• Hiroshi Ishii made an oral presentation at 12th IAS Conference on HIV Science, Brisbane, Australia, in July., 2023.
• Thi Thu Thao Dang reported her work in Microbiol. Spectr.
Dang, T. T. T., Anzurez, A., Nakayama-Hosoya, K., Miki, S., Yamashita, K., de Souza, M., Matano, T., and Kawana-Tachikawa, A. Breadth and Durability of SARS-CoV-2-Specific T Cell Responses following Long-Term Recovery from COVID-19. Microbiol. Spectr., 11:e0214323, 2023.
• Midori Nakamura-Hoshi reported her work in Microbiol. Spectr.
Nakamura-Hoshi, M., Nomura, T., Nishizawa, M., Hau, T. T. T., Yamamoto, H., Okazaki, M., Ishii, H., Yonemitsu, K., Suzaki, Y., Ami, Y., and Matano, T. HTLV-1 Proliferation after CD8+ Cell Depletion by Monoclonal Anti-CD8 Antibody Administration in Latently HTLV-1-Infected Cynomolgus Macaques. Microbiol. Spectr., 11:e0151823, 2023.
• Hiroshi Ishii reported his work in Biochem. Biophys. Res. Commun.
Ishii, H., Jounai, K., Tsuji, R., Ohshio, K., Kaneda, D., Okazaki, M., Harada, S., Fujiwara, D., and Matano, T. Plasmacytoid dendritic cells stimulated with Lactococcus lactis strain Plasma produce soluble factors to suppress SARS-CoV-2 replication. Biochem. Biophys. Res. Commun., 662:26–30, 2023.
• Machiko Otani reported her work in J. Int. AIDS Soc.
Otani, M., Shiino, T., Hachiya, A., Gatanaga, H., Watanabe, D., Minami, R., Nishizawa, M., Teshima, T., Yoshida, S., Ito, T., Hayashida, T., Koga, M., Nagashima, M., Sadamasu, K., Kondo, M., Kato, S., Uno, S., Taniguchi, T., Igari, H., Samukawa, S., … Japanese Drug Resistance HIV-1 Surveillance Network. Association of demographics, HCV co-infection, HIV-1 subtypes and genetic clustering with late HIV diagnosis: a retrospective analysis from the Japanese Drug Resistance HIV-1 Surveillance Network. J. Int. AIDS Soc., 26:e26086, 2023.
• Hiroshi Ishii made an oral presentation at 30th Conference on Retroviruses and Opportunistic Infections, Seattle, WA, US, in Feb., 2023.
• Ai Kawana-Tachikawa, Hiroyuki Yamamoto, Hiroshi Ishii, and Sayuri Seki made oral presentations at The 2nd France-Japan Symposium on HIV/AIDS and infectious disease basic research, Tokyo, Japan, in Nov., 2022.
• Hiroshi Ishii made oral presentations at 6th HVTN Translational HIV Vaccine ESI Conference and 39th Sympojium on NHP Models for AIDS, Portland, US, in Sep., 2022.
• Prince Parbie Kofi reported his work in Front. Microbial.
Parbie, P.K., Abana, C.Z., Kushitor, D., Asigbee, T.W., Ntim, N.A.A., Addo-Tetebo, G., Ansong, M.R., Ofori, S.B., Mizutani, T., Runtuwene, L.R., Nishizawa, M., Ishikawa, K., Kiyono, H., Ampofo, W.K., Matano, T., Bonney, E.Y.*, and Kikuchi, T.* High-level resistance to non-nucleos(t)ide reverse transcriptase inhibitor based first-line antiretroviral therapy in Ghana; a 2017 study. Front. Microbiol. 13:973771, 2022.
• Hau Thi Thu Trang reported her work in AIDS.
Hau, T.T.T., Nishizawa, M., Harada, S., Phan, M.H., Kanno, Y., Nomura, T., Matsuoka, S., Kawana-Tachikawa, A., Hall, W.W., Matano, T., Nguyen, L.A.T., and Yamamoto, H. Association of envelope-specific B-cell differentiation and viral selective pressure signatures in HIV-1 CRF01_AE infection. AIDS 36:1629-1641, 2022.
• Nicholas Nii-Trebi reported his work in PLoS ONE.
Nii-Trebi, N.I., Matsuoka, S., Kawana-Tachikawa, A., Bonney, E.Y., Abana, C.Z., Ofori, S.B., Mizutani, T., Ishizaka, A., Shiino, T., Ohashi, J., Naruse, T.K., Kimura, A., Kiyono, H., Ishikawa, K., Ampofo, W.K., Matano, T. Super high-resolution single-molecule sequence-based typing of HLA class I alleles in HIV-1 infected individuals in Ghana. PLoS ONE, 17:e0269390, 2022.
• Hau Thi Thu Trang reported her work in J. Med. Primatol.
Hau, T.T.T., Kanno, Y., Nishizawa, M., Nomura, T., Matano, T., and Yamamoto, H.* Nef-specific CD107a+ CD4+ T-cell responses in a rhesus macaque (Macaca mulatta) showing partial simian immunodeficiency virus control following passive neutralizing antibody infusion. J. Med. Primatol. 51:56-61, 2022.
• Midori Nakamura-Hoshi and Anzurez Reyes Alitzel Greet made oral presentations at The 22nd Kumamoto AIDS Seminar, Virtual, in Oct., 2021.
• Takushi Nomura reported his work in PLoS Pathog.
Nomura, T., Yamamoto, H., Nishizawa, M., Hau, T.T.T., Harada, S., Ishii, H., Seki, S., Nakamura-Hoshi, M., Okazaki, M., Daigen, S., Kawana-Tachikawa, A., Nagata, N., Iwata-Yoshikawa, N., Shiwa, N., Iida, S., Katano, H., Suzuki, T., Park, E.S., Maeda, K., Suzaki, Y., Ami, Y., and Matano, T.* Subacute SARS-CoV-2 replication can be controlled in the absence of CD8+ T cells in cynomolgus macaques. PLoS Pathog. 17:e1009668, 2021.
• Shoji Miki reported his work in PLoS ONE.
Miki, S., Sasaki, H.*, Horiuchi, H., Miyata, N., Yoshimura, Y., Miyazaki, K., Matsumura, T., Takahashi, Y., Suzuki, T., Matano, T., Kawana-Tachikawa, A., and Tachikawa, N. On-admission SARS-CoV-2 RNAemia as a single potent predictive marker of critical condition development and mortality in COVID-19. PLoS ONE 16:e0254640, 2021.
• Yoshiaki Kanno reported his work in AIDS.
Kanno, Y., Hau, T.T.T., Kurokawa, R., Nomura, T., Nishizawa, M., Matano, T., and Yamamoto, H.* Late-phase dominance of a single epitope-specific CD8+ T-cell response in passive neutralizing antibody-infused SIV controllers. AIDS 35:2281-2288, 2021.
• Yuto Nomura reported his work in Viruses.
Nomura, Y., Matsuoka, S., Okazaki, M., Kuwata, T., Matano, T., and Ishii, H.* Neutralizing antibody induction associated with a germline immunoglobulin gene polymorphism in neutralization-resistant SIVsmE543-3 infection. Viruses 13:1181, 2021.
• Machiko Otani reported her work in Int. J. Infect. Dis.
Otani, M., Shiino, T.*, Kondo, M., Hachiya, A., Nishizawa, M., Kikuchi, T., Matano, T., and Japanese Drug Resistance HIV-1 Surveillance Network. Phylodynamic analysis reveals changing transmission dynamics of HIV-1 CRF01_AE in Japan from heterosexuals to men who have sex with men. Int. J. Infect. Dis. 108:397-405, 2021.
• Parbie Prince Kofi reported his work in Front. Cell. Infect. Microbiol.
Parbie, P.K., Mizutani, T., Ishizaka, A., Kawana-Tachikawa, A., Runtuwene, L.R., Seki, S., Abana, C.Z., Kushitor, D., Bonney, E.Y., Ofori, S.B., Uematsu, S., Imoto, S., Kimura, Y., Kiyono, H., Ishikawa, K., Ampofo, W.K.*, and Matano, T.* Dysbiotic fecal microbiome in HIV-1 infected individuals in Ghana. Front. Cell. Infect. Microbiol. 11:646467, 2021.
• Anzurez Reyes Alitzel Greet reported her work in HLA.
Anzurez, A., Naka, I., Miki, S., Hosoya-Nakayama, K., Isshiki, M., Watanabe, Y., Nakamura-Hoshi, M., Seki, S., Matsumura, T., Takano, T., Onodera, T., Adachi, Y., Moriyama, S., Terahara, K., Tachikawa, N., Yoshimura, Y., Sasaki, H., Horiuchi, H., Miyata, N., Miyazaki, K., Koga, M., Ikeuchi, K., Nagai, H., Saito, M., Adachi, E., Yotsuyanagi, H., Kutsuna, S., Kawashima, A., Miyazato, Y., Kinoshita, N., Kouno, C., Tanaka, K., Takahashi, Y., Suzuki, T., Matano, T., Ohashi, J.*, and Kawana-Tachikawa, A.* Association of Human Leukocyte Antigen DRB1*09:01 with severe COVID-19. HLA 98:37-42, 2021.
• Saori Matsuoka and Hiroshi Ishii reported their work in J. Virol.
Matsuoka, S.1, Kuwata, T.1*, Ishii, H.1, Sekizuka, T., Kuroda, M., Sano, M., Okazaki, M., Yamamoto, H., Shimizu, M., Matsushita, S., Seki, Y., Saito, A., Sakawaki, H., Hirsch, V.M., Miura, T., Akari, H., and Matano, T.* A potent anti-simian immunodeficiency virus neutralizing antibody induction associated with a germline immunoglobulin gene polymorphism in rhesus macaques. J. Virol. 95:e02455-20, 2021.
• Parbie Prince Kofi reported his work in Jpn. J. Infect. Dis.
Parbie, P.K., Mizutani, T., Ishizaka, A., Kawana-Tachikawa, A., Runtuwene, L.R., Seki, S., Abana, C.Z., Kushitor, D., Bonney, E.Y., Ofori, S.B., Uematsu, S., Imoto, S., Kimura, Y., Kiyono, H., Ishikawa, K., Ampofo, W.K., and Matano, T.* Fecal microbiome composition in healthy adults in Ghana. Jpn. J. Infect. Dis. 74:42-47, 2021.
• Hiroshi Ishii made an oral presentation at 4th HIV Research for Prevention Conference, HIVR4P, Virtual, in Jan., 2021.
• Midori Nakamura-Hoshi and Hau Thi Thu Trang made oral presentations at The 21st Kumamoto AIDS Seminar, Virtual, in Nov., 2020.
• Hiroshi Ishii made an oral presentation at The 23rd International AIDS Conference, AIDS2020, Virtual, in Jul., 2020.
• Midori Nakamura-Hoshi reported her work in Sci. Rep.
Nakamura-Hoshi, M., Takahara, Y., Matsuoka, S., Ishii, H., Seki, S., Nomura, T., Yamamoto, H., Sakawaki, H., Miura, T., Tokusumi, T., Shu, T., and Matano, T.* Therapeutic vaccine-mediated Gag-specific CD8+ T-cell induction under anti-retroviral therapy augments anti-virus efficacy of CD8+ cells in simian immunodeficiency virus-infected macaques. Sci. Rep. 10:11394, 2020.
• Hiroyuki Yamamoto, Hiroshi Ishii, and Tetsuro Matano made a publication in Mucosal Vaccines.
Yamamoto, H., Ishii, H., and Matano, T.* Mucosal vaccines against HIV/SIV infection. Mucosal Vaccines, 2nd Ed. (Ed.: Kiyono, H. and Pascual, D.W.), Academic Press, Chapter 42, p.713-722, 2020.
• Hiroshi Ishii reported his work in J. Virol.
Ishii, H., Terahara, K., Nomura, T., Takeda, A., Okazaki, M., Yamamoto, H., Tokusumi, T., Shu, T., and Matano, T.* A novel immunogen selectively eliciting CD8+ T cells but not CD4+ T cells targeting immunodeficiency virus antigens. J. Virol. 94:e01876-19, 2020.
• Midori Nakamura-Hoshi reported her work in Jpn. J. Infect. Dis.
Nakamura-Hoshi, M., Suzuki, T., Ainai, A., Hasegawa, H., Ishii, H., and Matano, T.* Inefficient Tax-specific T-cell responses in mice after syngeneic transplantation with tax-transgenic mouse-derived adult T-cell leukemia cells. Jpn. J. Infect. Dis. 73:221-225, 2020.
• Hiroshi Ishii and Saori Matsuoka reported their work in Biochem. Biophys. Res. Commun.
Ishii, H.1, Matsuoka, S.1, Ikeda, N., Kurihara, K., Ueno, T., Takiguchi, M., Naruse, T.K., Kimura, A., Yokoyama, M., Sato, H., and Matano, T.* Determination of a T cell receptor of potent CD8+ T cells against simian immunodeficiency virus infection in Burmese rhesus macaques. Biochem. Biophys. Res. Commun. 521:894-899, 2020.
• Yoshiaki Kanno and Parbie Prince Kofi made oral presentations at The 3rd Japan-Taiwan Joint Symposium on HIV/AIDS, Tokyo, Japan, in Dec., 2019.
• Saori Matsuoka reported her work in Prev. Med. Rep.
Matsuoka, S., Nagashima, M., Sadamasu, K., Mori, H., Kawahata, T., Zaitsu, S., Nakamura, A., de Souza, M.S., and Matano, T.* Estimating HIV-1 incidence in Japan from the proportion of recent infections. Prev. Med. Rep. 16:100994, 2019.
• Adusei-Poku Mildred Amoa-Bosompem reported her work in Jpn. J. Infect. Dis.
Adusei-Poku, M.A., Matsuoka, S., Bonney, E.Y., Abana, C.Z., Duker, E.O., Nii-Trebi, N.I., Ofori, S.B., Mizutani, T., Ishizaka, A., Shiino, T., Kawana-Tachikawa, A., Ishikawa, K., Ampofo, W.K., and Matano, T.* Human leukocyte antigen-associated HIV-1 CRF02_AG gag and vif polymorphisms in Ghana. Jpn. J. Infect. Dis. 72:374-380, 2019.
• Lecture : Matano, T.
A vaccine selectively eliciting Gag/Vif-specific CD8+ T but not CD4+ T cells. France-Japan Symposium on HIV and Hepatitis Basic Research, Paris, France, 10/14-16/2019.
• Lecture : Yamamoto, H.
Dynamics of neutralizing antibody induction against highly resistant SIV. France-Japan Symposium on HIV and Hepatitis Basic Research, Paris, France, 10/14-16/2019.
• Yuta Hikichi reported his work in Virology.
Hikichi, Y.1, Takeda, E.1, Fujino, M., Nakayama, E., Matano, T., and Murakami, T.* HIV-1 matrix mutations that alter Gag membrane binding modulate mature core formation and post-entry events. Virology 532:97-107, 2019.
• Hau Thi Thu Trang and Midori Nakamura-Hoshi reported their work in Biochem. Biophys. Res. Commun.
Hau, T.T.T.1, Nakamura-Hoshi, M.1, Kanno, Y., Nomura, T., Nishizawa, M., Seki, S., Ishii, H., Kawana-Tachikawa, A., Hall, W.W., Nguyen, L.A.T.*, Matano, T.*, and Yamamoto, H.* CD8+ T cell-based strong selective pressure on multiple simian immunodeficiency virus targets in macaques possessing a protective MHC class I haplotype. Biochem. Biophys. Res. Commun. 512:213-217, 2019.
• Naofumi Takahashi and Saori Matsuoka reported their work in Microbes Infect.
Takahashi, N.1, Matsuoka S.1, Minh, T.T.T., Ba, H.P., Naruse, T.K., Kimura, A., Shiino, T., Kawana-Tachikawa, A., Ishikawa, K., Matano, T.*, and Thi, L.A.N.* Human leukocyte antigen-associated gag and nef polymorphisms in HIV-1 subtype A/E-infected individuals in Vietnam. Microbes Infect. 21:113-118, 2019.
• Midori Nakamura-Hoshi and Hau Thi Thu Trang made an oral presentation at The 2nd Japan-Taiwan Joint Symposium on HIV/AIDS, Taipei, Taiwan, in Nov., 2018.
• Yoshiaki Kanno made an oral presentation at The 1st Japan-Taiwan Joint Symposium on HIV/AIDS, Tokyo, Japan, in Dec., 2017.
• Lecture : Matano, T.
Dynamics of wild-type and mutant epitope-specific CD8+ T-cell responses in SIV infection. The 18th Kumamoto AIDS Seminar, Kumamoto, Japan, 10/30/2017.
• Nicholas Israel Nii-Trebi reported his work in J. Med. Microbiol.
Nii-Trebi, N.I., Brandful, J.A.M., Ibe, S., Sugiura, W., Barnor, J.S., Bampoe, P., Yamaoka, S., Matano, T., Yoshimura, K., Ishikawa, K., and Ampofo, W.K.* Dynamic HIV-1 genetic recombination and genotypic drug resistance among treatment-experienced adults in northern Ghana. J. Med. Microbiol. 66:1663-1672, 2017.
• Sayuri Seki, Takushi Nomura, and Masako Nishizawa reported their work in PLoS Pathog.
Seki, S.1, Nomura, T.1, Nishizawa, M.1, Yamamoto, H., Ishii, H., Matsuoka, S., Shiino, T., Sato, H., Mizuta, K., Sakawaki, H., Miura, T., Naruse, T.K., Kimura, A., and Matano, T.* In vivo virulence of MHC-adapted AIDS virus serially-passaged through MHC-mismatched hosts. PLoS Pathog. 13:e1006638, 2017.
• The result of phase I clinical trial using SeV vector (S001) was reported in J. Infect. Dis.
Nyombayire, J., Anzala, O., Gazzard, B., Karita, E., Bergin, P., Hayes, P., Kopycinski, J., Omosa-Manyonyi, G., Jackson, A., Bizimana, J., Farah, B., Sayeed, E., Parks, C.L., Inoue, M., Hironaka, T., Hara, H., Shu, T., Matano, T., Dally, L., Barin, B., Park, H., Gilmour, J., Lombardo, A., Excler, J.-L., Fast, P., Laufer, D.S., Cox, J.H., and the S001 Study Team. First-in-human evaluation of the safety and immunogenicity of a replicating intranasally administered Sendai HIV-1 Gag vaccine: induction of potent T-cell or antibody responses in prime-boost regimens. J. Infect. Dis., in press.
• Koji Sakai has reported his work in Genome Announc.
Sakai, K., Ami, Y., Suzaki, Y., and Matano, T. First complete genome sequence of a simian foamy virus isolate from a cynomolgus macaque. Genome Announc. 4:e01332-16, 2016.
• Lecture: Yamamoto, H. Anti-SIV neutralizing antibodies: T-cell/B-cell synergism in induction and protection. The 30th Annual Meeting of the Japanese Society for AIDS Research, Kagoshima, Japan, 11/24/2016.
• Lecture: Matano, T. Virus-host immune interaction in SIV infection. The 17th Kumamoto AIDS Seminar, Kumamoto, Japan, 10/31/2016.
• Hiroyuki Yamamoto made a publication in Front. Microbiol.
Yamamoto, H. and Matano, T. Patterns of HIV/SIV Prevention and Control by Passive Antibody Immunization. Front. Microbiol. 7:1739, 2016.
• Hiroyuki Yamamoto made an oral presentation at The 34th Annual Symposium on Nonhuman Primate Models for AIDS, New Orlens, LA, USA, in Oct., 2016.
• Hikichi Yuta has reported his work in J. Gen. Virol.
Hikichi, Y., Yokoyama, M., Takemura, T., Fujino, M., Kumakura, S., Maeda, Y., Yamamoto, N., Sato, H., Matano, T., and Murakami, T. Increased HIV-1 sensitivity to neutralizing antibodies by mutations in the Env V3-coding region for resistance to CXCR4 antagonists. J. Gen. Virol. 97:2427-2440, 2016.
• Tetsuo Tsukamoto has reported his work in Med. Hypotheses.
Tsukamoto, T., Yamamoto, H., Okada, S., and Matano, T. Recursion-based depletion of human immunodeficiency virus-specific naïve CD4+ T cells may facilitate persistent viral replication and chronic viraemia leading to acquired immunodeficiency syndrome. Med. Hypotheses 94:81-85, 2016.
• Hiroyuki Yamamoto has reported his work in AIDS.
Yamamoto, H., Iseda, S., Nakane, T., Nomura, T., Takahashi, N., Seki, S., Nakamura, M., Ishii, H., and Matano, T. Augmentation of anti-simian immunodeficiency virus activity in CD8+ cells by neutralizing but not nonneutralizing antibodies in the acute phase. AIDS. 30:2391-4239, 2016.
• Sayuri Seki made an oral presentation at The 15th Awaji International Forum on Infection and Immunity, Hyogo, Japan, in Sep., 2016.
• Hiroshi Ishii has reported his work in Scientific Reports.
Ishii, H., Matsuoka, S., Nomura, T., Nakamura, M., Shiino, T., Sato, Y., Iwata-Yoshikawa, N., Hasegawa, H., Mizuta, K., Sakawaki, H., Miura, T., Koyanagi, Y., Naruse, T.K., Kimura, A., and Matano, T. Association of lymph-node antigens with lower Gag-specific central-memory and higher Env-specific effector-memory CD8+ T-cell frequencies in a macaque AIDS model. Scientific Reports 6:30153, 2016.
• Sumire Iseda has reported his work in J. Virol.
Iseda, S., Takahashi, N., Poplimont, H., Nomura, T., Seki, S., Nakane, T., Nakamura, M., Shi, S., Ishii, H., Furukawa, S., Harada, S., Naruse, T.K., Kimura, A., Matano, T., and Yamamoto, H. Biphasic CD8+ T-cell defense in simian immunodeficiency virus control byacute-phase passive neutralizing antibody immunization. J. Virol. 90:6276-6290, 2016.
• Sayuri Seki made a publication in Exp. Rev. Vaccines.
Seki, S., and Matano, T. Development of a Sendai virus vector-based AIDS vaccine inducing T cell responses. Exp. Rev. Vaccines 15:119-127, 2016.
• Lecture: Matano, T. Virus evolution with accumulation of CD8+ T-cell escape mutations after multiple SIV transmissions among MHC-I-mismatched macaques. The 63rd Annual Meeting of the Japanese Society for Virology, Fukuoka, Japan, 11/22/2015.
• Hiroshi Ishii made a publication in Vaccine.
Ishii, H., and Matano, T. Development of an AIDS vaccine using Sendai virus vectors. Vaccine 33:6061-6065, 2015.
• Takushi Nomura has reported his work in PLoS Pathog.
Nomura, T., Yamamoto, H., Ishii, H., Akari, H., Naruse, T.K., Kimura, A., and Matano, T. Broadening of virus-specific CD8+ T-cell responses is indicative of residual viral replication in aviremic SIV controllers. PLoS Pathog. 11:e1005247, 2015.
• Masako Nishizawa has reported his work in PLoS ONE.
Nishizawa, M., Matsuda, M., Hattori, J., Shiino, T., Matano, T., and Sugiura, W. Longitudinal detection and persistence of minority drug-resistant populations and their effect on salvage therapy. PLoS ONE 10:e0135941, 2015.
• Midori Nakamura made an oral presentation at The 14th Awaji International Forum on Infection and Immunity, Hyogo, Japan, in Sep., 2015.
• Hiroshi Ishii made oral presentations at The 6th Japan-Korea Joint Symposium on HIV/AIDS, Kumamoto, Japan, in Jan., 2015.
• Lecture: Matano, T. A sendai virus vector vaccine against HIV infection. The 62nd Annual Meeting of the Japanese Society for Virology, Yokohama, Japan, 11/10/2014.
• Lecture: Matano, T. Depletion of vaccine-induced CD107a- CD4+ T cells following SIV infection. The 15th Kumamoto AIDS Seminar, Kumamoto, Japan, 10/1/2014.
• Lecture: Yamamoto, H. In vivo determinants of SIV neutralizing antibody induction. The 15th Kumamoto AIDS Seminar, Kumamoto, Japan, 10/1/2014.
• Lecture: Matano, T. Deletion of vaccine-induced CD107a-CD4+ T cells following AIDS virus infection. The 13th Awaji International Forum on Infection and Immunity, Nara, Japan, 9/25/2014.
• Takushi Nomura has reported his work in BBRC.
Nomura, T., Yamamoto, H., Takahashi, N., Naruse, T.K., Kimura, A., and Matano, T. Identification of SIV Nef CD8+ T cell epitopes restricted by a MHC class I haplotype associated with lower viral loads in a macaque AIDS model. Biochem. Biophys. Res. Commun. 450:942-947, 2014.
• Nami Iwamoto has reported her work in J. Virol.
Iwamoto, N., Takahashi, N., Seki, S., Nomura, T., Yamamoto, H., Inoue, M., Shu, T., Naruse, T.K., Kimura, A., and Matano, T. Control of SIV replication by vaccine-induced Gag- and Vif-specific CD8+ T cells. J. Virol. 88:425-433, 2014.
• Masako Nishizawa has reported her work in PLoS ONE.
Nishizawa, M., Hattori, J., Shiino, T., Matano, T., Heneine, W., Johnson, J.A., and Sugiura, W. Highly-sensitive allele-specific PCR testing identifies a greater prevalence of transmitted HIV drug resistance in Japan. PLoS ONE 8:e83150, 2013.
• Naofumi Takahashi made oral presentations at The 5th Japan-Korea Joint Symposium on HIV/AIDS, Seoul, Korea, in Dec., 2013.
• Midori Nakamura made an oral presentation at The 31st Annual Symposium on Nonhuman Primate Models for AIDS Atlanta, GA, USA, in Nov., 2013.
• Lecture: Matano, T. Vif can be a promising CD8 T cell target for HIV/SIV control. The 14th Kumamoto AIDS Seminar, Kumamoto, Japan, 10/29/2013.
• Lecture: Matano, T. Sendai virus vector vaccine. AIDS Vaccine 2013 (Symposium 04: Viral Vaccine Vectors), Barcelonae, Spain, 10/9/2013.
• Taku Nakane has reported his work in PLoS ONE.
Nakane, T., Nomura, T., Shi, S., Nakamura, M., Naruse, T.K., Kimura, A., Matano, T., and Yamamoto, H. Limited impact of passive non-neutralizing antibody immunization in acute SIV infection on viremia control in rhesus macaques. PLoS ONE 8:e73453, 2013.
• Shoi Shi has reported his work in Microbes Infect.
Shi, S., Seki, S., Matano, T., and Yamamoto, H. IL-21-producer CD4+ T cell kinetics during primary simian immunodeficiency virus infection. Microbes Infect. 15:697-707, 2013.
• Hiroyuki Yamamoto made an oral presentation at The 12th Awaji International Forum on Infection and Immunity, Hyogo, Japan, in Sep., 2013.
• Tetsuro Matano & Koichi Ishikawa visited Noguchi Memorial Institute for Medical Research in Ghana for an international collaborative project in June, 2013.
• The New York-based International AIDS Vaccine Initiative (IAVI) and the Japan-based biotech DNAVEC Corporation announced the start of a Phase I clinical trial of an HIV vaccine candidate using Sendai virus (SeV) vector at three locations including England and Rwanda. The SeV vector AIDS vaccine system has been developed by our research group. (2013.4.2)
Press release from IAVI on April 1, 2013
Information on this project in IAVI Web
http://www.iavi.org/Information-Center/Publications/Pages/AIDS-Vaccine-Development-in-Japan.aspx
• Lecture: Matano T. Viral control mechanisms in a macaque AIDS model. US-Japan Cooperative Medical Science Program, Joint Meeting of the AIDS Panels, Singapore, Singapore, 3/13/2013.>
• Lecture: Matano, T. Possible Contribution of Gag/Vif/Nef-specific CD8T-cell Responses to SIV Control. Miami CFAR (Center for AIDS Research) Seminar, Miami, FL, USA, 3/8/2013.
• Naofumi Takahashi has reported his work in PLoS ONE.
Takahashi, N., Nomura, T., Takahara, Y., Yamamoto, H., Shiino, T., Takeda, A., Inoue, M., Iida, A., Hara, H., Shu, T., Hasegawa, M., Sakawaki, H., Miura, T., Igarashi, T., Koyanagi, Y., Naruse, T.K., Kimura, A., and Matano, T. A novel protective MHC-I haplotype not associated with dominant Gag-specific CD8+ T-cell responses in SIVmac239 infection of Burmese rhesus macaques. PLoS ONE 8:e54300, 2013.
• Takushi Nomura and Naofumi Takahashi made oral presentations at The 4th Japan-Korea Joint Symposium on HIV/AIDS, Tokyo, Japan, in Dec., 2012.
• Lecture: Matano, T. HIV vaccine development. Symposium on Research and Quality Control of Vaccines, Beijing, China, 2/20/2012.
• Lecture: Yamamoto, H. In vivo correlates of neutralizing antibody induction against SIVmac239. International Symposium on Basic Research towards HIV Control, The 26th Annual Meeting of the Japanese Society for AIDS Research, Tokyo, Japan, 11/25/2012.
• Kyoko Kurihara has reported her work in Microbes Infect.
Kurihara, K., Takahara, Y., Nomura, T., Ishii, H., Iwamoto, N., Takahashi, N., Inoue, M., Iida, A., Hara, H., Shu, T., Hasegawa, M., Moriya, C., and Matano, T. Immunogenicity of repeated Sendai viral vector vaccination in macaques. Microbes Infect. 14:1169-1176, 2012.
• Nami Iwamoto made an oral presentation at The 13th Kumamoto AIDS Seminar, Kumamoto, Japan, in Oct., 2012.
• Lecture: Matano, T. Stable viral control in the presence of silent proviruses in a macaque AIDS model. The 13th Kumamoto AIDS Seminar, Kumamoto, Japan, 10/24/2012.
• Lecture: Matano, T. SIV control by vaccine-based Gag/Vif-specific CTL induction. The 14th Annual Meeting of the Institute of Human Virology, Baltimore, MD, USA, 10/16/2012.
• Midori Nakamura made an oral presentation at The 11th Awaji International Forum on Infection and Immunity, Hyogo, Japan, in Sep., 2012.
• Hiroshi Ishii made an oral presentation at 2012 International Student Research Forum, Omaha, NE, USA, in Aug., 2012.
• Yusuke Takahara made an oral presentation at Towards an HIV Cure Pre-Conference Symposium, IAS, Washington DC, USA, in Jul., 2012.
• Takushi Nomura made a publication in Front. Microbio.
Nomura, T., and Matano, T. Association of MHC-I genotypes with disease progression in HIV/SIV infections. Front. Microbio. 3:234, 2012.
• Lecture: Matano, T. Current progress in development of an AIDS vaccine. Soft Opening Research Hospital of Tropical & Infectious Disease, Airlangga University, Surabaya, Indonesia, 5/28/2012.
• Takushi Nomura has reported his work in J. Virol.
Nomura, T., Yamamoto, H., Shiino, T., Takahashi, N., Nakane, T., Iwamoto, N., Ishii, H., Tsukamoto, T., Kawada, M., Matsuoka, S., Takeda, A., Terahara, K., Tsunetsugu-Yokota, Y., Iwata-Yoshikawa, N., Hasegawa, H., Sata, T., Naruse, T.K., Kimura, A., and Matano, T. Association of major histocompatibility complex class I haplotypes with disease progression after simian immunodeficiency virus challenge in Burmese rhesus macaques. J. Virol. 86:6481-6490, 2012.
• Koichi Ishikawa & Taku Nakane visited Noguchi Memorial Institute for Medical Research in Ghana for an international collaborative project in March, 2012.
• Dr. Hiroaki Takeuchi reported his work in Retrovirology.
Takeuchi, H., Ishii, H., Kuwano, T., Inagaki, N., Akari, H., and Matano, T. Host cell species-specific effect of cyclosporine A on simian immunodeficiency virus replication. Retrovirology 9:3, 2012.
• Sayuri Seki made a publication in Front. Microbiol.
Seki, S., and Matano, T. CTL escape and viral fitness in HIV/SIV infection. Front. Microbiol. 2:267, 2012.
• Lecture: Matano, T. HIV vaccine development. Symposium on Research and Quality Control of Vaccines, Beijing, China, 2/20/2012.
• Hiroshi Ishii reported his work in J. Virol.
Ishii, H., Kawada, M., Tsukamoto, T., Yamamoto, H., Matsuoka, S., Shiino, T., Takeda, A., Inoue, M., Iida, A., Hara, H., Shu, T., Hasegawa, M., Naruse, T.K., Kimura, A., Takiguchi, M., and Matano, T. Impact of vaccination on cytotoxic T lymphocyte immunodominance and cooperation against simian immunodeficiency virus replication in rhesus macaques. J. Virol. 86:738-745, 2012.
• Midori Nakamura made an oral presentation at The 3rd Korea-Japan Joint Symposium on HIV/AIDS, Seoul, Korea, in Dec., 2011.
• Dr. Chikaya Moriya reported her work in Vaccine.
Moriya, C., Horiba, S., Kurihara, K., Kamada, T., Takahara, Y., Inoue, M., Iida, A., Hara, H., Shu, T., Hasegawa, M., and Matano, T. Intranasal Sendai viral vector vaccination is more immunogenic than intramuscular under pre-existing anti-vector antibodies. Vaccine 29:8557-8563, 2011.
• Midori Nakamura reported her work in Microbiol. Immunol.
Nakamura, M., Takahara, Y., Ishii, H., Sakawaki, H., Horiike, M., Miura, T., Igarashi, T., Naruse, T.K., Kimura, A., Matano, T., and Matsuoka, S. Major histocompatibility complex class I-restricted cytotoxic T lymphocyte responses during primary simian immunodeficiency virus infection in Burmese rhesus macaques. Microbiol. Immunol. 55:768-773, 2011.
• Lecture: Matano, T. Impact of prophylactic vaccination on post-exposure CTL cooperation against SIV replication in rhesus macaques. The 12th Kumamoto AIDS Seminar, Kumamoto, Japan, 10/20/2011.
• Yusuke Takahara made an oral presentation at The 12th Kumamoto AIDS Seminar, Kumamoto, in Oct., 2011.
• Lecture: Matano, T. Impact of prophylactic vaccination with Sendai viral vectors on post-challenge CTL responses in a macaque AIDS model. The 5th Vaccine and ISV Annual Global Congress, Seattle, WA, USA, 10/2/2011.
• Dr. Tetsuro Matano attended the 25th Joint Meeting of the United States-Japan Cooperative Medical Science Program AIDS Panels at Atlanta, GA, in Sep., 2011.
• Hiroshi Ishii and Takushi Nomura made oral presentations at The XVth International Congress of Virology, Sapporo, in Sep., 2011.
• Yusuke Takahara reported his work in BBRC.
Takahara, Y., Matsuoka, S., Kuwano, T., Tsukamoto, T., Yamamoto, H., Ishii, H., Nakasone, T., Takeda, A., Inoue, M., Iida, A., Hara, H., Shu, T., Hasegawa, M., Sakawaki, H., Horiike, M., Miura, T., Igarashi, T., Naruse, T.K., Kimura, A., and Matano, T. Dominant induction of vaccine antigen-specific cytotoxic T lymphocyte responses after simian immunodeficiency virus challenge. Biochem. Biophys. Res. Commun. 408:615-619, 2011.
• Akatsuki Saito reported his work in Microbes Infect.
Saito, A., Nomaguchi, M., Iijima, S., Kuroishi, A., Yoshida, T., Lee, Y.-J., Hayakawa, T., Kono, K., Nakayama, E.E., Shioda, T., Yasutomi, Y., Adachi, A., Matano, T., and Akari, H. Improved capacity of a monkey-tropic HIV-1 derivative to replicate in cynomolgus monkeys with minimal modifications. Improved capacity of a monkey-tropic HIV-1 derivative to replicate in cynomolgus monkeys with minimal modifications. Microbes Infect. 13:58-64, 2011.
• Natsuko Inagaki reported her work in Retrovirology.
Inagaki, N., Takeuchi, H., Yokoyama, M., Sato, H., Ryo, A., Yamamoto, H., Kawada, M., and Matano, T. A structural constraint for functional interaction between N-terminal and C-terminal domains in simian immunodeficiency virus capsid proteins. Retrovirology 7:90, 2010.
• Nami Iwamoto reported her work in AIDS.
Iwamoto, N., Tsukamoto, T., Kawada, M., Takeda, A., Yamamoto, H., Takeuchi, H., and Matano, T. Broadening of CD8+ cell responses in vaccine-based simian immunodeficiency virus controllers. AIDS 24:2777-2787, 2010.
• Dr. Tetsuro Matano was appointed to Director, AIDS Research Center, NIID in Nov., 2010.
