A comprehensive strategy for HIV control

>> to the Website, "Strategy, AIDS Research Center"

• Study on host immune responses against HIV infections

    - Establishment of an AIDS model using MHC-defined macaques

    - Study on virus-specific immune responses in macaque AIDS models

    - Domestic and international study on viral immune escape in HIV-infected humans

    - Elucidation of the immune mechanism for HIV control

• Study on AIDS vaccine development

    - Study on vaccine delivery system

    - Study on antibody-inducing AIDS vaccines

    - Optimization of delivery system for CTL-inducing AIDS vaccines

    - Optimization of antigens for CTL-inducing AIDS vaccines

    - An international project toward a clinical trial of a AIDS vaccine using SeV vectors

• Study on viral evolution

    - Study on virus and host interaction

    - Study on virus and host diversities

• Study on HTLV-1 infection

    - Study on HTLV-1 antigen-specific immune responses

    - Development of an HTLV-1 vaccine

Collaboration

• Primate AIDS models

    - National Institute of Biomedical Innovation, Health and Nutrition, Tsukuba Primate Research Center

        https://www.nibiohn.go.jp/en/activities/primate.html

    - Kyoto University, Institute for Life and Medical Sciences   https://www.infront.kyoto-u.ac.jp/en/?lang=en

    - Kyoto University, Center for the Evolutionary origins of Human Behavior   https://www.ehub-kyoto-u.com/en

• MHC analysis

    - Tokyo Medical and Dental University, Medical Research Institute   https://www.tmd.ac.jp/mri/mri-mpath/index_e.html

    - Kinki University, Faculty of Medicine, Immunology　

• Immunological analysis

    - Kumamoto University, Joint Research Center for Human Retrovirus Infection  https://kumamoto-u-jrchri.jp/en/

    - NIID, Department of Immunology

• Pathological analysis

    - NIID, Department of Pathology　http://www0.nih.go.jp/niid/pathology/English.html

• Vaccine development

    - ID Pharma Co,. Ltd. (I'ROM Group)  https://www.iromgroup.co.jp/group/advanced/

    - International AIDS Vaccine Initiative (IAVI)   https://www.iavi.org/

• HLA-associated HIV genome mutations

    - University of Ghana, Noguchi Memorial Institute for Medical Research   https://www.noguchimedres.org/

    - National Institute of Cholera and Enteric Diseases (NICED)   https://niced.org.in/

    - National Institute of Hygiene and Epidemiology (NIHE)   https://nihe.org.vn/en