipase A2 are less susceptible to cerebral ischemia/reperfusion injury
16:00PA-6KentaroOhtaOkayama, Japan Dissociative increase of oligodendrocyte progenitor cells between young and aged rats after transient cerebral ischemia
16:06PA-7TakashiMitsuhashiChiba, Japan Regional distribution for potassium and phosphorus in ischemic brain tissue of rats with X-ray fluorescence analysis
16:12PA-8LiYinTokyo, Japan Expression of tumor necrosis factor alpha (TNF alpha) and type I TNF receptor following transient cerebral ischemia
Moderators(PA9-PA15): Julian T. Hoff (Michigan, USA); Tatsuro Kawamata (Tokyo, Japan)
16:18PA-9NaokiOtaniSaitama, Japan Temporal and spatial profile of phosphorylated mitogen-activated protein kinase (MAPK) pathways following lateral fluid percussion brain injury in rats
16:24PA-10WangJunTochigi, Japan Changes of perivascular cells in the process of brain edema induced by cold injury
16:30PA-11ArturoChieregatoCesena, Italy Mixed dishomogeneous hemorrhagic brain contusions. Mapping of cerebral blood flow and frequency of ischenia
16:36PA-12HidehikoKushiTokyo, Japan Neuronal damage in pericontusional edema zone
16:42PA-13Ullrich Meier Berlin, Germany The use of decompressive craniectomy for the management of severe head injuries
16:48PA-14Mostafa A.KhashabAl Khobar, Saudi Arabia The neuropsychological assessment of head injured patients with frontal lobe injury harboring structural frontal lobe damage
16:54PA-15KosakuKinoshitaTokyo, Japan Characteristics of parietal-parasagittal hemorrhage after mild or moderate traumatic brain injury
Poster Discussion B
15:30 - 17:00 Coffee Break and Poster Discussion B
Moderators(PB1-PB8): Alexander Baethmann (Munich, Germany); Ken-ichiro Katsura (Tokyo, Japan)
15:30PB-1TatsuroMoriTokyo, Japan. Inhibition of ERK phosphorylation attenuates MMP-9 upregulation and brain edema following cortical contusion
15:44PB-3T.WinklerUppsala, Sweden Topical application of TNF-α antiserum attenuates spinal cord trauma induced edema formation, microvascular permeability disturbances and cell injury in the rat
15:51PB-4Hari S.SharmaUppsala, Sweden A new antioxidant compound H-290/51 attenuates spinal cord injury induced expression of constitutive and inducible isoforms of nitricoxide synthase and edema formation in the rat
15:58PB-5MitsuruIkedaKobe, Japan Quantitative analysis of hyperosmotic and hypothermic blood-brain barrier opening
16:05PB-6ShigeruHoshinoTokyo, Japan Prion prevents brain damage and blood-brain-barrier disruption after experimental brain injury
16:12PB-7HidehikoKushiTokyo, Japan IL-8 is a key mediator of neuroinflammation in severe head injuries
16:19PB-8TakahiroAtsumiTokyo, Japan The glutamate AMPA receptor antagonist, YM872, attenuates cortical tissue loss, regional cerebral edema, and breakdown of the blood-brain barrier following experimental brain injury in rats
Moderators(PB9 -PB13): Tatsushi Kamiya (Tokyo, Japan); Hari S. Sharma (Uppsala, Sweden)
16:26PB-9Ken-ichiroKatsuraTokyo, Japan Effects of FK506 on protein phosphorylation system in the gerbil hippocampal CA1 neurons
16:33PB-10KeikoSatoOkayama, Japan Highly polysialylated neural cell adhesion molecule (PSA-NCAM) positive cells increased and changed localization in rat hippocampus with exposure to repeated kindled seizures
16:40PB-11NaokiOtaniSaitama, Japan Temporal and spatial phosphorylation of extracellular signal-regulated kinase pathways after kainate-induced seizures in the rat brain
16:47PB-12MasaruYamadaKanagawa Japan Iodoamphetamine (IMP) uptake in the brain is increased after experimental cerebral venous hypertension in the rat
16:54PB-13RyotaKimuraNara,Japan Cytotoxic and vasogenic edema in the pathological process of cerebral venous infarction
17:00 - 18:30 Sponsored Session 1: "Clinical Approaches to Brain Edema: ICP, CPP, and BP Control"
  • Sponsored by: Eisai Co., Ltd., and Mitsubishi Pharma Corporation
  • Chairperson: Yoichi Katayama and David Mendelow
Moderators(S1-1 - S1-4): Yoichi Katayama (Tokyo, Japan); A. David Mendelow (Newcastle upon Tyne, UK)
 S1-1KatsujiShimaSaitama, Japan Hydrostatic brain edema: Basic mechanisms and clinicalaspects
 S1-2YoichiKatayamaTokyo, Japan Cerebral contusion edema: the combination of traumatic and ischemic edema mechanisms
 S1-3Carl-HenrikNordstromLund, Sweden Volume-targeted therapy of increased ICP
 S1-4Anthony MarmarouVirginia, USA The pathophysiologic basis of traumatic brain edema: Current concepts

Tuesday, November 12, 2002

7:50 - 8:20 L4Special Lecture: Seong-Gi Kim Pennsylvania, USA Brain mapping using functional MRI
Moderators: Yoichi Katayama (Tokyo, Japan); Anthony Marmarou (Virginia, USA)
8:20 - 10:00 Oral Presentation: "Imaging and Diagnosis / Tumor"
Moderators(24-27): Yoichi Katayama (Tokyo, Japan); Anthony Marmarou (Virginia, USA)
8:2024W. D.HeissCologne, Germany Identification of malignant brain edema after hemispheric stroke by PET-imaging and microdialysis
8:3325TadashiNariaiTokyo, Japan PET neuroreceptor imaging as predictor of severe cerebral ischemic insult
8:4526Joseph D.FenstermacherMichigan, USA Estimating blood-brain barrier opening in a rat model of hemorrhagic transformation with Patlak plots of Gd-DTPA contrast enhanced MRI
8:5827PeterSmielewskiCambridge, UK Continuous assessment of autoregulation
Moderators(28-31): Lawrence Litt (California, USA); Toshiyuki Shiogai (Kyoto, Japan)
9:1028Marios C.PapadopoulosLondon, UK Role of water channel proteins (Aquaporins) in brain tumor edema
9:2329YaHuaMichigan, USA A thrombin inhibitor reduces brain edema, glioma mass and neurological deficits in a rat glioma model
9:3530Tatsuya NagashimaKobe, Japan Pathophysiology and treatment of brain edema associated with pediatric brain tumors
9:4831GoroNagashimaKanagawa, Japan Tissue reconstruction process in the area of peri-tumoral edema, caused by glioblastoma immunohistochemical and graphical analysis using autopsy brain
10:00 - 10:30 Coffee Break and Poster Viewing
10:30 - 10:50 L5Lecture: Konstantin A. Hossmann Cologne, Germany Non-invasive imaging techniqes for the characterization of brain pathophysiology
Moderator: Hans J. Reulen (Munich, Germany)
10:55 - 11:55 Sponsored Session 2: "New Dimensions of Neuroimaging"
  • Sponsored by: Hitachi Medical Corporation, Nihon Medi-Physics Co., Ltd., Siemens Asahi Medical Technologies Ltd., and TOSHIBA Corporation, Medical Systems Company
  • Chairperson: Kikuo Ohno
Moderator(S2-1 - S2-4): Kikuo Ohno (Tokyo, Japan)
S2-1KyojiroNambuTochigi, Japan Quantitative evaluation of cerebral vascular permeability using multi-slice dynamic CT
S2-2MakotoKato-AzumaTokyo, Japan Development of interface software and implementation of 3D stereotactic surface projections (3D-SSP) for routine brain SPECT image analysis
S2-3OsamuTakizawaTokyo, Japan Recent developments of MR Imaging technique for the investigation of the brain function
S2-4TsuneakiKawaguchiTokyo, Japan Functional brain imaging of optical topography
12:00 - 16:00 Lunch and Excursion
16:30 - 17:30 Oral Presentation: "Ischemia 2"
Moderators(32-36): Carl-Henrik Nordstrom (Lund, Sweden) Katsuji Shima (Saitama, Japan)
16:3032LawrenceLittCalifornia, USA ATP and PCr responses to hypoxia of hypothermic and normothermic respiring, superfused, neonatal rat cerebrocortical silces: An NMR spectroscopy study at 14.1 tesla
16:4233MinoruTomitaTokyo, Japan Astroglial swelling in the neuronal depolarization ensemble
16:5434SeijiYamamotoHamamatsu, Japan A Na+/H+ exchanger inhibitor suppresses cellular swelling and neuronal death induced by glutamate in cultured cortical neurons
17:0635Eiji KumuraOsaka, Japan Significant shrinkage of extracellular space during global cerebral ischemia: Differences in gray and white matter ischemia
17:1836RyszardPlutaWarsaw, Poland Blood-brain barrier dysfunction and amyloid precursor protein accumulation in microvascular compartment following ischemia-reperfusion brain injury with 1-year survival
Poster Discussion C
17:30 - 19:00 Coffee Break and Poster Discussion C
Moderators(PC1-PC7): Tatsuo Mima (Kochi, Japan); Feng Xiao (Louisiana, USA)
17:30PC-1FengXiaoLouisiana, USA The role of Aquaporin 4 in brain edema formation after normothermic and hypothermic cardiac arrest in rats
17:37PC-2KenjiDohiTokyo, Japan Peroxynitrite (ONOO-) expression in the mouse cardiac arrest model
17:44PC-3YohichiImaizumiTokyo, Japan Expression of Heme Oxigenase-1 after global cerebral ischemia in the mice
17:51PC-4HirokazuOhtakiTokyo,Japan The suppression of ischemic neuronal cell death and caspases activation after cerebral ischemia in tumor necrosis factor-alpha (TNF-alpha) gene deficient mice
17:58PC-5NobuhikoOmoriOkayama, Japan Enhanced phosphorylation of PTEN in rat brain after transient middle cerebral artery occlusion
18:05PC-6Satoru IshibashiTokyo, Japan Sensorimotor and cognitive deficits after focal cerebral ischemia in Mongolian gerbils
18:12PC-7KiyoshiHiraiCalifornia, USA AKTphosphorylation and cell survival after hypoxia-induced cytochrome C release in superfused respiring neonatal rat cerebrocortical slices
Moderators(PC9-PC13): A. David Mendelow (Newcastle upon Tyne, UK) Keiko Sato (Okayama, Japan)
18:26PC-9JohoTokumineOkinawa, Japan Spinal GDNF level is increased after transient spinal cord ischemia in the rat
18:33PC-10YojiTanakaTokyo, Japan Recovery of apparent diffusion coefficient in a rat model of embolic stroke does not mean completely salvage from ischemic neuronal injury
18:40PC-11DaisakuKuritaKanagawa, Japan Energy metabolism and cerebral blood flow during cytotoxic brain edema induced by 6-aminonicotinamide
18:47PC-12QingLuSingapore Stroke prevention by candesartan cilexetil in normotensive experimetal stroke rats
18:54PC-13KenjiDohiTokyo, Japan Neuroprotective effect and direct free radical scavenging activity of Choto-san (kampo medicine)
Poster Discussion D
17:30 - 19:00 Coffee Break and Poster Discussion D
Moderators(PD1-PD8): Takehiko Iijima (Tokyo, Japan); Ryszard Pluta (Warsaw, Poland)
17:30PD-1Angela M.AmoriniVirginia, USA The mechanism of traumatic cellular edema development via astrocytic foot processes
17:36PD-2KosakuKinoshitaTokyo, Japan Changes in cerebrovascular response during brain hypothermia after traumatic brain injury
17:42PD-3Ryuta SuzukiYokohama, Japan Ultra early expression of vascular endothelial growth factor in brain edema tissue associated with brain contusion
17:48PD-4ShinjiFukuiVirginia, USA The effect of cyclosporin A on brain edema formation following experimental traumatic brain injury
17:54PD-5HomareNakamuraKanagawa, Japan Free radical reaction and effect of edaravone on experimental brain injury
18:00PD-6YuichiOkaAichi, Japan Expression of mouse brain serine protease (mBSP) mRNA in cold injury model of rat brain
18:06PD-7TakeshiSaitoTokyo, Japan The risk factors for the occurrence of acute brain swelling in acute subdural hematoma
18:12PD-8Mostafa A.KhashabAl Khobar, Saudi Arabia The management of severe head injury with malignant brain edema after evacuation of acute subdural hematoma. A study of the results and response of the edema after surgical evacuation
Moderators(PD10-PD15): Nobutaka Kawahara (Tokyo, Japan) Anthony Marmarou (Virginia, USA)
18:24PD-10AnnaSkottnerUppsala, Sweden Low molecular weight compounds with affinity to melanocortin receptors exert neuroprotection spinal cord injury. An experimental study in the rat
18:30PD-11MinoruFujikiOita, Japan Electrically induced GFAP upregulation attenuates progressive necrosis and caviatation following spinal cord injury
18:36PD-12ChihiroAkiyamaOsaka, Japan Src family kinase inhibitor PP1 improves motor function by reducing edema after spinal cord contusion in rats
18:42PD-13JanWestmanUppsala, Sweden Depletion of endogenous serotonin synthesis with p-CPA, attenuates upregulation of constitutive isoform of Heme Oxygenase-2 expression following a focal trauma to the rat spinal cord
18:48PD-14T.WinklerUppsala, Sweden An L-type calcium channel blocker, Nimodipine influences trauma induced cord conduction and axonal injury in the rat
18:54PD-15John H.ZhangLouisiana, USA Optimal HBO therapeutic windows for acute spinal cord injury in rats

Wednesday, November 13, 2002

7:50 - 8:10 L6Lecture: Julian T. Hoff Michigan, USA Brain edema from intracerebral hemorrhage
Moderators: A. David Mendelow (Newcastle upon Tyne, UK); Seigo Nagao (Kagawa, Japan)
8:10 - 10:15 Oral Presentation: "Intracerebral Hemorrhage, Subarchnoid Hemorrhage, Hydrocephalus"
Moderators(37-41): A. David Mendelow (Newcastle upon Tyne, UK) Seigo Nagao (Kagawa, Japan)
8:1037A DavidMendelowNewcastle upon Tyne, UKThe International surgical trial in intracerebral haemorrhage (ISTICH)
8:2238Juan R.CarhuapomaMichigan, USA.Human brain hemorrhage: Quantification of perihematoma edema using diffusion magnetic resonance imaging
8:3539XiangjunChenMichigan, USA.Thrombin preconditioning upregulates transferrin and transferrin receptor and reduces brain edema induced by lysed red blood cells
8:4740MotokiInajiTokyo, JapanChronological change of perihematomal edema in human intracerebral hemorrhage
9:0041MasahikoKawanishiKagawa, JapanEffect of hypothermia on brain edema formation following intracerebral hemorrhage in rats
Moderators(42-46): Julian T. Hoff (Michigan, USA); Tatsuya Nagashima (Kobe, Japan)
9:1242Zbigniew CzernickiWarsaw, PolandAcute decrease of cerebrocortical microflow and lack of carbon dioxide reactivity following subarachnoid haemorrhage in the rat
9:2543John H.ZhangLouisiana, USAHeat shock protein expression in the brain stem after subarachnoid hemorrhage in rats
9:3744Stephanie C. P.NgNew Territories, Hong KongThe role of ultrasound guided aspiration in the management of patients with thalamic brain haemorrhage: a pilot study with continuous compliance monitoring
9:5045Ullrich Meier Berlin, Germany Does the ventricle size change after shunt operation of normal pressure hydrocephalus?
10:0246TatsuroKawamataTokyo, JapanMetabolic derangements in interstitial brain edema with preserved blood flow: Selective vulnerability of the hippocampal CA3 region in rat hydrocephalus
10:15 - 10:45 Coffee Break and Poster Viewing
10:45 - 11:05 L7Lecture: Alexander Baethmann Munich, Germany Current significance and future perspectives of brain edema research
Moderator: Kintomo Takakura (Tokyo, Japan)
11:10 - 12:30 Sponsored Session 3: "Radiation Effects on Nervous Tissue: Neuromodulation, Injury and Edema"
  • Sponsored by: Elekta K.K., GE Yokogawa Medical Systems, Ltd. and Meditec Corporation
  • Chairperson: Toshiki Yoshimine and Toshihiko Inoue
Moderators(S3-1 - S3-3): Toshihiko Inoue (Osaka, Japan); Toshiki Yoshimine (Osaka, Japan)
S3-1KengoSatoOkayama, JapanRadiation necrosis and brain edema associated with CyberKnife treatment
S3-2Ferenc A. JoleszMassachusetts, USANon-invasive opening of BBB by focused ultrasound
S3-3JeanRegisMarseille, FranceWhat evidence for neuromodulation effects in gamma knife surgery?
12:30 - 13:30Lunch
13:30 - 14:30 Oral Presentation: "Treatment / Others"
Moderators(47-51): Zbigniew Czerncki (Warsaw, Poland); Ryuta Suzuki (Yokohama, Japan)
13:3047TsuneoKanoTokyo, JapanTissue plasminogen activator infiltrates through cerebral vessels: Evaluation using rat embolic stroke model
13:4248TatsushiKamiyaTokyo, JapanMild hypothermia enhances the neuroprotective effect of a selective thrombin inhibitor following transient focal ischemia in rats
13:5449Nils IStahlLund, SwedenIntracerebral microdialysis in severe head injuries, a comparison between different treatment protocols
14:0650TatsuoMimaKochi, JapanDoxorubicin and aclarubicin, RNA synthesis inhibitors, prevented cerebral vasospasm in severe SAH patients
14:1851HirokiKuritaTokyo, JapanRadiation-induced apoptosis of oligodendrocytes in the adult rat brain
Poster Discussion E
14:30 - 16:00 Coffee Break and Poster Discussion E
Moderators(PE1-PE8): Seiji Yamamoto (Hamamatsu, Japan); John H. Zhang (Louisiana, USA)
14:30PE-1TakujiKitaokaMichigan, USAEffect of delayed Argatroban treatment on intracerebral hemorrhage-induced edema in the rat
14:36PE-2TetsuyaMasadaKagawa, JapanAttenuation of intracerebral hemorrhage and thrombin-induced brain edema by overexpression of interleukin-1 receptor antagonist
14:42PE-3KenjiDohiTokyo, JapanTransient elevation of serum bilirubin level (a hemeoxygenase-1 metabolite) in hemorrhagic stroke patients
14:54PE-5John H.ZhangLouisiana, USARole of apoptosis in microvascular permeability increase after SAH
15:00PE-6TatsuoMimaKochi, JapanImportance of microcirculatory disturbances in pathophysiological conditions of SAH: Clinical and experimental evidences
15:06PE-7HiroshiNawashiroSaitama, JapanFocal brain edema and natriuretic peptides in patients with subarachnoid hemorrhage
15:12PE-8Ullrich Meier Berlin, Germany The ICP-dependency of resistance to cerebrospinal fluid outflow: a new mathematical method for CSF-parameter calculation in a model with H-Tx rats
Moderators(PE9-PE15): Nariyuki Hayashi (Tokyo, Japan); Marios C. Papadopoulos (London, UK)
15:18PE-9KotaroOshioCalifornia, USAAquaporin-1 deletion reduces osmotic water permeability and cerebrospinal fluid production
15:24PE-10KenichiIsomuraAichi, JapanExpression of aquapolins in kaolin induced hydrocephalus in rat brain
15:30PE-11PeterSmielewskiCambridge, UKHysteresis of the cerebrospinal pressure-volume curve in patients with hydrocephalus
15:36PE-12ChikakoNitoTokyo, JapanThe effect of radical scavenger, edaravone and extra-mild hypothermia following transient focal ischemia in rats
15:42PE-13JanWestmanUppsala, SwedenAntioxidant compounds EGB-761 and BN 520 21 attenuate brain edema formation and hemeoxygenase (HO) expression following hyperthermic brain injury in the rat
15:48PE-14KosakuKinoshitaTokyo, JapanImportance of hemodynamics management during brain hypothermia in patients with severe head injury
15:54PE-15AtsushiSakuraiTokyo, JapanRelationship between brain oxygen metabolism and temperature gradient between brain and bladder
Poster Discussion F
14:30 - 16:00 Coffee Break and Poster Discussion F
Moderators(PF1-PF8): Tadashi Nariai (Tokyo, Japan); Wai S. Poon (Hong Kong, China)
14:30PF-1Joseph D.FenstermacherMichigan, USATracking neuronal injury by perfusion-and diffuson-weighted MR imaging in a rat model of permanent focal cerebral ischemia
14:36PF-2IchiroYamadaTokyo, JapanTemporal evolution of apparent diffusion coefficient and T2 value following trasient focal cerebral ischmia in gerbils
14:42PF-3AlonsoPenaCambridge, UKTwo-dimensional pq histograms as portraits of global tissue changes in magnetic resonance diffusion tensor imaging
14:48PF-4Ken-ichiMoritaNiigata, JapanDiffusion tensor lambda chart analysis of peritumoral brain edema
14:54PF-5NaoyukiMiyasakaTokyo, JapanDiffusion tensor changes in vasogenic and cellular brain edema in cats
15:00PF-6TakeshiMaedaTokyo, JapanUltra-early study of edema formation in cerebral contusion using diffusion MRI and ADC mapping
15:06PF-7FengXiaoLouisiana, USAReal time monitoring of cerebral hemodynamic and neurometabolic changes by near-infrared spectroscopy following normothermic or hypothermic cardiac arrest in rats
15:12PF-8ToshiyukiShiogaiKyoto, JapanAcetazolamide vasoreactivity evaluated by transcranial harmonic perfusion imaging: Relationship with transcranial doppler sonography and dynamic CT
Moderators(PF9-PF15): Geoffrey T. Manley (California, USA); Nobuyuki Kawai (Kagawa, Japan)
15:18PF-9HironakaIgarashiTokyo, JapanCerebral blood flow index: Dynamic perfusion MRI delivers a simple and good predictor for the outcome of acute stage ischemic lesion
15:24PF-10MakotoNakaneKanagawa, JapanCharacteristic changes of the secondary degeneration in thedorsomedial nucleus of the thalamus on magnetic resonance imaging
15:30PF-11ShoichiroIshiharaSaitama, JapanSpontaneous intracranial hypotension; The early appearance of urinary bladder activity in RI cisternography was not necessary characteristic sign?
15:36PF-12GeoffreyManleyCalifornia, USAExpression of membrane water channels, Aquaporin 1 and Aquaporin 4, in human brain tumors suggests a potential novel therapeutic target for tumor-associated edema
15:42PF-13TatsuoMimaKochi, JapanPotential risk of aggravation of brain edema at the time of chemotherapy against brain tumor
15:48PF-14KojiroWadaKanagawa, JapanMRI analysis of hydrocephalus associated with acoustic neuroma
15:54PF-15HiroshiNawashiroSaitama, JapanVascular endothelial growth factor expression in pituitary adenoma
16:00 - 17:00 Roundtable Discussion
Moderators: Julian T. Hoff (Michigan, USA); Konstantin A. Hossmann (Cologne, Germany); Anthony Marmarou (Virginia, USA)
17:00 - 17:20 Hakone Best Presentation Award / Closing Remarks

Hakone Best Presentation Award

The six most outstanding papers (three from oral presentations, three from poster presentations) will be selected by the International Advisory Board and the Organizing Committee. Prizes will be awarded to the authors at the end of the symposium. Members of the selection committee will be announced on our web site.

Last update: 2002-11-05 12:53:16
Brain Edema 2002